Published in Neuron on April 01, 1993
Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron (1995) 1.56
Receptor stimulation causes slow inhibition of IRK1 inwardly rectifying K+ channels by direct protein kinase A-mediated phosphorylation. Proc Natl Acad Sci U S A (1996) 1.06
Protein kinase A-dependent derepression of the human prodynorphin gene via differential binding to an intragenic silencer element. Mol Cell Biol (1998) 1.00
Therapeutic potential of RNA interference in pain medicine. Open Pain J (2009) 0.84
[Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor. Proc Natl Acad Sci U S A (1995) 0.79
DREAM controls the on/off switch of specific activity-dependent transcription pathways. Mol Cell Biol (2013) 0.79
Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice. Psychopharmacology (Berl) (2003) 0.76
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.76
MicroRNA circulating in the early aftermath of motor vehicle collision predict persistent pain development and suggest a role for microRNA in sex-specific pain differences. Mol Pain (2015) 0.75
DREAM is a Ca2+-regulated transcriptional repressor. Nature (1999) 3.54
Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature (1992) 2.78
E- and Z-10-hydroxylation of nortriptyline: relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther (1981) 1.41
Induction of CREM activator proteins in spermatids: down-stream targets and implications for haploid germ cell differentiation. Mol Endocrinol (1993) 1.31
Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization. Brain Res (1988) 1.28
Functional kainate-selective glutamate receptors in cultured hippocampal neurons. Proc Natl Acad Sci U S A (1993) 1.27
3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose. Psychopharmacology (Berl) (2001) 1.22
Independent expression of the alpha and beta c-erbA genes in developing rat brain. Mol Endocrinol (1991) 1.22
A neuroprotective phase precedes striatal degeneration upon nucleolar stress. Cell Death Differ (2013) 1.16
Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: clinical implications. Lancet (1981) 1.14
Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man. Life Sci (1980) 1.13
DREAM-alphaCREM interaction via leucine-charged domains derepresses downstream regulatory element-dependent transcription. Mol Cell Biol (2000) 1.09
The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ('ecstasy'). Neuropharmacology (1998) 1.09
Identification and functional characterization of a K+ channel alpha-subunit with regulatory properties specific to brain. J Neurosci (1997) 1.08
Clomipramine treatment of childhood obsessive-compulsive disorder. A double-blind controlled study. Arch Gen Psychiatry (1985) 1.07
Mechanisms of Ca(2+)-dependent transcription. Curr Opin Neurobiol (2001) 1.06
Molecular pathways of pain: Fos/Jun-mediated activation of a noncanonical AP-1 site in the prodynorphin gene. Neuron (1991) 1.04
Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. Biochem J (1993) 1.02
Transcriptional response to cAMP in brain: specific distribution and induction of CREM antagonists. Neuron (1993) 1.01
Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain. Neuropharmacology (2001) 1.00
Protein kinase A-dependent derepression of the human prodynorphin gene via differential binding to an intragenic silencer element. Mol Cell Biol (1998) 1.00
Pronounced inhibition of noradrenaline uptake by 10-hydroxymetabolites of nortriptyline. Life Sci (1979) 0.97
Thyroid hormones, learning and memory. Genes Brain Behav (2007) 0.96
Nortriptyline and debrisoquine hydroxylations in Ghanaian and Swedish subjects. Clin Pharmacol Ther (1984) 0.96
The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain. Br J Pharmacol (2001) 0.95
Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells. EMBO J (2001) 0.95
Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats. J Neurochem (2001) 0.94
Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver microsomes. Clin Pharmacol Ther (1984) 0.93
Distribution of insulin-like growth factor-I receptor mRNA in rat brain. Regulation in the hypothalamo-neurohypophysial system. J Mol Endocrinol (1993) 0.92
Ca2+-dependent transcriptional repression and derepression: DREAM, a direct effector. Semin Cell Dev Biol (2001) 0.91
Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects. Arch Gen Psychiatry (1980) 0.91
Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function. Nucleic Acids Res (1990) 0.91
Increased spinal cord dynorphin mRNA during peripheral inflammation. NIDA Res Monogr (1986) 0.89
Regulation of striatal enkephalin turnover in rats receiving antagonists of specific dopamine receptor subtypes. J Pharmacol Exp Ther (1987) 0.88
Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine. Br J Pharmacol (1993) 0.88
Correlation between nortriptyline and debrisoquine hydroxylation in the human liver. Life Sci (1983) 0.88
Functional N-methyl-D-aspartate receptors in clonal rat phaeochromocytoma cells. J Physiol (1996) 0.87
Differential expression of the jun family members in rat brain. Oncogene (1991) 0.87
Effect of clonidine, nimodipine and diltiazem on the in vitro opioid withdrawal response in the guinea-pig ileum. Br J Pharmacol (1990) 0.86
Proceedings: "First-pass" effect and dose dependent availability as factors contributing to interindividual differences in equilibrium concentrations of alprenolol in man. Acta Pharm Suec (1974) 0.86
Ion-pair liquid chromatography of amitriptyline and metabolites in plasma. J Chromatogr (1978) 0.86
Amitriptyline metabolism: association with debrisoquin hydroxylation in nonsmokers. Clin Pharmacol Ther (1986) 0.86
