Published in EXS on January 01, 1993
The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J Cell Biol (1995) 2.67
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. Mol Cell Biol (1997) 2.43
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc Natl Acad Sci U S A (1994) 2.36
The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol (1999) 1.67
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. Proc Natl Acad Sci U S A (1996) 1.58
Tyrosine residues 654 and 670 in beta-catenin are crucial in regulation of Met-beta-catenin interactions. Exp Cell Res (2006) 1.37
Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism. Mol Biol Cell (1996) 1.35
Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors. J Clin Invest (1996) 1.27
Hepatocyte growth factor and basic fibroblast growth factor regulate atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease via the mitogen-activated protein kinase signaling pathway. Exp Ther Med (2013) 0.79
Induction of p53-dependent p21 limits proliferative activity of rat hepatocytes in the presence of hepatocyte growth factor. PLoS One (2013) 0.79
Alterative expression of the collagenase and adhesion molecules in the highly metastatic clones of human colonic cancer cell lines. Clin Exp Metastasis (1998) 0.75
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell (1995) 11.86
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science (1998) 10.53
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science (1997) 8.81
Transformation of mammalian cells by constitutively active MAP kinase kinase. Science (1994) 8.69
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (1991) 8.68
Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions. Proc Natl Acad Sci U S A (1980) 7.77
PI3K: downstream AKTion blocks apoptosis. Cell (1997) 7.73
Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol (2001) 7.20
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature (1985) 7.10
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell (1987) 5.87
Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85
Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus. Science (1980) 5.30
Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene (1979) 5.09
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell (1989) 4.86
Abnormal centrosome amplification in the absence of p53. Science (1996) 4.60
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature (1991) 4.44
Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes. Nature (1988) 4.24
Mechanism of met oncogene activation. Cell (1986) 4.20
The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs. Nature (1989) 4.13
Construction of a general human chromosome jumping library, with application to cystic fibrosis. Science (1987) 3.87
Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med (2001) 3.64
Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc Natl Acad Sci U S A (1988) 3.52
Cloning of herpes simplex type 1 DNA fragments in a bacteriophage lambda vector. Science (1979) 3.47
The human met oncogene is related to the tyrosine kinase oncogenes. Nature (1985) 3.46
Biological activity of cloned Moloney sarcoma virus DNA: Terminally redundant sequences may enhance transformation efficiency. Proc Natl Acad Sci U S A (1980) 3.29
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine. Mol Cell Biol (1991) 3.20
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc Natl Acad Sci U S A (1997) 3.19
Structures of two spliced herpes simplex virus type 1 immediate-early mRNA's which map at the junctions of the unique and reiterated regions of the virus DNA S component. J Virol (1981) 3.19
Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1982) 3.14
An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science (2000) 3.12
Genomic instability and apoptosis are frequent in p53 deficient young mice. Oncogene (1997) 3.01
Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda. Proc Natl Acad Sci U S A (1979) 2.98
Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci U S A (1997) 2.92
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Mol Cell Biol (1993) 2.87
Scatter factor induces blood vessel formation in vivo. Proc Natl Acad Sci U S A (1993) 2.86
Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. Proc Natl Acad Sci U S A (2000) 2.80
Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex. Mol Cell Biol (1990) 2.71
Interleukin 3-dependent survival by the Akt protein kinase. Proc Natl Acad Sci U S A (1997) 2.64
Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Natl Acad Sci U S A (1986) 2.62
The product of the mos proto-oncogene as a candidate "initiator" for oocyte maturation. Science (1989) 2.58
BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science (1999) 2.54
Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol (1992) 2.53
Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene (2000) 2.52
DNA sequence of an immediate-early gene (IEmRNA-5) of herpes simplex virus type I. Nucleic Acids Res (1982) 2.50
Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs. Nature (1989) 2.47
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell (1991) 2.46
Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron (1994) 2.44
Structure of varicella-zoster virus DNA. J Virol (1981) 2.43
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. Mol Cell Biol (1997) 2.43
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc Natl Acad Sci U S A (1994) 2.36
c-mos proto-oncogene RNA transcripts in mouse tissues: structural features, developmental regulation, and localization in specific cell types. Mol Cell Biol (1987) 2.35
A novel germ line juxtamembrane Met mutation in human gastric cancer. Oncogene (2000) 2.35
Met and hepatocyte growth factor/scatter factor expression in human gliomas. Cancer Res (1997) 2.30
Platelet alpha granules contain a growth factor for fibroblasts. Blood (1979) 2.18
The met proto-oncogene receptor and lumen formation. Science (1992) 2.08
Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network. Mol Cell Biol (1996) 2.05
Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron (1991) 2.03
AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation. Mol Cell Biol (1995) 2.03
Meiotic initiation by the mos protein in Xenopus. Nature (1992) 2.00
Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron (1992) 1.96
The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron (2000) 1.95
New method for detecting cellular transforming genes. Science (1982) 1.92
Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis. J Mol Med (Berl) (1996) 1.91
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity. Oncogene (2001) 1.82
Sodium dodecylsulfate-dependent anomalies in gel electrophoresis: alterations in the banding patterns of foot-and-mouth disease virus polypeptides. Anal Biochem (1974) 1.81
Expression of c-mos proto-oncogene transcripts in mouse tissues. Nature (1985) 1.78
The Met proto-oncogene mesenchymal to epithelial cell conversion. Science (1994) 1.77
The mutationally activated Met receptor mediates motility and metastasis. Proc Natl Acad Sci U S A (1998) 1.76
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding. J Biol Chem (1997) 1.75
Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma. J Biol Chem (1996) 1.66
Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases. Proc Natl Acad Sci U S A (1988) 1.64
Three additional DNA polymorphisms in the met gene and D7S8 locus: use in prenatal diagnosis of cystic fibrosis. J Pediatr (1987) 1.63
Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc Natl Acad Sci U S A (1998) 1.63
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells. Mol Cell Biol (1999) 1.62
Evidence that MIG-6 is a tumor-suppressor gene. Oncogene (2006) 1.62
Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene. Cell Growth Differ (1990) 1.62
The ras oncogene-mediated sensitization of human cells to topoisomerase II inhibitor-induced apoptosis. J Natl Cancer Inst (1999) 1.61
Molecular cloning and physical mapping of varicella-zoster virus DNA. Proc Natl Acad Sci U S A (1982) 1.60
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models. Proc Natl Acad Sci U S A (2001) 1.58
An activated rasN gene: detected in late but not early passage human PA1 teratocarcinoma cells. Science (1984) 1.56
Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways. Cancer Res (2000) 1.56
Cells transformed by certain strains of Moloney sarcoma virus contain murine p60. Cell (1977) 1.56
Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. Proc Natl Acad Sci U S A (1991) 1.53
Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS. Biochemistry (1995) 1.52
Down-regulation of MET, the receptor for hepatocyte growth factor. Oncogene (2001) 1.52
Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis. Int J Cancer (1999) 1.52
Expression of interleukin-1beta in human breast carcinoma. Cancer (1997) 1.52
Met expression and sarcoma tumorigenicity. Cancer Res (1993) 1.50
Influenza virus-specific human cytotoxic T cell clones: heterogeneity in antigenic specificity and restriction by class II MHC products. Cell Immunol (1984) 1.50
Expression of scatter factor and c-met receptor in benign and malignant breast tissue. Cancer (1997) 1.50
Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury. Am J Pathol (1995) 1.49
Neurotrophin signalling pathways regulating neuronal apoptosis. Cell Mol Life Sci (2001) 1.46
Alcohol stimulates estrogen receptor signaling in human breast cancer cell lines. Cancer Res (2000) 1.46
Expression of brain-derived neurotrophic factor and p145TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. Cancer Res (1995) 1.45
Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo. Mol Cell Biol (1986) 1.45
Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase. J Biol Chem (1992) 1.44
Physical map of the origin of defective DNA in herpes simplex virus type 1 DNA. J Virol (1978) 1.44
Nucleotide sequence and biochemical activities of the Moloney murine sarcoma virus strain HT-1 mos gene. J Virol (1985) 1.44