Published in Neurobiol Aging on October 04, 1993
Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc Natl Acad Sci U S A (1997) 2.96
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci U S A (2007) 2.87
Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome. Proc Natl Acad Sci U S A (2005) 2.72
Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proc Natl Acad Sci U S A (1996) 2.32
Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain (2013) 2.09
Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Ann Neurol (2005) 2.05
Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy. J Neurosci (2009) 2.00
Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proc Natl Acad Sci U S A (2004) 1.99
Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J Clin Invest (2005) 1.94
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS One (2011) 1.93
Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol (2010) 1.89
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proc Natl Acad Sci U S A (1999) 1.88
Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain (2010) 1.86
If you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3D space. J Anat (1996) 1.79
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol (2000) 1.66
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect Immun (1999) 1.65
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice. Mol Cell Biol (2008) 1.62
Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease. Exp Neurol (2012) 1.60
Anatomical gradients of adult neurogenesis and activity: young neurons in the ventral dentate gyrus are activated by water maze training. Hippocampus (2009) 1.49
Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice. Proc Natl Acad Sci U S A (2000) 1.47
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Eur J Neurosci (2009) 1.42
Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys. J Comp Neurol (2009) 1.39
A guide to neurotoxic animal models of Parkinson's disease. Cold Spring Harb Perspect Med (2011) 1.36
Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease. J Neuroinflammation (2006) 1.32
Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice. Proc Natl Acad Sci U S A (2006) 1.26
Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma. Proc Natl Acad Sci U S A (2005) 1.24
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest (2003) 1.24
Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat. Neurobiol Dis (2011) 1.21
Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem (2005) 1.19
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci (2013) 1.18
Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats. Eur J Neurosci (2007) 1.16
Causing and curing infantile esotropia in primates: the role of decorrelated binocular input (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2007) 1.16
Ischemic stroke in the elderly: an overview of evidence. Nat Rev Neurol (2010) 1.15
Methods to identify and characterize developmental neurotoxicity for human health risk assessment. II: neuropathology. Environ Health Perspect (2001) 1.13
Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease. J Comp Neurol (2001) 1.11
Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene. Proc Natl Acad Sci U S A (1999) 1.11
Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2. Hum Mol Genet (2012) 1.10
Rapid seasonal-like regression of the adult avian song control system. Proc Natl Acad Sci U S A (2007) 1.09
Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrow. Am J Pathol (2010) 1.09
Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation. J Cell Mol Med (2008) 1.09
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity. Neurobiol Dis (2007) 1.09
Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. Neurobiol Dis (2007) 1.08
Cortical glial fibrillary acidic protein-positive cells generate neurons after perinatal hypoxic injury. J Neurosci (2011) 1.07
Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. Am J Pathol (2011) 1.07
Substance P is expressed in hippocampal principal neurons during status epilepticus and plays a critical role in the maintenance of status epilepticus. Proc Natl Acad Sci U S A (1999) 1.06
Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus. Mol Cell Neurosci (2008) 1.05
Cutaneous overexpression of NT-3 increases sensory and sympathetic neuron number and enhances touch dome and hair follicle innervation. J Cell Biol (1996) 1.05
Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases. DNA Repair (Amst) (2008) 1.04
Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer. Neurobiol Aging (2009) 1.03
Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats. Brain Res (2008) 1.03
Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. PLoS One (2011) 1.00
Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice. PLoS One (2012) 1.00
Cortical and striatal neurone number in Huntington's disease. Acta Neuropathol (1994) 1.00
Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1. PLoS One (2010) 0.99
Experience-expectant plasticity in the mushroom bodies of the honeybee. Learn Mem (1999) 0.99
Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol Dis (2008) 0.99
α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation. J Neuroinflammation (2012) 0.98
