PubRank

M Pfahl

Author PubWeight™ 103.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature 1992 4.44
2 How lac repressor binds to DNA. Nature 1972 3.72
3 Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 1992 3.39
4 A new retinoic acid receptor identified from a hepatocellular carcinoma. Nature 1988 3.33
5 "Second" and "third operator" of the lac operon: an investigation of their role in the regulatory mechanism. J Mol Biol 1979 2.56
6 Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity. Nature 1989 2.23
7 A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library. Science 1987 2.21
8 COUP orphan receptors are negative regulators of retinoic acid response pathways. Mol Cell Biol 1992 1.94
9 An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element. J Biol Chem 1996 1.92
10 Retinoids selective for retinoid X receptor response pathways. Science 1992 1.91
11 A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol 1994 1.86
12 Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region. Cell 1982 1.75
13 Repressors. Adv Protein Chem 1976 1.51
14 Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol 1991 1.44
15 A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter. Mol Endocrinol 1990 1.43
16 Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities. Mol Cell Biol 1991 1.41
17 A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature 1994 1.31
18 Characteristics of tight binding repressors of the lac operon. J Mol Biol 1981 1.29
19 Genetic analysis of the active sites of lac repressor. Genetics 1974 1.27
20 DNA binding properties of glucocorticosteroid receptors bound to the steroid antagonist RU-486. EMBO J 1984 1.27
21 Retinoic acid receptors and retinoid X receptor-alpha down-regulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity. Mol Endocrinol 1993 1.24
22 Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching. Mol Cell Biol 1993 1.22
23 Nuclear retinoic acid receptors: cloning, analysis, and function. Methods Enzymol 1990 1.17
24 General features of steroid resistance on lymphoid cell lines. Mol Cell Endocrinol 1978 1.16
25 The human estrogen receptor has transcriptional activator and repressor functions in the absence of ligand. New Biol 1990 1.16
26 RAR gamma 2 expression is regulated through a retinoic acid response element embedded in Sp1 sites. Mol Cell Biol 1992 1.15
27 Antagonism between retinoic acid receptors. Mol Cell Biol 1991 1.14
28 Genetic map of the lactose repressor gene (i) of Escherichia coli. Genetics 1972 1.13
29 lac Repressor-operator interaction. Analysis of the X86 repressor mutant. J Mol Biol 1976 1.13
30 4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors. J Biol Chem 1996 1.07
31 Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor. Mol Cell Biol 1994 1.06
32 Correlation of glucocorticoid receptor binding sites on MMTV proviral DNA with hormone inducible transcription. Science 1983 1.06
33 Effect of DNA denaturants on the lac repressor-operator interaction. Biochim Biophys Acta 1978 1.05
34 Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation. Mol Cell Biol 1997 1.04
35 A retinoic acid response element from the rat CRBPI promoter is activated by an RAR/RXR heterodimer. Biochem Biophys Res Commun 1992 1.03
36 Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities. Mol Endocrinol 1992 1.02
37 Inhibition of estrogen receptor activity by the tumor promoter 12-O-tetradeconylphorbol-13-acetate: a molecular analysis. Mol Endocrinol 1991 1.02
38 TOR: a new orphan receptor expressed in the thymus that can modulate retinoid and thyroid hormone signals. Mol Endocrinol 1995 1.01
39 Retinoic acid affects the expression of nuclear retinoic acid receptors in tissues of retinol-deficient rats. Proc Natl Acad Sci U S A 1991 1.01
40 Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo. Nat Med 1997 0.99
41 Interaction of glucocorticoid receptors from lymphoid cell lines with their nuclear acceptor sites. Mol Cell Endocrinol 1978 0.99
42 DNA bending by retinoid X receptor-containing retinoid and thyroid hormone receptor complexes. Mol Cell Biol 1993 0.98
43 Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity. J Med Chem 1995 0.95
44 Hetero- and homodimeric receptors in thyroid hormone and vitamin A action. Receptor 1993 0.94
45 Genomic organization of the retinoic acid receptor gamma gene. Nucleic Acids Res 1991 0.93
46 A specific defect in the retinoic acid response associated with human lung cancer cell lines. Cancer Res 1994 0.92
47 Ligand-binding domain of thyroid hormone receptors modulates DNA binding and determines their bifunctional roles. New Biol 1991 0.92
48 An evolutionary conserved COUP-TF binding element in a neural-specific gene and COUP-TF expression patterns support a major role for COUP-TF in neural development. Mol Endocrinol 1994 0.92
