Published in Clin Chem on September 01, 1993
Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke (2005) 1.91
Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. Arch Intern Med (2009) 1.83
Hyperhomocysteinaemia and premature coronary artery disease in the Chinese. Heart (1996) 1.39
Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction. Proc Natl Acad Sci U S A (2001) 1.34
Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study. J Clin Invest (1996) 1.09
Homocysteine, system b0,+ and the renal epithelial transport and toxicity of inorganic mercury. Am J Pathol (2004) 1.00
Serum folate, vitamin B-12, and homocysteine and their association with depressive symptoms among U.S. adults. Psychosom Med (2010) 1.00
Association between serum homocysteine and arterial stiffness in elderly: a community-based study. J Geriatr Cardiol (2014) 1.00
ACP Broadsheet No 152: March 1998. Clinical implications of plasma homocysteine measurement in cardiovascular disease. J Clin Pathol (1998) 0.99
Homocysteine stimulates the expression of monocyte chemoattractant protein-1 receptor (CCR2) in human monocytes: possible involvement of oxygen free radicals. Biochem J (2001) 0.96
Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route. Br J Clin Pharmacol (2003) 0.96
Study of serum homocysteine, folic Acid and vitamin b(12) in patients with preeclampsia. Indian J Clin Biochem (2011) 0.96
Hyperhomocysteinemia: a new risk factor for central retinal vein occlusion. Trans Am Ophthalmol Soc (2000) 0.94
Folate and vitamin B12 status of adolescent girls in northern Nigeria. J Natl Med Assoc (2000) 0.92
Effects of pre-analytical processes on blood samples used in metabolomics studies. Anal Bioanal Chem (2015) 0.91
Cobalamin and folate status in 6 to 35 months old children presenting with acute diarrhea in Bhaktapur, Nepal. PLoS One (2014) 0.90
Simple, Fast, and Simultaneous Detection of Plasma Total Homocysteine, Methylmalonic Acid, Methionine, and 2-Methylcitric Acid Using Liquid Chromatography and Mass Spectrometry (LC/MS/MS). JIMD Rep (2013) 0.85
Assessment of homocysteine status. J Inherit Metab Dis (1997) 0.85
Lowering homocysteine and modifying nutritional status with folic acid and vitamin B(12) in Indian patients of vascular disease. J Clin Biochem Nutr (2012) 0.85
Effect of enalapril on plasma homocysteine levels in patients with essential hypertension. J Zhejiang Univ Sci B (2010) 0.83
Plasma homocysteine levels in noninsulin-dependent diabetes mellitus with retinopathy and neovascular glaucoma. Int Ophthalmol (2005) 0.83
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency. Front Mol Biosci (2016) 0.83
Hyperhomocysteinemia, as an independent risk factor for retinal venous occlusion in an Indian population. Indian J Clin Biochem (2012) 0.82
Homocysteine status and acute myocardial infarction among Tamilians. Indian J Clin Biochem (2005) 0.81
Homocysteine and carotid plaque stability: a cross-sectional study in Chinese adults. PLoS One (2014) 0.80
Changes in predictors and status of homocysteine in young male adults after a dietary intervention with vegetables, fruits and bread. Eur J Nutr (2008) 0.80
Measurement and use of total plasma homocysteine. American Society of Human Genetics/American College of Medical Genetics Test and Transfer Committee Working Group. Am J Hum Genet (1998) 0.80
Reference interval determination of total plasma homocysteine in an Indian population. Indian J Clin Biochem (2013) 0.78
Clinical Implications of Methylenetetrahydrofolate Reductase Mutations and Plasma Homocysteine Levels in Patients with Thromboembolic Occlusion. Vasc Specialist Int (2014) 0.78
Low-dose B vitamins supplementation ameliorates cardiovascular risk: a double-blind randomized controlled trial in healthy Chinese elderly. Eur J Nutr (2014) 0.78
Relationship of plasma homocysteine with lipid profile parameters in ischemic heart disease. Indian J Clin Biochem (2006) 0.78
Autonomic cardiovascular responses in acclimatized lowlanders on prolonged stay at high altitude: a longitudinal follow up study. PLoS One (2014) 0.78
Determinants and distributions of plasma total homocysteine concentrations among school children in Taiwan. Eur J Epidemiol (2003) 0.78
Three different presentation of same pathophysiology. Acta Inform Med (2012) 0.78
Prenatal diagnosis using genetic sequencing and identification of a novel mutation in MMACHC. BMC Med Genet (2015) 0.78
The association of homocysteine with metabolic syndrome in a community-dwelling population: homocysteine might be concomitant with metabolic syndrome. PLoS One (2014) 0.77
Evaluation of enteral formulas for nutrition, health, and quality of life among stroke patients. Nutr Res Pract (2010) 0.76
Plasma Total Homocysteine Levels are not Associated with Medial Temporal Lobe Atrophy, but with White Matter Changes in Alzheimer's Disease. J Clin Neurol (2009) 0.76
Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients. Croat Med J (2013) 0.76
The relation of plasma homocysteine to radiographic knee osteoarthritis. Osteoarthritis Cartilage (2008) 0.76
