A P Davenport

Author PubWeight™ 93.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation 2002 4.43
2 The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol 2013 2.48
3 Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol 2000 1.78
4 Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium. Circ Res 1993 1.56
5 ETA receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro. Br J Pharmacol 1995 1.48
6 [(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br J Pharmacol 2001 1.40
7 Chemokine receptor CCR5: from AIDS to atherosclerosis. Br J Pharmacol 2011 1.29
8 Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ETA and ETB in human kidney. Kidney Int 1993 1.22
9 Characterization of two new ETB selective radioligands, [125I]-BQ3020 and [125I]-[Ala1,3,11,15]ET-1 in human heart. Br J Pharmacol 1992 1.17
10 Effects of an ET1-receptor antagonist, FR139317, on regional haemodynamic responses to endothelin-1 and [Ala11,15]Ac-endothelin-1 (6-21) in conscious rats. Br J Pharmacol 1994 1.15
11 Endothelin-1 mRNA is widely expressed in porcine and human tissues. J Clin Invest 1990 1.13
12 [125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Br J Pharmacol 2001 1.11
13 Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol 2007 1.11
14 Depressor and regionally-selective vasodilator effects of human and rat urotensin II in conscious rats. Br J Pharmacol 2001 1.10
15 Endothelin peptide and receptors in human atherosclerotic coronary artery and aorta. Circ Res 1996 1.04
16 Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro. Br J Pharmacol 1994 1.01
17 Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1. Am J Physiol Regul Integr Comp Physiol 2001 1.00
18 Presence of messenger ribonucleic acid for endothelin-1, endothelin-2, and endothelin-3 in human endometrium and a change in the ratio of ETA and ETB receptor subtype across the menstrual cycle. J Clin Endocrinol Metab 1992 1.00
19 Secretory pathways in endothelin synthesis. Br J Pharmacol 1999 0.98
20 Human endothelial cell storage granules: a novel intracellular site for isoforms of the endothelin-converting enzyme. Circ Res 1998 0.97
21 Anatomical localization and pharmacological activity of mature endothelins and their precursors in human vascular tissue. J Hypertens 1992 0.95
22 Evidence using immunoelectron microscopy for regulated and constitutive pathways in the transport and release of endothelin. J Cardiovasc Pharmacol 1998 0.95
23 Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan. Br J Pharmacol 2001 0.93
24 Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. Br J Pharmacol 2009 0.93
25 Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis. Atherosclerosis 2009 0.93
26 Comparison of the vasoconstrictor effects of rizatriptan and sumatriptan in human isolated cranial arteries: immunohistological demonstration of the involvement of 5-HT1B-receptors. Br J Clin Pharmacol 1998 0.93
27 Endothelin receptors in human coronary artery and aorta. Br J Pharmacol 1996 0.92
28 Endothelin converting enzyme (ECE) activity in human vascular smooth muscle. Br J Pharmacol 1997 0.90
29 Secretion of endothelin-1 and endothelin-3 by human cultured vascular smooth muscle cells. Br J Pharmacol 1995 0.89
30 Characterization of the endothelin receptor selective agonist, BQ3020 and antagonists BQ123, FR139317, BQ788, 50235, Ro462005 and bosentan in the heart. Br J Pharmacol 1996 0.89
31 Physiological antagonism of endothelin-1 in human conductance and resistance coronary artery. Br J Pharmacol 2001 0.89
32 Endothelin receptor subtypes and their functional relevance in human small coronary arteries. Br J Pharmacol 1998 0.89
33 The increase in human plasma immunoreactive endothelin but not big endothelin-1 or its C-terminal fragment induced by systemic administration of the endothelin antagonist TAK-044. Br J Pharmacol 1996 0.89
34 Alternatively spliced mRNAs for human endothelin-2 and their tissue distribution. Biochem Biophys Res Commun 1993 0.88
35 Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol 2010 0.88
36 Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res 1999 0.88
37 Endothelin receptor antagonism in patients with chronic heart failure. Cardiovasc Res 2000 0.87
38 Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated. J Cardiovasc Pharmacol 1993 0.87
39 Blockade and reversal of endothelin-induced constriction in pial arteries from human brain. Stroke 1999 0.87
40 A quantitative 'in-situ' hybridization method using computer-assisted image analysis. Validation and measurement of atrial-natriuretic-factor mRNA in the rat heart. Biochem J 1989 0.87
41 Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system. Br J Pharmacol 2001 0.87
