Published in Proc Natl Acad Sci U S A on April 02, 1996
Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol Cell Biol (1997) 3.02
NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. J Cell Biol (1998) 2.49
Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation. Mol Cell Biol (2002) 1.08
Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome. Diabetes (2010) 1.07
Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis. J Pharmacol Exp Ther (2009) 0.98
Effect of indomethacin on capillary growth and microvasculature in chronically stimulated rat skeletal muscles. J Physiol (2000) 0.83
Constitutive and Inducible Expression of Invasion-related Factors in PC-3 Prostate Cancer Cells. J Cancer Prev (2015) 0.75
Repairing the Brain by SCF+G-CSF Treatment at 6 Months Postexperimental Stroke: Mechanistic Determination of the Causal Link Between Neurovascular Regeneration and Motor Functional Recovery. ASN Neuro (2016) 0.75
Tumor angiogenesis. Adv Cancer Res (1985) 5.66
Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells. J Exp Med (1992) 5.32
Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radic Res Commun (1992) 4.45
Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev (1992) 3.47
Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative. Mol Cell Biol (1992) 2.67
NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation. J Exp Med (1994) 2.10
Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes. J Immunol (1993) 1.84
Mechanisms of angiogenesis. Annu Rev Physiol (1987) 1.68
Fibroblast growth factor: structural and biological properties. J Cell Physiol Suppl (1987) 1.52
Pyrrolidine dithiocarbamate inhibits induction of nitric oxide synthase activity in rat alveolar macrophages. Biochem Biophys Res Commun (1993) 1.29
Upregulation of urokinase receptor expression on migrating endothelial cells. J Cell Biol (1993) 1.18
Endothelial cell gene expression in response to injury. FASEB J (1993) 1.13
Recent insights into coronary collateral circulation. Circulation (1992) 1.00
Inhibition of NF-kappa B activation by vitamin E derivatives. Biochem Biophys Res Commun (1993) 0.97
Protection by diethyldithiocarbamate against carbon tetrachloride lethality in rats and against carbon tetrachloride-induced lipid peroxidation in vitro. Biochem Pharmacol (1973) 0.96
12(R)-hydroxyeicosatrienoic acid, a potent chemotactic and angiogenic factor produced by the cornea. Exp Eye Res (1991) 0.88
A closed eye contact lens model of corneal inflammation. Part 1: Increased synthesis of cytochrome P450 arachidonic acid metabolites. Invest Ophthalmol Vis Sci (1995) 0.87
Angiogenesis factor from human myocardial infarcts. Lancet (1983) 0.87
Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes. Biochim Biophys Acta (1994) 0.87
12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium. J Biol Chem (1988) 0.86
Direct stimulation of limbal microvessel endothelial cell proliferation and capillary formation in vitro by a corneal-derived eicosanoid. Am J Pathol (1996) 0.85
Diethyldithiocarbamate provides partial protection against pulmonary and lymphoid oxygen toxicity. J Pharmacol Exp Ther (1986) 0.84
Activation of nuclear factor kappa B and oncogene expression by 12(R)-hydroxyeicosatrienoic acid, an angiogenic factor in microvessel endothelial cells. J Biol Chem (1994) 0.83
Dual metabolic pathways of 12-HETE in rat aortic smooth muscle cells. Prostaglandins (1992) 0.81
Ocular effects of a novel cytochrome P-450-dependent arachidonic acid metabolite. Invest Ophthalmol Vis Sci (1989) 0.81
Metabolism of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid and other hydroxylated fatty acids by the reductase pathway in porcine polymorphonuclear leukocytes. Biochemistry (1990) 0.81
Acquired coronary angiogenesis after myocardial infarction. Cardiology (1993) 0.78
NADPH-dependent formation of 15- and 12-hydroxyeicosatrienoic acid from arachidonic acid by rat epidermal microsomes. Eicosanoids (1991) 0.78
Isolated coronary-perfused mammalian heart: assessment of eicosanoid and platelet-activating factor release and effects. Methods Enzymol (1990) 0.77
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A (2001) 2.21
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood (2001) 1.88
Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci U S A (1994) 1.85
Heme oxygenase-1 protects against radiocontrast-induced acute kidney injury by regulating anti-apoptotic proteins. Kidney Int (2007) 1.80
Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c. Diabetologia (2005) 1.69
Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. Science (1989) 1.67
Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats. Hypertension (2001) 1.48
Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway. J Pharmacol Exp Ther (1987) 1.40
Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis. J Cell Biochem (1998) 1.35
Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells. Proc Soc Exp Biol Med (1997) 1.24
Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors. J Clin Invest (2001) 1.21
