Published in Proc Natl Acad Sci U S A on September 16, 1997
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes. Nat Biotechnol (2008) 6.82
Influence of leisure activity on the incidence of Alzheimer's disease. Neurology (2001) 4.49
Dynamics of hippocampal neurogenesis in adult humans. Cell (2013) 3.99
Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc Natl Acad Sci U S A (2003) 2.83
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron (2009) 2.72
Adult-born hippocampal neurons are more numerous, faster maturing, and more involved in behavior in rats than in mice. J Neurosci (2009) 2.51
New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J Cell Biol (2005) 2.40
Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proc Natl Acad Sci U S A (1999) 2.33
Cognitive reserve and lifestyle. J Clin Exp Neuropsychol (2003) 2.27
Experience dictates stem cell fate in the adult hippocampus. Neuron (2011) 2.18
FGF-2 regulation of neurogenesis in adult hippocampus after brain injury. Proc Natl Acad Sci U S A (2001) 1.90
Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2006) 1.81
Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus (2010) 1.67
Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects. Neuroimage (2003) 1.62
Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus (2009) 1.62
De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance. J Neurosci (2010) 1.56
Neural precursor cells and central nervous system radiation sensitivity. Semin Radiat Oncol (2009) 1.54
Aneuploid neurons are functionally active and integrated into brain circuitry. Proc Natl Acad Sci U S A (2005) 1.53
L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci (2016) 1.51
Surviving hilar somatostatin interneurons enlarge, sprout axons, and form new synapses with granule cells in a mouse model of temporal lobe epilepsy. J Neurosci (2009) 1.49
Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning. Behav Neurosci (2010) 1.38
Reversal of hippocampal neuronal maturation by serotonergic antidepressants. Proc Natl Acad Sci U S A (2010) 1.37
Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci (2007) 1.34
Midlife activity predicts risk of dementia in older male twin pairs. Alzheimers Dement (2008) 1.32
Antidepressant drug-induced stimulation of mouse hippocampal neurogenesis is age-dependent and altered by early life stress. J Comp Neurol (2008) 1.30
13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice. Proc Natl Acad Sci U S A (2004) 1.26
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest (2003) 1.24
Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus. Mol Cell Neurosci (2008) 1.22
Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium. Stem Cells (2008) 1.16
Roles of neural stem cells and adult neurogenesis in adolescent alcohol use disorders. Alcohol (2010) 1.15
The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl) (2007) 1.14
Cranial irradiation alters the behaviorally induced immediate-early gene arc (activity-regulated cytoskeleton-associated protein). Cancer Res (2008) 1.13
The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int J Radiat Oncol Biol Phys (2009) 1.13
Thrombospondin 1--a key astrocyte-derived neurogenic factor. FASEB J (2010) 1.10
Thymidine analog methods for studies of adult neurogenesis are not equally sensitive. J Comp Neurol (2009) 1.06
Genetic influences on exercise-induced adult hippocampal neurogenesis across 12 divergent mouse strains. Genes Brain Behav (2011) 1.05
Adult hippocampal neurogenesis of mammals: evolution and life history. Biol Lett (2009) 1.05
Experimental 'jet lag' inhibits adult neurogenesis and produces long-term cognitive deficits in female hamsters. PLoS One (2010) 1.01
Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis. J Biol Chem (2012) 1.01
Inducible and targeted deletion of the ERK5 MAP kinase in adult neurogenic regions impairs adult neurogenesis in the olfactory bulb and several forms of olfactory behavior. PLoS One (2012) 0.99
Suppression of adult neurogenesis increases the acute effects of kainic acid. Exp Neurol (2014) 0.97
Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation. Hippocampus (2010) 0.96
Anatomical perspectives on adult neural stem cells. J Anat (2005) 0.96
Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior. Transl Psychiatry (2012) 0.96
The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt. Brain Res (2009) 0.96
Modulation of adult-born neurons in the inflamed hippocampus. Front Cell Neurosci (2013) 0.94
Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model. Neuropsychopharmacology (2013) 0.93
Stem-cell-associated structural and functional plasticity in the aging hippocampus. Psychol Aging (2008) 0.93
Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis. Cell Commun Signal (2010) 0.92
