Published in Proc Natl Acad Sci U S A on July 15, 1993
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J (1998) 6.65
Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci U S A (1996) 6.04
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol (1996) 5.75
Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc Natl Acad Sci U S A (1995) 4.60
Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. EMBO J (1994) 4.55
Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J (2001) 2.98
The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc Natl Acad Sci U S A (1998) 2.85
The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics (1996) 2.79
Activities of human recombination protein Rad51. Proc Natl Acad Sci U S A (1997) 2.39
p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J (1996) 2.25
The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. PLoS One (2007) 1.83
Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J (1997) 1.82
RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes. J Cell Biol (1999) 1.81
recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1996) 1.76
The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis. Nucleic Acids Res (1996) 1.75
Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res (1998) 1.70
A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair. Mol Cell Biol (2000) 1.69
RecA-like proteins are components of early meiotic nodules in lily. Proc Natl Acad Sci U S A (1997) 1.59
Three-dimensional microscopy of the Rad51 recombination protein during meiotic prophase. Plant Cell (1999) 1.57
Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase. Mol Cell Biol (1997) 1.54
Rad51 expression and localization in B cells carrying out class switch recombination. Proc Natl Acad Sci U S A (1996) 1.50
Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase. Mol Cell Biol (1996) 1.45
Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis. Proc Natl Acad Sci U S A (2004) 1.40
Sequestration of mammalian Rad51-recombination protein into micronuclei. J Cell Biol (1999) 1.33
Mitochondria-related male infertility. Proc Natl Acad Sci U S A (2006) 1.32
The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination. Mol Cell Biol (1997) 1.29
Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res (1998) 1.27
RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors. Nucleic Acids Res (2001) 0.92
RAD51 mutants cause replication defects and chromosomal instability. Mol Cell Biol (2012) 0.91
Role of recombination enzymes in mammalian cell survival. Proc Natl Acad Sci U S A (1996) 0.87
Reverse genetic studies of mitochondrial DNA-based diseases using a mouse model. Proc Jpn Acad Ser B Phys Biol Sci (2008) 0.76
Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair. Nucleic Acids Res (2016) 0.75
Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing. Sci Rep (2016) 0.75
Identification of more than two paternal haplotypes of the ovine fatty acid-binding protein 4 (FABP4) gene in half-sib families: evidence of intragenic meiotic recombination. PLoS One (2014) 0.75
Plant DNA recombinases: a long way to go. J Nucleic Acids (2009) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J (1982) 38.14
The double-strand-break repair model for recombination. Cell (1983) 31.21
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell (1992) 10.78
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell (1992) 10.48
The V(D)J recombination activating gene, RAG-1. Cell (1989) 9.79
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science (1990) 9.33
Hereditary anemias of the mouse: a review for geneticists. Adv Genet (1979) 6.91
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae. Microbiol Rev (1988) 4.75
V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell (1992) 4.41
The RecA protein: structure and function. Crit Rev Biochem Mol Biol (1990) 4.33
Homologous recombination in mammalian cells. Annu Rev Genet (1989) 4.17
Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol Cell Biol (1992) 4.04
Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol Cell Biol (1992) 3.74
A link between double-strand break-related repair and V(D)J recombination: the scid mutation. Proc Natl Acad Sci U S A (1991) 2.68
Biochemistry of genetic recombination: energetics and mechanism of DNA strand exchange. Annu Rev Biophys Biophys Chem (1991) 2.29
Double-strand gap repair in a mammalian gene targeting reaction. Mol Cell Biol (1991) 2.28
The role and fate of DNA ends for homologous recombination in embryonic stem cells. Mol Cell Biol (1992) 1.71
Highly degenerate, inosine-containing primers specifically amplify rare cDNA using the polymerase chain reaction. Nucleic Acids Res (1988) 1.50
Detection of somatic DNA recombination in the transgenic mouse brain. Science (1991) 1.33
Functional structures of the recA protein found by chimera analysis. J Mol Biol (1992) 1.27
Nucleotide sequence of mouse Tcp-1a cDNA. Gene (1991) 0.93
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell (2001) 18.68
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell (1996) 15.19
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol (2001) 13.98
Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids (1970) 11.81
Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ (2004) 9.96
The complete sequence of the rice (Oryza sativa) chloroplast genome: intermolecular recombination between distinct tRNA genes accounts for a major plastid DNA inversion during the evolution of the cereals. Mol Gen Genet (1989) 9.53
Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol Teratol (1997) 8.51
A perpendicular-anisotropy CoFeB-MgO magnetic tunnel junction. Nat Mater (2010) 7.78
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J (1998) 7.59
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science (1997) 7.31
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem (1991) 7.04
Hospital-acquired candidemia. The attributable mortality and excess length of stay. Arch Intern Med (1988) 6.78
Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization. J Immunol (1980) 6.69
Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci U S A (1996) 6.04
Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics. Antimicrob Agents Chemother (1989) 5.98
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature (2000) 5.71
Kaplan-Meier, marginal or conditional probability curves in summarizing competing risks failure time data? Stat Med (1993) 4.60
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells. Mol Biol Cell (2000) 4.22
Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy. Science (1995) 3.66
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci U S A (2001) 3.49
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin. J Biol Chem (1998) 3.39
Proposals of Sphingomonas paucimobilis gen. nov. and comb. nov., Sphingomonas parapaucimobilis sp. nov., Sphingomonas yanoikuyae sp. nov., Sphingomonas adhaesiva sp. nov., Sphingomonas capsulata comb. nov., and two genospecies of the genus Sphingomonas. Microbiol Immunol (1990) 3.33