42 Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin-1, to distinguish between these agonists in binding experiments. Br J Pharmacol 1996 0.86
43 Selectivity of [125I]-PD151242 for human, rat and porcine endothelin ETA receptors in the heart. Br J Pharmacol 1995 0.86
44 Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro. Br J Pharmacol 2001 0.86
45 Affinity and selectivity of PD156707, a novel nonpeptide endothelin antagonist, for human ET(A) and ET(B) receptors. J Pharmacol Exp Ther 1997 0.86
46 Expression of endothelin peptides and mRNA in the human heart. Clin Sci (Lond) 1996 0.85
47 Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. Br J Pharmacol 2014 0.85
48 Characterization of the binding of endothelin ETB selective ligands in human and rat heart. Br J Pharmacol 1996 0.85
49 Endothelin ETA receptor expression in human cerebrovascular smooth muscle cells. Br J Pharmacol 1995 0.85
50 Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system. Can J Physiol Pharmacol 2002 0.85
51 Localization of endothelin receptors in human uterus throughout the menstrual cycle. Mol Hum Reprod 1996 0.84
52 Localization of endothelin peptides in human kidney. Kidney Int 1996 0.84
53 Quantification of mRNA in human tissue using fluorescent nested reverse-transcriptase polymerase chain reaction. Anal Biochem 1994 0.84
54 Epidermal growth factor in human endometrium: proliferative effects in culture and immunocytochemical localization in normal and endometriotic tissues. Hum Reprod 1991 0.84
55 Endothelin receptor expression and pharmacology in human saphenous vein graft. Br J Pharmacol 1999 0.84
56 Endothelin expression in the uterus. J Steroid Biochem Mol Biol 1995 0.84
57 Characterization of endothelin receptors in human brain cortex, gliomas, and meningiomas. J Cardiovasc Pharmacol 1995 0.83
58 Endothelin: progress in pharmacology and physiology. Trends Pharmacol Sci 1993 0.83
59 Phosphoramidon inhibition of the in vivo conversion of big endothelin-1 to endothelin-1 in the human forearm. Br J Pharmacol 1995 0.83
60 Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707. Neurosurgery 1998 0.83
61 Relative contribution of endothelin A and endothelin B receptors to vasoconstriction in small arteries from human heart and brain. J Cardiovasc Pharmacol 1998 0.82
62 Differential distribution of endothelin receptor subtypes in placentae from normal and growth-restricted pregnancies. Placenta 1997 0.82
63 Human kidney: endothelin isoforms detected by HPLC with radioimmunoassay and receptor subtypes detected using ligands BQ123 and BQ3020. J Cardiovasc Pharmacol 1993 0.82
64 Effects of phosphoramidon and pepstatin A on the secretion of endothelin-1 and big endothelin-1 by human umbilical vein endothelial cells: measurement by two-site enzyme-linked immunosorbent assays. Clin Sci (Lond) 1994 0.82
65 Regulation of endothelin receptor expression in vascular smooth-muscle cells. J Cardiovasc Pharmacol 1995 0.81
66 Localization of immunoreactive endothelin and proendothelin in the human lung. Pulm Pharmacol 1992 0.81
67 Maternal dexamethasone increases endothelin-1 sensitivity and endothelin a receptor expression in ovine foetal placental arteries. Placenta 2003 0.81
68 Myricerone caffeoyl ester (50-235) is a non-peptide antagonist selective for human ETA receptors. J Hypertens 1994 0.81
69 Endothelin-A-receptors in human aorta and pulmonary arteries are downregulated in patients with cardiovascular disease: an adaptive response to increased levels of endothelin-1? J Cardiovasc Pharmacol 2000 0.81
70 Endothelin-like immunoreactivity in human endometrium. J Reprod Fertil 1992 0.81
71 ETA and ETB endothelin receptors in human myometrium characterized by the subtype selective ligands BQ123, BQ3020, FR139317 and PD151242. J Endocrinol 1995 0.81
72 Increased response to big endothelin-1 in atherosclerotic human coronary artery: functional evidence for up-regulation of endothelin-converting enzyme activity in disease. Br J Pharmacol 1998 0.80
73 Identification of endothelin-1, endothelin-2 and endothelin-3 in human endometrium. J Reprod Fertil 1993 0.80
74 Characterization of the snake venom ligand [125I]-DNP binding to natriuretic peptide receptor-A in human artery and potent DNP mediated vasodilatation. Br J Pharmacol 2006 0.80
75 No alteration in vasoconstrictor endothelin-B-receptor density or function in human coronary artery disease. J Cardiovasc Pharmacol 2000 0.79
76 The endothelin peptides ET-1, ET-2, ET-3 and sarafotoxin S6b are co-mitogenic with platelet-derived growth factor for vascular smooth muscle cells. Atherosclerosis 1990 0.79
