Published in Am J Physiol on May 01, 1993
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol Rev (1996) 3.46
Osmotically induced cell swelling versus cell shrinking elicits specific changes in phospholipid signals in tobacco pollen tubes. Plant Physiol (2004) 1.31
Integration of inositol phosphate signaling pathways via human ITPK1. J Biol Chem (2007) 1.01
INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia. Am J Respir Cell Mol Biol (2009) 0.79
Retracted State and spectral properties of chloride oscillations in pollen. Biophys J (2003) 0.75
CFTR as a cAMP-dependent regulator of sodium channels. Science (1995) 6.50
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell (1994) 4.80
A human colonic tumor cell line that maintains vectorial electrolyte transport. Am J Physiol (1984) 4.47
Occluding junction structure-function relationships in a cultured epithelial monolayer. J Cell Biol (1985) 4.21
Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet (1992) 4.12
Structural analysis of a human intestinal epithelial cell line. Gastroenterology (1987) 2.80
Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC). Gut (2003) 2.70
Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol (1990) 2.48
The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment. Proc Natl Acad Sci U S A (1993) 2.48
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. Gastroenterology (2001) 2.36
Phosphorylation of the cystic fibrosis transmembrane conductance regulator. J Biol Chem (1992) 2.28
Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line. J Clin Invest (1986) 2.24
Vasoactive intestinal polypeptide-induced chloride secretion by a colonic epithelial cell line. Direct participation of a basolaterally localized Na+,K+,Cl- cotransport system. J Clin Invest (1985) 2.01
Synergistic action of cyclic adenosine monophosphate- and calcium-mediated chloride secretion in a colonic epithelial cell line. J Clin Invest (1985) 1.87
Localization of the cystic fibrosis transmembrane conductance regulator in pancreas. J Clin Invest (1991) 1.74
Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR. Hum Mol Genet (1993) 1.71
Expression of the cystic fibrosis gene in adult human lung. J Clin Invest (1994) 1.70
Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. J Clin Invest (1997) 1.68
Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells. Mol Biol Cell (1996) 1.66
Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line. J Clin Invest (1985) 1.61
An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer. Proc Natl Acad Sci U S A (1993) 1.57
Somatostatin decreases diarrhea in patients with the short-bowel syndrome. J Clin Gastroenterol (1982) 1.50
Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury. Proc Natl Acad Sci U S A (1995) 1.48
Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line. J Clin Invest (1988) 1.47
The effects of donor and recipient practices on transplant center finances. Am J Transplant (2008) 1.44
Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. Hum Mol Genet (1993) 1.43
Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (1998) 1.38
Differing effects of apical and basolateral adenosine on colonic epithelial cell line T84. Am J Physiol (1989) 1.35
Long-term uncoupling of chloride secretion from intracellular calcium levels by Ins(3,4,5,6)P4. Nature (1994) 1.35
Regulation of membrane chloride currents in rat bile duct epithelial cells. J Clin Invest (1993) 1.33
Leptin acts as a mitogenic and antiapoptotic factor for colonic cancer cells. Br J Surg (2007) 1.32
T84 cell receptor binding and guanyl cyclase activation by Escherichia coli heat-stable toxin. Am J Physiol (1987) 1.31
Ba2+ inhibition of VIP- and A23187-stimulated Cl- secretion by T84 cell monolayers. Am J Physiol (1986) 1.23
Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles. J Biol Chem (1994) 1.22
Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides. J Biol Chem (1999) 1.22
Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol (1986) 1.22
Cyclic AMP and Ca2+-activated K+ transport in a human colonic epithelial cell line. J Biol Chem (1985) 1.22
A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START. EMBO J (1996) 1.21
Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion. J Biol Chem (1998) 1.20
Somatostatin inhibits diarrhea in the carcinoid syndrome. Ann Intern Med (1980) 1.19
Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line. Am J Physiol (1990) 1.18
Characterization of a cyclic AMP-activated Cl-transport pathway in the apical membrane of a human colonic epithelial cell line. J Biol Chem (1986) 1.18
Early bactericidal activity of isoniazid in pulmonary tuberculosis. Optimization of methodology. The DATRI 008 Study Group. Am J Respir Crit Care Med (1997) 1.13
Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides. Arthritis Rheum (1986) 1.10
Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing. Gene Ther (2000) 1.10
Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells. Am J Physiol (1998) 1.09
Immune-related intestinal Cl- secretion. I. Effect of histamine on the T84 cell line. Am J Physiol (1988) 1.09
ATP hydrolysis by a CFTR domain: pharmacology and effects of G551D mutation. Biochem Biophys Res Commun (2000) 1.08
G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexes. J Biol Chem (1995) 1.08
Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src). J Biol Chem (2000) 1.07
