Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 8505316)

Published in J Biol Chem on June 05, 1993

Authors

R J Kaufman1, P Murtha-Riel, D D Pittman, M V Davies

Author Affiliations

1: Genetics Institute, Cambridge, Massachusetts 02140.

Articles by these authors

Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo. J Virol (1989) 7.01

The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs. Mol Cell Biol (1989) 4.81

Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature (1984) 4.19

Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells. EMBO J (1987) 2.35

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus. Nucleic Acids Res (1991) 2.29

Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif. EMBO J (1990) 2.12

Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J Biol Chem (1988) 1.96

GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Growth Factors (2001) 1.88

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity. Proc Natl Acad Sci U S A (1986) 1.82

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR. Proc Natl Acad Sci U S A (1994) 1.80

Complete cDNA and derived amino acid sequence of human factor V. Proc Natl Acad Sci U S A (1987) 1.75

Twenty years follow-up of patients with inoperable cancer of the prostate (stage C) treated by radiotherapy: report of a national cooperative study. Int J Radiat Oncol Biol Phys (1993) 1.46

The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers. Cell (1988) 1.44

Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells. Mol Cell Biol (1989) 1.36

Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy. J Gene Med (2001) 1.30

Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis. J Biol Chem (1993) 1.29

The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII. J Biol Chem (1991) 1.21

Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis. J Biol Chem (1995) 1.18

Stimulation of protein synthesis in COS cells transfected with variants of the alpha-subunit of initiation factor eIF-2. J Biol Chem (1992) 1.16

The binding of 35S-labeled recombinant factor VIII to activated and unactivated human platelets. J Biol Chem (1988) 1.15

Depletion of manganese within the secretory pathway inhibits O-linked glycosylation in mammalian cells. Biochemistry (1994) 1.12

Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Gene Ther (2003) 1.02

A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein-13 adenoviral gene therapy. J Neurosurg (2001) 1.01

Identification of individual tyrosine sulfation sites within factor VIII required for optimal activity and efficient thrombin cleavage. J Biol Chem (1994) 1.01

Biological regulation of factor VIII activity. Annu Rev Med (1992) 0.99

In vivo endochondral bone formation using a bone morphogenetic protein 2 adenoviral vector. Hum Gene Ther (1999) 0.98

Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent. J Neurosurg (2000) 0.95

Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation. Mol Cell Biol (1994) 0.94

Induction of a secreted protein by the myxoid liposarcoma oncogene. Proc Natl Acad Sci U S A (1999) 0.91

Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model. J Orthop Res (2004) 0.90

A 110-amino acid region within the A1-domain of coagulation factor VIII inhibits secretion from mammalian cells. J Biol Chem (1995) 0.89

The training of radiotherapists in the United States. Int J Radiat Oncol Biol Phys (1980) 0.89

Percutaneous spinal fusion using bone morphogenetic protein-2 gene therapy. J Neurosurg (1999) 0.87

The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets. J Biol Chem (1991) 0.85

Morphologic analysis of BMP-9 gene therapy-induced osteogenesis. Hum Gene Ther (2001) 0.82

Cloning and expression in COS-1 cells of a full-length cDNA encoding human coagulation factor X. Gene (1991) 0.82

The factor V B-domain provides two functions to facilitate thrombin cleavage and release of the light chain. Blood (1995) 0.79

Molecular cloning of a cDNA encoding human antihaemophilic factor. 1984. Biotechnology (1992) 0.77

Respiratory Competence in the Diagnosis of Gene-Controlled Phenotypes in Saccharomyces. Science (1957) 0.77

Radiation oncology: postgraduate medical education in the United States, 1988. Int J Radiat Oncol Biol Phys (1989) 0.75

The 1982 status of training of therapeutic radiologists in the United States. Int J Radiat Oncol Biol Phys (1983) 0.75

Postgraduate training in radiation oncology in the United States, 1986. Int J Radiat Oncol Biol Phys (1987) 0.75

Training in therapeutic radiology in the United States, 1984. Int J Radiat Oncol Biol Phys (1985) 0.75

[Results of twenty year follow-up of patients with inoperable prostate cancer (stage C) treated by radiotherapy. Report of a national multicenter study]. Bull Acad Natl Med (1993) 0.75