Published in Nucleic Acids Res on July 11, 1993
Relationship between internucleotide linkage geometry and the stability of RNA. RNA (1999) 5.01
Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions. RNA (2006) 1.81
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res (2000) 1.80
Pathogenesis of hepatitis C virus infection in Tupaia belangeri. J Virol (2010) 1.17
Kinetic analysis of delta ribozyme cleavage. Biochemistry (1998) 1.10
Metal binding motif in the active site of the HDV ribozyme binds divalent and monovalent ions. Biochemistry (2011) 1.07
Analysis of the cleavage reaction of a trans-acting human hepatitis delta virus ribozyme. Nucleic Acids Res (1997) 1.03
Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement. RNA (1999) 1.02
Imino proton NMR analysis of HDV ribozymes: nested double pseudoknot structure and Mg2+ ion-binding site close to the catalytic core in solution. Nucleic Acids Res (2002) 1.01
Distinct reaction pathway promoted by non-divalent-metal cations in a tertiary stabilized hammerhead ribozyme. RNA (2007) 1.00
Characterization of the Structure and Dynamics of the HDV Ribozyme at Different Stages Along the Reaction Path. J Phys Chem Lett (2011) 0.98
Thio effects and an unconventional metal ion rescue in the genomic hepatitis delta virus ribozyme. Biochemistry (2013) 0.97
Modulating RNA structure and catalysis: lessons from small cleaving ribozymes. Cell Mol Life Sci (2009) 0.96
Metal ions: supporting actors in the playbook of small ribozymes. Met Ions Life Sci (2011) 0.93
Competition between Co(NH(3)(6)3+ and inner sphere Mg2+ ions in the HDV ribozyme. Biochemistry (2009) 0.91
Two distinct catalytic strategies in the hepatitis δ virus ribozyme cleavage reaction. Biochemistry (2011) 0.88
Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ions. Nucleic Acids Res (2001) 0.88
Energetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozyme. EMBO J (2001) 0.88
Endogenous polyamine function--the RNA perspective. Nucleic Acids Res (2014) 0.84
Quantum Mechanical/Molecular Mechanical Study of the HDV Ribozyme: Impact of the Catalytic Metal Ion on the Mechanism. J Phys Chem Lett (2011) 0.81
Enhancement of Neurospora VS ribozyme cleavage by tuberactinomycin antibiotics. EMBO J (1995) 0.79
Assessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM. RNA (2015) 0.76
Exploiting cis-acting replication elements to direct hepatitis C virus-dependent transgene expression. J Virol (2005) 0.75
A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation. ACS Catal (2016) 0.75
A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA. Nature (1991) 5.26
Antigenomic RNA of human hepatitis delta virus can undergo self-cleavage. J Virol (1988) 4.59
Molecular cloning and sequencing of a human hepatitis delta (delta) virus RNA. Nature (1987) 4.52
Characterization of self-cleaving RNA sequences on the genome and antigenome of human hepatitis delta virus. J Virol (1988) 4.05
The chemistry of self-splicing RNA and RNA enzymes. Science (1987) 3.72
Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry (1991) 3.31
Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli. Biochemistry (1986) 2.68
Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature (1993) 2.62
Evolution in vitro of an RNA enzyme with altered metal dependence. Nature (1993) 2.50
Influence of metal ions on the ribonuclease P reaction. Distinguishing substrate binding from catalysis. J Biol Chem (1992) 2.18
Secondary structure of the self-cleaving RNA of hepatitis delta virus: applications to catalytic RNA design. Biochemistry (1992) 1.86
Reversible cleavage and ligation of hepatitis delta virus RNA. Science (1989) 1.59
Self-cleavage of hepatitis delta virus genomic strand RNA is enhanced under partially denaturing conditions. Biochemistry (1990) 1.57
Elimination of adventitious metals. Methods Enzymol (1988) 1.41
Kinetics for reaction of a circularized intervening sequence with CU, UCU, CUCU, and CUCUCU: mechanistic implications from the dependence on temperature and on oligomer and Mg2+ concentrations. Biochemistry (1988) 1.35
Theoretical analyses on the role of Mg2+ ions in ribozyme reactions. FASEB J (1993) 1.24
Random mutations to evaluate the role of bases at two important single-stranded regions of genomic HDV ribozyme. Nucleic Acids Res (1992) 1.14
A trinucleotide can promote metal ion-dependent specific cleavage of RNA. Proc Natl Acad Sci U S A (1992) 1.09
Point and compensation mutations to evaluate essential stem structures of genomic HDV ribozyme. FASEB J (1993) 1.05
Deletion of internal sequence on the HDV-ribozyme: elucidation of functionally important single-stranded loop regions. Nucleic Acids Res (1992) 1.04
Self-cleavage of a 71 nucleotide-long ribozyme derived from hepatitis delta virus genomic RNA. Nucleic Acids Res (1991) 1.01
Modification interference analysis of a self-cleaving RNA from hepatitis delta virus. FASEB J (1993) 1.00
Preferential chelation of cationic ligands to axial-equatorial oxygens over equatorial-equatorial dianionic oxygens: implication to the mechanism of action of ribozymes. Nucleic Acids Symp Ser (1991) 0.92
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature (1997) 13.77
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature (1996) 10.67
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature (1990) 8.94
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38
Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature (2000) 7.15
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron (2000) 6.33
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature (1999) 6.23
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med (2001) 5.52
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med (2001) 4.50
Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc Natl Acad Sci U S A (1993) 4.35
Requirement of c-kit for development of intestinal pacemaker system. Development (1992) 4.11
Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development (1998) 3.94
Expression and function of c-kit in hemopoietic progenitor cells. J Exp Med (1991) 3.48
c-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tissue Res (1995) 3.22
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. Blood (1992) 3.15
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell (2001) 2.97
Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20. Cell (2000) 2.84
Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. Science (1994) 2.78
Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nat Med (1998) 2.66
Molecular relationship of chromosomal genes encoding biphenyl/polychlorinated biphenyl catabolism: some soil bacteria possess a highly conserved bph operon. J Bacteriol (1989) 2.63
In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity (1998) 2.54
Interleukin 7 production and function in stromal cell-dependent B cell development. J Exp Med (1989) 2.49
In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development. EMBO J (1991) 2.48
Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. Opt Express (2005) 2.48
Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and function. Development (1991) 2.35
Joining of ribooligonucleotides with T4 RNA ligase and identification of the oligonucleotide-adenylate intermediate. Nucleic Acids Res (1976) 2.31
Reovirus as an oncolytic agent against experimental human malignant gliomas. J Natl Cancer Inst (2001) 2.27
Enhanced proliferative potential in culture of cells from p53-deficient mice. Oncogene (1993) 2.25
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Nature (1998) 2.25
B lymphopoiesis on stromal cell clone: stromal cell clones acting on different stages of B cell differentiation. Eur J Immunol (1988) 2.20
Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development (2001) 2.19
Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med (1999) 2.13
PDGF mediates a neuron-astrocyte interaction in the developing retina. Neuron (1996) 2.10
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood (1991) 2.02
Pseudomonas putida KF715 bphABCD operon encoding biphenyl and polychlorinated biphenyl degradation: cloning, analysis, and expression in soil bacteria. J Bacteriol (1990) 1.97
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol (1999) 1.96
Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis. J Bacteriol (1990) 1.95
Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene (1995) 1.94
IL-7 receptor alpha+ CD3(-) cells in the embryonic intestine induces the organizing center of Peyer's patches. Int Immunol (1999) 1.91
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. Nature (2000) 1.89
Two RNA species co-purify with RNase P from the fission yeast Schizosaccharomyces pombe. EMBO J (1986) 1.88
Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Dev Growth Differ (1997) 1.79
Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J Exp Med (1993) 1.75
Involvement of the c-kit receptor in the adhesion of hematopoietic stem cells to stromal cells. Exp Hematol (1994) 1.74
Expression of alpha(4)beta(7) integrin defines a distinct pathway of lymphoid progenitors committed to T cells, fetal intestinal lymphotoxin producer, NK, and dendritic cells. J Immunol (2001) 1.73
Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor. J Exp Med (1998) 1.70
Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells. Int Immunol (2001) 1.68
A monoclonal antibody against Igh6-4 determinant. Immunogenetics (1986) 1.68
Requirement of Runx1/AML1/PEBP2alphaB for the generation of haematopoietic cells from endothelial cells. Genes Cells (2001) 1.65
Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for beta-globin locus control region complex. J Biol Chem (1998) 1.64
Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA. Proc Natl Acad Sci U S A (1981) 1.63
Maturation of embryonic stem cells into endothelial cells in an in vitro model of vasculogenesis. Blood (1999) 1.63
Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter. Hum Gene Ther (2000) 1.62
Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum. Mol Cell Biol (1991) 1.62
Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor. Blood (1993) 1.62
Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules. J Exp Med (1990) 1.56
Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J Exp Med (2001) 1.53
Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transport. J Cell Biol (1991) 1.53
Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture. Nature (1991) 1.51
p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev (1998) 1.50
PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5. J Histochem Cytochem (1997) 1.49
Rhythmic Cl- current and physiological roles of the intestinal c-kit-positive cells. Pflugers Arch (1995) 1.49
A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. Blood (1989) 1.48
Cloning of a Sphingomonas paucimobilis SYK-6 gene encoding a novel oxygenase that cleaves lignin-related biphenyl and characterization of the enzyme. Appl Environ Microbiol (1998) 1.45
Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors. Development (1998) 1.44
Cloning and sequencing of the gene for a Pseudomonas paucimobilis enzyme that cleaves beta-aryl ether. J Bacteriol (1991) 1.44
Reconstitution of chemically synthesized ribooligonucleotides with naturally occurring tRNA fragments. Eur J Biochem (1976) 1.44
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages. Nucleic Acids Res (1993) 1.44
Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking. Proc Natl Acad Sci U S A (1997) 1.43
Purification of T4 RNA ligase by 2', 5'-ADP sepharose chromatography. FEBS Lett (1979) 1.42
The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis. Mol Cell Biol (1999) 1.42
Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse. Nucleic Acids Res (1991) 1.40
Genetic and biochemical characterization of a 2-pyrone-4, 6-dicarboxylic acid hydrolase involved in the protocatechuate 4, 5-cleavage pathway of Sphingomonas paucimobilis SYK-6. J Bacteriol (1999) 1.38
Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin. EMBO J (1991) 1.38
Functional blockade of platelet-derived growth factor receptor-beta but not of receptor-alpha prevents vascular smooth muscle cell accumulation in fibrous cap lesions in apolipoprotein E-deficient mice. Circulation (2001) 1.38
A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs. Nucleic Acids Res (2000) 1.37
Stage-specific expression of the Kit receptor and its ligand (KL) during male gametogenesis in the mouse: a Kit-KL interaction critical for meiosis. Development (1998) 1.37
Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor. Am J Pathol (1991) 1.35