Published in Pharmacopsychiatry on October 01, 1995
Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci U S A (1999) 3.82
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet (2006) 2.17
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. Proc Natl Acad Sci U S A (2001) 1.37
Brain serotonin receptors and transporters: initiation vs. termination of escalated aggression. Psychopharmacology (Berl) (2010) 1.03
c-Fos identification of neuroanatomical sites associated with haloperidol and clozapine disruption of maternal behavior in the rat. Neuroscience (2010) 1.01
The serotonin system in autism spectrum disorder: From biomarker to animal models. Neuroscience (2015) 0.99
(+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners. Bioorg Med Chem Lett (2009) 0.97
Anti-aggressive effects of agonists at 5-HT1B receptors in the dorsal raphe nucleus of mice. Psychopharmacology (Berl) (2007) 0.96
The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors. Pharmacol Biochem Behav (2009) 0.95
Increased dopaminergic and 5-hydroxytryptaminergic activities in male rat brain following long-term treatment with anabolic androgenic steroids. Br J Pharmacol (1999) 0.94
Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors. Neuropsychopharmacology (2014) 0.93
The serotonergic central nervous system of the Drosophila larva: anatomy and behavioral function. PLoS One (2012) 0.93
Gestational treatment with cocaine and fluoxetine alters oxytocin receptor number and binding affinity in lactating rat dams. Int J Dev Neurosci (2004) 0.91
Drugs, biogenic amine targets and the developing brain. Dev Neurosci (2009) 0.90
Behavioral and pharmacogenetics of aggressive behavior. Curr Top Behav Neurosci (2012) 0.90
Individual vulnerability to escalated aggressive behavior by a low dose of alcohol: decreased serotonin receptor mRNA in the prefrontal cortex of male mice. Genes Brain Behav (2009) 0.89
The role of the serotonergic system at the interface of aggression and suicide. Neuroscience (2013) 0.89
Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150. Eur J Nucl Med Mol Imaging (2003) 0.89
Antiaggressive activity of central oxytocin in male rats. Psychopharmacology (Berl) (2013) 0.87
The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. Pharmacol Biochem Behav (2005) 0.87
Increased accumbal dopamine during daily alcohol consumption and subsequent aggressive behavior in rats. Psychopharmacology (Berl) (2006) 0.86
5-HT(1B) receptor inhibition of alcohol-heightened aggression in mice: comparison to drinking and running. Psychopharmacology (Berl) (2007) 0.86
Y1 receptors regulate aggressive behavior by modulating serotonin pathways. Proc Natl Acad Sci U S A (2004) 0.86
Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams. Pharmacol Biochem Behav (2003) 0.85
Social instigation and aggression in postpartum female rats: role of 5-Ht1A and 5-Ht1B receptors in the dorsal raphé nucleus and prefrontal cortex. Psychopharmacology (Berl) (2010) 0.83
Evaluation of the serotonergic genes htr1A, htr1B, htr2A, and slc6A4 in aggressive behavior of golden retriever dogs. Behav Genet (2007) 0.81
Dynamic interactions of behavior and amine neurochemistry in acquisition and maintenance of social rank in crayfish. Brain Behav Evol (2001) 0.81
Long-term citalopram maintenance in mice: selective reduction of alcohol-heightened aggression. Psychopharmacology (Berl) (2007) 0.80
The C1473G polymorphism in the tryptophan hydroxylase-2 gene and intermale aggression in mice. Dokl Biol Sci (2005) 0.78
Measuring virgin female aggression in the female intruder test (FIT): effects of oxytocin, estrous cycle, and anxiety. PLoS One (2014) 0.78
Combined norepinephrine/serotonergic reuptake inhibition: effects on maternal behavior, aggression, and oxytocin in the rat. Front Psychiatry (2011) 0.78
Biochemical, behavioral, physiologic, and neurodevelopmental changes in mice deficient in monoamine oxidase A or B. Brain Res Bull (2001) 0.78
Serotonin receptors in depression: from A to B. F1000Res (2017) 0.77
Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes. Front Neurosci (2014) 0.77
Aggression-reducing effects of F15599, a novel selective 5-HT1A receptor agonist, after microinjection into the ventral orbital prefrontal cortex, but not in infralimbic cortex in male mice. Psychopharmacology (Berl) (2013) 0.77
Aminergic control of social status in crayfish agonistic encounters. PLoS One (2013) 0.76
Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice. Transl Psychiatry (2016) 0.76
Independent effects of early-life experience and trait aggression on cardiovascular function. Am J Physiol Regul Integr Comp Physiol (2016) 0.76
Pain behavior changes following disc puncture relate to nucleus pulposus rather than to the disc injury per se: an experimental study in rats. Open Orthop J (2011) 0.75
