Nonprotein antigens of Borrelia burgdorferi.

Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete. Infect Immun (1995) 1.66

A newly discovered cholesteryl galactoside from Borrelia burgdorferi. Proc Natl Acad Sci U S A (2003) 1.48

Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete. Infect Immun (1995) 1.48

Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins. J Bacteriol (1994) 1.48

Borrelia burgdorferi RevA antigen is a surface-exposed outer membrane protein whose expression is regulated in response to environmental temperature and pH. Infect Immun (2001) 1.13

Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts. PLoS Pathog (2013) 1.09

Cholesterol lipids of Borrelia burgdorferi form lipid rafts and are required for the bactericidal activity of a complement-independent antibody. Cell Host Microbe (2010) 1.09

Experimental immunization with Borrelia burgdorferi induces development of antibodies to gangliosides. Infect Immun (1995) 1.00

Lipid exchange between Borrelia burgdorferi and host cells. PLoS Pathog (2013) 0.93

Strong IgG antibody responses to Borrelia burgdorferi glycolipids in patients with Lyme arthritis, a late manifestation of the infection. Clin Immunol (2009) 0.89

The bactericidal effect of a complement-independent antibody is osmolytic and specific to Borrelia. Proc Natl Acad Sci U S A (2009) 0.87

Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis. J Autoimmun (2016) 0.79

Synthesis and antigenicity of BBGL-2 glycolipids of Borrelia burgdorferi, the causative agent of Lyme disease. Carbohydr Res (2011) 0.78

Raft-like membrane domains in pathogenic microorganisms. Curr Top Membr (2015) 0.78

Increased IgA rheumatoid factor and V(H)1 associated cross reactive idiotype expression in patients with Lyme arthritis and neuroborreliosis. Ann Rheum Dis (1999) 0.76

Lyme disease-a tick-borne spirochetosis? Science (1982) 27.50

The spirochetal etiology of Lyme disease. N Engl J Med (1983) 21.59

Spirochetes isolated from the blood of two patients with Lyme disease. N Engl J Med (1983) 11.15

Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. Arthritis Rheum (1977) 9.14

Erythema chronicum migrans and Lyme arthritis. The enlarging clinical spectrum. Ann Intern Med (1977) 7.42

Western blotting in the serodiagnosis of Lyme disease. J Infect Dis (1993) 6.45

The early clinical manifestations of Lyme disease. Ann Intern Med (1983) 5.73

Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness. J Clin Invest (1986) 5.72

Natural Distribution of the Ixodes dammini spirochete. Science (1983) 5.24

Cases of Lyme disease in the United States: locations correlated with distribution of Ixodes dammini. Ann Intern Med (1979) 4.73

Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13

Lyme carditis: cardiac abnormalities of Lyme disease. Ann Intern Med (1980) 4.12

Antibodies of patients with Lyme disease to components of the Ixodes dammini spirochete. J Clin Invest (1983) 4.08

Comparison of immunoblotting and indirect enzyme-linked immunosorbent assay using different antigen preparations for diagnosing early Lyme disease. J Infect Dis (1988) 4.08

Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis. N Engl J Med (1994) 4.07

Antibody response in Lyme disease: evaluation of diagnostic tests. J Infect Dis (1984) 4.07

Neurologic abnormalities of Lyme disease. Medicine (Baltimore) (1979) 3.98

Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis. Science (1998) 3.68

The triad of neurologic manifestations of Lyme disease: meningitis, cranial neuritis, and radiculoneuritis. Neurology (1985) 3.55

Chronic neurologic manifestations of Lyme disease. N Engl J Med (1990) 3.54

Sensitive and specific serodiagnosis of Lyme disease by enzyme-linked immunosorbent assay with a peptide based on an immunodominant conserved region of Borrelia burgdorferi vlsE. J Clin Microbiol (1999) 3.41

Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi. N Engl J Med (1988) 3.26

Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice. Cell (1997) 3.25

The long-term clinical outcomes of Lyme disease. A population-based retrospective cohort study. Ann Intern Med (1994) 3.20

Isolation of antigenic components from the Lyme disease spirochete: their role in early diagnosis. J Infect Dis (1987) 3.13

Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi. Infect Immun (1993) 3.04

Experimental Lyme arthritis in rats infected with Borrelia burgdorferi. J Infect Dis (1988) 3.02

Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01

Antibiotic therapy in Lyme disease. Ann Intern Med (1980) 2.93

A distinct endothelial cell recognition system that controls lymphocyte traffic into inflamed synovium. Science (1986) 2.91

Treatment of the early manifestations of Lyme disease. Ann Intern Med (1983) 2.89

Interaction between Borrelia burgdorferi and endothelium in vitro. J Clin Invest (1990) 2.80

DNA characterization of the spirochete that causes Lyme disease. J Clin Microbiol (1984) 2.71

Humoral immune response to outer surface protein C of Borrelia burgdorferi in Lyme disease: role of the immunoglobulin M response in the serodiagnosis of early infection. Infect Immun (1994) 2.57

Erythema chronicum migrans and Lyme arthritis: epidemiologic evidence for a tick vector. Am J Epidemiol (1978) 2.53

A new Borrelia species isolated from patients with relapsing fever in Spain. Lancet (1996) 2.53

Empiric parenteral antibiotic treatment of patients with fibromyalgia and fatigue and a positive serologic result for Lyme disease. A cost-effectiveness analysis. Ann Intern Med (1993) 2.52

Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin. Ann Intern Med (1983) 2.50

Laboratory evaluation in the diagnosis of Lyme disease. Ann Intern Med (1997) 2.48

