Published in Antimicrob Agents Chemother on September 01, 1995
Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages. PLoS Pathog (2011) 1.99
Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis. Antimicrob Agents Chemother (2012) 1.63
New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development. Antimicrob Agents Chemother (2008) 1.50
Use of Mono Mac 6 human monocytic cell line and J774 murine macrophage cell line in parallel antimycobacterial drug studies. Antimicrob Agents Chemother (1996) 1.39
Susceptibility testing of Mycobacterium avium complex isolates. Antimicrob Agents Chemother (1996) 1.22
Evaluation of rifapentine in long-term treatment regimens for tuberculosis in mice. Antimicrob Agents Chemother (1999) 1.11
Single-dose intrapulmonary pharmacokinetics of rifapentine in normal subjects. Antimicrob Agents Chemother (2000) 1.03
Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis. Dis Model Mech (2015) 1.03
Analysis of rifapentine for preventive therapy in the Cornell mouse model of latent tuberculosis. Antimicrob Agents Chemother (1999) 1.01
Rifapentine is not more active than rifampin against chronic tuberculosis in guinea pigs. Antimicrob Agents Chemother (2012) 0.98
Development of rifapentine susceptibility tests for Mycobacterium tuberculosis. Antimicrob Agents Chemother (1999) 0.89
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment. J Theor Biol (2014) 0.87
Evaluation of rifalazil in a combination treatment regimen as an alternative to isoniazid-rifampin therapy in a mouse tuberculosis model. Antimicrob Agents Chemother (2000) 0.85
Pharmacokinetics of rifapentine in subjects seropositive for the human immunodeficiency virus: a phase I study. Antimicrob Agents Chemother (1999) 0.84
A multi-scale approach to designing therapeutics for tuberculosis. Integr Biol (Camb) (2015) 0.82
Pulsed-exposure and postantibiotic leukocyte enhancement effects of amikacin, clarithromycin, clofazimine, and rifampin against intracellular Mycobacterium avium. Antimicrob Agents Chemother (1998) 0.78
Activities of poloxamer CRL-1072 against Mycobacterium avium in macrophage culture and in mice. Antimicrob Agents Chemother (1999) 0.78
Drug effects on intracellular mycobacteria determined by mass spectrometric analysis of the Na(+)-to-K+ ratios of individual bacterial organisms. Antimicrob Agents Chemother (1996) 0.76
De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro. Antimicrob Agents Chemother (2016) 0.75
Bactericidal activity in vitro of various rifamycins against Mycobacterium avium and Mycobacterium tuberculosis. Am Rev Respir Dis (1990) 2.24
Effectiveness of rifampin, rifabutin, and rifapentine for preventive therapy of tuberculosis in mice. Am Rev Respir Dis (1993) 2.07
Inhibitory and bactericidal activities of levofloxacin against Mycobacterium tuberculosis in vitro and in human macrophages. Antimicrob Agents Chemother (1994) 1.60
Activity in vitro of rifabutin, FCE 22807, rifapentine, and rifampin against Mycobacterium microti and M. tuberculosis and their penetration into mouse peritoneal macrophages. Am Rev Respir Dis (1992) 1.56
Uptake and activity of rifapentine in human peritoneal macrophages and polymorphonuclear leukocytes. Eur J Clin Microbiol (1987) 1.55
Mean cell volume of human blood leucocytes and resident and activated murine macrophages. J Immunol Methods (1990) 1.48
Antibacterial activity of DL 473, a new semisynthetic rifamycin derivative. J Antibiot (Tokyo) (1981) 1.42
In vitro observations on the suitability of new rifamycins for the intermittent chemotherapy of tuberculosis. Tubercle (1987) 1.30
In vitro properties of rifapentine (MDL473) relevant to its use in intermittent chemotherapy of tuberculosis. Tubercle (1987) 1.19
Comparison of the sensitivity of mycobacteria to the cyclopentyl rifamycin DL473 and rifampicin. J Antimicrob Chemother (1982) 1.14
Pharmacokinetics of rifapentine, a new long lasting rifamycin, in the rat, the mouse and the rabbit. J Antibiot (Tokyo) (1984) 1.12
Antibacterial activity in serum and urine following oral administration in man of DL473 (a cyclopentyl derivative of rifampicin) [proceedings]. Br J Clin Pharmacol (1978) 1.09
Activity of two long-acting rifamycins, rifapentine and FCE 22807, in experimental murine tuberculosis. Tuber Lung Dis (1992) 1.04