77 Delineation of endothelin receptors in human left ventricular smooth-muscle cells. J Cardiovasc Pharmacol 1995 0.78
78 Endothelin-2 mRNA splice variants detected by RT-PCR in cultured human vascular smooth muscle and endothelial cells. J Cardiovasc Pharmacol 1993 0.78
79 Changes in ET(A)-, AT1- and AT2-receptors in the phenotypically transformed intimal smooth muscle layer of human atherosclerotic coronary arteries. J Cardiovasc Pharmacol 2000 0.78
80 Localization and endogenous concentration of endothelin-like immunoreactivity in human placenta. J Endocrinol 1991 0.78
81 Measurement of C-terminal fragment of big endothelin-1: a novel method for assessing the generation of endothelin-1 in humans. J Cardiovasc Pharmacol 1995 0.78
82 Endothelin peptide and converting enzymes in human endothelium. J Cardiovasc Pharmacol 1998 0.77
83 Novel nitric oxide donors reverse endothelin-1-mediated constriction in human blood vessels. J Cardiovasc Pharmacol 2000 0.77
84 PD156707: a potent antagonist of endothelin-1 in human diseased coronary arteries and vein grafts. J Cardiovasc Pharmacol 1998 0.77
85 Distribution of endothelin receptors in atherosclerotic human coronary arteries. J Cardiovasc Pharmacol 1995 0.77
86 Biogenic amines in the brain of the honeybee, Apis mellifera. Cell Tissue Res 1983 0.77
87 Syntheses of the first endothelin-A- and -B-selective radioligands for positron emission tomography. J Cardiovasc Pharmacol 2000 0.77
88 Endothelin and the human kidney: a potential target for new drugs. Nephrol Dial Transplant 1994 0.77
89 Comparative quantification of endothelin receptor mRNA in human kidney: new tools for direct investigation of human tissue. J Cardiovasc Pharmacol 1995 0.76
90 Atrial natriuretic factor mRNA and binding sites in the adrenal gland. Biochem J 1990 0.76
91 Characterization of endothelin receptors in the human pulmonary vasculature using bosentan, SB209670, and 97-139. J Cardiovasc Pharmacol 1995 0.76
92 In vitro enzymatic processing of radiolabelled big ET-1 in human kidney. Biochem Pharmacol 1998 0.76
93 Cerebellar neurons and glia respond differentially to endothelins and sarafotoxin S6b. Brain Res 1992 0.76
94 The haemodynamic effects of iodinated water soluble radiographic contrast media: a review. Eur J Radiol 1998 0.76
95 Characterization of peptide and nonpeptide antagonists in human kidney. J Cardiovasc Pharmacol 1995 0.76
96 Detection of endothelin receptors in human coronary artery vascular smooth muscle cells but not endothelial cells by using electron microscope autoradiography. J Cardiovasc Pharmacol 1997 0.76
97 Endothelin-1 stimulates prostaglandin F2 alpha release from human endometrium. Prostaglandins Leukot Essent Fatty Acids 1991 0.76
98 Characterization of site-directed antisera against endothelin-converting enzymes. J Cardiovasc Pharmacol 1998 0.75
99 Autoradiographic study of endothelin receptors in human cerebral arteries. J Cardiovasc Pharmacol 1995 0.75
100 Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--II. Differential localization of dopamine and cholecystokinin receptors. Neuroscience 1988 0.75
101 Tissue-specific modulation of endothelin receptors in a rat model of hypertension. J Cardiovasc Pharmacol 2000 0.75
102 Molecular aspects of atrial natriuretic factor physiology. Ann Acad Med Singapore 1991 0.75
103 Quantitative autoradiography reveals higher densities of specific calcitonin-gene-related peptide receptors in small intramyocardial compared with large epicardial coronary arteries. Clin Sci (Lond) 1993 0.75
104 Selective downregulation of ETA receptor mRNA in renal transplant recipients on cyclosporin A revealed by quantitative RT-PCR. Nephrol Dial Transplant 1996 0.75
105 Expression and characterization of the human endothelin-A-receptor in Pichia pastoris: influence of N-terminal epitope tags. J Cardiovasc Pharmacol 2000 0.75
106 Sex-related differences in the concentration of Met-enkephalin-like immunoreactivity in the nervous system of an insect, Schistocerca gregaria, revealed by radioimmunoassay. Brain Res 1986 0.75
107 Potency of PD155080, an orally active ETA receptor antagonist, determined for human endothelin receptors. J Cardiovasc Pharmacol 1995 0.75
108 Quantitative analysis of autoradiograms. Experientia Suppl 1989 0.75
109 Analysis of endogenous human endothelin peptides by high-performance liquid chromatography and mass spectrometry. J Cardiovasc Pharmacol 1995 0.75
110 The therapeutic potential of PD156707 and related butenolide endothelin antagonists. Expert Opin Investig Drugs 1999 0.75
111 Isolation of human cardiac endothelin receptors by a peptide-receptor mobility shift assay. Clin Sci (Lond) 1993 0.75