Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

PubWeight™: 1.46‹?› | Rank: Top 5%

🔗 View Article (PMID 8420959)

Published in J Biol Chem on January 25, 1993

Authors

E Blachly-Dyson1, E B Zambronicz, W H Yu, V Adams, E R McCabe, J Adelman, M Colombini, M Forte

Author Affiliations

1: Vollum Institute for Advanced Biomedical Research, Portland, Oregon.

Articles citing this

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J Cell Biol (1994) 5.29

Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog (2005) 3.44

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene (2006) 2.96

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med (2000) 2.62

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. PLoS One (2008) 1.87

Glycogen synthase kinase 3 inhibition slows mitochondrial adenine nucleotide transport and regulates voltage-dependent anion channel phosphorylation. Circ Res (2008) 1.60

The evolutionary history of mitochondrial porins. BMC Evol Biol (2007) 1.18

VDAC1: from structure to cancer therapy. Front Oncol (2012) 1.16

Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein. Mol Cell Biol (1997) 1.15

Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. J Clin Invest (2005) 1.13

Molecular dynamics studies of ion permeation in VDAC. Biophys J (2011) 1.09

High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II. J Membr Biol (2007) 1.06

Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents. J Bioenerg Biomembr (2008) 1.04

Human mitochondrial transmembrane metabolite carriers: tissue distribution and its implication for mitochondrial disorders. J Bioenerg Biomembr (1998) 1.02

Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes. Proc Natl Acad Sci U S A (1994) 1.01

Two-color STED microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms. PMC Biophys (2010) 1.01

The physiological properties of a novel family of VDAC-like proteins from Drosophila melanogaster. Biophys J (2004) 0.99

Reflections on VDAC as a voltage-gated channel and a mitochondrial regulator. J Bioenerg Biomembr (2008) 0.97

New insights into the mechanism of permeation through large channels. Biophys J (2005) 0.94

Molecular and cell biology of a family of voltage-dependent anion channel porins in Lotus japonicus. Plant Physiol (2003) 0.93

Neurologic dysfunction and male infertility in Drosophila porin mutants: a new model for mitochondrial dysfunction and disease. J Biol Chem (2010) 0.93

Is the mitochondrial outermembrane protein VDAC1 therapeutic target for Alzheimer's disease? Biochim Biophys Acta (2012) 0.92

Mitochondrial and postmitochondrial survival signaling in cancer. Mitochondrion (2013) 0.90

Voltage-dependant anion channels: novel insights into isoform function through genetic models. Biochim Biophys Acta (2011) 0.90

Binding of rat brain hexokinase to recombinant yeast mitochondria: effect of environmental factors and the source of porin. J Bioenerg Biomembr (1998) 0.89

Five cases of isolated glycerol kinase deficiency, including two families: failure to find genotype:phenotype correlation. J Med Genet (2000) 0.89

Modulation of human mitochondrial voltage-dependent anion channel 2 (hVDAC-2) structural stability by cysteine-assisted barrel-lipid interactions. J Biol Chem (2013) 0.89

Importance of mitochondrial transmembrane processes in human mitochondriopathies. J Bioenerg Biomembr (1996) 0.85

Extramitochondrial porin: facts and hypotheses. J Bioenerg Biomembr (2000) 0.84

Influence of protein-micelle ratios and cysteine residues on the kinetic stability and unfolding rates of human mitochondrial VDAC-2. PLoS One (2014) 0.82

Homologous and heterologous interactions between hexokinase and mitochondrial porin: evolutionary implications. J Bioenerg Biomembr (1997) 0.82

VDAC3 has differing mitochondrial functions in two types of striated muscles. Biochim Biophys Acta (2010) 0.82

Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2. J Biomol NMR (2014) 0.82

Mitochondrial proteomics of nasopharyngeal carcinoma metastasis. BMC Med Genomics (2012) 0.82

Processes underlying the upregulation of Tom proteins in S. cerevisiae mitochondria depleted of the VDAC channel. J Bioenerg Biomembr (2004) 0.81

Cysteine residues impact the stability and micelle interaction dynamics of the human mitochondrial β-barrel anion channel hVDAC-2. PLoS One (2014) 0.80

Binding of rat brain hexokinase to recombinant yeast mitochondria: identification of necessary molecular determinants. J Bioenerg Biomembr (1999) 0.79

Purification and characterization of two voltage-dependent anion channel isoforms from plant seeds. Plant Physiol (2000) 0.78

Functional characterization of the conserved "GLK" motif in mitochondrial porin from Neurospora crassa. J Bioenerg Biomembr (2000) 0.78

