Published in Gut on July 01, 1993
Granulation tissue as a contractile organ. A study of structure and function. J Exp Med (1972) 5.42
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia (1971) 5.14
Contraction of granulation tissue in vitro: similarity to smooth muscle. Science (1971) 3.29
The smooth muscle cell. I. In vivo synthesis of connective tissue proteins. J Cell Biol (1971) 2.74
Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. Lab Invest (1989) 2.30
Chronic intestinal pseudo-obstruction. A report of 27 cases and review of the literature. Medicine (Baltimore) (1981) 1.89
Fine structural changes in uterine smooth muscle and fibroblasts in response to estrogen. J Cell Biol (1967) 1.68
Pathology of neuromuscular disorders of the small intestine and colon. Gastroenterology (1987) 1.57
Studies of idiopathic intestinal pseudoobstruction. I. Hereditary hollow visceral myopathy: clinical and pathological studies. Gastroenterology (1977) 1.46
Studies of idiopathic intestinal pseudoobstruction. II. Hereditary hollow visceral myopathy: family studies. Gastroenterology (1977) 1.30
Pathologic features of familial visceral myopathy. Hum Pathol (1982) 1.21
Collagenous colitis: a disease of pericryptal fibroblast sheath? J Pathol (1986) 1.17
Contractile cells in normal and fibrotic lung. Lab Invest (1989) 1.13
Colonic pericrypt sheath cells: characterisation of cell type with new monoclonal antibody. J Clin Pathol (1987) 1.11
Familial visceral myopathy. Evidence of diffuse involvement of intestinal smooth muscle. Am J Surg Pathol (1987) 1.11
The intermediate filament cytoskeleton of myofibroblasts: an immunofluorescence and ultrastructural study. Virchows Arch A Pathol Anat Histopathol (1984) 1.10
Organisation of experimental thrombosis by blood cells. Evidence of the transformation of mononuclear cells into myofibroblasts and endothelial cells. Virchows Arch A Pathol Anat Histopathol (1985) 0.95
The myofibroblast. Pathol Annu (1980) 0.95
The cytoskeleton and extracellular matrix of the Dupuytren's disease "myofibroblast": an immunofluorescence study of a nonmuscle cell type. J Hand Surg Am (1986) 0.92
The 'transitional' mucosa adjacent to large bowel carcinoma--electron microscopic features and myofibroblast reaction. Histopathology (1982) 0.85
Myofibroblasts. J Pathol (1990) 0.79
Rare type of visceral myopathy mimicking anorexia nervosa. J R Soc Med (1990) 0.78
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature (1984) 17.70
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet (2012) 17.29
El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2000) 15.38
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (1985) 13.79
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12
Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid (1981) 9.00
The economic burden of back pain in the UK. Pain (2000) 6.79
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J (1986) 6.62
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature (1998) 6.49
Randomised trial of oral and intravenous methylprednisolone in acute relapses of multiple sclerosis. Lancet (1997) 4.43
Current cost of medical negligence in NHS hospitals: analysis of claims database. BMJ (2000) 4.25
Randomised controlled trial comparing hospital at home care with inpatient hospital care. I: three month follow up of health outcomes. BMJ (1998) 3.82
Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe. EMBO J (1984) 3.74
Sphincter denervation in anorectal incontinence and rectal prolapse. Gut (1977) 3.66
Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor. Nature (1983) 3.43
Randomised controlled trial of laparoscopic versus open repair of inguinal hernia: early results. BMJ (1995) 3.37
Increased motor unit fibre density in the external anal sphincter muscle in ano-rectal incontinence: a single fibre EMG study. J Neurol Neurosurg Psychiatry (1980) 3.36
Injury to innervation of pelvic floor sphincter musculature in childbirth. Lancet (1984) 3.27
Phase II/III randomized trial of TCH346 in patients with ALS. Neurology (2007) 3.22
Randomised controlled trial comparing hospital at home care with inpatient hospital care. II: cost minimisation analysis. BMJ (1998) 3.21