Dynamic functions of GABA signaling during granule cell maturation. Front Neural Circuits (2013) 0.92
Neonatal alcohol exposure disrupts hippocampal neurogenesis and contextual fear conditioning in adult rats. Brain Res (2011) 0.92
Birds as a model to study adult neurogenesis: bridging evolutionary, comparative and neuroethological approaches. Eur J Neurosci (2011) 0.90
All in the Family: How the APPs Regulate Neurogenesis. Front Neurosci (2012) 0.90
New striatal neurons in a mouse model of progressive striatal degeneration are generated in both the subventricular zone and the striatal parenchyma. PLoS One (2011) 0.89
Strain differences in proliferation of progenitor cells in the dentate gyrus of the adult rat and the response to fluoxetine are dependent on corticosterone. Neuroscience (2008) 0.87
Is there a role for young hippocampal neurons in adaptation to stress? Behav Brain Res (2011) 0.87
Steroid-induced alterations of mood and behavior in children during treatment for acute lymphoblastic leukemia. Support Care Cancer (2005) 0.86
Neural injury alters proliferation and integration of adult-generated neurons in the dentate gyrus. J Neurosci (2013) 0.86
Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development. J Vet Sci (2011) 0.86
Inhibition of injury-induced cell proliferation in the dentate gyrus of the hippocampus impairs spontaneous cognitive recovery after traumatic brain injury. J Neurotrauma (2015) 0.84
Kv1.1 null mice have enlarged hippocampus and ventral cortex. BMC Neurosci (2007) 0.84
Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. Front Endocrinol (Lausanne) (2012) 0.84
Deficits in adult neurogenesis, contextual fear conditioning, and spatial learning in a Gfap mutant mouse model of Alexander disease. J Neurosci (2013) 0.84
Genetic control of hippocampal neurogenesis. Genome Biol (2006) 0.84
Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Struct Funct (2014) 0.84
Transcript co-variance with Nestin in two mouse genetic reference populations identifies Lef1 as a novel candidate regulator of neural precursor cell proliferation in the adult hippocampus. Front Neurosci (2014) 0.83
Delayed and transient increase of adult hippocampal neurogenesis by physical exercise in DBA/2 mice. PLoS One (2013) 0.83
Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus. Mol Brain (2011) 0.83
No effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse. BMC Neurosci (2009) 0.83
Regulation of adult neurogenesis by behavior and age in the accessory olfactory bulb. Mol Cell Neurosci (2011) 0.83
Disturbed distribution of proliferative brain cells during lupus-like disease. Brain Behav Immun (2009) 0.83
Region-specific expression of mitochondrial complex I genes during murine brain development. PLoS One (2011) 0.82
Potential of Neural Stem Cell-Based Therapy for Parkinson's Disease. Parkinsons Dis (2015) 0.82
Ulinastatin inhibits cerebral ischemia-induced apoptosis in the hippocampus of gerbils. Mol Med Rep (2015) 0.82
Neurotoxicity of cancer chemotherapy. Neural Regen Res (2013) 0.80
Behavioural Effects of Adult Vitamin D Deficiency in BALB/c Mice Are not Associated with Proliferation or Survival of Neurons in the Adult Hippocampus. PLoS One (2016) 0.80
Combining small-volume metabolomic and transcriptomic approaches for assessing brain chemistry. Anal Chem (2013) 0.80
Growth hormone pathways signaling for cell proliferation and survival in hippocampal neural precursors from postnatal mice. BMC Neurosci (2014) 0.80
Resveratrol Enhances Neuroplastic Changes, Including Hippocampal Neurogenesis, and Memory in Balb/C Mice at Six Months of Age. PLoS One (2015) 0.80
Human adult neurogenesis across the ages: An immunohistochemical study. Neuropathol Appl Neurobiol (2016) 0.79
Different regulation of adult hippocampal neurogenesis in Western house mice (Mus musculus domesticus) and C57BL/6 mice. Behav Brain Res (2011) 0.79
Proliferation potential of Müller glia after retinal damage varies between mouse strains. PLoS One (2014) 0.79
Nest of origin predicts adult neuron addition rates in the vocal control system of the zebra finch. Brain Behav Evol (2008) 0.79
Absence of the calcium-binding protein calretinin, not of calbindin D-28k, causes a permanent impairment of murine adult hippocampal neurogenesis. Front Mol Neurosci (2012) 0.78
Comparison of inbred mouse substrains reveals segregation of maladaptive fear phenotypes. Front Behav Neurosci (2014) 0.78
The potential of endogenous neurogenesis for brain repair and regeneration following traumatic brain injury. Neural Regen Res (2014) 0.78
Effects of sex and rearing environment on imipramine response in mice. Psychopharmacology (Berl) (2012) 0.78
