Published in Metabolism on November 01, 1993
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The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway. Nutrients (2013) 1.04
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A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab (2010) 1.00
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An indirect response model of homocysteine suppression by betaine: optimising the dosage regimen of betaine in homocystinuria. Br J Clin Pharmacol (2002) 0.82
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Enzyme replacement with PEGylated cystathionine β-synthase ameliorates homocystinuria in murine model. J Clin Invest (2016) 0.81
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med (2009) 0.81
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High homocysteine induces betaine depletion. Biosci Rep (2015) 0.80
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Regulation of vascular endothelial growth factor by metabolic context of the cell. Glycoconj J (2014) 0.78
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Maternal methionine adenosyltransferase I/III deficiency: reproductive outcomes in a woman with four pregnancies. J Inherit Metab Dis (2003) 0.76
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Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia. Metabolism (2007) 0.76
Nuclear magnetic resonance-based serum metabolic profiling of dairy cows with footrot. J Vet Med Sci (2016) 0.75
Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy. Nutrients (2016) 0.75
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature (2001) 6.95
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med (1988) 4.22
Clinical spectrum and diagnosis of cobalamin deficiency. Blood (1990) 3.29
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Effective treatment of cobalamin deficiency with oral cobalamin. Blood (1998) 2.29
Elevated methylmalonic acid and total homocysteine levels show high prevalence of vitamin B12 deficiency after gastric surgery. Ann Intern Med (1996) 2.19
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Metabolic evidence that deficiencies of vitamin B-12 (cobalamin), folate, and vitamin B-6 occur commonly in elderly people. Am J Clin Nutr (1993) 1.98
The effect of a subnormal vitamin B-6 status on homocysteine metabolism. J Clin Invest (1996) 1.91
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Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency. FASEB J (1993) 1.85
Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry. J Clin Invest (1988) 1.80
Elevation of serum cystathionine levels in patients with cobalamin and folate deficiency. Blood (1993) 1.80
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet (1995) 1.79
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Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe. Br J Haematol (1994) 1.78
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Digoxin-inactivating bacteria: identification in human gut flora. Science (1983) 1.68
Elevation of 2-methylcitric acid I and II levels in serum, urine, and cerebrospinal fluid of patients with cobalamin deficiency. Metabolism (1993) 1.62
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Vitamin B-12 deficiency in the elderly: current dilemmas. Am J Clin Nutr (1997) 1.40
Hematologic effects of alcohol in man in the absence of nutritional deficiency. N Engl J Med (1969) 1.37
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate. Am J Epidemiol (1996) 1.34
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Hypoglycemia in children with acute diarrhoea. Lancet (1966) 1.22
The mitogenic effect of the lymphocytosis promoting factor from Bordetella pertussis on human lymphocytes. J Clin Invest (1977) 1.16
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Pancytopenia in Zimbabwe. Am J Med Sci (1999) 1.05
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Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry. J Clin Invest (1986) 1.05
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High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest (2006) 0.94
Vitamin B12 deficiency in African American and white octogenarians and centenarians in Georgia. J Nutr Health Aging (2010) 0.94
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Apparent ruminal synthesis and intestinal disappearance of vitamin B12 and its analogs in dairy cows. J Dairy Sci (2009) 0.91
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Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord. Exp Neurol (1997) 0.90
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