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol Cell Biol (1999) 3.17
Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells. Biochem Biophys Res Commun (1999) 3.03
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. Proc Natl Acad Sci U S A (1987) 2.99
Risk factors for hospital-acquired candidemia. A matched case-control study. Arch Intern Med (1989) 2.97
Contralateral thalamic perfusion in patients with reflex sympathetic dystrophy syndrome. Lancet (1999) 2.93
Virulence for mice of Klebsiella strains belonging to the O1 group: relationship to their capsular (K) types. Infect Immun (1983) 2.93
Neurobehavioral deficits associated with PCB in 7-year-old children prenatally exposed to seafood neurotoxicants. Neurotoxicol Teratol (2001) 2.85
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron (1995) 2.82
Quantification of antigen specific CD8+ T cells using an ELISPOT assay. J Immunol Methods (1995) 2.82
Definition of an epitope and MHC class I molecule recognized by gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys. J Immunol (1991) 2.77
BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing. J Med Genet (2004) 2.75
Characterization of rec7, an early meiotic recombination gene in Schizosaccharomyces pombe. Genetics (2001) 2.74
Effects of statin therapy on abdominal aortic aneurysm growth: a meta-analysis and meta-regression of observational comparative studies. Eur J Vasc Endovasc Surg (2012) 2.72
A novel gene activated in regenerating islets. J Biol Chem (1988) 2.71
Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis (2002) 2.69
The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology (1994) 2.68
Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties. Antimicrob Agents Chemother (1974) 2.68
Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science (1993) 2.63
Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum (2000) 2.61
Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol (1993) 2.56
Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defectiva comb. nov., respectively. Int J Syst Bacteriol (1995) 2.55
Aggressive preoperative management and extended surgery for hilar cholangiocarcinoma: Nagoya experience. J Hepatobiliary Pancreat Surg (2000) 2.55
Sodium channels SCN1A, SCN2A and SCN3A in familial autism. Mol Psychiatry (2003) 2.48
Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5'-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J Clin Invest (1987) 2.48
A spin-valve-like magnetoresistance of an antiferromagnet-based tunnel junction. Nat Mater (2011) 2.47
Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae. Mol Gen Genet (1989) 2.46
A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res (1997) 2.46
Protein disulfide-isomerase in rat exocrine pancreatic cells is exported from the endoplasmic reticulum despite possessing the retention signal. J Biol Chem (1990) 2.44
DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem (1996) 2.38
Therapeutic effects of ML-236B in primary hypercholesterolemia. Atherosclerosis (1980) 2.35
Evaluation of liver tumors using fluorine-18-fluorodeoxyglucose PET: characterization of tumor and assessment of effect of treatment. J Nucl Med (1992) 2.30
Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci U S A (1992) 2.29
Complications of double balloon enteroscopy: a multicenter survey. Endoscopy (2007) 2.28
The three-dimensional structure of aquaporin-1. Nature (1997) 2.28
Objective system for interviewer performance evaluation for use in epidemiologic studies. Am J Epidemiol (1994) 2.28
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum Genet (1998) 2.27
Template engineering of Co-doped BaFe2As2 single-crystal thin films. Nat Mater (2010) 2.22
Surface of bacteriorhodopsin revealed by high-resolution electron crystallography. Nature (1997) 2.22
Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (1995) 2.21
Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J Biol Chem (1997) 2.20
Overexpression of cyclooxygenase-2 in carcinoma of the pancreas. Clin Cancer Res (1999) 2.20
Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia. Science (1993) 2.17
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer (2008) 2.13
hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria. Cell Death Differ (2004) 2.13
Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library. Genes Cells (2000) 2.12
A new computer-assisted method for measuring the tibio-femoral angle in patients with osteoarthritis of the knee. Osteoarthritis Cartilage (2004) 2.11
Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men. Kidney Int (2006) 2.10
Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc Natl Acad Sci U S A (1996) 2.10
In vitro and in vivo antibacterial activities of ME1207, a new oral cephalosporin. Antimicrob Agents Chemother (1988) 2.08
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J Clin Invest (2001) 2.07
The structure of bacteriorhodopsin at 3.0 A resolution based on electron crystallography: implication of the charge distribution. J Mol Biol (1999) 2.07
Oxidative stress inhibits the repair of photodamage to the photosynthetic machinery. EMBO J (2001) 2.06
Endoscopic correction of intussusception and removal of a colonic lipoma. Gastrointest Endosc (1990) 2.04
Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol (2000) 2.04
A new method for rapid mapping of the retinal thickness at the posterior pole. Invest Ophthalmol Vis Sci (1996) 2.03
Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma. Clin Cancer Res (1999) 2.03
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Nature (1981) 2.02
Antioxidative and anti-glycation activity of garcinol from Garcinia indica fruit rind. J Agric Food Chem (2000) 2.01
The discontinuation of life support measures in patients in a permanent vegetative state. Neurol Sci (2002) 2.00
Enlargement of spontaneous intracerebral hemorrhage. Incidence and time course. Stroke (1996) 2.00
Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells. Mol Gen Genet (1996) 2.00
Lymph node metastasis from hilar cholangiocarcinoma: audit of 110 patients who underwent regional and paraaortic node dissection. Ann Surg (2001) 1.99
Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases. Cancer Res (2001) 1.98
Stat6 regulation of in vivo IL-4 responses. J Immunol (2000) 1.97
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology (1998) 1.97
Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles. J Cell Biol (1977) 1.97
Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3. Biochem Biophys Res Commun (1997) 1.97
A carbonic anhydrase from the nacreous layer in oyster pearls. Proc Natl Acad Sci U S A (1996) 1.97
Early treatment with ganciclovir to prevent cytomegalovirus disease after allogeneic bone marrow transplantation. N Engl J Med (1991) 1.96
Immunological response restricts number of cells in sensory ganglia infected with herpes simplex virus. Nature (1976) 1.95