Cell proliferation and neuroblast differentiation in the rat dentate gyrus after intrathecal treatment with adipose-derived mesenchymal stem cells. Cell Mol Neurobiol (2011) 0.78
Treadmill Exercise Improves Memory Function Depending on Circadian Rhythm Changes in Mice. Int Neurourol J (2016) 0.77
Microglia-associated granule cell death in the normal adult dentate gyrus. Brain Struct Funct (2009) 0.77
Loss of the mu opioid receptor on different genetic backgrounds leads to increased bromodeoxyuridine labeling in the dentate gyrus only after repeated injection. Neuroscience (2012) 0.77
P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice. Transl Stroke Res (2013) 0.77
Antidepressant and proneurogenic influence of environmental enrichment in mice: protective effects vs recovery. Neuropsychopharmacology (2011) 0.77
Role of Aging and Hippocampus in Time-Place Learning: Link to Episodic-Like Memory? Front Behav Neurosci (2016) 0.77
Genetic control of adult neurogenesis: interplay of differentiation, proliferation and survival modulates new neurons function, and memory circuits. Front Cell Neurosci (2013) 0.77
Exploring Female Mice Interstrain Differences Relevant for Models of Depression. Front Behav Neurosci (2015) 0.76
Tumor suppressive pathways in the control of neurogenesis. Cell Mol Life Sci (2012) 0.76
Increased cell fusion in cerebral cortex may contribute to poststroke regeneration. Stroke Res Treat (2013) 0.76
Effects of treadmill exercise combined with MK 801 treatment on neuroblast differentiation in the dentate gyrus in rats. Cell Mol Neurobiol (2010) 0.76
More hippocampal neurons in adult mice living in an enriched environment. Nature (1997) 10.06
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci (1996) 9.84
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol (1965) 9.18
Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol (1996) 6.23
T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature (1994) 6.20
Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci (1997) 5.78
Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci (1996) 5.53
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci (1992) 4.60
Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J Comp Neurol (1996) 4.42
Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science (1977) 4.34
The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci (1997) 4.07
Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci (1997) 4.00
Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J Neurocytol (1989) 3.92
Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci U S A (1995) 3.89
Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience (1993) 3.84
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61
New stereological methods for counting neurons. Neurobiol Aging (1993) 3.41
Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches. Proc Natl Acad Sci U S A (1997) 3.15
Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience (1994) 3.10
Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain. Proc Natl Acad Sci U S A (1983) 3.05
In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci (1996) 2.72
Isolation, characterization, and use of stem cells from the CNS. Annu Rev Neurosci (1995) 2.52
FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol Cell Neurosci (1995) 2.45
Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature (1996) 2.33
Neurons in the rat dentate gyrus granular layer substantially increase during juvenile and adult life. Science (1982) 2.29
Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex. Development (1996) 2.21
Limits of neurogenesis in primates. Science (1985) 2.19
Adrenal hormones suppress cell division in the adult rat dentate gyrus. J Neurosci (1992) 2.16
Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain. J Neurosci (1992) 2.16
De novo generation of neuronal cells from the adult mouse brain. Proc Natl Acad Sci U S A (1992) 1.97
Seasonal recruitment of hippocampal neurons in adult free-ranging black-capped chickadees. Proc Natl Acad Sci U S A (1994) 1.85
BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone. J Neurocytol (1992) 1.78
Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections. Exp Brain Res (1988) 1.71
Genetic and environmental control of variation in retinal ganglion cell number in mice. J Neurosci (1996) 1.55
Any way you cut it: a new journal policy for the use of unbiased counting methods. J Comp Neurol (1996) 1.28
Blockade of NMDA receptors increases cell death and birth in the developing rat dentate gyrus. J Comp Neurol (1994) 1.26
Recruitment and replacement of hippocampal neurons in young and adult chickadees: an addition to the theory of hippocampal learning. Proc Natl Acad Sci U S A (1996) 1.21
Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey. J Neurosci (1988) 1.18
Evidence that late-generated granule cells do not simply replace earlier formed neurons in the rat dentate gyrus. Exp Brain Res (1986) 1.17
Local homogeneity of cell cycle length in developing mouse cortex. J Neurosci (1997) 1.11
Gene-targeting studies: new methods, old problems. Trends Neurosci (1996) 1.11
Distinct populations of cells in the adult dentate gyrus undergo mitosis or apoptosis in response to adrenalectomy. J Comp Neurol (1996) 1.11
Apoptosis and necrosis induced in different hippocampal neuron populations by repetitive perforant path stimulation in the rat. J Comp Neurol (1996) 1.11
Cell proliferation and cytogenesis in the mouse hippocampus. Adv Anat Embryol Cell Biol (1991) 1.10
Mice, gene targeting and behaviour: more than just genetic background. Trends Neurosci (1996) 1.09
Immunocytochemical detection of 5'-bromodeoxyuridine incorporation in the central nervous system of the mouse. Brain Res Dev Brain Res (1989) 1.07
An allometric study of the area dentata in the rat and mouse. Brain Res (1980) 0.95
The effects of adrenal steroids and excitatory input on neuronal birth and survival. Ann N Y Acad Sci (1994) 0.89
Gonadal and adrenal steroids regulate neurochemical and structural plasticity of the hippocampus via cellular mechanisms involving NMDA receptors. Cell Mol Neurobiol (1996) 0.89
On the sources of strain and sex differences in granule cell number in the dentate area of house mice. Brain Res Dev Brain Res (1989) 0.85
On the development of strain and sex differences in granule cell number in the area dentata of house mice. Brain Res (1988) 0.84
The genetic organization of neuron number in the granule cell layer of the area dentata in house mice. Brain Res (1978) 0.84
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (1996) 28.95
Neurogenesis in the adult human hippocampus. Nat Med (1998) 17.53
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci (1999) 12.50
Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A (2000) 10.88
More hippocampal neurons in adult mice living in an enriched environment. Nature (1997) 10.06
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci (1996) 9.84
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A (1996) 9.15
Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci U S A (1999) 8.83
Vascular niche for adult hippocampal neurogenesis. J Comp Neurol (2000) 7.19
Neural consequences of environmental enrichment. Nat Rev Neurosci (2000) 6.79
A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science (2009) 6.62
Development of a self-inactivating lentivirus vector. J Virol (1998) 6.60
Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci (1997) 4.92
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet (1997) 4.26
The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci (1997) 4.07
Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci U S A (1995) 3.89
Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci (1998) 3.71
Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J Neurosci (1999) 3.61
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61
Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A (1997) 3.40
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J Neurosci (2000) 3.40
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J Virol (1997) 3.37
Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry (2000) 2.87
Regenerating the damaged central nervous system. Nature (2000) 2.85
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience (2004) 2.81
Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. J Neurosci (1988) 2.73
Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature (1998) 2.72
Cell culture. Progenitor cells from human brain after death. Nature (2001) 2.63
Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A (2001) 2.48
FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol Cell Neurosci (1995) 2.45
Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature (1987) 2.33
Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature (1996) 2.33
The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell (1996) 2.26
Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J Neurosci (2000) 2.24
Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain. Neurosci Lett (2000) 2.22
Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci U S A (2010) 2.22
Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles. J Comp Neurol (1999) 2.21
Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J Neurosci (1998) 2.17
Can stem cells cross lineage boundaries? Nat Med (2001) 2.08
Neuronal differentiation and morphological integration of hippocampal progenitor cells transplanted to the retina of immature and mature dystrophic rats. Mol Cell Neurosci (2000) 2.07