Importance of "first-pass elimination" for interindividual differences in steady-state concentrations of the adrenergic beta-receptor antagonist alprenolol. J Pharmacokinet Biopharm (1977) 0.86
The DREAM-DRE interaction: key nucleotides and dominant negative mutants. Biochim Biophys Acta (2000) 0.85
Dopamine D(1) receptor deletion strongly reduces neurotoxic effects of methamphetamine. Neurobiol Dis (2011) 0.85
Differential effect of thyroid hormone on NGFI-A gene expression in developing rat brain. Endocrinology (1994) 0.83
Comparative metabolism of debrisoquine, 7-ethoxyresorufin and benzo(a)pyrene in liver microsomes from humans, and from rats treated with cytochrome P-450 inducers. Acta Pharmacol Toxicol (Copenh) (1985) 0.83
Kindling enhances the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices. Brain Res (1986) 0.83
Uncoupled changes in the expression of the jun family members during myeloid cell differentiation. Eur J Biochem (1991) 0.82
PC12 cells differentiate into chromaffin cell-like phenotype in coculture with adrenal medullary endothelial cells. Proc Natl Acad Sci U S A (1990) 0.82
Expression of cholecystokinin and enkephalin mRNA in discrete brain regions. Peptides (1989) 0.82
Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes. Biochem J (1991) 0.82
Differential effects of unilateral olfactory deprivation on noradrenergic and cholinergic systems in the main olfactory bulb of the rat. Neuroscience (2006) 0.82
Proenkephalin gene expression in the PC12 pheochromocytoma cell line: stimulation by sodium butyrate. Endocrinology (1987) 0.82
A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term defect in thermoregulation. Psychopharmacology (Berl) (2001) 0.81
Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice. Br J Pharmacol (2009) 0.81
3,4-Methylenedioxymethamphetamine increases pro-interleukin-1beta production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: role of interleukin-1beta in neurotoxicity. Neuroscience (2005) 0.81
Evidence for a central but not adrenal, opioid mediation in hypertension induced by brief isolation in the rat. Life Sci (1986) 0.81
VIP gene expression in rat thymus and spleen. Brain Behav Immun (1993) 0.81
Analgesic effect of salmon-calcitonin administered by two routes. Effect on morphine analgesia. Eur J Pharmacol (1992) 0.81
In vitro study of the interaction of salmon calcitonin with mu, delta and kappa opioid agonists. Naunyn Schmiedebergs Arch Pharmacol (1993) 0.80
Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats. Neuropharmacology (2003) 0.80
Changes in the serotonergic system in the main olfactory bulb of rats unilaterally deprived from birth to adulthood. J Neurochem (2007) 0.80
Association between hypoalgesia and hypertension in rats after short-term isolation. Neuropharmacology (1985) 0.80
Permissive effect of dexamethasone on the increase of proenkephalin mRNA induced by depolarization of chromaffin cells. Proc Natl Acad Sci U S A (1986) 0.79
Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. Br J Pharmacol (2010) 0.79
Peripheral noxious stimulation induces CREM expression in dorsal horn: involvement of glutamate. Eur J Neurosci (1997) 0.79
Changes in the dynamic state of brain proenkephalin-derived peptides during amygdaloid kindling. J Neurosci Res (1986) 0.79
Co-induction of jun B and c-fos in a subset of neurons in the spinal cord. Oncogene (1991) 0.78
Expression of the prodynorphin gene in the developing and adult cerebral cortex of the rat: an in situ hybridization study. J Comp Neurol (1990) 0.78
Antinociceptive and Met-enkephalin releasing effects of tachykinins and substance P fragments. Peptides (1986) 0.78
Amitriptyline metabolism: relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther (1983) 0.78
Plasma levels of chlorimipramine and its demethyl metabolite during treatment of depression. Clin Pharmacol Ther (1979) 0.77
The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine. Neuropharmacology (1996) 0.77
Interindividual differences in amitriptyline demethylation. Clin Pharmacol Ther (1980) 0.77
Transient expression of c-fos during the development of the rat cerebral cortex. Brain Res Dev Brain Res (1991) 0.77
Sex differences in catechol contents in the olfactory bulb of control and unilaterally deprived rats. Eur J Neurosci (2007) 0.77
Hypotensive effect of naloxone on high blood pressure induced by stress in the rat. Life Sci (1987) 0.77
E- and Z-10-hydroxylation of nortriptyline by human liver microsomes--methods and characterization. Drug Metab Dispos (1983) 0.77
Experimental brain glioma: growth arrest and destruction by a blood-group-related tetrasaccharide. J Neuropathol Exp Neurol (1996) 0.77
Stimulus-specific hierarchy of enhancer elements within the rat prodynorphin promoter. J Neurochem (1998) 0.76
Metamizol potentiates morphine effects on visceral pain and evoked c-Fos immunoreactivity in spinal cord. Eur J Pharmacol (1998) 0.76
Locomotor activation induced in rodent by substance P and analogues. Blockade of the effect of substance P by met-enkephalin antiserum. Neuropharmacology (1984) 0.76
Narine occlusion decreases basal levels of Fos protein in the cerebral cortex of the lizard Podarcis hispanica. Neuroscience (1992) 0.76
Analgesic activity of substance P in rats: apparent mediation by met-enkephalin release. Life Sci (1982) 0.76
Fos-like expression and nuclear size in osmotically stimulated supraoptic nucleus neurons. Neuroscience (1992) 0.76
Induction of glycerol phosphate dehydrogenase gene expression during seizure and analgesia. J Neurochem (2000) 0.76
Expression of the bovine striatal D2 receptor, but not the D1 receptor, in bovine adrenal medulla. Mol Pharmacol (1995) 0.76
Nuclear Fos domains in transcriptionally activated supraoptic nucleus neurons. Neuroscience (1993) 0.76