Mitochondrial adenine nucleotide transport and cardioprotection. J Mol Cell Cardiol (2011) 0.77

Under conditions of insufficient permeability of VDAC1, external NADH may use the TOM complex channel to cross the outer membrane of Saccharomyces cerevisiae mitochondria. J Bioenerg Biomembr (2001) 0.76

Mitochondrial Ion Channels in Cancer Transformation. Front Oncol (2015) 0.76

Control of human VDAC-2 scaffold dynamics by interfacial tryptophans is position specific. Biochim Biophys Acta (2016) 0.75

Idiopathic male infertility in the Han population in China is affected by polymorphism in the VDAC2 gene. Oncotarget (2016) 0.75

Characterization of channel-forming activity in muscle biopsy from a porin-deficient human patient. J Bioenerg Biomembr (2000) 0.75

VDAC2-specific cellular functions and the underlying structure. Biochim Biophys Acta (2016) 0.75

The key role of the energized state of Saccharomyces cerevisiae mitochondria in modulations of the outer membrane channels by the intermembrane space proteins. J Bioenerg Biomembr (2002) 0.75

Articles by these authors

Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria. J Membr Biol (1976) 5.01

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes. Proc Natl Acad Sci U S A (1981) 4.28

Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation (2003) 3.86

Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies. Science (1996) 3.36

A candidate for the permeability pathway of the outer mitochondrial membrane. Nature (1979) 3.20

The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97

Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (1982) 2.96

Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation (1998) 2.90

DNA microextraction from dried blood spots on filter paper blotters: potential applications to newborn screening. Hum Genet (1987) 2.90

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J Biol Chem (2001) 2.76

Phenotypes of patients with "simple" Mendelian disorders are complex traits: thresholds, modifiers, and systems dynamics. Am J Hum Genet (2000) 2.67

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature (1994) 2.57

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proc Natl Acad Sci U S A (2000) 2.46

X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy (dystrophin) gene at the Xp21 locus. Circulation (1993) 2.30

Selectivity changes in site-directed mutants of the VDAC ion channel: structural implications. Science (1990) 2.15

Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res (2001) 2.12

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell (2001) 2.12

Molecular genetic diagnosis of sickle cell disease using dried blood specimens on blotters used for newborn screening. Hum Genet (1989) 2.11

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function. Biophys J (1997) 2.09

A mitochondrial perspective on cell death. Trends Biochem Sci (2001) 1.98

Human fibroblast interferon gene lacks introns. Nucleic Acids Res (1981) 1.98

VDAC, a channel in the outer mitochondrial membrane. Ion Channels (1996) 1.97

Regulation of metabolite flux through voltage-gating of VDAC channels. J Membr Biol (1997) 1.94

Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors. Cancer Res (1999) 1.93

Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster. Curr Biol (2000) 1.90

ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane. J Biol Chem (1996) 1.84

Duty to re-contact. Genet Med (2001) 1.80

Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidase. Proc Natl Acad Sci U S A (1999) 1.79

A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal. Nat Genet (1994) 1.78

The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. J Biol Chem (2000) 1.73

Guidelines for the retention, storage, and use of residual dried blood spot samples after newborn screening analysis: statement of the Council of Regional Networks for Genetic Services. Biochem Mol Med (1996) 1.72

Congenital adrenal hypoplasia, myopathy, and glycerol kinase deficiency: molecular genetic evidence for deletions. Am J Hum Genet (1987) 1.72

Prevalence of K329E mutation in medium-chain acyl-CoA dehydrogenase gene determined from Guthrie cards. Lancet (1991) 1.66

Biliopancreatic diversion for obesity at eighteen years. Surgery (1996) 1.66

Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex. J Cell Biol (2001) 1.65

Filtration removal of endotoxin (pyrogens) in solution in different states of aggregation. Appl Environ Microbiol (1977) 1.63

Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60

Structure and mode of action of a voltage dependent anion-selective channel (VDAC) located in the outer mitochondrial membrane. Ann N Y Acad Sci (1980) 1.59

DNA sequence of two closely linked human leukocyte interferon genes. Science (1981) 1.57

NADH regulates the gating of VDAC, the mitochondrial outer membrane channel. J Biol Chem (1994) 1.53

Homotransplantation of the liver in a patient with hepatoma and hereditary tyrosinemia. J Pediatr (1978) 1.53

Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel. Proc Natl Acad Sci U S A (1993) 1.52

Nonallergic angioedema: role of bradykinin. Allergy (2007) 1.50

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC. Biochemistry (1986) 1.49

Characterization of channels isolated from plant mitochondria. Methods Enzymol (1987) 1.49

