Published in J Clin Invest on April 01, 1993
Insulin resistance and cardiovascular disease. J Clin Invest (2000) 4.05
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J (2011) 3.00
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest (1999) 2.77
Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease. J Clin Invest (1995) 2.20
Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion. Arterioscler Thromb Vasc Biol (2005) 1.43
Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men. J Clin Invest (1999) 1.35
Triglycerides and heart disease: still a hypothesis? Arterioscler Thromb Vasc Biol (2011) 1.32
Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake. J Biol Chem (2010) 1.22
Cubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosis. Proc Natl Acad Sci U S A (1999) 1.18
ABCA1 plays no role in the centripetal movement of cholesterol from peripheral tissues to the liver and intestine in the mouse. J Lipid Res (2009) 1.14
Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency. J Clin Invest (1993) 1.03
Obesity and altered glucose metabolism impact HDL composition in CETP transgenic mice: a role for ovarian hormones. J Lipid Res (2012) 0.99
Lipoprotein metabolism in chronic renal insufficiency. Pediatr Nephrol (2007) 0.96
Lower HDL-C and apolipoprotein A-I are related to higher glomerular filtration rate in subjects without kidney disease. J Lipid Res (2010) 0.92
Potent and selective PPAR-alpha agonist LY518674 upregulates both ApoA-I production and catabolism in human subjects with the metabolic syndrome. Arterioscler Thromb Vasc Biol (2008) 0.92
Novel Pathways of Apolipoprotein A-I Metabolism in High-Density Lipoprotein of Different Sizes in Humans. Arterioscler Thromb Vasc Biol (2015) 0.90
Imaging apolipoprotein AI in vivo. NMR Biomed (2011) 0.88
Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism. J Lipid Res (2009) 0.82
Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein. Arterioscler Thromb Vasc Biol (2016) 0.82
Lipid profile of type 2 diabetic and hypertensive patients in the jamaican population. J Lab Physicians (2010) 0.81
Hyperalphalipoproteinemia in human lecithin cholesterol acyltransferase transgenic rabbits. In vivo apolipoprotein A-I catabolism is delayed in a gene dose-dependent manner. J Clin Invest (1996) 0.78
Effluxed lipids: Tangier Island's latest export. Proc Natl Acad Sci U S A (1999) 0.78
Influence of Route of Administration and Lipidation of Apolipoprotein A-I Peptide on Pharmacokinetics and Cholesterol Mobilization. J Lipid Res (2016) 0.77
Apolipoproteins A-I, B, and C-III in young adult Cherokee with metabolic syndrome with or without type 2 diabetes. J Clin Lipidol (2012) 0.76
Increased production rates of LDL are common in individuals with low plasma levels of HDL cholesterol, independent of plasma triglyceride concentrations. Arterioscler Thromb (1993) 0.75
High-density-lipoprotein cholesterol and atherosclerosis. CMAJ (1993) 0.75
High-Density Lipoprotein, Lecithin: Cholesterol Acyltransferase, and Atherosclerosis. Endocrinol Metab (Seoul) (2016) 0.75
Treatment of Dyslipidemias to Prevent Cardiovascular Disease in Patients with Type 2 Diabetes. Curr Cardiol Rep (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest (1955) 31.08
Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study. JAMA (1986) 7.23
The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study. Lancet (1977) 5.10
Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro. J Biol Chem (1985) 1.86
Tissue sites of degradation of apoprotein A-I in the rat. J Biol Chem (1983) 1.77
Apoproteins B and A-I and coronary artery disease in humans. Arteriosclerosis (1984) 1.73
High-density lipoprotein cholesterol and coronary heart disease in hypercholesterolemic men: the Lipid Research Clinics Coronary Primary Prevention Trial. Circulation (1986) 1.57
Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia. J Clin Invest (1991) 1.42
Elevated high density lipoprotein cholesterol levels correlate with decreased apolipoprotein A-I and A-II fractional catabolic rate in women. J Clin Invest (1989) 1.40
Physiological evaluation of the isolated perfused rat kidney. Am J Physiol (1980) 1.27
