Published in Genes Dev on September 01, 1993
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J (1996) 4.58
Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49
DNA strand annealing is promoted by the yeast Rad52 protein. Proc Natl Acad Sci U S A (1996) 4.42
Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci U S A (2001) 4.42
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res (1996) 4.37
Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics (1996) 4.33
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res (2008) 4.06
Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc Natl Acad Sci U S A (1995) 3.79
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.57
Molecular interaction map of the mammalian cell cycle control and DNA repair systems. Mol Biol Cell (1999) 3.41
Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol (1995) 2.96
RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.90
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev (1998) 2.77
Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol (1997) 2.65
Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity. Genetics (1995) 2.33
Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31
The consequences of Rad51 overexpression for normal and tumor cells. DNA Repair (Amst) (2008) 2.30
Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol Cell Biol (1996) 2.21
A novel allele of Saccharomyces cerevisiae RFA1 that is deficient in recombination and repair and suppressible by RAD52. Mol Cell Biol (1995) 2.21
Use of a chromosomal inverted repeat to demonstrate that the RAD51 and RAD52 genes of Saccharomyces cerevisiae have different roles in mitotic recombination. Genetics (1994) 2.15
Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination. Genetics (1994) 2.02
Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis. Proc Natl Acad Sci U S A (2001) 1.97
The role of DNA repair genes in recombination between repeated sequences in yeast. Genetics (1995) 1.87
Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. Proc Natl Acad Sci U S A (1996) 1.74
Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA. Mol Cell Biol (1998) 1.74
Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing. Mol Cell Biol (2006) 1.71
Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res (1998) 1.70
The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing. Genetics (2001) 1.69
Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination. Proc Natl Acad Sci U S A (2002) 1.68
Expression of Arabidopsis CAX1 in tobacco: altered calcium homeostasis and increased stress sensitivity. Plant Cell (1999) 1.61
The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae. PLoS Genet (2006) 1.57
Interaction of human recombination proteins Rad51 and Rad54. Nucleic Acids Res (1997) 1.54
Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51-DNA complexes. EMBO J (2002) 1.54
Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background. Mol Cell Biol (1999) 1.53
Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics (1996) 1.52
The essential functions of human Rad51 are independent of ATP hydrolysis. Mol Cell Biol (1999) 1.51
Rad51 expression and localization in B cells carrying out class switch recombination. Proc Natl Acad Sci U S A (1996) 1.50
Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms. EMBO J (2000) 1.49
Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase. Mol Cell Biol (1996) 1.45
Choreography of recombination proteins during the DNA damage response. DNA Repair (Amst) (2009) 1.40
Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51. Genetics (1995) 1.38
A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA. Genetics (1999) 1.37
DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae. Genetics (1998) 1.35
Coordinated response of mammalian Rad51 and Rad52 to DNA damage. EMBO Rep (2000) 1.35
Sequestration of mammalian Rad51-recombination protein into micronuclei. J Cell Biol (1999) 1.33
A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52. Genetics (2002) 1.32
Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo. J Cell Biol (2009) 1.29
Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae. Genetics (2014) 1.27
A novel allele of RAD52 that causes severe DNA repair and recombination deficiencies only in the absence of RAD51 or RAD59. Genetics (1999) 1.26
Molecular dissection of interactions between Rad51 and members of the recombination-repair group. Mol Cell Biol (2001) 1.24
Rad51 protein controls Rad52-mediated DNA annealing. J Biol Chem (2008) 1.23
Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52. J Biol Chem (2008) 1.18
Characterization of strand exchange activity of yeast Rad51 protein. Mol Cell Biol (1997) 1.16
Saccharomyces cerevisiae RAD52 alleles temperature-sensitive for the repair of DNA double-strand breaks. Genetics (1994) 1.16
Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity. J Biol Chem (2008) 1.15
Specificities of the Saccharomyces cerevisiae rad6, rad18, and rad52 mutators exhibit different degrees of dependence on the REV3 gene product, a putative nonessential DNA polymerase. Genetics (1995) 1.15
Rad52 SUMOylation affects the efficiency of the DNA repair. Nucleic Acids Res (2010) 1.14
A core activity associated with the N terminus of the yeast RAD52 protein is revealed by RAD51 overexpression suppression of C-terminal rad52 truncation alleles. Genetics (1999) 1.14
Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement. Clin Cancer Res (2012) 1.11
Molecular evolution of a sex determination protein. FEM-2 (pp2c) in Caenorhabditis. Genetics (1998) 1.09
Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediator and the Srs2 anti-recombinase. J Biol Chem (2009) 1.02
Multiple start codons and phosphorylation result in discrete Rad52 protein species. Nucleic Acids Res (2006) 1.00
Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination. J Biol Chem (2009) 0.96
Identification of plant RAD52 homologs and characterization of the Arabidopsis thaliana RAD52-like genes. Plant Cell (2011) 0.94
Genome wide distribution of illegitimate recombination events in Kluyveromyces lactis. Nucleic Acids Res (2006) 0.94
Presynaptic filament dynamics in homologous recombination and DNA repair. Crit Rev Biochem Mol Biol (2011) 0.93
The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae. Genetics (2003) 0.92
Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52. Nucleic Acids Res (2005) 0.89
Rsp5, a ubiquitin-protein ligase, is involved in degradation of the single-stranded-DNA binding protein rfa1 in Saccharomyces cerevisiae. Mol Cell Biol (2000) 0.87
Selection on meiosis genes in diploid and tetraploid Arabidopsis arenosa. Mol Biol Evol (2014) 0.87
Cells expressing murine RAD52 splice variants favor sister chromatid repair. Mol Cell Biol (2006) 0.86
Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae. PLoS One (2010) 0.86
Mutational analysis of Brh2 reveals requirements for compensating mediator functions. Mol Microbiol (2010) 0.84
Enhancement of gene targeting in human cells by intranuclear permeation of the Saccharomyces cerevisiae Rad52 protein. Nucleic Acids Res (2010) 0.82
Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity. Bioessays (2014) 0.82
Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex. J Proteome Res (2009) 0.81
Investigation of the stability of yeast rad52 mutant proteins uncovers post-translational and transcriptional regulation of Rad52p. Genetics (2003) 0.81
Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination. Genes (Basel) (2016) 0.80
Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds. Br J Cancer (1999) 0.79
Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells. Eukaryot Cell (2010) 0.79
Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregation. BMC Biochem (2009) 0.79
An archaeal RadA paralog influences presynaptic filament formation. DNA Repair (Amst) (2013) 0.79
Rad52 multimerization is important for its nuclear localization in Saccharomyces cerevisiae. DNA Repair (Amst) (2007) 0.78
A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101. Mol Biol Cell (2013) 0.77
Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing. J Biol Chem (2014) 0.76
Yeast cell-free system that catalyses joint-molecule formation in a Rad51p- and Rad52p-dependent fashion. Biochem J (2000) 0.76
Cell biology of mitotic recombination. Cold Spring Harb Perspect Biol (2015) 0.76
Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing. PLoS One (2016) 0.76
A protein phosphatase 2C gene, LjNPP2C1, from Lotus japonicus induced during root nodule development. Proc Natl Acad Sci U S A (1999) 0.76
Expression of the E.coli ada gene in S.cerevisiae provides cellular resistance to N-methyl-N'-nitro-N-nitrosoguanidine in rad6 but not in rad52 mutants. Nucleic Acids Res (1994) 0.75
Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair. Nucleic Acids Res (2016) 0.75
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci U S A (1997) 4.13
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Immunity (1998) 3.58
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.57
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature (2000) 3.48
Chromosomal double-strand break repair in Ku80-deficient cells. Proc Natl Acad Sci U S A (1996) 2.91
A link between double-strand break-related repair and V(D)J recombination: the scid mutation. Proc Natl Acad Sci U S A (1991) 2.68
Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucleic Acids Res (1997) 2.58
Residual intrascleral and intraretinal melanoma: a concern with lamellar sclerouvectomy for uveal melanoma. Am J Ophthalmol (1991) 2.28
Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair. Genes Dev (1994) 2.18
The effect of needle gauge on recirculation, venous pressure and bleeding from puncture sites. Clin Nephrol (1995) 2.01
The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells. Mol Cell Biol (1993) 2.01
The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in vivo. J Mol Biol (1984) 1.90
Isolation and characterization of the human MRE11 homologue. Genomics (1995) 1.83
Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha. J Biol Chem (1982) 1.76
The termination region for SV40 DNA replication directs the mode of separation for the two sibling molecules. Cell (1985) 1.69
The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement. Genes Dev (1988) 1.61
scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase. Mol Cell Biol (1995) 1.49
DNA ligase I mediates essential functions in mammalian cells. Mol Cell Biol (1995) 1.47
Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51. Genetics (1995) 1.38
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit. J Biol Chem (1997) 1.29
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions. EMBO J (1997) 1.28
Wild-type V(D)J recombination in scid pre-B cells. Mol Cell Biol (1990) 1.19
V(D)J recombination coding junction formation without DNA homology: processing of coding termini. Mol Cell Biol (1993) 1.13
Strand breaks without DNA rearrangement in V (D)J recombination. Mol Cell Biol (1991) 1.04
A wild-type DNA ligase I gene is expressed in Bloom's syndrome cells. Proc Natl Acad Sci U S A (1991) 1.04
Coding sequence composition flanking either signal element alters V(D)J recombination efficiency. Nucleic Acids Res (1995) 1.03
Independence of R/M/N focus formation and the presence of intact BRCA1. Science (2000) 1.02
DNA polymerase alpha cofactors C1C2 function as primer recognition proteins. J Biol Chem (1983) 1.01
Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Curr Biol (2001) 1.01
Normal V(D)J coding junction formation in DNA ligase I deficiency syndromes. J Immunol (1994) 1.00
Functions of the DNA dependent protein kinase. Cancer Surv (1997) 1.00
Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase. Carcinogenesis (1998) 0.94
scid cells efficiently integrate hairpin and linear DNA substrates. Mol Cell Biol (1994) 0.88
Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8. Mutat Res (1994) 0.87
PDR in juvenile onset diabetics: high-risk proliferative diabetic retinopathy in juvenile onset diabetics. Retina (1981) 0.87
Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation. Oncogene (1998) 0.86
Cell cycle checkpoints and repair of ionizing radiation damage. Stem Cells (1995) 0.85
V(D)J recombination. From RAGs to stitches. Nature (1997) 0.83
Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1. Cold Spring Harb Symp Quant Biol (2000) 0.79
Persistence of DNA synthesis arrest sites in the presence of T4 DNA polymerase and T4 gene 32, 44, 45 and 62 DNA polymerase accessory proteins. Nucleic Acids Res (1986) 0.77
Intraocular antiviral penetration. Arch Ophthalmol (1983) 0.75