Effects of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium. Antimicrob Agents Chemother (1994) 1.02
[Activity of intermittently administered rifampicin and cyclopentyl rifamycin (or DL473) on experimental tuberculosis in the mouse]. Rev Fr Mal Respir (1983) 1.00
Comparative uptake of rifampicin and rifapentine (DL473) by human neutrophils. J Antimicrob Chemother (1984) 0.92
[In-vitro antimycobacterial activity of rifapentine (comparison with rifampicin)]. Kekkaku (1986) 0.88
Evaluation of the BACTEC radiometric method for recovery of mycobacteria and drug susceptibility testing of Mycobacterium tuberculosis from acid-fast smear-positive specimens. J Clin Microbiol (1983) 10.49
Collaborative feasibility study of a biphasic system (Roche Septi-Chek AFB) for rapid detection and isolation of mycobacteria. J Clin Microbiol (1991) 4.91
Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother (1997) 3.75
Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions. Clin Pharmacol Ther (1999) 2.33
pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada. Antimicrob Agents Chemother (2000) 2.10
Strategy to detect and identify Bartonella species in routine clinical laboratory yields Bartonella henselae from human immunodeficiency virus-positive patient and unique Bartonella strain from his cat. J Clin Microbiol (1995) 2.06
Immunologic diagnosis of tuberculosis: a review. Tuber Lung Dis (2000) 1.90
An inequality among determinants. Proc Natl Acad Sci U S A (1975) 1.74
Frequencies of CD4+ T cells reactive with Plasmodium chabaudi chabaudi: distinct response kinetics for cells with Th1 and Th2 characteristics during infection. Int Immunol (1989) 1.68
A randomized trial of clarithromycin as prophylaxis against disseminated Mycobacterium avium complex infection in patients with advanced acquired immunodeficiency syndrome. N Engl J Med (1996) 1.64
Qualitative and quantitative analysis of the binding of GII.4 norovirus variants onto human blood group antigens. J Virol (2011) 1.61
Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. J Infect Dis (1996) 1.61
Inhibitory and bactericidal activities of levofloxacin against Mycobacterium tuberculosis in vitro and in human macrophages. Antimicrob Agents Chemother (1994) 1.60
Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages. Int J Tuberc Lung Dis (2000) 1.58
Gen-probe test should not be considered final in Mycobacterium tuberculosis identification. J Clin Microbiol (1989) 1.58
Gastric mucosa during treatment with lansoprazole: Helicobacter pylori is a risk factor for argyrophil cell hyperplasia. Gastroenterology (1997) 1.56
Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J Clin Invest (1993) 1.55
MICs and MBCs of clarithromycin against Mycobacterium avium within human macrophages. Antimicrob Agents Chemother (1993) 1.50
The ecology of social relationships in housing for the elderly. Gerontologist (1968) 1.45
24 hour intragastric acidity and single night-time dose of three H-2-blockers. Lancet (1983) 1.41
Dynamics of P. falciparum gametocytemia in symptomatic patients in an area of intense perennial transmission in Tanzania. Am J Trop Med Hyg (2001) 1.34
Large artery remodeling during aging: biaxial passive and active stiffness. Hypertension (1998) 1.33
[Healing rates following omeprazole and ranitidine treatment of gastric ulcer. Results of a German multicenter study]. Dtsch Med Wochenschr (1985) 1.31
Comparison of three methods for recovery of Mycobacterium avium complex from blood specimens. J Clin Microbiol (1988) 1.31
Expression of peroxidase-dependent iodination by macrophages ingesting neutrophil debris. J Reticuloendothel Soc (1980) 1.26
Modification of osteoarthritis by pulsed electromagnetic field--a morphological study. Osteoarthritis Cartilage (2003) 1.23
Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis. Exp Cell Res (1999) 1.23
Treatment of neuroendocrine GEP tumours with somatostatin analogues: a review. Digestion (2000) 1.14
Effect of repeated, once daily, oral omeprazole on gastric secretion. Lancet (1983) 1.12
Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors. Oncogene (1999) 1.10
Evaluation of the VA's Pilot Program in Institutional Reorganization toward Primary and Ambulatory Care: Part I, Changes in process and outcomes of care. Acad Med (1996) 1.10
Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum. Mol Immunol (1995) 1.09
Antimycobacterial agent based on mRNA encoding human beta-defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis. Infect Immun (2001) 1.08
Increasing the impact of quality improvement on health: an expert panel method for setting institutional priorities. Jt Comm J Qual Improv (1995) 1.07
HCO 3 -stimulated ATPase from mammalian pancreas. Properties and its arrangement with other enzyme activities. Biochim Biophys Acta (1972) 1.07
Pulsed electromagnetic fields simultaneously induce osteogenesis and upregulate transcription of bone morphogenetic proteins 2 and 4 in rat osteoblasts in vitro. Biochem Biophys Res Commun (1998) 1.06
Low serum levels of oral antimycobacterial agents in patients with disseminated Mycobacterium avium complex disease. J Infect Dis (1993) 1.06
Human fat cell adenylate cyclase: regional differences in adrenaline responsiveness. Eur J Clin Invest (1977) 1.06
Pulsed electromagnetic field stimulation of MG63 osteoblast-like cells affects differentiation and local factor production. J Orthop Res (2000) 1.05
Human gastric acid secretion following repeated doses of AG-1749. Aliment Pharmacol Ther (1989) 1.03
An accelerated vaccine schedule with a poly-antigenic hepatitis C virus MVA-based candidate vaccine induces potent, long lasting and in vivo cross-reactive T cell responses. Vaccine (2007) 1.02
Effects of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium. Antimicrob Agents Chemother (1994) 1.02
Dose-related healing of duodenal ulcer with the proton pump inhibitor lansoprazole. Aliment Pharmacol Ther (1991) 1.01
Synthesis of ganglioside GD3 and its comparison with bovine GD3 with regard to oligodendrocyte apoptosis mitochondrial damage. Chemistry (2001) 1.01
Randomized, open-label trial of azithromycin plus ethambutol vs. clarithromycin plus ethambutol as therapy for Mycobacterium avium complex bacteremia in patients with human immunodeficiency virus infection. Veterans Affairs HIV Research Consortium. Clin Infect Dis (1998) 1.01
Analysis of beta-catenin gene mutations in pancreatic tumors. Digestion (2000) 1.01
A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints. J Biomol NMR (2008) 1.01
Alpha1-antitrypsin deficiency with M-like phenotype. J Med Genet (1977) 0.99
Identification of ethanol-intoxicated patients with minor head trauma requiring computed tomography scans. Acad Emerg Med (1995) 0.99
Inhibition of intracellular growth of Mycobacterium avium by one pulsed exposure of infected macrophages to clarithromycin. Antimicrob Agents Chemother (1993) 0.98
Proposed recommendations for the management of HIV post-exposure prophylaxis after sexual, injecting drug or other exposures in Europe. Euro Surveill (2004) 0.97
Should we routinely screen for cytomegalovirus antibody during pregnancy? Intervirology (1998) 0.97
Forskolin induced chloride secretion across the isolated mucosa of rat colon descendens. Naunyn Schmiedebergs Arch Pharmacol (1983) 0.97
Requirement for omega and (omega;-1)-hydroxylations of fatty acids by human cytochromes P450 2E1 and 4A11. J Lipid Res (1999) 0.97
[Investigations on the length of action of ranitidine (author's transl)]. Dtsch Med Wochenschr (1980) 0.96
High-resolution three-dimensional tomographic diffractive microscopy of transparent inorganic and biological samples. Opt Lett (2009) 0.95
Management of nonfunctioning islet cell carcinomas. World J Surg (2000) 0.94
Immunological and biological properties of Bet v 4, a novel birch pollen allergen with two EF-hand calcium-binding domains. J Biol Chem (1997) 0.94
Interferon-inducible Mx proteins in fish. Immunol Rev (1998) 0.93
Comparative effects of famotidine and cimetidine on antipyrine kinetics in healthy volunteers. Br J Clin Pharmacol (1984) 0.93
The presence of a HCO 3 ATPase in glandula submandibularis of rabbit. Pflugers Arch (1972) 0.93
Nitric oxide inhibits execution of apoptosis at two distinct ATP-dependent steps upstream and downstream of mitochondrial cytochrome c release. Biochem Biophys Res Commun (1999) 0.92
Selective inhibition of endothelium-dependent dilation in resistance-sized vessels in vivo. Am J Physiol (1987) 0.92
Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase. J Clin Invest (1979) 0.92