An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease. J Neurosci (2007) 0.98
Avoidance perseveration during extinction training in Wistar-Kyoto rats: an interaction of innate vulnerability and stressor intensity. Behav Brain Res (2011) 0.98
Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors. J Ovarian Res (2010) 0.98
ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis. Am J Pathol (2004) 0.98
Environmental enrichment increases the GFAP+ stem cell pool and reverses hypoxia-induced cognitive deficits in juvenile mice. J Neurosci (2012) 0.97
Vocalization Induced CFos Expression in Marmoset Cortex. Front Integr Neurosci (2010) 0.97
Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons. Mol Neurodegener (2009) 0.97
Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Brain Res (2008) 0.95
Neurodegeneration in the somatosensory cortex after experimental diffuse brain injury. Brain Struct Funct (2011) 0.95
Volumetric correlates of spatiotemporal working and recognition memory impairment in aged rhesus monkeys. Cereb Cortex (2010) 0.95
ApoE is required for maintenance of the dentate gyrus neural progenitor pool. Development (2011) 0.94
Intrastriatal lipopolysaccharide injection induces parkinsonism in C57/B6 mice. J Neurosci Res (2009) 0.94
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. Drug Alcohol Depend (2007) 0.93
Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson's disease. Cell Death Differ (2013) 0.93
Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neurobiol Dis (2013) 0.93
Precursors with glial fibrillary acidic protein promoter activity transiently generate GABA interneurons in the postnatal cerebellum. Stem Cells (2009) 0.91
Developmental profiling of postnatal dentate gyrus progenitors provides evidence for dynamic cell-autonomous regulation. Hippocampus (2011) 0.91
Low-intensity repetitive transcranial magnetic stimulation improves abnormal visual cortical circuit topography and upregulates BDNF in mice. J Neurosci (2014) 0.91
Functional recovery of stepping in rats after a complete neonatal spinal cord transection is not due to regrowth across the lesion site. Neuroscience (2009) 0.90
Stereological estimation of the total number of myelinated callosal fibers in human subjects. J Anat (2011) 0.90
Low dose prenatal ethanol exposure induces anxiety-like behaviour and alters dendritic morphology in the basolateral amygdala of rat offspring. PLoS One (2013) 0.90
Photoperiodic condition is associated with region-specific expression of GNRH1 mRNA in the preoptic area of the male starling (Sturnus vulgaris). Biol Reprod (2009) 0.89
Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice. PLoS One (2011) 0.89
Restricted loss of olivocochlear but not vestibular efferent neurons in the senescent gerbil (Meriones unguiculatus). Front Aging Neurosci (2015) 0.89
Chronic hydrocephalus-induced hypoxia: increased expression of VEGFR-2+ and blood vessel density in hippocampus. Neuroscience (2007) 0.89
Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice. Neurobiol Dis (2010) 0.88
Motor impairments, striatal degeneration, and altered dopamine-glutamate interplay in mice lacking PSD-95. J Neurogenet (2014) 0.87
Neuronal populations in the basolateral nuclei of the amygdala are differentially increased in humans compared with apes: a stereological study. J Comp Neurol (2012) 0.87
Caspase inhibitor infusion protects an avian song control circuit from seasonal-like neurodegeneration. J Neurosci (2008) 0.87
Neuron numbers in the hypothalamus of the normal aging rhesus monkey: stability across the adult lifespan and between the sexes. J Comp Neurol (2012) 0.87
Polysialic acid is required for dopamine D2 receptor-mediated plasticity involving inhibitory circuits of the rat medial prefrontal cortex. PLoS One (2011) 0.86
Syndromics: a bioinformatics approach for neurotrauma research. Transl Stroke Res (2011) 0.86
Contribution of Egr1/zif268 to Activity-Dependent Arc/Arg3.1 Transcription in the Dentate Gyrus and Area CA1 of the Hippocampus. Front Behav Neurosci (2011) 0.85
Evidence for a regional specificity in the density and distribution of noradrenergic varicosities in rat cortex. J Comp Neurol (2013) 0.84
A novel use of combined tyrosine hydroxylase and silver nucleolar staining to determine the effects of a unilateral intrastriatal 6-hydroxydopamine lesion in the substantia nigra: a stereological study. J Neurosci Methods (2012) 0.84
Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration. Exp Neurol (2010) 0.84
Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease. Neurobiol Dis (2013) 0.83
A rapid fluorescent method to quantify neuronal loss after experimental intracerebral hemorrhage. J Neurosci Methods (2013) 0.83
Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging. Acta Neuropathol Commun (2015) 0.83
Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus (2010) 0.83
Stereological estimation of total cell numbers in the human cerebral and cerebellar cortex. Front Hum Neurosci (2014) 0.83
Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands. J Neurosci (2014) 0.83
Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol (1990) 3.96
Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet (1994) 3.67
Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging (1993) 2.38