Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 8463306)

Published in J Biol Chem on April 15, 1993

Authors

E Ortí1, L M Hu, A Munck

Author Affiliations

1: Department of Physiology, Dartmouth Medical School, Lebanon, New Hampshire 03756.

Articles by these authors

T cell growth factor receptors. Quantitation, specificity, and biological relevance. J Exp Med (1981) 10.66

Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr Rev (1984) 5.36

Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice. J Cyst Fibros (2008) 2.56

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science (1992) 2.24

Out-of-hours service in Denmark: the effect of a structural change. Br J Gen Pract (1998) 2.07

Specific and nonspecific physicochemical interactions of glucocorticoids and related steroids with rat thymus cells in vitro. J Biol Chem (1968) 1.95

Interaction of glucocorticoids with macrophages. Identification of glucocorticoid receptors in monocytes and macrophages. J Exp Med (1978) 1.75

Glucocorticoids and immune responses. Arthritis Rheum (1979) 1.65

Recommendations for the classification of diseases as CFTR-related disorders. J Cyst Fibros (2011) 1.54

Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein. J Biol Chem (1997) 1.50

Glucocorticoid inhibition of glucose uptake by peripheral tissues: old and new evidence, molecular mechanisms, and physiological significance. Perspect Biol Med (1971) 1.46

[Currarino syndrome: an association not to be overlooked]. Arch Fr Pediatr (1991) 1.41

Liver cirrhosis in cystic fibrosis--therapeutic implications and long term follow up. Arch Dis Child (1993) 1.36

MLC-conditioned media stimulate an increase in Fc receptors on human macrophages. J Immunol (1981) 1.34

Metabolic site and time course of cortisol action on glucose uptake, lactic acid output, and glucose 6-phosphate levels of rat thymus cells in vitro. J Biol Chem (1968) 1.31

Prostaglandin inhibition of T-cell proliferation is mediated at two levels. Cell Immunol (1981) 1.30

Patient delay from onset of chest pain suggesting acute coronary syndrome to hospital admission. Scand Cardiovasc J (2003) 1.27

Specific glucocorticoid receptors in thymus cells. Localization in the nucleus and extraction of the cortisol-receptor complex. J Biol Chem (1970) 1.26

The development of quality circles/peer review groups as a method of quality improvement in Europe. Results of a survey in 26 European countries. Fam Pract (2003) 1.25

Phosphorylation of steroid hormone receptors. Endocr Rev (1992) 1.22

Glucocorticoid-receptor complexes and the earliest steps in the action of glucocorticoids on thymus cells. J Steroid Biochem (1972) 1.16

Cystic fibrosis-related diabetes mellitus: clinical impact of prediabetes and effects of insulin therapy. Acta Paediatr (2001) 1.14

A European consensus for the evaluation and management of infants with an equivocal diagnosis following newborn screening for cystic fibrosis. J Cyst Fibros (2008) 1.12

Glucocorticoid receptor phosphorylation: overview, function and cell cycle-dependence. J Steroid Biochem Mol Biol (1998) 1.12

Glucocorticoid-receptor complexes in rat thymus cells. "Cytoplasmic"-nuclear transformations. J Biol Chem (1974) 1.09

Glucocorticoid inhibition of lymphokine secretion by alloreactive T lymphocyte clones. J Immunol (1984) 1.05

Agonist-dependent phosphorylation and nuclear dephosphorylation of glucocorticoid receptors in intact cells. J Biol Chem (1989) 1.03

In vitro actions of glucocorticoids on murine macrophages: effects on glucose transport and metabolism, growth in culture, and protein synthesis. J Immunol (1980) 1.02

Glucocorticoids inhibit expression of Fc receptors on the human granulocytic cell line HL-60. Nature (1979) 1.02

Glucocorticoid receptors and glucocorticoid-sensitive secretion of neutral proteinases in a macrophage line. J Immunol (1978) 1.02

Evidence for irreversible, actinomycin D-sensitive, and temperature-sensitive steps following binding of cortisol to glucocorticoid receptors and preceding effects on glucose metabolism in rat thymus cells. J Biol Chem (1971) 1.01

Glucocorticoid physiology, pharmacology and stress. Adv Exp Med Biol (1986) 0.99

Methods for assessing hormone-receptor kinetics with cells in suspension: receptor-bound and nonspecifically bound hormone; cytoplasmic-nuclear translocation. Methods Enzymol (1975) 0.97

Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells. Biochem J (1973) 0.97

Molybdate-stabilized nonactivated glucocorticoid-receptor complexes contain a 90-kDa non-steroid-binding phosphoprotein that is lost on activation. J Biol Chem (1986) 0.97

The very low penetrance of cystic fibrosis for the R117H mutation: a reappraisal for genetic counselling and newborn screening. J Med Genet (2009) 0.96

Kinetics of glucocorticoid-receptor complexes in rat thymus cells. J Steroid Biochem (1977) 0.95

Peripheral actions of glucocorticoids. Annu Rev Physiol (1975) 0.95

Glucose transport in murine macrophages: in vitro characterization of the monosaccharide transport system of the thioglycollate-elicited mouse peritoneal macrophage. J Immunol (1980) 0.95

Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model. J Biol Chem (1984) 0.95

Cell cycle-dependent glucocorticoid receptor phosphorylation and activity. Mol Endocrinol (1994) 0.93

Dexamethasone causes translocation of glucose transporters from the plasma membrane to an intracellular site in human fibroblasts. J Biol Chem (1987) 0.92

Outcome of cystic fibrosis-associated liver cirrhosis: management of portal hypertension. J Hepatol (1999) 0.92

Glucocorticoid receptors lacking hormone-binding activity are bound in nuclei of ATP-depleted cells. Nature (1987) 0.92

Characterization of nonactivated and activated glucocorticoid-receptor complexes from intact rat thymus cells. J Biol Chem (1983) 0.92

Time course of early events in the action of glucocorticoids on rat thymus cells in vitro. Synthesis and turnover of a hypothetical cortisol-induced protein inhibition of glucose metabolism and of a presumed ribonucleic acid. J Biol Chem (1973) 0.91

Glucocorticoid actions on the immune system: inhibition of production of an Fc-receptor augmenting factor. J Steroid Biochem (1981) 0.89

Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis. Thorax (2009) 0.89

A new highly discriminatory multiplex capillary-based MLVA assay as a tool for the epidemiological survey of Pseudomonas aeruginosa in cystic fibrosis patients. Eur J Clin Microbiol Infect Dis (2012) 0.89

Activation of steroid hormone-receptor complexes in intact target cells in physiological conditions. Nature (1979) 0.88

Cytomegalovirus colitis in children with inflammatory bowel disease. Gut (2006) 0.86

Steroid concentration and tissue integrity as factors determining the physiological significance of effects of adrenal steroids in vitro. Endocrinology (1965) 0.86

Cell proliferation and early differentiation during embryonic development and metamorphosis of Hydractinia echinata. Development (1988) 0.86

Hormone-induced hyperphosphorylation of specific phosphorylated sites in the mouse glucocorticoid receptor. J Steroid Biochem Mol Biol (1995) 0.86

Activities in vitro of glucocorticoids and related steroids on glucose uptake by rat thymus cell suspensions. Endocrinology (1966) 0.86

Audit report from Greenland on nurses' tasks and perceived competency. Rural Remote Health (2012) 0.85

Glucocorticoids and lymphocytes. I. Increased glucocorticoid receptor levels in antigen-stimulated lymphocytes. J Immunol (1980) 0.85

Glucocorticoid effects on incorporation of lipid and protein precursors into rat thymus cell fractions. J Steroid Biochem (1980) 0.84

[Pancreatic involvement in inflammatory bowel diseases in children]. Arch Pediatr (2002) 0.84

Pharmacokinetics of intravenous methylprednisolone and oral prednisone in paediatric patients with inflammatory bowel disease during the acute phase and in remission. Eur J Clin Pharmacol (1998) 0.84

Sulfhydryl-modifying reagents reversibly inhibit binding of glucocorticoid-receptor complexes to DNA-cellulose. Biochemistry (1984) 0.83

Imitation of glucagon effects on splanchnic hemodynamics and liver function by N6,2'-O-dibutyryl 3',5'-cyclic AMP (DBcAMP) in cats. Acta Physiol Scand (1975) 0.83

Mechanisms of glucocorticoid-induced immunosuppression: inhibitory effects on expression of Fc receptors and production of T-cell growth factor. J Steroid Biochem (1980) 0.83

Validity of medical audit registrations. Scand J Prim Health Care (1994) 0.82

A dynamic model of glucocorticoid receptor phosphorylation and cycling in intact cells. J Steroid Biochem (1989) 0.82

Adrenergic versus VIPergic control of cyclic AMP in human colonic crypts. Peptides (1984) 0.82

[Iterative intestinal intussusception and appendiceal mucocele in an infant with mucoviscidosis]. Arch Pediatr (1998) 0.82