Functional characteristics of mucosal and connective tissue mast cells of man, the rat and other animals. Int Arch Allergy Appl Immunol (1985) 1.07
Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. Am J Physiol (1997) 1.07
Detection of viruses and body fluids which may contain viruses in the domestic environment. Epidemiol Infect (1998) 1.07
Calmodulin-stimulated protein kinase activity from rat pancreas. J Cell Biol (1983) 1.06
Preferential binding of vasoactive intestinal polypeptide to basolateral membrane of rat and rabbit enterocytes. J Clin Invest (1983) 1.06
Somatostatin inhibits fluid secretion in the rat jejunum. Gastroenterology (1980) 1.06
A biologic function for an "orphan" messenger: D-myo-inositol 3,4,5,6-tetrakisphosphate selectively blocks epithelial calcium-activated chloride channels. Proc Natl Acad Sci U S A (1996) 1.05
Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells. Am J Physiol (1996) 1.05
Mast cell heterogeneity: evidence and implications. J Clin Immunol (1984) 1.01
Elevation of inositol tetrakisphosphate parallels inhibition of Ca(2+)-dependent Cl- secretion in T84 cells. Am J Physiol (1993) 1.01
Somatostatin stimulates sodium and chloride absorption in the rabbit ileum. Gastroenterology (1980) 1.01
Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility. Mol Pharmacol (1994) 1.00
Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient. Am J Surg Pathol (2000) 1.00
Activation of mast cells by bile acids. Gastroenterology (1991) 1.00
Familial autoimmune haemolytic anaemia associated with rheumatoid arthritis and pernicious anaemia. Br J Haematol (1970) 1.00
Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretion. J Biol Chem (1996) 1.00
Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Immunol (1991) 0.99
Effect of somatostatin on ion transport in the rat colon. J Clin Invest (1980) 0.98
Carbachol-induced cytosolic free Ca2+ increases in T84 colonic cells seen by microfluorimetry. Am J Physiol (1989) 0.97
Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon. J Clin Invest (1995) 0.97
Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice. Nat Genet (1992) 0.96
Acetoxymethyl esters of phosphates, enhancement of the permeability and potency of cAMP. J Biol Chem (1993) 0.96
Cl- and K+ transport in human biliary cell lines. Gastroenterology (1993) 0.96
Complex pathogenesis of hyperoxaluria after jejunoileal bypass surgery. Oxalogenic substances in diet contribute to urinary oxalate. Gastroenterology (1983) 0.96
The effect of cryoprecipitate concentrate in patients with classical haemophilia. Lancet (1967) 0.94
A role for protein kinase cepsilon in the inhibitory effect of epidermal growth factor on calcium-stimulated chloride secretion in human colonic epithelial cells. J Biol Chem (2000) 0.94
Inhibition of IgE-mediated mast cell degranulation by sulphasalazine. Eur J Pharmacol (1985) 0.94
A surface antigen of Giardia lamblia with a glycosylphosphatidylinositol anchor. J Biol Chem (1991) 0.93
Cystic fibrosis in the pancreas: recent advances provide new insights. Curr Gastroenterol Rep (1999) 0.93
Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori-related duodenal ulcer: an Asian multicentre double-blind randomized placebo controlled study. Aliment Pharmacol Ther (2000) 0.92
EUS-guided choledochoduodenostomy for biliary drainage using tapered-tip plastic stent with multiple fangs. Endoscopy (2011) 0.92
A comparison of histamine secretion from isolated peritoneal mast cells of the mouse and rat. Int Arch Allergy Appl Immunol (1983) 0.91
Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation. Am J Physiol Cell Physiol (2001) 0.91
Missense mutation (G480C) in the CFTR gene associated with protein mislocalization but normal chloride channel activity. Hum Mol Genet (1995) 0.91
Clonidine and lidamidine (WHR-1142) stimulate sodium and chloride absorption in the rabbit intestine. Gastroenterology (1982) 0.90
Mast cells isolated from guinea-pig lung: characterization and studies on histamine secretion. Agents Actions (1983) 0.90
Evaluation of robotic-assisted laparoscopic and open pyeloplasty in children: single-surgeon experience. Ann R Coll Surg Engl (2015) 0.90
Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol. Clin Cancer Res (2001) 0.89
Inhibition of Ca(2+)-dependent Cl- secretion in T84 cells: membrane target(s) of inhibition is agonist specific. Am J Physiol (1998) 0.89
Nonmitogenic actions of growth factors: an integrated view of their role in intestinal physiology and pathophysiology. Gastroenterology (1997) 0.89
Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells. J Biol Chem (1985) 0.89
Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. Am J Physiol Cell Physiol (2001) 0.89
Mast cells are not essential to inflammation in murine model of colitis. Dig Dis Sci (1994) 0.87
Causes of chronic diarrhea in patients with AIDS in Thailand: a prospective clinical and microbiological study. J Gastroenterol (1996) 0.87
Mast cell heterogeneity in higher animals: a comparison of the properties of autologous lung and intestinal mast cells from nonhuman primates. J Immunol (1986) 0.86
A comparative study of histamine secretion from rat peritoneal and pleural mast cells. Agents Actions (1982) 0.85
Structure-activity relationships of somatostatin analogs in the rabbit ileum and the rat colon. J Clin Invest (1983) 0.85