High levels of circulating adrenomedullin in severe illness: correlation with C-reactive protein and evidence against the adrenal medulla as site of origin. Exp Clin Endocrinol Diabetes (1997) 0.92
Catecholamine-sensitive adenylate cyclase of human fat cell ghosts. Characteristics of the GMP(PNP)-liganded state. Clin Chim Acta (1976) 0.91
Cytochrome P-450 2E1 activity and oxidative stress in alcoholic patients. Alcohol Alcohol (2000) 0.91
Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis. Int J Pharm (2007) 0.91
Higher frequency of DPC4/Smad4 alterations in pancreatic cancer cell lines than in primary pancreatic adenocarcinomas. Cancer Lett (1999) 0.91
Topographical studies on histamine- and adrenaline-sensitive adenylate cyclases in gastric and duodenal mucosa of human beings. Digestion (1977) 0.91
Dose-range finding study with the proton pump inhibitor pantoprazole in acute duodenal ulcer patients. Z Gastroenterol (1992) 0.90
The presence of a HCO 3 - -ATPase in pancreatic tissue. Biochim Biophys Acta (1972) 0.90
Accumulation of clarithromycin in macrophages infected with Mycobacterium avium. Pharmacotherapy (1994) 0.90
Effect of egg yolk on growth of Mycobacterium tuberculosis in 7H12 liquid medium. J Clin Microbiol (1988) 0.90
On-demand treatment of gastro-oesophageal reflux symptoms: a comparison of ranitidine 75 mg with cimetidine 200 mg or placebo. Aliment Pharmacol Ther (1998) 0.90
Omeprazole heals duodenal, but not gastric ulcers more rapidly than ranitidine. Results of two German multicentre trials. Hepatogastroenterology (1985) 0.90
Prevention of aspirin-induced drop in gastric potential difference with 16, 16-dimethyl-prostaglandin E2. Lancet (1981) 0.90
[Short-term therapy of duodenal ulcer with omeprazole and ranitidine. Results of a German multicenter study]. Dtsch Med Wochenschr (1985) 0.90
The alpha 6-integrin receptor in pancreatic carcinoma. Gastroenterology (1995) 0.89
Feasibility and effectiveness of school-based relaxation in lowering blood pressure. Health Psychol (1987) 0.89
[Quality of life of children and adolescents with psychiatric disorders. Results of the 1st multicenter study with an inventory to assess the quality of life in children and adolescents]. Z Kinder Jugendpsychiatr Psychother (2003) 0.88
In vivo interactions between H2-receptor antagonists and ethanol metabolism in man and in rats. Hepatology (1985) 0.88
Activation of the Ca2+ "receptor" on the osteoclast by Ni2+ elicits cytosolic Ca2+ signals: evidence for receptor activation and inactivation, intracellular Ca2+ redistribution, and divalent cation modulation. J Cell Physiol (1993) 0.88
Effect of faradic products on direct current-stimulated calvarial organ culture calcium levels. Biochem Biophys Res Commun (1999) 0.88
Long-term functional status and mortality of elderly patients with severe closed head injuries. J Trauma (1996) 0.87
Properties of a synthetic plasma membrane marker: fluorescent-mercury-dextran. J Membr Biol (1973) 0.87
ZBP-89, a Krüppel-type zinc finger protein, inhibits cell proliferation. Biochem Biophys Res Commun (1997) 0.87
Activation of human adenylate cyclase in the upper gastrointestinal tract by vasoactive intestinal polypeptide. Gastroenterology (1978) 0.87
[Gastrointestinal tolerance of 30 mg versus 300 mg acetylsalicylic acid daily. An endoscopically controlled double-blind study of healthy subjects]. Med Klin (Munich) (1990) 0.87
Prospective analysis of human cytomegalovirus DNAemia and specific CD8+ T cell responses in lung transplant recipients. Am J Transplant (2012) 0.86
Adenylate cyclase of human fat cell ghosts. Stimulation of enzyme activity by parathyroid hormone. J Clin Invest (1977) 0.86
Catecholamine-sensitive adenylate cyclase of human fat cell ghosts: a comparative study using different beta-adrenergic agents. Metabolism (1977) 0.86
Human colonic adenylate cyclase: effects of bile acids. Eur J Clin Invest (1978) 0.86
Nocturnal acid suppression with a new H2 receptor antagonist--nizatidine. Hepatogastroenterology (1986) 0.86
Enolases are highly conserved fungal allergens. Int Arch Allergy Immunol (1997) 0.85
Limiting dilution analysis of the T cell response to Plasmodium chabaudi chabaudi in mice. Parasite Immunol (1989) 0.85
Effects of pulsed electromagnetic fields on bone healing in a rabbit tibial osteotomy model. J Orthop Trauma (2000) 0.85