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J Neurosci (1997) 2.07
Proliferation, differentiation, and long-term culture of primary hippocampal neurons. Proc Natl Acad Sci U S A (1993) 2.00
Transcriptional profiling reveals strict boundaries between hippocampal subregions. J Comp Neurol (2001) 1.98
Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol (1999) 1.79
Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proc Natl Acad Sci U S A (1986) 1.77
Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development (1999) 1.73
Essential role of neocortical acetylcholine in spatial memory. Nature (1995) 1.68
Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci (2002) 1.67
Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer. J Virol (1999) 1.64
Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina. Mol Cell Neurosci (1998) 1.62
Spatial learning and motor deficits in aged rats. Neurobiol Aging (1984) 1.60
An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron (1998) 1.58
Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. Proc Natl Acad Sci U S A (1999) 1.54
Hippocampal connections and spatial discrimination. Brain Res (1978) 1.54
Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus. Curr Biol (1998) 1.51
FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron (2000) 1.50
A packaging cell line for lentivirus vectors. J Virol (1999) 1.48
New nerve cells for the adult brain. Sci Am (1999) 1.47
Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression. J Cell Biol (2001) 1.42
Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (1988) 1.42
Nicotinic receptor-induced apoptotic cell death of hippocampal progenitor cells. J Neurosci (1998) 1.42
Alzheimer's disease and spirochetes; a questionable relationship. Neuroreport (1993) 1.41
Lentiviral vectors: regulated gene expression. Mol Ther (2000) 1.39
Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev (2001) 1.35
Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc Natl Acad Sci U S A (1996) 1.35
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis (2010) 1.35
Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc Natl Acad Sci U S A (1994) 1.34
Activity-dependent regulation of neuronal plasticity and self repair. Prog Brain Res (2000) 1.29
Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Exp Neurol (1996) 1.26
FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord. Exp Neurol (1997) 1.23
Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Exp Neurol (1999) 1.23
Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus (1999) 1.22
Neurogenesis in the adult hippocampus. Novartis Found Symp (2000) 1.18
Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. J Neurosci (1990) 1.17
Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiol Aging (1992) 1.17
Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp Neurol (1994) 1.15
Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proc Natl Acad Sci U S A (1999) 1.14
Modeling psychiatric disorders at the cellular and network levels. Mol Psychiatry (2012) 1.14
Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res (1991) 1.11
An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model. Gene Ther (2004) 1.10
Human amnion membrane serves as a substratum for growing axons in vitro and in vivo. Science (1987) 1.10
Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats. J Neurosci (1984) 1.10
Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing postdamage age. J Neurosci (1994) 1.09
Synaptic loss in cognitively impaired aged rats is ameliorated by chronic human nerve growth factor infusion. Neuroscience (1995) 1.07
NGF improves spatial memory in aged rodents as a function of age. J Neurosci (1991) 1.06
Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path. Neurol Res (1985) 1.06
Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Ther (1996) 1.05
Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat. Exp Neurol (1991) 1.04
Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration. J Neurosci (1995) 1.04
Grafting genetically modified cells into the rat brain: characteristics of E. coli beta-galactosidase as a reporter gene. Brain Res Mol Brain Res (1989) 1.03
Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor. Neuron (1991) 1.02
Petit mal epilepsy and parkinsonian tremor: hypothesis of a common pacemaker. Neuroscience (1990) 1.02
NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat. Neuron (1989) 1.02
Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology. J Neurosci (2004) 1.02
Spinal cord neuroblasts proliferate in response to basic fibroblast growth factor. J Neurosci (1994) 1.02
Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol (1991) 1.02