VDAC channels. IUBMB Life (2002) 1.48

Use of the polymerase chain reaction for physical mapping of Escherichia coli genes. J Bacteriol (1991) 1.45

Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy. Nat Genet (2000) 1.44

Mouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability. J Membr Biol (1999) 1.44

An upper limit on the stochastic gravitational-wave background of cosmological origin. Nature (2009) 1.42

Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41

Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40

Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders. Springer Semin Immunopathol (2003) 1.40

Toward the molecular structure of the mitochondrial channel, VDAC. J Bioenerg Biomembr (1992) 1.39

The topology of VDAC as probed by biotin modification. J Biol Chem (1998) 1.39

Modifier genes convert "simple" Mendelian disorders to complex traits. Mol Genet Metab (2000) 1.39

Pityriasis rosea is not associated with human herpesvirus 7. Arch Dermatol (1999) 1.39

Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7  TeV. Phys Rev Lett (2011) 1.39

Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase. J Clin Invest (1988) 1.37

Cost-effectiveness of Veterans Administration hospital-based home care. A randomized clinical trial. Arch Intern Med (1990) 1.36

Large scale rearrangement of protein domains is associated with voltage gating of the VDAC channel. Biophys J (1992) 1.35

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34

Teenagers and alcohol misuse in the United States: by any definition, it's a big problem. Addiction (1996) 1.33

Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32

Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol (1997) 1.31

Neuropsychology of early-treated phenylketonuria: specific executive function deficits. Child Dev (1990) 1.31

Beta-NADH decreases the permeability of the mitochondrial outer membrane to ADP by a factor of 6. J Biol Chem (1994) 1.30

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L). Mol Cell Biol (2000) 1.29

Mutational analysis of 85 mucopolysaccharidosis type I families: frequency of known mutations, identification of 17 novel mutations and in vitro expression of missense mutations. Hum Genet (2001) 1.29

Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27

Isolation and characterization of acetylcholinesterase from Drosophila. J Biol Chem (1987) 1.27

The role of yeast VDAC genes on the permeability of the mitochondrial outer membrane. J Membr Biol (1998) 1.27

Zero-current potentials in a large membrane channel: a simple theory accounts for complex behavior. Biophys J (1993) 1.27

The sensor regions of VDAC are translocated from within the membrane to the surface during the gating processes. Biophys J (1998) 1.26

Bacterial expression and characterization of the mitochondrial outer membrane channel. Effects of n-terminal modifications. J Biol Chem (1998) 1.26

Na+-gradient-stimulated AIB transport in membrane vesicles from Ehrlich ascites cells. J Membr Biol (1974) 1.25

Efficient bacterial expression of bovine and porcine growth hormones. DNA (1983) 1.25

Bacterial species identification after DNA amplification with a universal primer pair. Mol Genet Metab (1999) 1.25

Immunological and molecular characterization of Go alpha-like proteins in the Drosophila central nervous system. J Biol Chem (1989) 1.25

Molecular genetics of the VDAC ion channel: structural model and sequence analysis. J Bioenerg Biomembr (1987) 1.24

Ultrasteep voltage dependence in a membrane channel. Proc Natl Acad Sci U S A (1987) 1.22

Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19

Mutant analysis shows that the Ca2+-induced K+ current shuts off one type of excitation in Paramecium. Proc Natl Acad Sci U S A (1983) 1.19

Porin interaction with hexokinase and glycerol kinase: metabolic microcompartmentation at the outer mitochondrial membrane. Biochem Med Metab Biol (1991) 1.18

The acquisition of anti-pneumococcal capsular polysaccharide Haemophilus influenzae type b and tetanus toxoid antibodies, with age, in the UK. Clin Exp Immunol (1993) 1.17

Targeting of hexokinase 1 to liver and hepatoma mitochondria. Proc Natl Acad Sci U S A (1992) 1.17

Dihydroceramide hinders ceramide channel formation: Implications on apoptosis. Apoptosis (2006) 1.16

The mitochondrial outer membrane channel, VDAC, is modulated by a soluble protein. FEBS Lett (1988) 1.16

ELISPOT assays provide reproducible results among different laboratories for T-cell immune monitoring--even in hands of ELISPOT-inexperienced investigators. J Immunotoxicol (2009) 1.16

Regulation of mitochondrial respiration by controlling the permeability of the outer membrane through the mitochondrial channel, VDAC. Biochim Biophys Acta (1992) 1.16

Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein. Mol Cell Biol (1997) 1.15