Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver.

PubWeight™: 1.32‹?› | Rank: Top 10%

🔗 View Article (PMID 8385111)

Published in J Biol Chem on April 05, 1993

Authors

E I Closs1, L M Albritton, J W Kim, J M Cunningham

Author Affiliations

1: Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts.

Articles citing this

Regulatory and molecular aspects of mammalian amino acid transport. Biochem J (1994) 2.01

Cellular ADMA: regulation and action. Pharmacol Res (2009) 1.42

Structure and function of cationic amino acid transporters (CATs). J Membr Biol (2007) 1.35

L-arginine metabolism and its impact on host immunity against Leishmania infection. Immunol Res (2008) 1.21

Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic beta-cells. J Physiol (1997) 1.16

CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages. Biochem J (1999) 1.15

Hormonal regulation of the gene for the type C ecotropic retrovirus receptor in rat liver cells. J Virol (1994) 1.08

L-arginine and cationic amino acid transporter 2B regulate growth and survival of Leishmania amazonensis amastigotes in macrophages. Infect Immun (2007) 1.08

Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection. J Bacteriol (2006) 1.05

Discrimination between citrulline and arginine transport in activated murine macrophages: inefficient synthesis of NO from recycling of citrulline to arginine. Br J Pharmacol (1994) 1.02

Identification and characterization of an amino acid transporter expressed differentially in liver. Proc Natl Acad Sci U S A (2000) 1.02

Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome. PLoS One (2013) 0.98

Effects of Mycobacterium bovis BCG infection on regulation of L-arginine uptake and synthesis of reactive nitrogen intermediates in J774.1 murine macrophages. Infect Immun (2001) 0.98

L-Arginine currents in rat cardiac ventricular myocytes. J Physiol (2007) 0.95

Analysis of receptor usage by ecotropic murine retroviruses, using green fluorescent protein-tagged cationic amino acid transporters. J Virol (1999) 0.90

A mammalian arginine/lysine transporter uses multiple promoters. Proc Natl Acad Sci U S A (1995) 0.90

Induction of L-arginine transport and nitric oxide synthase in vascular smooth muscle cells: synergistic actions of pro-inflammatory cytokines and bacterial lipopolysaccharide. Br J Pharmacol (1995) 0.88

Role of plasma membrane transporters in muscle metabolism. Biochem J (2000) 0.88

A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling. J Biol Chem (2013) 0.85

Identification of a critical basic residue on the ecotropic murine leukemia virus receptor. J Virol (2003) 0.83

Cationic amino acid uptake constitutes a metabolic regulation mechanism and occurs in the flagellar pocket of Trypanosoma cruzi. PLoS One (2012) 0.82

Lysinuric protein intolerance (LPI) gene maps to the long arm of chromosome 14. Am J Hum Genet (1997) 0.81

Identification of cysteine residues in human cationic amino acid transporter hCAT-2A that are targets for inhibition by N-ethylmaleimide. J Biol Chem (2013) 0.79

Supplemental Citrulline Is More Efficient Than Arginine in Increasing Systemic Arginine Availability in Mice. J Nutr (2017) 0.77

Transmembrane signalling mechanisms regulating expression of cationic amino acid transporters and inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem J (1999) 0.77

D-enantiomers take a close look at the functioning of a cardiac cationic L-amino acid transporter. Biophys J (2010) 0.77

Analysis of cationic amino acid transport activity in canine lens epithelial cells. Exp Anim (2013) 0.76

Induction of arginase II by intestinal epithelium promotes the uptake of L-arginine from the lumen of Cryptosporidium parvum-infected porcine ileum. J Pediatr Gastroenterol Nutr (2008) 0.76

Uptake and metabolism of arginine impact Plasmodium development in the liver. Sci Rep (2017) 0.75

l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis. Front Immunol (2017) 0.75

Inotropic effects of L-lysine in the mammalian heart. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.75

Articles by these authors

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell (1989) 7.64

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature (1991) 5.40

Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell (2000) 4.88

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem (1992) 4.88

Biochemical evidence that patched is the Hedgehog receptor. Nature (1996) 4.53

Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes. Results of a multicentered randomized clinical trial. The Vitrectomy for Treatment of Macular Hole Study Group. Arch Ophthalmol (1997) 3.99

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. Cell (1991) 3.95

Regulation of phospholipase C-gamma 1 by profilin and tyrosine phosphorylation. Science (1991) 3.89

Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res (1998) 3.36

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat Genet (2000) 3.33

Characterization of a human colon/lung carcinoma oncogene. Nature (1983) 3.26

Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. Science (1997) 3.13

Survey of extended-spectrum beta-lactamases in clinical isolates of Escherichia coli and Klebsiella pneumoniae: prevalence of TEM-52 in Korea. J Clin Microbiol (1999) 3.04

The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell (1983) 3.00

Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res (1996) 2.89

Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J Virol (1993) 2.77

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell (1992) 2.67

Survey of Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: prevalence of SHV-12 and SHV-2a in Korea. J Clin Microbiol (1998) 2.66

Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy. Clin Pharmacol Ther (2007) 2.55

The regulated expression of erythropoietin by two human hepatoma cell lines. Proc Natl Acad Sci U S A (1987) 2.51

Vision-threatening complications of surgery for full-thickness macular holes. Vitrectomy for Macular Hole Study Group. Ophthalmology (1997) 2.49

Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology (2005) 2.45

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet (1995) 2.30

Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1. Nat Genet (1999) 2.28

Polyphosphoinositides produced by phosphatidylinositol 3-kinase are poor substrates for phospholipases C from rat liver and bovine brain. J Biol Chem (1989) 2.15

Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood (1999) 2.14

Normal values for high-resolution anorectal manometry/topography in a healthy Korean population and the effects of gender and body mass index. Neurogastroenterol Motil (2014) 2.14

Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron (2000) 2.04

Anchorage-independent cell growth signature identifies tumors with metastatic potential. Oncogene (2009) 1.99

Cross-modal plasticity and cochlear implants. Nature (2001) 1.92

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens. EMBO J (1998) 1.83

Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum Mol Genet (1996) 1.76

Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus. J Virol (1999) 1.75

Requirements for different components of the host cell cytoskeleton distinguish ecotropic murine leukemia virus entry via endocytosis from entry via surface fusion. J Virol (1997) 1.75

Molecular cloning and expression of a complementary DNA for inositol 1,4,5-trisphosphate 3-kinase. Science (1990) 1.70

The inflammation hypothesis of aging: molecular modulation by calorie restriction. Ann N Y Acad Sci (2001) 1.70

Evidence for a prostate cancer-susceptibility locus on chromosome 20. Am J Hum Genet (2000) 1.69

Human cells infected with retrovirus vectors acquire an endogenous murine provirus. J Virol (1990) 1.65

A genome scan for quantitative trait loci influencing carcass, post-natal growth and reproductive traits in commercial Angus cattle. Anim Genet (2010) 1.61

Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer. Cancer Res (1998) 1.55

Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. Br J Cancer (2009) 1.54

Heterotopic pancreas in the stomach: CT findings. Radiology (2000) 1.53

Common promoter polymorphism in monocyte differentiation antigen CD14 is associated with serum triglyceride levels and body mass index in non-diabetic individuals. Diabet Med (2006) 1.52

Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome. Bone Marrow Transplant (2001) 1.52

Discovery of a novel antitumor benzolactone enamide class that selectively inhibits mammalian vacuolar-type (H+)-atpases. J Pharmacol Exp Ther (2001) 1.51

Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of a domain that determines the transport properties of the MCAT proteins. J Biol Chem (1993) 1.49

Cervical cancer incidence and survival in Korea: 1993-2002. Int J Gynecol Cancer (2006) 1.48

Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-gamma in intact HSC-1 cells. J Biol Chem (1990) 1.47

Neural basis of endogenous and exogenous spatial orienting. A functional MRI study. J Cogn Neurosci (1999) 1.42

In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1. J Virol (1997) 1.41

Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling. Oncogene (2001) 1.40

Analysis of the murine ecotropic leukemia virus receptor reveals a common biochemical determinant on diverse cell surface receptors that is essential to retrovirus entry. J Virol (1996) 1.39

Monophosphoryl lipid A attenuates the effects of endotoxic shock in pigs. J Lab Clin Med (1992) 1.38

Modular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infection. Proc Natl Acad Sci U S A (2001) 1.37

Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4. Nat Neurosci (2001) 1.37

Suppression of a fusion defect by second site mutations in the ecotropic murine leukemia virus surface protein. J Virol (1999) 1.35

Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol (1999) 1.33

Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry (1997) 1.33

Genotyping CagA, VacA subtype, IceA1, and BabA of Helicobacter pylori isolates from Korean patients, and their association with gastroduodenal diseases. J Korean Med Sci (2001) 1.32

N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells. J Biol Chem (1993) 1.32

SLC6A4 variation and citalopram response. Am J Med Genet B Neuropsychiatr Genet (2009) 1.32

Increase in signal intensities on T1-weighted magnetic resonance images in asymptomatic manganese-exposed workers. Neurotoxicology (1999) 1.31

Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. EMBO J (1995) 1.30

Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers. Mol Genet Metab (2000) 1.28

Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets. FEMS Immunol Med Microbiol (1999) 1.27

Outcomes of transplantation with matched-sibling and unrelated-donor bone marrow in children with leukaemia. Lancet (1997) 1.25

Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt. Oncogene (1999) 1.24

Role of HPC2/ELAC2 in hereditary prostate cancer. Cancer Res (2001) 1.24

Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4. Mol Cell Biol (2000) 1.24

A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. J Thromb Haemost (2012) 1.23

The gene for HMSN2C maps to 12q23-24: a region of neuromuscular disorders. Neurology (2003) 1.22

The FeSII protein of Azotobacter vinelandii is not essential for aerobic nitrogen fixation, but confers significant protection to oxygen-mediated inactivation of nitrogenase in vitro and in vivo. Mol Microbiol (1994) 1.22

Interaction between human tRNA synthetases involves repeated sequence elements. Proc Natl Acad Sci U S A (1996) 1.21

HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res (2000) 1.20

Receptor binding transforms the surface subunit of the mammalian C-type retrovirus envelope protein from an inhibitor to an activator of fusion. J Virol (2001) 1.19

Genetic variation within the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways as risk factors for venous thromboembolism. J Thromb Haemost (2011) 1.19

Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter. Diabetes (2000) 1.18

Zinc as a paracrine effector in pancreatic islet cell death. Diabetes (2000) 1.17

Gene expression signatures associated with the resistance to imatinib. Leukemia (2006) 1.17

Apoptolidin, a new apoptosis inducer in transformed cells from Nocardiopsis sp. J Antibiot (Tokyo) (1997) 1.17

Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses. J Virol (1990) 1.16

Minus-strand DNA is present within murine type C ecotropic retroviruses prior to infection. J Virol (1993) 1.14

Neutrophil to lymphocyte ratio for preoperative diagnosis of uterine sarcomas: a case-matched comparison. Eur J Surg Oncol (2010) 1.13

The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the alpha- and beta-globin gene loci in an erythroid cell line. Proc Natl Acad Sci U S A (1997) 1.12

MS-275, a histone deacetylase inhibitor, selectively induces transforming growth factor beta type II receptor expression in human breast cancer cells. Cancer Res (2001) 1.12

Mapping of semantic, phonological, and orthographic verbal working memory in normal adults with functional magnetic resonance imaging. Neuropsychology (1999) 1.11

Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q. Am J Hum Genet (2003) 1.10

Idiopathic parkinsonism with superimposed manganese exposure: utility of positron emission tomography. Neurotoxicology (1999) 1.10

Melanocytic nevus with pregnancy-related changes in size accompanied by apoptosis of nevus cells: a case report. J Am Acad Dermatol (2000) 1.10

Regulation of D-myo-inositol 1,4,5-trisphosphate 3-kinase by cAMP-dependent protein kinase and protein kinase C. J Biol Chem (1990) 1.10

Anemia and perinatal death result from loss of the murine ecotropic retrovirus receptor mCAT-1. Genes Dev (1997) 1.10

Cloning, characterization, and functional expression of cDNAs encoding glucose transporter proteins from the human parasite Schistosoma mansoni. J Biol Chem (1994) 1.10

Differential expression of interleukin-8 and intercellular adhesion molecule-1 by human gingival epithelial cells in response to Actinobacillus actinomycetemcomitans or Porphyromonas gingivalis infection. Oral Microbiol Immunol (1998) 1.09

Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res (1998) 1.09

Anterior cingulotomy for refractory obsessive-compulsive disorder. Acta Psychiatr Scand (2003) 1.09

Comparison of risk factors and clinical responses to proton pump inhibitors in patients with erosive oesophagitis and non-erosive reflux disease. Aliment Pharmacol Ther (2009) 1.09

Graded zirconia glass for resistance to veneer fracture. J Dent Res (2010) 1.09