The future of general medicine: lessons from an admissions ward. J R Coll Physicians Lond (1998) 3.19
Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature (1983) 3.17
Genetic variation in the human insulin gene. Science (1980) 3.13
The pelvic floor musculature in the descending perineum syndrome. Br J Surg (1982) 3.06
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1. Biochem J (1999) 3.03
Physiological studies of the anal sphincter musculature in faecal incontinence and rectal prolapse. Br J Surg (1981) 3.00
The distribution of health care costs and their statistical analysis for economic evaluation. J Health Serv Res Policy (1998) 2.94
Pathogenesis of ano-rectal incontinence. A histometric study of the anal sphincter musculature. J Neurol Sci (1979) 2.87
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci U S A (1996) 2.77
Organization and modulation of nuclear lamina structure. J Cell Sci Suppl (1984) 2.75
Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence. Br J Surg (1984) 2.73
Randomised controlled trial of an interactive multimedia decision aid on benign prostatic hypertrophy in primary care. BMJ (2001) 2.71
Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers. Am J Pathol (1993) 2.69
A randomised controlled trial and cost analysis of problem-solving treatment for emotional disorders given by community nurses in primary care. Br J Psychiatry (1997) 2.56
Structure and sequence of the Drosophila zeste gene. EMBO J (1987) 2.55
Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging. J Neurol Neurosurg Psychiatry (2000) 2.55
Insulin-like growth factor II precursor gene organization in relation to insulin gene family. Nature (1984) 2.53
Isolation of vascular smooth muscle cells from a single murine aorta. Methods Cell Sci (2001) 2.48
Antibodies against human putamen in children with Tourette syndrome. Neurology (1998) 2.43
Measuring the impact of menopausal symptoms on quality of life. BMJ (1993) 2.42
Routine colonic lavage is unnecessary for double-contrast barium enema in outpatients. Br Med J (Clin Res Ed) (1982) 2.41
Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results. Br J Cancer (1975) 2.39
Effect of vaginal delivery on the pelvic floor: a 5-year follow-up. Br J Surg (1990) 2.36
The use of out of hours health services: a cross sectional survey. BMJ (1998) 2.36
Zeste encodes a sequence-specific transcription factor that activates the Ultrabithorax promoter in vitro. Cell (1988) 2.34
Randomised controlled trial of an interactive multimedia decision aid on hormone replacement therapy in primary care. BMJ (2001) 2.30
Effect of colesevelam on faecal bile acids and bowel functions in diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther (2015) 2.13
HRT: an analysis of benefits, risks and costs. Br Med Bull (1992) 2.11
Assessment of pelvic-floor disorders and incontinence by electrophysiological recording of the anal reflex. Lancet (1978) 2.09
Progressive encephalomyelitis with rigidity. Brain (1976) 2.09
Electrophysiological study of motor nerve supply of pelvic floor. Lancet (1981) 2.08
Cost of poor adherence to anti-hypertensive therapy in five European countries. Eur J Health Econ (2014) 2.06
Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype. Proc Natl Acad Sci U S A (1977) 1.97
Perineal nerve damage in genuine stress urinary incontinence. An electrophysiological study. Br J Urol (1985) 1.88
Quality of life in multiple sclerosis in France, Germany, and the United Kingdom. Cost of Multiple Sclerosis Study Group. J Neurol Neurosurg Psychiatry (1998) 1.84
Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia. Neurosci Lett (1992) 1.82
Mitochondrial encephalomyopathies: biochemical studies in two cases revealing defects in the respiratory chain. Brain (1982) 1.80
Nucleotide sequence of human preproinsulin complementary DNA. Science (1980) 1.80
The economic burden of coronary heart disease in the UK. Heart (2002) 1.78
Ubiquitin deposits in anterior horn cells in motor neurone disease. Neurosci Lett (1988) 1.77
Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain (1991) 1.74
