Oligo-alpha-thymidylates covalently linked to intercalating agents: circular dichroism studies of their interaction with complementary sequences.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 8324010)

Published in Bioconjug Chem on August 09, 1993

Authors

M Durand1, J C Maurizot, U Asseline, N T Thuong, C Hélène

Author Affiliations

1: Centre de Biophysique Moléculaire, Orléans, France.

Articles by these authors

Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative. Nucleic Acids Res (1987) 4.36

Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides. Proc Natl Acad Sci U S A (1984) 3.03

Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation. Proc Natl Acad Sci U S A (1988) 2.82

Lac repressor binding to poly (d(A-T)). Conformational changes. Biochem Biophys Res Commun (1974) 2.49

Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents. Nucleic Acids Res (1987) 2.41

Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide. Proc Natl Acad Sci U S A (1991) 2.40

Specific inhibition of transcription by triple helix-forming oligonucleotides. Proc Natl Acad Sci U S A (1992) 2.38

G-quadruplex DNA: a target for drug design. Nat Med (1998) 2.38

Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates. Proc Natl Acad Sci U S A (1989) 2.38

Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatches. Biochemistry (1992) 2.29

Interactions between functional groups in protein-nucleic acid associations. Prog Biophys Mol Biol (1982) 2.14

Specific inhibition of mRNA translation by complementary oligonucleotides covalently linked to intercalating agents. Proc Natl Acad Sci U S A (1986) 2.14

Rate of degradation of [alpha]- and [beta]-oligodeoxynucleotides in Xenopus oocytes. Implications for anti-messenger strategies. Nucleic Acids Res (1987) 2.10

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence. J Biol Chem (1992) 2.00

Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res (1989) 1.98

Oligodeoxynucleotides covalently linked to intercalating dyes as base sequence-specific ligands. Influence of dye attachment site. EMBO J (1984) 1.97

Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate. Proc Natl Acad Sci U S A (1989) 1.96

Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo. Nat Biotechnol (2001) 1.91

Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances. Biochimie (1986) 1.90

Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion. Proc Natl Acad Sci U S A (1987) 1.88

Sequence-specific recognition of the major groove of DNA by oligodeoxynucleotides via triple helix formation. Footprinting studies. Nucleic Acids Res (1988) 1.85

Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides. Nature (1990) 1.84

Stability of triple helices containing RNA and DNA strands: experimental and molecular modeling studies. Nucleic Acids Res (1993) 1.84

Circular dichroism studies of an oligodeoxyribonucleotide containing a hairpin loop made of a hexaethylene glycol chain: conformation and stability. Nucleic Acids Res (1990) 1.83

Triple helix-specific ligands. Science (1992) 1.83

Selective inhibition of the cytopathic effect of type A influenza viruses by oligodeoxynucleotides covalently linked to an intercalating agent. Nucleic Acids Res (1987) 1.75

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proc Natl Acad Sci U S A (2002) 1.75

Sequence specificity in triple-helix formation: experimental and theoretical studies of the effect of mismatches on triplex stability. Biochemistry (1991) 1.73

Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat. Chembiochem (2001) 1.70

Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides. Biochemistry (1975) 1.66

Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites. Proc Natl Acad Sci U S A (1993) 1.65

Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates. Proc Natl Acad Sci U S A (1991) 1.63

[New substances with high specific activity for nucleic acid sequences: oligodeoxynucleotides covalently linked to an intercalating agent]. C R Seances Acad Sci III (1983) 1.59

Inhibition of restriction endonuclease cleavage via triple helix formation by homopyrimidine oligonucleotides. Biochemistry (1989) 1.59

Triple-helix formation by oligonucleotides containing the three bases thymine, cytosine, and guanine. Proc Natl Acad Sci U S A (1992) 1.57

Lac repressor - lac operator interaction. Circular dichroism study. Nucleic Acids Res (1981) 1.56

Antimessenger oligodeoxyribonucleotides: an alternative to antisense RNA for artificial regulation of gene expression--a review. Gene (1988) 1.55

Oligonucleotide clamps arrest DNA synthesis on a single-stranded DNA target. Proc Natl Acad Sci U S A (1993) 1.54

A tryptophan-containing peptide recognizes and cleaves DNA at apurinic sites. Nature (1981) 1.54

Targeted cleavage of polynucleotides by complementary oligonucleotides covalently linked to iron-porphyrins. Biochemistry (1986) 1.51

Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay. Proc Natl Acad Sci U S A (2001) 1.48

Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation. Proc Natl Acad Sci U S A (1996) 1.46

Sequence-targeted cleavage of single- and double-stranded DNA by oligothymidylates covalently linked to 1,10-phenanthroline. J Biol Chem (1989) 1.45

Triple helix formation and the antigene strategy for sequence-specific control of gene expression. Biochim Biophys Acta (1999) 1.44

An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites. Gene (1987) 1.43

Interactions of oligopeptides with nucleic acids. CRC Crit Rev Biochem (1981) 1.43

Inhibition of simian virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent. Nucleic Acids Res (1990) 1.42

Conformation and thermodynamic properties of oligocytidylic acids. J Mol Biol (1967) 1.40

Hydrogen-bonding contacts in the major groove are required for human immunodeficiency virus type-1 tat protein recognition of TAR RNA. J Mol Biol (1993) 1.38

Double helices with parallel strands are formed by nuclease-resistant oligo-[alpha]-deoxynucleotides and oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent with complementary oligo-[beta]-deoxynucleotides. J Mol Biol (1987) 1.38

Oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent. Double helices with parallel strands are formed with complementary oligo-[beta]-deoxynucleotides. Nucleic Acids Res (1987) 1.37

Anti-messenger oligodeoxynucleotides: specific inhibition of rabbit beta-globin synthesis in wheat germ extracts and Xenopus oocytes. Biochimie (1986) 1.36

Conformational stability of dinucleotides in solution. J Mol Biol (1967) 1.34

Extension of the range of recognition sequences for triple helix formation by oligonucleotides containing guanines and thymines. C R Acad Sci III (1991) 1.30

Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism. Nucleic Acids Res (1991) 1.29

Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif. Nucleic Acids Res (1994) 1.29

Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation. Nucleic Acids Res (1992) 1.27

Sequence-targeted chemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins. Nucleic Acids Res (1987) 1.24

Oligonucleotide directed triple helix formation. Curr Opin Struct Biol (1996) 1.23

Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation. EMBO J (1991) 1.22

Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes. Nucleic Acids Res (2001) 1.22

Specific recognition of single-stranded nucleic acids. Interaction of tryptophan-containing peptides with native, denatured, and ultraviolet-irradiated DNA. J Biol Chem (1977) 1.20

Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities. J Am Chem Soc (2001) 1.18