Diagnosing early Lyme disease. Am J Med (1985) 2.41

Handwashing practices for the prevention of nosocomial infections. Ann Intern Med (1975) 2.36

Intralaboratory reliability of serologic and urine testing for Lyme disease. Am J Med (2001) 2.34

Successful parenteral penicillin therapy of established Lyme arthritis. N Engl J Med (1985) 2.23

Possible nosocomial transmission of group B streptococci in a newborn nursery. J Pediatr (1975) 2.21

Selection of an escape variant of Borrelia burgdorferi by use of bactericidal monoclonal antibodies to OspB. Infect Immun (1992) 2.19

Treatment of early Lyme disease. Am J Med (1992) 2.18

Clinical pathologic correlations of Lyme disease by stage. Ann N Y Acad Sci (1988) 2.16

The geographic spread and temporal increase of the Lyme disease epidemic. JAMA (1991) 2.11

Adherence of the Lyme disease spirochete to glial cells and cells of glial origin. J Infect Dis (1989) 2.06

Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet (1993) 2.05

Fatal pancarditis in a patient with coexistent Lyme disease and babesiosis. Demonstration of spirochetes in the myocardium. Ann Intern Med (1985) 2.04

Lyme arthritis. Spirochetes found in synovial microangiopathic lesions. Am J Pathol (1985) 2.03

Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferi. Arthritis Rheum (1999) 2.01

Human antibody responses to VlsE antigenic variation protein of Borrelia burgdorferi. J Clin Microbiol (1999) 1.95

Adult Ixodes dammini on rabbits: a hypothesis for the development and transmission of Borrelia burgdorferi. J Infect Dis (1987) 1.91

A quantitative difference in the immune response between male and female mice. Proc Soc Exp Biol Med (1968) 1.90

Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers. Infect Immun (1995) 1.89

Transplacental/perinatal babesiosis. J Pediatr (1987) 1.89

Interactions of phagocytes with the Lyme disease spirochete: role of the Fc receptor. J Infect Dis (1984) 1.88

Lyme borreliosis: host responses to Borrelia burgdorferi. Microbiol Rev (1991) 1.87

High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452. Am J Pathol (1988) 1.86

Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis (2000) 1.82

Invasive aspergillosis in acute leukemia: correlation with nose cultures and antibiotic use. Ann Intern Med (1979) 1.79

The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis. Infect Immun (1999) 1.79

Chronic Lyme arthritis. Clinical and immunogenetic differentiation from rheumatoid arthritis. Ann Intern Med (1979) 1.79

Serological evidence for simultaneous occurrences of Lyme disease and babesiosis. J Infect Dis (1985) 1.76

The rising incidence of clinical Babesia microti infection. Hum Pathol (1981) 1.71

The T-cell proliferative assay in the diagnosis of Lyme disease. Ann Intern Med (1991) 1.70

Lyme arthritis: correlation of serum and cryoglobulin IgM with activity, and serum IgG with remission. Arthritis Rheum (1979) 1.70

The clinical spectrum and treatment of Lyme disease. Yale J Biol Med (1985) 1.70

Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme disease. Infect Immun (1995) 1.68

Identification and characterization of an endoflagellar antigen of Borrelia burgdorferi. J Clin Invest (1989) 1.68

Characterization of antigenic determinants of Borrelia burgdorferi shared by other bacteria. J Infect Dis (1992) 1.65

The long-term course of Lyme arthritis in children. N Engl J Med (1991) 1.63

Interleukin 1: a common endogenous mediator of inflammation and the local Shwartzman reaction. J Immunol (1986) 1.62

Glycolytic enzyme operon of Borrelia burgdorferi: characterization and evolutionary implications. Gene (1997) 1.62

Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers. Proc Natl Acad Sci U S A (2000) 1.61

Human babesiosis in New York State: an epidemiological description of 136 cases. Clin Infect Dis (1992) 1.61

An animal model for Lyme arthritis. Ann N Y Acad Sci (1988) 1.60

Chemical and biologic characterization of a lipopolysaccharide extracted from the Lyme disease spirochete (Borrelia burgdorferi). J Infect Dis (1985) 1.58

Lyme disease spirochetes induce human and murine interleukin 1 production. J Immunol (1985) 1.57

Longitudinal assessment of the clinical and epidemiological features of Lyme disease in a defined population. J Infect Dis (1986) 1.56

Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J Immunol (1998) 1.53

Immune complexes and the evolution of Lyme arthritis. Dissemination and localization of abnormal C1q binding activity. N Engl J Med (1979) 1.53

Sequestration of antibody to Borrelia burgdorferi in immune complexes in seronegative Lyme disease. Lancet (1990) 1.52

Spirochete-associated arthritis (Lyme disease) in a dog. J Am Vet Med Assoc (1984) 1.52

A murine IgM monoclonal antibody binds an antigenic determinant in outer surface protein A, an immunodominant basic protein of the Lyme disease spirochete. J Immunol (1988) 1.50

Lyme disease. Adv Intern Med (1995) 1.49

Effect of immunological unresponsiveness on different cell populations. Transplant Rev (1972) 1.45

Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clin Infect Dis (2001) 1.45

Recovery of Lyme disease spirochetes from patients. Yale J Biol Med (1985) 1.42

Pseudomonas species bacteremia caused by contaminated normal human serum albumin. J Infect Dis (1977) 1.42

Antibody responses to the three genomic groups of Borrelia burgdorferi in European Lyme borreliosis. J Infect Dis (1994) 1.41

The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritis. J Exp Med (1994) 1.41