Digital subtraction angiography (DSA) of the extracranial cerebral vessels: a direct comparison between intravenous and intra-arterial DSA. Clin Radiol (1991) 1.74
Autosomal recessive congenital intrauterine infection-like syndrome of microcephaly, intracranial calcification, and CNS disease. Am J Med Genet (1994) 1.72
Motor conduction velocity in the human spinal cord: slowed conduction in multiple sclerosis and radiation myelopathy. J Neurol Neurosurg Psychiatry (1985) 1.70
Cost of cardiovascular diseases in the United Kingdom. Heart (2006) 1.70
Automated hemagglutination assays. Ann N Y Acad Sci (1965) 1.68
The pathology of the human muscle spindle: effect of denervation. J Neurol Sci (1974) 1.68
Frequency of occurrence of idiotypes associated with anti-p-azophenylarsonate antibodies arising in mice immunologically suppressed with respect to a cross-reactive idiotype. J Exp Med (1977) 1.67
Longitudinal sliding of the median nerve during movements of the upper limb. J Neurol Neurosurg Psychiatry (1976) 1.65
Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains. EMBO J (1989) 1.64
Isolation of a cDNA clone coding for the gamma-subunit of mouse nerve growth factor using a high-stringency selection procedure. DNA (1984) 1.64
Damage to the innervation of the voluntary anal and periurethral sphincter musculature in incontinence: an electrophysiological study. J Neurol Neurosurg Psychiatry (1984) 1.62
Unifying concept of pelvic floor disorders and incontinence. J R Soc Med (1985) 1.60
Fibrinogen. Int J Biochem Cell Biol (1999) 1.57
The syndrome of transient global amnesia. Brain (1973) 1.56
Estimating the relationship between disease progression and cost of care in dementia. Br J Psychiatry (2002) 1.55
Variation in the sequence and modification state of the human insulin gene flanking regions. Nucleic Acids Res (1982) 1.55
Normal proximal and delayed distal conduction in the pudendal nerves of patients with idiopathic (neurogenic) faecal incontinence. J Neurol Neurosurg Psychiatry (1984) 1.55
Blood glucose self-monitoring in type 2 diabetes: a randomised controlled trial. Health Technol Assess (2009) 1.54
Changes in motor unit synchronization following central nervous lesions in man. J Physiol (1993) 1.54
Bilateral renal cell carcinoma in the Birt-Hogg-Dubé syndrome. J Am Acad Dermatol (1993) 1.53
Treatment of acute exacerbations of multiple sclerosis with intravenous methyl-prednisolone. J Neurol Neurosurg Psychiatry (1982) 1.53
Evidence of pudendal neuropathy in patients with perineal descent and chronic straining at stool. Gut (1984) 1.52
Tyramine activates the EEG in epileptic patients. Nature (1975) 1.51
Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses. J Biol Chem (1999) 1.49
Position sense in a damaged knee. J Neurol Neurosurg Psychiatry (1986) 1.48
Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory. Behav Neurosci (2007) 1.48
Electroencephalographic criteria of hypocalcemia and hypercalcemia. Arch Neurol (1972) 1.47
Risk factors in childbirth causing damage to the pelvic floor innervation. Int J Colorectal Dis (1986) 1.47
Small deep cerebral infarcts associated with occlusive internal carotid artery disease. A hemodynamic phenomenon? Arch Neurol (1990) 1.46
Tuberculosis of the central nervous system. Q J Med (1984) 1.46
Faecal incontinence in myotonic dystrophy. J Neurol Neurosurg Psychiatry (1998) 1.45
Incidence and risk calculation of inotropic support in patients undergoing cardiac surgery with cardiopulmonary bypass using an automated anaesthesia record-keeping system. Br J Anaesth (2002) 1.44
Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement. Bone Joint J (2013) 1.43
Fluctuations in attention: PD dementia vs DLB with parkinsonism. Neurology (2002) 1.42
Myopathy due to epsilon amino-caproic acid. Muscle Nerve (1980) 1.42
The product of the Drosophila zeste gene binds to specific DNA sequences in white and Ubx. EMBO J (1987) 1.42
Estimating long-term cost savings from treatment of Alzheimer's disease. A modelling approach. Pharmacoeconomics (1999) 1.41
John Hughlings-Jackson: a sesquicentennial tribute. J Neurol Neurosurg Psychiatry (1986) 1.41