The case for basic research on the psychopharmacology of aggression. J Clin Psychopharmacol (2012) 0.75
Antipsychotic drugs on maternal behavior in rats. Behav Pharmacol (2015) 0.75
Editorial: Reproductive Neuroendocrinology and Social Behavior. Front Neurosci (2016) 0.75
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature (1985) 7.14
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell (2000) 6.45
Organization and sequence studies of the 17-piece chicken conalbumin gene. Nature (1979) 4.36
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proc Natl Acad Sci U S A (1982) 4.30
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J (2001) 3.22
An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite. Nucleic Acids Res (1983) 3.11
Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products. Science (1985) 2.81
Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci U S A (1998) 2.54
Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proc Natl Acad Sci U S A (2001) 2.46
Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (1994) 2.32
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
Antidepressants recruit new neurons to improve stress response regulation. Mol Psychiatry (2011) 2.11
A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products. Nature (1986) 1.93
Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature (1998) 1.88
Cloning and characterization of a Drosophila tyramine receptor. EMBO J (1990) 1.42
Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit. Nucleic Acids Res (1983) 1.40
The immunoglobulin heavy chain enhancer is stimulated by the adenovirus type 2 E1A products in mouse fibroblasts. Proc Natl Acad Sci U S A (1986) 1.39
Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology (Berl) (2001) 1.38
5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze. J Neurosci (1999) 1.35
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. J Neurosci (2001) 1.34
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol (1993) 1.34
Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. J Neurosci (2001) 1.33
Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proc Natl Acad Sci U S A (1992) 1.32
Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc Natl Acad Sci U S A (2001) 1.30
Complications associated with genetic background effects in research using knockout mice. Psychopharmacology (Berl) (1999) 1.28
A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. EMBO J (1992) 1.28
Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis. J Pharmacol Exp Ther (2007) 1.27
The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals. Neuroscience (1994) 1.24
Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Nat Genet (1996) 1.24
Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase. Proc Natl Acad Sci U S A (1990) 1.22
Potential panic disorder syndrome: clinical and genetic linkage evidence. Am J Med Genet (2000) 1.20
Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behav Neurosci (1999) 1.20
Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron (1999) 1.18
Altered fear circuits in 5-HT(1A) receptor KO mice. Biol Psychiatry (2000) 1.17
Discriminant analysis of the localization of aggression-inducing electrode placements in the hypothalamus of male rats. Brain Res (1983) 1.17
G(olf)alpha mediates dopamine D1 receptor signaling. J Neurosci (2000) 1.12
Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology (1999) 1.11
The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Curr Opin Neurobiol (2000) 1.10
Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice. J Pharmacol Exp Ther (2001) 1.10
Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. Proc Natl Acad Sci U S A (1993) 1.10
Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology (2008) 1.09
Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. J Neurosci (1998) 1.09
Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice. Ann N Y Acad Sci (1997) 1.08
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol (1993) 1.08
NKD, a developmentally regulated tachykinin receptor in Drosophila. J Biol Chem (1992) 1.08
Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Mol Psychiatry (2007) 1.05
Serotonin, serotonergic receptors, selective serotonin reuptake inhibitors and sexual behaviour. Int Clin Psychopharmacol (1998) 1.04
Serotonin receptors. Genetic insights into serotonin function. Curr Biol (1995) 1.03
Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. J Biol Chem (1992) 1.03
Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice. J Neurosci (1999) 1.02
BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Transl Psychiatry (2013) 1.02
Characterization of stress-induced long-term behavioural changes in rats: evidence in favor of anxiety. Physiol Behav (1992) 0.99
5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochem Int (1994) 0.99
Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology (Berl) (1997) 0.98