Role of lipoprotein lipase in the regulation of high density lipoprotein apolipoprotein metabolism. Studies in normal and lipoprotein lipase-inhibited monkeys. J Clin Invest (1990) 1.08
Hepatic lipase promotes a loss of apolipoprotein A-I from triglyceride-enriched human high density lipoproteins during incubation in vitro. Arterioscler Thromb (1991) 1.05
An international collaborative study on standardization of apolipoproteins A-I and B. Part I. Evaluation of a lyophilized candidate reference and calibration material. Clin Chem (1987) 0.99
Heterogeneity of apolipoprotein A-I turnover in subjects with reduced concentrations of plasma high density lipoprotein cholesterol. Metabolism (1988) 0.97
High-density lipoprotein metabolism. Adv Lipid Res (1980) 0.95
The in vitro interaction of human apolipoprotein A-I and high density lipoproteins. Biochim Biophys Acta (1977) 0.93
A comparative study of post-heparin lipolytic activity and a purified human plasma triacylglycerol lipase. Biochim Biophys Acta (1974) 0.92
A comparison of two methods to investigate the metabolism of human apolipoproteins A-I and and A-II. J Lipid Res (1978) 0.90
The composition and metabolism of high density lipoprotein subfractions. Lipids (1979) 0.89
High density lipoproteinuria in nephrotic syndrome. Metabolism (1976) 0.89
Preparation of a homogeneous and stable form of bovine milk lipoprotein lipase. Prep Biochem (1985) 0.88
Stability of free apolipoprotein A-1 concentration in serum, and its measurement in normal and hyperlipidemic subjects. Clin Chem (1987) 0.88
Plasma, apolipoprotein, A-I and A-II levels in hyperlipidemia. Lipids (1978) 0.87
High-density lipoprotein apolipoproteins in urine: II. Enzyme-linked immunoassay of apolipoprotein A-I. Clin Chem (1988) 0.86
Rapid fractionation of human high density apolipoproteins by high performance liquid chromatography. Lipids (1981) 0.86
Evaluation of a method for study of kinetics of autologous apolipoprotein A-I. J Lipid Res (1991) 0.82
Quantitative determination of apolipoprotein A-I in high-density lipoproteins and 'free' apolipoprotein A-I by two-dimensional agarose gel lipoprotein-'rocket' immunoelectrophoresis of human serum. Biochim Biophys Acta (1986) 0.82
The effect of renal failure and haemodialysis on the concentration of free apolipoprotein A-1 in serum and the implications for the catabolism of high-density lipoproteins. Clin Chim Acta (1988) 0.80
Renal handling of high-density lipoproteins by isolated perfused kidneys. Metabolism (1984) 0.80
The immunochemical determination of apolipoprotein A, total apolipoprotein A-I and 'free' apolipoprotein A-I in serum of patients on chronic haemodialysis. Ann Clin Biochem (1984) 0.79
Lipoprotein lipase prevents the hepatic lipase-induced reduction in particle size of high density lipoproteins during incubation of human plasma. Atherosclerosis (1990) 0.78
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A (2001) 5.48
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation (2000) 4.80
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J Clin Invest (1992) 2.80
Blindness and vision impairment in a rural south Indian population: the Aravind Comprehensive Eye Survey. Ophthalmology (2003) 2.64
A population based eye survey of older adults in Tirunelveli district of south India: blindness, cataract surgery, and visual outcomes. Br J Ophthalmol (2002) 2.60
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest (1995) 2.48
Microbial keratitis in South India: influence of risk factors, climate, and geographical variation. Ophthalmic Epidemiol (2007) 2.19
HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia. Nat Med (2001) 2.14
Is hypertriglyceridemia a risk factor for atherosclerotic cardiovascular disease? A simple question with a complicated answer. Ann Intern Med (1997) 2.04
Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. J Clin Invest (1986) 1.96
Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study. Indian J Ophthalmol (2003) 1.93
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Stroke (2000) 1.90
The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70. J Biol Chem (1997) 1.87
Lack of correlation of degree of villous atrophy with severity of clinical presentation of coeliac disease. Dig Liver Dis (2006) 1.84
Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B. J Biol Chem (1991) 1.73
Regulation of hepatic secretion of apolipoprotein B-containing lipoproteins: information obtained from cultured liver cells. J Lipid Res (1993) 1.68
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery : roles of VLDL and HDL. Circ Res (2000) 1.67
Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J Biol Chem (1999) 1.64
Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia. J Clin Invest (1998) 1.63
A long-term dose-response study of mitomycin in glaucoma filtration surgery. Arch Ophthalmol (1997) 1.58
Plasma delivery of retinoic acid to tissues in the rat. J Biol Chem (1995) 1.57
Physicians' metered dose inhaler technique after a single teaching session. Ann Allergy Asthma Immunol (1996) 1.56
Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions. Proc Natl Acad Sci U S A (1991) 1.55
HDL-subpopulation patterns in response to reductions in dietary total and saturated fat intakes in healthy subjects. Am J Clin Nutr (1999) 1.54
Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma. J Biol Chem (1997) 1.49
Utilisation of eye care services in rural south India: the Aravind Comprehensive Eye Survey. Br J Ophthalmol (2004) 1.48
Nocardia asteroides keratitis in south India. Indian J Med Microbiol (2007) 1.45
Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse. Science (1983) 1.44
Regulated Co-translational ubiquitination of apolipoprotein B100. A new paradigm for proteasomal degradation of a secretory protein. J Biol Chem (1998) 1.44
Reducing total dietary fat without reducing saturated fatty acids does not significantly lower total plasma cholesterol concentrations in normal males. Am J Clin Nutr (1992) 1.42
Aetiological diagnosis of microbial keratitis in South India - a study of 1618 cases. Indian J Med Microbiol (2007) 1.41
Etiology and antibacterial susceptibility pattern of community-acquired bacterial ocular infections in a tertiary eye care hospital in south India. Indian J Ophthalmol (2010) 1.40
Safety and efficacy of Omacor in severe hypertriglyceridemia. J Cardiovasc Risk (1999) 1.40
Lipoprotein metabolism during acute inhibition of hepatic triglyceride lipase in the cynomolgus monkey. J Clin Invest (1982) 1.39
Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons. Gene Ther (1998) 1.36
Prevalence of bacterial pathogens causing ocular infections in South India. Indian J Pathol Microbiol (2010) 1.35
Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo. Proc Natl Acad Sci U S A (1998) 1.31
Lipoprotein lipase hydrolysis of retinyl ester. Possible implications for retinoid uptake by cells. J Biol Chem (1994) 1.31
Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects. Effect of weight loss. J Clin Invest (1985) 1.23
L-asparaginases from Mycobacterium tuberculosis strains H37Rv and H37Ra. Arch Biochem Biophys (1968) 1.23
An immunologically active arabinogalactan from Tinospora cordifolia. Phytochemistry (1999) 1.22
Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA. J Biol Chem (1991) 1.22
The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection. J Virol (1993) 1.22
Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor. J Biol Chem (2000) 1.21
Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase. J Biol Chem (1994) 1.20
Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages. J Clin Invest (1992) 1.20
Analysis of the risk factors predisposing to fungal, bacterial & Acanthamoeba keratitis in south India. Indian J Med Res (2009) 1.18
Basic pharmacodynamic models for agents that alter production of natural cells. J Pharmacokinet Biopharm (1999) 1.17
Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester. J Lipid Res (1999) 1.17
Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix. J Clin Invest (1992) 1.16
Monoclonal antibody inhibition of cholesteryl ester transfer protein activity in the rabbit. Effects on lipoprotein composition and high density lipoprotein cholesteryl ester metabolism. J Clin Invest (1989) 1.16
Estimation of measles vaccination coverage using the Lot Quality Assurance Sampling (LQAS) method--Tamilnadu, India, 2002-2003. MMWR Morb Mortal Wkly Rep (2006) 1.16
