1
|
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers.
|
Cell
|
1996
|
15.19
|
2
|
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase.
|
Biochemistry
|
1996
|
2.46
|
3
|
Muir-Torre-like syndrome in Fhit-deficient mice.
|
Proc Natl Acad Sci U S A
|
2000
|
2.15
|
4
|
Structure and expression of the human FHIT gene in normal and tumor cells.
|
Cancer Res
|
1997
|
1.76
|
5
|
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
|
Proc Natl Acad Sci U S A
|
1998
|
1.68
|
6
|
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.
|
Proc Natl Acad Sci U S A
|
1998
|
1.32
|
7
|
Absence or reduction of Fhit expression in most clear cell renal carcinomas.
|
Cancer Res
|
1998
|
1.18
|
8
|
The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B.
|
Biochim Biophys Acta
|
1997
|
1.07
|
9
|
Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression.
|
Cancer Res
|
2000
|
1.04
|
10
|
The role of deletions at the FRA3B/FHIT locus in carcinogenesis.
|
Recent Results Cancer Res
|
1998
|
0.86
|
11
|
Influence of a nonfragile FHIT transgene on murine tumor susceptibility.
|
Cytogenet Genome Res
|
2007
|
0.76
|