Published in Biochemistry on April 09, 1996
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily. Expert Opin Drug Metab Toxicol (2008) 3.37
Maternal aldehyde elimination during pregnancy preserves the fetal genome. Mol Cell (2014) 2.24
Effects of oxidative alcohol metabolism on the mitochondrial permeability transition pore and necrosis in a mouse model of alcoholic pancreatitis. Gastroenterology (2012) 1.67
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin. J Clin Invest (2006) 1.53
Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. Physiol Rev (2014) 1.51
Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2. Chem Biol Interact (2012) 1.45
Mitochondrial aldehyde dehydrogenase and cardiac diseases. Cardiovasc Res (2010) 1.39
Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress. Free Radic Biol Med (2012) 1.26
Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos (2010) 1.24
Evaluation of aldehyde dehydrogenase 1 promoter polymorphisms identified in human populations. Alcohol Clin Exp Res (2003) 1.15
Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues. Arch Biochem Biophys (2007) 1.14
Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases. J Biol Chem (2008) 1.13
Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A (1997) 1.13
Genes encoding enzymes involved in ethanol metabolism. Alcohol Res (2012) 1.09
Aldehyde dehydrogenase-2 transgene ameliorates chronic alcohol ingestion-induced apoptosis in cerebral cortex. Toxicol Lett (2009) 1.05
Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid-dependent axial patterning in metazoans. Proc Natl Acad Sci U S A (2010) 1.04
Inactivation of cytosolic aldehyde dehydrogenase via S-nitrosylation in ethanol-exposed rat liver. FEBS Lett (2007) 1.03
Pathogenesis of alcoholic liver disease: the role of nuclear receptors. Exp Biol Med (Maywood) (2010) 1.00
Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term. J Perinat Med (2010) 1.00
Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry. J Biol Chem (2012) 0.98
Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin. J Biol Chem (2008) 0.98
Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision. Prog Retin Eye Res (2012) 0.93
Nitroglycerin use in myocardial infarction patients. Circ J (2011) 0.93
Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications. J Proteomics (2011) 0.91
Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1. J Biol Chem (2009) 0.91
Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2. J Biol Chem (2009) 0.88
Drug interaction between ethanol and 3,4-methylenedioxymethamphetamine ("ecstasy"). Toxicol Lett (2009) 0.85
Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease. Oxid Med Cell Longev (2013) 0.81
Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol. J Exp Med (2001) 0.80
Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors. J Med Chem (2015) 0.80
Studies of the esterase activity of cytosolic aldehyde dehydrogenase with resorufin acetate as substrate. Biochem J (1997) 0.79
Estrogen receptor ERα plays a major role in ethanol-evoked myocardial oxidative stress and dysfunction in conscious female rats. Alcohol (2015) 0.78
Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human Diseases. Biomed Res Int (2015) 0.78
Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary. Reprod Toxicol (2012) 0.77
Ameliorating effects of Mango (Mangifera indica L.) fruit on plasma ethanol level in a mouse model assessed with H-NMR based metabolic profiling. J Clin Biochem Nutr (2011) 0.77
Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases. Curr Mol Pharmacol (2015) 0.77
De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility. Endocrinology (2016) 0.76
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid. Sci Rep (2016) 0.75
Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat. Mol Ther Nucleic Acids (2016) 0.75
ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective. J Biomed Sci (2017) 0.75
Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway. Sci Rep (2016) 0.75
Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors. Chem Biol Interact (2015) 0.75
Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium. Sci Rep (2015) 0.75
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing. Anal Biochem (1985) 1.49
Purification and characterization of three distinct glutathione transferases from mouse liver. Biochemistry (1986) 1.32
Inhibitors for distinction of three types of human glutathione transferase. FEBS Lett (1985) 1.26
Isoenzymes of glutathione transferase in rat kidney cytosol. Biochem J (1985) 1.13
Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells. Cancer Res (1989) 1.12
Simple inhibition studies for distinction between homodimeric and heterodimeric isoenzymes of glutathione transferase. J Biol Chem (1986) 1.09
Expression of class Pi glutathione transferase in human malignant melanoma cells. Carcinogenesis (1987) 1.05
The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin. J Med Chem (2000) 1.03
Daidzin decreases ethanol consumption in rats. Alcohol Clin Exp Res (1996) 1.02
Synthesis of potential antidipsotropic isoflavones: inhibitors of the mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway. J Med Chem (2001) 0.95
Evidence that epidermal growth factor is present in swiftlet's (Collocalia) nest. Comp Biochem Physiol B (1987) 0.91
Differences in the occurrence of glutathione transferase isoenzymes in rat lung and liver. Biochem Biophys Res Commun (1985) 0.91
Linkage groups and recombination in the malaria mosquito. J Hered (1973) 0.89
Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1. 145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): characterization and its inhibition by isoflavones. J Steroid Biochem Mol Biol (1999) 0.86
Basic features of class-I alcohol dehydrogenase: variable and constant segments coordinated by inter-class and intra-class variability. Conclusions from characterization of the alligator enzyme. Eur J Biochem (1993) 0.85
Metallothionein-III antagonizes the neurotoxic and neurotrophic effects of amyloid beta peptides. Biochem Biophys Res Commun (2001) 0.82
Structure and function of ovotransferrin. II. Iron-transferring activity of iron-binding fragments of ovotransferrin with chicken embryo red cells. J Biol Chem (1982) 0.81
Studies on shrew (Suncus murinus) epidermal growth factor. Acta Endocrinol (Copenh) (1986) 0.81
Glutathione transferases of classes alpha, mu and pi show selective expression in different regions of rat kidney. Xenobiotica (1993) 0.81
Daidzein sulfoconjugates are potent inhibitors of sterol sulfatase (EC 3.1.6.2). Biochem Biophys Res Commun (1997) 0.81
Esterase activity of rabbit pulmonary angiotensin converting enzyme. Biochem Biophys Res Commun (1980) 0.79
Subunit composition of the zinc proteins alpha- and beta-lipovitellin from chicken. J Protein Chem (2000) 0.79
Liver alcohol and aldehyde dehydrogenase isozymes in a Chinese population in Hong Kong. Hum Hered (1989) 0.78
The effect of pH on the kinetics of iron release from diferric ovotransferrin induced by pyrophosphate. J Inorg Biochem (1987) 0.78
Structure and function of ovotransferrin. I. Production of iron-binding fragments from iron-ovotransferrin by the action of immobilized subtilisin. Purification and characterization of the fragments. J Biol Chem (1982) 0.78
Isozyme developments in mammalian class-I alcohol dehydrogenase. cDNA cloning, functional correlations, and lack of evidence for genetic isozymes in rabbit. Eur J Biochem (1993) 0.77
The cytolytic effect of cobra cardiotoxin on Ehrlich ascites tumor cells and its inhibition by Ca2+. Naunyn Schmiedebergs Arch Pharmacol (1976) 0.77
Glutathione transferase catalyzed conjugation of benzo[a]pyrene 7,8-diol 9,10-epoxide with glutathione in human skin. Chem Biol Interact (1989) 0.77
Steroidogenesis in Varanus adrenals in vitro. Comp Biochem Physiol B (1975) 0.75
Identification of human alcohol dehydrogenase isozymes by disc polyacrylamide gel electrophoresis in 7 M urea. Anal Biochem (1985) 0.75
Amylase isozymes in the mosquito, Culex tritaeniorhynchus. Can J Genet Cytol (1976) 0.75
Studies on the status of disulfide linkages and tyrosine residues in cardiotoxin. Biochem Biophys Res Commun (1975) 0.75
Beta 2 (Oriental) human liver alcohol dehydrogenases do not exhibit subunit interaction: oxidation of cyclohexanol by homo- and heterodimers. Biochemistry (1987) 0.75
Metal binding to angiotensin converting enzyme: implications for the metal binding site. J Inorg Biochem (1986) 0.75
The chemistry and biological effects of cardiotoxin from the Chinese cobra (N. naja Linn.) on hormonal responses in isolated cell systems. Toxicon (1975) 0.75
Class 2 aldehyde dehydrogenase. Characterization of the hamster enzyme, sensitive to daidzin and conserved within the family of multiple forms. FEBS Lett (1997) 0.75
Examination of subunit interaction in human ADH: carboxymethylation of the heterodimer beta 2 gamma 1. Biochem Int (1991) 0.75
Kinetics of pyrophosphate induced iron release from diferric ovotransferrin. J Inorg Biochem (1987) 0.75
Substrate specificity of human class I alcohol dehydrogenase homo- and heterodimers containing the beta 2 (Oriental) subunit. Biochemistry (1987) 0.75