Transient increase in homocysteine but not hyperhomocysteinemia during acute exercise at different intensities in sedentary individuals. PLoS One (2012) 0.76
Sarcopenic obesity and cognitive functioning: the mediating roles of insulin resistance and inflammation? Curr Gerontol Geriatr Res (2012) 0.76
A Study of the Relationships between Serum Calcitonin Gene-Related Peptide, Sex Hormone, Homocysteine and Coronary Heart Disease in Postmenopausal Women. Int J Biomed Sci (2006) 0.75
A magnetic nanoparticles-based method for DNA extraction from the saliva of stroke patients. Neural Regen Res (2013) 0.75
Serum levels of homocysteine in mice with malignant tumours. Exp Clin Cardiol (2003) 0.75
The Effects of Muscle Mass on Homocyst(e)ine Levels in Plasma and Urine. Int J Exerc Sci (2012) 0.75
Homocysteine, vitamins, and coronary artery disease. Comprehensive review of the literature. Can Fam Physician (2000) 0.75
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents. FASEB J (2016) 0.75
Fruit and vegetables consumption is associated with higher vitamin intake and blood vitamin status among European adolescents. Eur J Clin Nutr (2017) 0.75
Current perspectives on laboratory markers for the assessment of cardiovascular disease and myocardial damage. Indian J Clin Biochem (1999) 0.75
Hyperhomocysteinemia, a biochemical tool for differentiating ischemic and nonischemic central retinal vein occlusion during the early acute phase. Korean J Ophthalmol (2015) 0.75
Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring. J Nutr Metab (2017) 0.75
Compliance to the recommended use of folic acid supplements for women in Sweden is higher among those under treatment for infertility than among fertile controls and is also related to socioeconomic status and lifestyle. Food Nutr Res (2017) 0.75
No association between elevated homocysteine levels and carotid atherosclerosis in a rural population in China. Stroke Vasc Neurol (2016) 0.75
Homocysteine inhibits angiogenesis through cytoskeleton remodeling. Biosci Rep (2017) 0.75
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature (2001) 6.95
Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men. Lancet (2000) 5.61
Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid. Biochemistry (1972) 5.49
Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med (1997) 5.35
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol (1998) 4.48
Lack of effect of acid suppression therapy on gastric atrophy. Nordic Gerd Study Group. Gastroenterology (1999) 4.41
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med (1988) 4.22
A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA (1992) 3.96
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia. Proc Natl Acad Sci U S A (1995) 3.51
Clinical spectrum and diagnosis of cobalamin deficiency. Blood (1990) 3.29
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest (2001) 3.24
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation (1997) 3.23
High prevalence of cobalamin deficiency in elderly outpatients. J Am Geriatr Soc (1992) 3.12
Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr (1994) 3.08
Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. Am J Med (1994) 2.98
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study. Diabetologia (2007) 2.96
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol (2005) 2.96
Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study. Circulation (1998) 2.88
A transcriptional roadmap to wood formation. Proc Natl Acad Sci U S A (2001) 2.85
Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study. Am J Clin Nutr (2000) 2.53
Transplantation of porcine fetal pancreas to diabetic patients. Lancet (1994) 2.52
Isolation and characterization of the transferrin receptor from human placenta. J Biol Chem (1979) 2.48
The controversy over homocysteine and cardiovascular risk. Am J Clin Nutr (2000) 2.45
Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study. Am J Clin Nutr (1998) 2.41
Experimental studies on cholera immunization. II. Evidence for protective antitoxic immunity mediated by serum antibodies as well as local antibodies. Infect Immun (1972) 2.37
Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet (1995) 2.36
Enzymatic conjugation of epoxides with glutathione. J Biol Chem (1973) 2.34
Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. JAMA (1995) 2.31
Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group. Circulation (1998) 2.31
Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia. J Clin Invest (1996) 2.30
Effective treatment of cobalamin deficiency with oral cobalamin. Blood (1998) 2.29
Elevated methylmalonic acid and total homocysteine levels show high prevalence of vitamin B12 deficiency after gastric surgery. Ann Intern Med (1996) 2.19
Biological and clinical implications of the MTHFR C677T polymorphism. Trends Pharmacol Sci (2001) 2.13
Homocysteine and other thiols in plasma and urine: automated determination and sample stability. Clin Chem (1993) 2.07
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation (1996) 2.06