49 V-erbA requires auxiliary proteins for dominant negative activity. Oncogene 1993 0.92
50 A synthetic retinoid antagonist inhibits the human immunodeficiency virus type 1 promoter. Proc Natl Acad Sci U S A 1994 0.91
51 DNA binding and dimerization determinants for thyroid hormone receptor alpha and its interaction with a nuclear protein. Mol Endocrinol 1991 0.90
52 Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro. Blood 1996 0.89
53 6'-substituted naphthalene-2-carboxylic acid analogs, a new class of retinoic acid receptor subtype-specific ligands. Biochem Biophys Res Commun 1991 0.89
54 Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases. Cancer Res 2001 0.88
55 Apoptosis induction and potent antiestrogen receptor-negative breast cancer activity in vivo by a retinoid antagonist. Cancer Res 1998 0.88
56 The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal. Mol Cell Biol 1996 0.88
57 Regulatory functions of a non-ligand-binding thyroid hormone receptor isoform. Cell Regul 1991 0.88
58 Isolation of pseudorevertants of lac oc mutants: selection system for superoperator mutations. J Bacteriol 1976 0.87
59 Analysis of steroid resistance in lymphoid cell hybrids. Somatic Cell Genet 1980 0.86
60 Identification of retinoids with nuclear receptor subtype-selective activities. Cancer Res 1991 0.86
61 Interaction of tight binding repressors with lac operators. An analysis by DNA-footprinting. J Mol Biol 1984 0.84
62 Retinoic acid receptor gamma1 (RARgamma1) levels control RARbeta2 expression in SK-N-BE2(c) neuroblastoma cells and regulate a differentiation-apoptosis switch. Mol Cell Biol 1998 0.84
63 The orphan receptor TAK1 acts as a repressor of RAR-, RXR- and T3R-mediated signaling pathways. Biochem Biophys Res Commun 1995 0.84
64 Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity. J Med Chem 1993 0.83
65 A selective retinoid with high activity against an androgen-resistant prostate cancer cell type. Int J Cancer 1999 0.83
66 Thyroid hormone receptors repress estrogen receptor activation of a TRE. Mol Endocrinol 1991 0.83
67 Tight-binding repressors of the lac operon: selection system and in vitro analysis. J Bacteriol 1979 0.82
68 Thyroid hormone receptor homodimers can function as ligand-sensitive repressors. Mol Endocrinol 1995 0.81
69 Similar ligand-induced conformational changes of thyroid hormone receptors regulate homo- and heterodimeric functions. J Biol Chem 1995 0.80
70 Differential effects of all-trans and 13-cis-retinoic acid on mRNA levels of nuclear retinoic acid receptors in rat lung and liver. Biochem Biophys Res Commun 1991 0.80
71 Potential role for retinoic acid receptor-gamma in the inhibition of breast cancer cells by selective retinoids and interferons. Cancer Res 1996 0.80
72 Escape synthesis of beta-galactosidase in strains of Escherichia coli lysogenic for lambda cI-857-h-80-t-68-dlac. Mol Gen Genet 1969 0.79
73 ET-1 expression and growth inhibition of prostate cancer cells: a retinoid target with novel specificity. Cancer Res 1998 0.78
74 A novel class of retinoid antagonists and their mechanism of action. J Biol Chem 1996 0.78
75 Recombinant human retinoic acid receptor beta. Binding of synthetic retinoids and transcriptional activation. J Biol Chem 1994 0.78
76 Coordinate expression of functionally distinct thyroid hormone receptor alpha isoforms during neonatal brain development. Mol Endocrinol 1991 0.78
77 Glucocorticoid hormone interactions with cloned proviral DNA of mouse mammary tumor virus. J Steroid Biochem 1984 0.77
78 Regulation of H1(0) gene expression by nuclear receptors through an unusual response element: implications for regulation of cell proliferation. DNA Cell Biol 1995 0.77
79 Variable responsiveness of hormone-inducible hybrid genes in different cell lines. Mol Endocrinol 1988 0.77
80 A mutant lactose repressor with altered inducer and operator binding parameters. J Mol Biol 1985 0.77
81 Mapping of I Gene mutations which lead to repressors with increased affinity for lac operator. J Mol Biol 1981 0.77
82 Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function. Mol Endocrinol 1995 0.76
83 Retinoid actions and implications for prevention and therapy of oral cancer. Int J Oral Maxillofac Surg 1996 0.76
84 Treatment of cervical intraepithelial neoplasia levels 2 and 3 with adapalene, a retinoid-related molecule. J Low Genit Tract Dis 2001 0.76
85 Molecular mechanisms of action for vitamin A-derived hormones. Prog Clin Biol Res 1994 0.75
86 Selective activation of an apoptotic retinoid precursor in macrophage cell lines. J Biol Chem 1998 0.75
87 [Genetic analysis of inductor and operator binding sites of the lactose repressor]. Hoppe Seylers Z Physiol Chem 1972 0.75