Inescapable footshocks induce progressive and long-lasting behavioural changes in male rats. Physiol Behav (1992) 0.97
Short inescapable stress produces long-lasting changes in the brain-pituitary-adrenal axis of adult male rats. Neuroendocrinology (1993) 0.97
Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies. J Neurochem (1997) 0.96
Comparison of aggressive behaviour induced by electrical stimulation in the hypothalamus of male and female rats. Prog Brain Res (1984) 0.95
The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family. EMBO J (1992) 0.94
5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. J Neurochem (2001) 0.94
Rodent models of aggressive behavior and serotonergic drugs. Prog Neuropsychopharmacol Biol Psychiatry (1992) 0.93
Risk of facial splashes in four major surgical specialties in a multicentre study. J Hosp Infect (2007) 0.93
Intravenous cocaine self-administration in mice lacking 5-HT1B receptors. Pharmacol Biochem Behav (1997) 0.92
Differential expression of the mouse D2 dopamine receptor isoforms. FEBS Lett (1991) 0.92
Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice. Biol Psychiatry (2001) 0.92
Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. J Pharmacol Exp Ther (2001) 0.92
Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT(1A) or 5-HT(1B) receptor knockout mice. J Neurochem (2000) 0.92
Anxiolytic-like actions of toluene in the burying behavior and plus-maze tests: differences in sensitivity between 5-HT(1B) knockout and wild-type mice. Behav Brain Res (2000) 0.91
Chronic treatment with eltoprazine does not lead to tolerance in its anti-aggressive action, in contrast to haloperidol. Eur Neuropsychopharmacol (1996) 0.91
Molecular heterogeneity along the dorsal-ventral axis of the murine hippocampal CA1 field: a microarray analysis of gene expression. Neuroscience (2005) 0.91
Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology (2000) 0.91
Adult partner preference and sexual behavior of male rats affected by perinatal endocrine manipulations. Horm Behav (1991) 0.90
Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. Eur J Pharmacol (2001) 0.90
Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. J Neurochem (2001) 0.90
Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. J Neurosci (1995) 0.90
Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons. J Cell Sci (1999) 0.90
Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue. Neuropsychopharmacology (1999) 0.90
Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas. Oncogene (2011) 0.90
5-HT1B receptor knock out--behavioral consequences. Behav Brain Res (1996) 0.89
5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935. Mol Pharmacol (1997) 0.88
Adult hippocampal neurogenesis: an actor in the antidepressant-like action. Ann Pharm Fr (2013) 0.88
Modulation of the effects of cocaine by 5-HT1B receptors: a comparison of knockouts and antagonists. Pharmacol Biochem Behav (2000) 0.88
Male and female 5-HT(1B) receptor knockout mice have higher body weights than wildtypes. Physiol Behav (2002) 0.88
Novel strategies to probe the functions of serotonin receptors. Biol Psychiatry (1998) 0.88
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders. Ann N Y Acad Sci (1999) 0.87
Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse. J Pharmacol Exp Ther (2001) 0.87
Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. J Neurochem (2003) 0.87
Postsynaptic 5-HT1 receptors and offensive aggression in rats: a combined behavioural and autoradiographic study with eltoprazine. Pharmacol Biochem Behav (1991) 0.86
Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans. Mol Psychiatry (2012) 0.86
Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology (Berl) (1999) 0.86
Lack of 5-HT(1B) receptor and of serotonin transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus. Neuroscience (2002) 0.86
Serotonergic modulation of social interactions in isolated male mice. Psychopharmacology (Berl) (1989) 0.86
New players in the 5-HT receptor field: genes and knockouts. Trends Pharmacol Sci (1995) 0.86
In vitro induction of apoptosis or differentiation by dopamine in an immortalized olfactory neuronal cell line. J Neurochem (1997) 0.85
Stress and hypothermia in mice in a nose-only cigarette smoke exposure system. Inhal Toxicol (2006) 0.85
Combining genetic and genomic approaches to study mood disorders. Eur Neuropsychopharmacol (2001) 0.85
Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice. Neuroreport (1995) 0.84
Region-specific enhancement of basal extracellular and cocaine-evoked dopamine levels following constitutive deletion of the Serotonin(1B) receptor. J Neurochem (2000) 0.84
5-hydroxytryptamine-moduline, a new endogenous cerebral peptide, controls the serotonergic activity via its specific interaction with 5-hydroxytryptamine1B/1D receptors. Mol Pharmacol (1996) 0.84