Primary carcinoma of the duodenum. Ann Surg (1980) 2.04
Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Annu Rev Nutr (1992) 2.03
Wild-type Escherichia coli cells regulate the membrane lipid composition in a "window" between gel and non-lamellar structures. J Biol Chem (1996) 1.98
Metabolic evidence that deficiencies of vitamin B-12 (cobalamin), folate, and vitamin B-6 occur commonly in elderly people. Am J Clin Nutr (1993) 1.98
The effect of a subnormal vitamin B-6 status on homocysteine metabolism. J Clin Invest (1996) 1.91
Diagnosis of cobalamin deficiency I: usefulness of serum methylmalonic acid and total homocysteine concentrations. Am J Hematol (1990) 1.87
Use of genetically marked minicells as a probe in measurement of predation on bacteria in aquatic environments. Appl Environ Microbiol (1986) 1.87
Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy. J Lab Clin Med (1989) 1.85
Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency. FASEB J (1993) 1.85
Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine Study. Am J Clin Nutr (2001) 1.84
Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry. J Clin Invest (1988) 1.80
Elevation of serum cystathionine levels in patients with cobalamin and folate deficiency. Blood (1993) 1.80
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet (1995) 1.79
Serum total homocysteine and coronary heart disease. Int J Epidemiol (1995) 1.79
Plasma homocysteine in the acute and convalescent phases after stroke. Stroke (1995) 1.78
Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med (1995) 1.77
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A (1994) 1.76
Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations. Am J Hematol (1990) 1.71
Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes (2001) 1.71
Isolated mouse pancreatic islets in culture: effects of serum and different culture media on the insulin production of the islets. Diabetologia (1978) 1.67
Vitamin B12 and folate deficiency in later life. Age Ageing (2004) 1.67
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. Metabolism (1993) 1.66
Desaturation and elongation of Fatty acids and insulin action. Ann N Y Acad Sci (2002) 1.64
Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids. J Clin Invest (1997) 1.63
Elevation of 2-methylcitric acid I and II levels in serum, urine, and cerebrospinal fluid of patients with cobalamin deficiency. Metabolism (1993) 1.62
Cobalamin analogues are present in human plasma and can mask cobalamin deficiency because current radioisotope dilution assays are not specific for true cobalamin. N Engl J Med (1978) 1.62
Molecular cloning of L-methylmalonyl-CoA mutase: gene transfer and analysis of mut cell lines. Proc Natl Acad Sci U S A (1988) 1.61
Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area. Stroke (1999) 1.59
Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study. Am J Clin Nutr (1997) 1.58
Activation of old carbon by erosion of coastal and subsea permafrost in Arctic Siberia. Nature (2012) 1.55
Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium. Acta Radiol (2001) 1.55
Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry (2000) 1.53
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use. Am J Clin Nutr (2001) 1.53
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. Circ Res (2001) 1.50
A common methylenetetrahydrofolate reductase gene mutation and longevity. Atherosclerosis (1998) 1.50
The plasma lipids, lipoproteins, and diet of the Tarahumara indians of Mexico. Am J Clin Nutr (1978) 1.49
Racial differences in prevalence of cobalamin and folate deficiencies in disabled elderly women. Am J Clin Nutr (1999) 1.48
Efficacy and safety of cholestyramine therapy in peripubertal and prepubertal children with familial hypercholesterolemia. J Pediatr (1996) 1.47
Binding and uptake of transcobalamin II by human fibroblasts. J Clin Invest (1978) 1.46
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study. QJM (2006) 1.46
Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets. Endocrinology (1987) 1.45
Glycine N -methyltransferase deficiency: a new patient with a novel mutation. J Inherit Metab Dis (2003) 1.44
Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patients. Clin Pharmacol Ther (2007) 1.43
Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia. J Inherit Metab Dis (2001) 1.42
Primary carcinoma of the appendix. Ann Surg (1976) 1.41
Recognition of two intracellular cobalamin binding proteins and their identification as methylmalonyl-CoA mutase and methionine synthetase. Proc Natl Acad Sci U S A (1977) 1.40
Vitamin B-12 deficiency in the elderly: current dilemmas. Am J Clin Nutr (1997) 1.40
Vitamin B12 status and rate of brain volume loss in community-dwelling elderly. Neurology (2008) 1.39
Regression of atherosclerosis in humans: fact or myth? Circulation (1981) 1.38
Isolation and characterization of methylmalonyl-CoA mutase from human placenta. J Biol Chem (1980) 1.38
Contributions of a transient outward current to repolarization in human atrium. Am J Physiol (1989) 1.36