Promotive effects of a silk film on epidermal recovery from full-thickness skin wounds. Proc Soc Exp Biol Med (2000) 1.20
A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats. Hypertension (1995) 1.19
Heme metabolism and in vitro erythropoiesis in anemia associated with hypochromic microcytosis. Am J Hematol (1988) 1.19
Erythroid 5-aminolevulinate synthase is located on the X chromosome. Am J Hum Genet (1990) 1.17
Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment. Blood (1993) 1.13
Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats. J Clin Invest (1990) 1.11
12(R)-hydroxyicosatetraenoic acid: a cytochrome-P450-dependent arachidonate metabolite that inhibits Na+,K+-ATPase in the cornea. Proc Natl Acad Sci U S A (1987) 1.11
Presence of cytochrome P-450-dependent monooxygenase in intimal cells of the hog aorta. Hypertension (1986) 1.09
Impact of silencing HO-2 on EC-SOD and the mitochondrial signaling pathway. J Cell Biochem (2007) 1.08
Renal cytochrome P-450-arachidonic acid metabolism: localization and hormonal regulation in SHR. Am J Physiol (1992) 1.08
Overexpression of the heme oxygenase gene in renal cell carcinoma. Proc Soc Exp Biol Med (1997) 1.07
CYP4A1 antisense oligonucleotide reduces mesenteric vascular reactivity and blood pressure in SHR. Am J Physiol Regul Integr Comp Physiol (2001) 1.07
Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression. J Pharmacol Exp Ther (1999) 1.07
Modulation by 20-HETE of phenylephrine-induced mesenteric artery contraction in spontaneously hypertensive and Wistar-Kyoto rats. Hypertension (2001) 1.06
Heme oxygenase isoform-specific expression and distribution in the rat kidney. Kidney Int (2001) 1.05
Presence of heme oxygenase and NADPH cytochrome P-450 (c) reductase in human corneal epithelium. Invest Ophthalmol Vis Sci (1987) 1.04
Cytochrome P450 4A expression and arachidonic acid omega-hydroxylation in the kidney of the spontaneously hypertensive rat. Nephron (1996) 1.03
Heme oxygenase induction with attenuation of experimentally induced corneal inflammation. Biochem Pharmacol (1997) 1.02
Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow. Proc Natl Acad Sci U S A (1997) 1.02
Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid. J Pharmacol Exp Ther (1986) 1.01
Carbon monoxide produced by isolated arterioles attenuates pressure-induced vasoconstriction. Am J Physiol Heart Circ Physiol (2001) 0.99
Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in inflammation and growth. Cell Mol Biol (Noisy-le-grand) (2005) 0.98
Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney. Biochem J (1986) 0.96
Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant-induced injury. Am J Physiol (1999) 0.95
Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine. Proc Natl Acad Sci U S A (1991) 0.95
Cytochrome P450-dependent arachidonic acid metabolism in human kidney. Kidney Int (1990) 0.95
Contribution of cytochrome P-450 4A1 and 4A2 to vascular 20-hydroxyeicosatetraenoic acid synthesis in rat kidneys. Am J Physiol (1999) 0.95
Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements. Biochem Biophys Res Commun (1996) 0.94
Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem (2000) 0.94
A closed eye contact lens model of corneal inflammation. Part 2: Inhibition of cytochrome P450 arachidonic acid metabolism alleviates inflammatory sequelae. Invest Ophthalmol Vis Sci (1995) 0.94
19(S)-hydroxyeicosatetraenoic acid is a potent stimulator of renal Na+-K+-ATPase. Biochem Biophys Res Commun (1988) 0.92
Heme oxygenase-1 gene expression increases vascular relaxation and decreases inducible nitric oxide synthase in diabetic rats. Cell Mol Biol (Noisy-le-grand) (2005) 0.92
Hemin and L-arginine regulation of blood pressure in spontaneous hypertensive rats. J Am Soc Nephrol (1991) 0.92
Chronic treatment with tin normalizes blood pressure in spontaneously hypertensive rats. Hypertension (1991) 0.90
Vasoregulatory function of the heme-heme oxygenase-carbon monoxide system. Am J Hypertens (2001) 0.90
Mechanisms of differentiation of U937 leukemic cells induced by GM-CSF and 1,25(OH)2 vitamin D3. Leuk Res (1991) 0.90
Hemin stimulation of hemopoiesis in murine long-term bone marrow culture. Exp Hematol (1991) 0.90
Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance. J Neurosci Res (2002) 0.89
Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs. Proc Assoc Am Physicians (1996) 0.89
Sensitivity of human tissue heme oxygenase to a new synthetic metalloporphyrin. Hepatology (1989) 0.89
Tin-mediated heme oxygenase gene activation and cytochrome P450 arachidonate hydroxylase inhibition in spontaneously hypertensive rats. Am J Med Sci (1994) 0.89
Heme-induced cell adhesion in the pathogenesis of sickle-cell disease and inflammation. Trends Pharmacol Sci (2001) 0.88
12(R)-hydroxyeicosatrienoic acid, a potent chemotactic and angiogenic factor produced by the cornea. Exp Eye Res (1991) 0.88
Regulation of heme oxygenase gene expression by cobalt in rat liver and kidney. Eur J Biochem (1990) 0.87
Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes. Biochim Biophys Acta (1994) 0.87
Induction of heme oxygenase-1 in renovascular hypertension is associated with inhibition of apoptosis. Cell Mol Biol (Noisy-le-grand) (2007) 0.87
A closed eye contact lens model of corneal inflammation. Part 1: Increased synthesis of cytochrome P450 arachidonic acid metabolites. Invest Ophthalmol Vis Sci (1995) 0.87
Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone. Proc Soc Exp Biol Med (1999) 0.87
Identification of heme oxygenase and cytochrome P-450 in the rabbit heart. J Mol Cell Cardiol (1987) 0.87
Dual role of heme oxygenase in epithelial cell injury: contrasting effects of short-term and long-term exposure to oxidant stress. J Lab Clin Med (1996) 0.86
Heme oxygenase-1 expression levels are cell cycle dependent. Biochem Biophys Res Commun (2003) 0.86
Properties of human kidney heme oxygenase: inhibition by synthetic heme analogues and metalloporphyrins. Biochem Biophys Res Commun (1988) 0.86
Age-related changes in renal cytochrome P-450 arachidonic acid metabolism in spontaneously hypertensive rats. Am J Physiol (1992) 0.86
12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium. J Biol Chem (1988) 0.86
Upregulation of human heme oxygenase gene expression by Ets-family proteins. J Cell Biochem (1999) 0.86
Purification and characterization of cytochrome P-450-dependent arachidonic acid epoxygenase from human liver. J Biol Chem (1988) 0.86
Direct stimulation of limbal microvessel endothelial cell proliferation and capillary formation in vitro by a corneal-derived eicosanoid. Am J Pathol (1996) 0.85
Differential induction of heme oxygenase in the hepatocarcinoma cell line (Hep3B) by environmental agents. J Cell Biochem (1992) 0.85
Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients. Am J Hematol (1993) 0.84
Cytochrome P450 dependent metabolism of arachidonic acid in bovine corneal epithelium. Biochem Biophys Res Commun (1985) 0.84
Renal cytochrome P-450-dependent metabolism of arachidonic acid in spontaneously hypertensive rats. Biochem Pharmacol (1988) 0.84
Novel regulatory sites of the human heme oxygenase-1 promoter region. Biochem Biophys Res Commun (1993) 0.84
Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice. J Cell Biochem (2011) 0.84
Activation of nuclear factor kappa B and oncogene expression by 12(R)-hydroxyeicosatrienoic acid, an angiogenic factor in microvessel endothelial cells. J Biol Chem (1994) 0.83
Cytochrome P450-dependent arachidonate metabolism in corneal epithelium: formation of biologically active compounds. Adv Prostaglandin Thromboxane Leukot Res (1987) 0.83
Swelling in the isolated perfused cornea induced by 12(R)hydroxyeicosatetraenoic acid. Invest Ophthalmol Vis Sci (1993) 0.83
Regulation of cyclooxygenase-2 by hypoxia and peroxisome proliferators in the corneal epithelium. J Biol Chem (2000) 0.82
Modulation of corneal heme oxygenase expression by oxidative stress agents. J Ocul Pharmacol Ther (1995) 0.82
Comparative effects of heme and metalloporphyrins on interferon-gamma-mediated pathways in monocytic cells (THP-1). Proc Soc Exp Biol Med (1993) 0.82
Heme metabolism and erythropoiesis in abnormal iron states: role of delta-aminolevulinic acid synthase and heme oxygenase. Exp Hematol (1985) 0.82
Effect of age on rat liver heme and drug metabolism. Exp Gerontol (1985) 0.82
The fetal phonogram: a measure of fetal activity. Lancet (1986) 0.81
Ocular effects of a novel cytochrome P-450-dependent arachidonic acid metabolite. Invest Ophthalmol Vis Sci (1989) 0.81
ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice. Nutr Diabetes (2012) 0.81
Benzene modulation of liver cell structure and heme-cytochrome P-450 metabolism. Am J Med Sci (1986) 0.81
TNF-alpha-mediated cell death is attenuated by retrovirus delivery of human heme oxygenase-1 gene into human microvessel endothelial cells. Transplant Proc (2002) 0.81
Kinetic properties of the membrane-bound human liver mitochondrial protoporphyrinogen oxidase. Arch Biochem Biophys (1985) 0.81
Quantitation of human erythroid-specific porphobilinogen deaminase mRNA by the polymerase chain reaction. Exp Hematol (1991) 0.81
The renal cytochrome P-450 arachidonic acid system. Pediatr Nephrol (1992) 0.81
The hematopoietic stromal microenvironment promotes retrovirus-mediated gene transfer into hematopoietic stem cells. Stem Cells (1993) 0.80
Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs. Proc Natl Acad Sci U S A (2001) 0.80
Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity. J Pharmacol Exp Ther (2000) 0.80
Immunochemical studies on the contribution of NADPH cytochrome P-450 reductase to the cytochrome P-450-dependent metabolism of arachidonic acid. Arch Biochem Biophys (1987) 0.80
Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats. J Hypertens (1989) 0.80
Diminished heme oxygenase-1 mRNA expression in RPE cells from diabetic donors as quantitated by competitive RT/PCR. Curr Eye Res (1997) 0.80