Risk factors for age related cataract in a rural population of southern India: the Aravind Comprehensive Eye Study. Br J Ophthalmol (2004) 1.16
Anterior segment optical coherence tomography documentation of a case of topiramate induced acute angle closure. Indian J Ophthalmol (2014) 1.16
Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids. J Biol Chem (1989) 1.16
Changes in plasma lipids and lipoproteins during isotretinoin therapy for acne. N Engl J Med (1985) 1.15
Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA Study, protocol 1. Arterioscler Thromb Vasc Biol (1998) 1.15
Suppression of apolipoprotein B production during treatment of cholesteryl ester storage disease with lovastatin. Implications for regulation of apolipoprotein B synthesis. J Clin Invest (1987) 1.14
Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. J Clin Invest (1997) 1.14
Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins. Circulation (1998) 1.14
Localization of lipoprotein lipase mRNA in selected rat tissues. J Lipid Res (1989) 1.13
Replication-defective herpes simplex virus vectors for gene transfer in vivo. Proc Natl Acad Sci U S A (1996) 1.12
Pseudoexfoliation in a rural population of southern India: the Aravind Comprehensive Eye Survey. Am J Ophthalmol (2003) 1.12
Increasing incidence of malaria in Kurseong, Darjeeling District, West Bengal, India, 2000-2004. Trans R Soc Trop Med Hyg (2008) 1.11
Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence. Proc Natl Acad Sci U S A (1998) 1.11
Sensitivity of the immunological response to the nutritional status of rats. J Nutr (1972) 1.11
Retinol binding protein as a surrogate measure for serum retinol: studies in vitamin A-deficient children from the Republic of the Marshall Islands. Am J Clin Nutr (2001) 1.10
Human plasma LDL cryopreserved with sucrose maintains in vivo kinetics indistinguishable from freshly isolated human LDL in cynomolgus monkeys. J Lipid Res (1994) 1.10
Scrub typhus in Darjeeling, India: opportunities for simple, practical prevention measures. Trans R Soc Trop Med Hyg (2009) 1.10
Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective deficiency of brown adipose tissue, obesity, and insulin resistance. J Biol Chem (2001) 1.10
A mouse model with features of familial combined hyperlipidemia. Science (1997) 1.09
Metabolism of endothelial cell-bound lipoprotein lipase. Evidence for heparan sulfate proteoglycan-mediated internalization and recycling. J Biol Chem (1990) 1.09
Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein Cl. J Clin Invest (1996) 1.09
Independent regulation of plasma apolipoprotein C-II and C-III concentrations in very low density and high density lipoproteins: implications for the regulation of the catabolism of these lipoproteins. J Lipid Res (1988) 1.09
Plasma lipid transfer protein as a determinant of the atherogenicity of monkey plasma lipoproteins. J Clin Invest (1991) 1.09
Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues. J Clin Invest (2001) 1.08
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. J Clin Invest (1994) 1.08
Role of lipoprotein lipase in the regulation of high density lipoprotein apolipoprotein metabolism. Studies in normal and lipoprotein lipase-inhibited monkeys. J Clin Invest (1990) 1.08
Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1. J Biol Chem (2000) 1.08
Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes. Arterioscler Thromb Vasc Biol (2000) 1.07
Direct measurement of apoprotein B specific activity in 125I-labeled lipoproteins. J Lipid Res (1978) 1.07
Lipoprotein lipase increases lipoprotein binding to the artery wall and increases endothelial layer permeability by formation of lipolysis products. Circ Res (1997) 1.07
Growth, nutrient retention, and metabolic response of low-birth-weight infants fed supplemented and unsupplemented preterm human milk. Am J Clin Nutr (1990) 1.06
Prediction of the parameters of whole body cholesterol metabolism in humans. J Lipid Res (1980) 1.06
Microbiological diagnosis of infective keratitis: comparative evaluation of direct microscopy and culture results. Br J Ophthalmol (2006) 1.06
Lipoprotein metabolism during acute inhibition of lipoprotein lipase in the cynomolgus monkey. J Clin Invest (1988) 1.05