Glucocorticoid receptors: ATP and cell cycle dependence, phosphorylation, and hormone resistance. Am J Respir Crit Care Med (1996) 0.81

Control by basal phosphorylation of cell cycle-dependent, hormone-induced glucocorticoid receptor hyperphosphorylation. Mol Endocrinol (1997) 0.81

Activation of cytosolic glucocorticoid-receptor complexes in intact WEHI-7 cells does not dephosphorylate the steroid-binding protein. J Biol Chem (1987) 0.81

Glucocorticoid receptors in ATP-depleted cells. Dephosphorylation, loss of hormone binding, HSP90 dissociation, and ATP-dependent cycling. J Biol Chem (1994) 0.81

Glucocorticoid receptors in adult acute lymphoblastic leukemia. Cancer Res (1981) 0.81

[French guidelines for sweat test practice and interpretation for cystic fibrosis neonatal screening]. Arch Pediatr (2010) 0.81

Effects of ATP and pyrophosphate on properties of glucocorticoid-receptor complexes from rat thymus cells. J Biol Chem (1983) 0.80

Glucocorticoid receptors: ATP-dependent cycling and hormone-dependent hyperphosphorylation. J Steroid Biochem Mol Biol (1993) 0.80

Multiple forms of nuclear binding of glucocorticoid-receptor complexes in rat thymocytes. J Steroid Biochem (1980) 0.80

Population pharmacokinetics of ciprofloxacin in pediatric and adolescent patients with acute infections. Antimicrob Agents Chemother (2003) 0.80

Stabilization of labile glucocorticoid-receptor complexes from acute nonlymphocytic leukemia cells by a factor from chronic lymphocytic leukemia cells. Cancer Res (1984) 0.80

Glucocorticoid receptors and sensitivity of isolated human leukemia and lymphoma cells. Cancer Res (1978) 0.79

Forskolin stimulates adenylate cyclase in human colonic crypts: interaction with VIP. Eur J Pharmacol (1984) 0.79

Glucocorticoid receptors and actions in rat thymocytes and immunologically stimulated human peripheral lymphocytes. Monogr Endocrinol (1979) 0.79

Is nasal polyposis in cystic fibrosis a direct manifestation of genetic mutation or a complication of chronic infection? Rhinology (1996) 0.79

Apolipoprotein B48 glycosylation in abetalipoproteinemia and Anderson's disease. Gastroenterology (2001) 0.79

Glucocorticoid receptors and in vitro responses to glucocorticoid in acute nonlymphocytic leukemia. Cancer Res (1981) 0.78

Comparison of glucocorticoid-receptor complex binding to nuclei and DNA cellulose. Evidence for different forms of interaction. Biochim Biophys Acta (1978) 0.78

In-vitro glucocorticoid studies for predicting response to glucocorticoid therapy in adults with malignant lymphoma. Lancet (1980) 0.78

Liver hemodynamics and liver function in cats during graded hypoxic hypoxemia. Acta Physiol Scand (1976) 0.78

[Questions raised and answers provided since the French nationwide cystic fibrosis newborn screening program was initiated]. Arch Pediatr (2009) 0.78

Prevention of relapse by mesalazine (Pentasa) in pediatric Crohn's disease: a multicenter, double-blind, randomized, placebo-controlled trial. Gastroenterol Clin Biol (2008) 0.77

Evidence for distinct sulfhydryl groups associated with steroid- and DNA-binding domains of rat thymus glucocorticoid receptors. Biochemistry (1984) 0.77

Glucocorticoid actions on lymphoid tissue and the immune system: physiologic and therapeutic implications. Prog Clin Biol Res (1984) 0.77

Phosphorylated sites within the functional domains of the approximately 100-kDa steroid-binding subunit of glucocorticoid receptors. Biochemistry (1989) 0.77

Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells. Biochemistry (1988) 0.77

In situ management and molecular analysis of candidaemia related to a totally implantable vascular access in a cystic fibrosis patient. J Infect (1996) 0.76

Bioavailability of oral vitamin E formulations in adult volunteers and children with chronic cholestasis or cystic fibrosis. J Clin Pharm Ther (2009) 0.76

Long-term incubation of rat thymus cells: Cytolytic actions of glucocorticoids in vitro. Endocrinology (1975) 0.76

[Duodenal ulcer - multicenter double-blind study with proglumide]. Med Klin (1981) 0.76

[Treatment of virilizing adrenal hyperplasia in adolescents. Use and side-effects of dexamethasone]. Arch Fr Pediatr (1985) 0.76