Published in J Biol Chem on May 05, 1993
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J Cell Biol (1994) 2.69
Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane. Mol Biol Cell (2006) 2.27
Regulation of glucose transport by insulin: traffic control of GLUT4. Nat Rev Mol Cell Biol (2012) 2.18
Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160. Mol Biol Cell (2004) 2.09
A double leucine within the GLUT4 glucose transporter COOH-terminal domain functions as an endocytosis signal. J Cell Biol (1994) 2.08
Insulin signaling and the regulation of glucose transport. Mol Med (2006) 1.99
Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes. Mol Cell Biol (1997) 1.85
GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes. Mol Biol Cell (2003) 1.83
GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps. Mol Biol Cell (2002) 1.82
gp160, a tissue-specific marker for insulin-activated glucose transport. Proc Natl Acad Sci U S A (1994) 1.63
Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes. Mol Cell Biol (2007) 1.50
Actin filaments play a critical role in insulin-induced exocytotic recruitment but not in endocytosis of GLUT4 in isolated rat adipocytes. Biochem J (2000) 1.44
GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin. EMBO J (2006) 1.42
Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues. J Biol Chem (2004) 1.42
Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin. Proc Natl Acad Sci U S A (1995) 1.40
Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein. Proc Natl Acad Sci U S A (2001) 1.31
Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells. Biochem J (1996) 1.19
The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation. Mol Biol Cell (1999) 1.18
GLUT4 and transferrin receptor are differentially sorted along the endocytic pathway in CHO cells. J Cell Biol (1998) 1.13
Comparison of glucose-transporter-containing vesicles from rat fat and muscle tissues: evidence for a unique endosomal compartment. Biochem J (1995) 1.11
Insulin stimulation of glucose transport activity in rat skeletal muscle: increase in cell surface GLUT4 as assessed by photolabelling. Biochem J (1994) 1.08
Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells. FASEB J (2006) 1.06
G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane. Mol Cell Biol (2001) 1.04
Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle. Mol Cell Biol (1994) 1.03
Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Mol Biol Cell (2013) 0.99
Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions. Mutat Res (2006) 0.96
GLUT4 vesicle trafficking in rat adipocytes after ethanol feeding: regulation by heterotrimeric G-proteins. Biochem J (2001) 0.90
Reciprocal regulation of endocytosis and metabolism. Cold Spring Harb Perspect Biol (2014) 0.89
Insulin resistance and the disruption of Glut4 trafficking in skeletal muscle. J Clin Invest (2001) 0.83
Failure of insulin-regulated recruitment of the glucose transporter GLUT4 in cardiac muscle of obese Zucker rats is associated with alterations of small-molecular-mass GTP-binding proteins. Biochem J (1995) 0.82
Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. Diabetologia (2009) 0.82
The NMR structure of the TC10- and Cdc42-interacting domain of CIP4. J Biomol NMR (2009) 0.78
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Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event. Cell Signal (2015) 0.75
Membrane Cholesterol in Skeletal Muscle: A Novel Player in Excitation-Contraction Coupling and Insulin Resistance. J Diabetes Res (2017) 0.75
Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (1998) 1.83
ADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1. J Biol Chem (1999) 1.53
Insulin regulation of hexose transport in mouse 3T3-L1 cells expressing the human HepG2 glucose transporter. J Biol Chem (1990) 1.37
Exofacial epitope-tagged glucose transporter chimeras reveal COOH-terminal sequences governing cellular localization. J Cell Biol (1993) 1.30
Complex regulation of simple sugar transport in insulin-responsive cells. Trends Biochem Sci (1992) 1.20
A role for phospholipase D in GLUT4 glucose transporter translocation. J Biol Chem (2000) 1.15
Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes. J Biol Chem (2000) 1.10
Suppressed intrinsic catalytic activity of GLUT1 glucose transporters in insulin-sensitive 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1991) 1.09
Evidence that functional erythrocyte-type glucose transporters are oligomers. J Biol Chem (1991) 1.08
Protein synthesis inhibitors activate glucose transport without increasing plasma membrane glucose transporters in 3T3-L1 adipocytes. J Biol Chem (1991) 1.06
G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane. Mol Cell Biol (2001) 1.04
Insulin action on activity and cell surface disposition of human HepG2 glucose transporters expressed in Chinese hamster ovary cells. J Biol Chem (1990) 0.98
Evidence that erythroid-type glucose transporter intrinsic activity is modulated by cadmium treatment of mouse 3T3-L1 cells. J Biol Chem (1991) 0.93
Pericentriolar targeting of GDP-dissociation inhibitor isoform 2. Eur J Cell Biol (1995) 0.87