Published in Proc Natl Acad Sci U S A on August 16, 2004
The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl) (2007) 1.14
Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol (2009) 1.14
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Brain serotonin receptors and transporters: initiation vs. termination of escalated aggression. Psychopharmacology (Berl) (2010) 1.03
Neuromolecular responses to social challenge: common mechanisms across mouse, stickleback fish, and honey bee. Proc Natl Acad Sci U S A (2014) 1.02
Mouse behavioural analysis in systems biology. Biochem J (2005) 0.99
Unravelling the neurophysiological basis of aggression in a fish model. BMC Genomics (2010) 0.96
Ominous odors: olfactory control of instinctive fear and aggression in mice. Curr Opin Neurobiol (2013) 0.93
Neuropeptide Y and posttraumatic stress disorder. Mol Psychiatry (2012) 0.93
Peptidergic influences on proliferation, migration, and placement of neural progenitors in the adult mouse forebrain. Proc Natl Acad Sci U S A (2008) 0.90
Behavioral and pharmacogenetics of aggressive behavior. Curr Top Behav Neurosci (2012) 0.90
Delayed stress-induced differences in locomotor and depression-related behaviour in female neuropeptide-Y Y1 receptor knockout mice. J Psychopharmacol (2009) 0.81
Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell (1996) 10.40
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J Neurosci (1999) 4.56
Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res (1999) 3.27
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev (1999) 3.07
A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice. Horm Behav (1997) 2.47
Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers. Regul Pept (1984) 2.27
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II. Science (1994) 2.20
The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol Behav (2002) 1.89
Behavioral phenotyping of mice in pharmacological and toxicological research. Exp Toxicol Pathol (2003) 1.85
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nat Med (1998) 1.83
Aggressive behavioral phenotypes in mice. Behav Brain Res (2001) 1.80
Transgenic rat model of Huntington's disease. Hum Mol Genet (2003) 1.66
Regional distribution of Y-receptor subtype mRNAs in rat brain. Eur J Neurosci (1999) 1.66
Y-receptor subtypes--how many more? Trends Neurosci (1997) 1.55
Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology (1993) 1.43
Neuropharmacology of brain-stimulation-evoked aggression. Neurosci Biobehav Rev (1999) 1.41
The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y. Neurosci Biobehav Rev (2002) 1.41
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. Proc Natl Acad Sci U S A (2001) 1.37
Reduced anxiety and improved stress coping ability in mice lacking NPY-Y2 receptors. Eur J Neurosci (2003) 1.36
MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences. Behav Genet (2000) 1.34
Brain structures and neurotransmitters regulating aggression in cats: implications for human aggression. Prog Neuropsychopharmacol Biol Psychiatry (2001) 1.32
Serotonin receptors and animal models of aggressive behavior. Pharmacopsychiatry (1995) 1.30
Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells. J Neurochem (2003) 1.18
Role of hypothalamic neuropeptide Y in feeding and obesity. Neuropeptides (1999) 1.10
Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: evidence from Y2 receptor knockout mice. Behav Brain Res (2003) 1.09
Voluntary alcohol consumption is controlled via the neuropeptide Y Y1 receptor. J Neurosci (2002) 1.08
The neuropeptide Y (NPY) Y1 receptor subtype mediates NPY-induced antidepressant-like activity in the mouse forced swimming test. Neuropsychopharmacology (2002) 1.04
Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Brain Res Brain Res Rev (1998) 1.02
Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse. Neuroendocrinology (1999) 1.02
Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats. Endocrinology (1996) 1.01
Up-regulation of neuropeptide Y-Y2 receptors in an animal model of temporal lobe epilepsy. Mol Pharmacol (1998) 0.99
Potent neuropeptide Y Y1 receptor antagonist, 1229U91: blockade of neuropeptide Y-induced and physiological food intake. Endocrinology (1996) 0.98
The organization of intraspecific agonistic behaviour in the rat. Prog Neurobiol (1980) 0.95
Effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on locomotor activity and rearing of mice and rats. Psychopharmacology (Berl) (1990) 0.88
Neurotransmitter correlates of impulsive aggression in humans. Ann N Y Acad Sci (1996) 0.85
Olfactory bulb removal but not anosmia increases emotionality and mouse killing. Nature (1972) 0.83
Somatodendritic 5-HT(1A) autoreceptors mediate the anti-aggressive actions of 5-HT(1A) receptor agonists in rats: an ethopharmacological study with S-15535, alnespirone, and WAY-100635. Neuropsychopharmacology (2000) 0.82
Hormonal and neurochemical correlates of various forms of animal "aggression". Psychoneuroendocrinology (1992) 0.82
Behavioral profiles of genetically selected aggressive and nonaggressive male wild house mice in two anxiety tests. Behav Genet (2000) 0.82
Systemic 5-hydroxy-L-tryptophan down-regulates the arcuate CART mRNA level in rats. Regul Pept (2003) 0.82
Effects of neuropeptide Y on norepinephrine and serotonin metabolism in rat hypothalamus in vivo. Brain Res Bull (1989) 0.80
Regulation of neuropeptide Y in the rat amygdala following unilateral olfactory bulbectomy. Brain Res (2002) 0.80
Association of neuropeptide Y Y1 receptors with glutamate-positive and NPY-positive neurons in rat hippocampal cultures. Eur J Neurosci (2000) 0.79
An ethopharmacological analysis of the behavioral effects of 8-OH-DPAT. Psychopharmacology (Berl) (1993) 0.79
Regulation of neuropeptide Y gene expression in rat brain. Ann N Y Acad Sci (1990) 0.78
Neuropeptide Y selectively inhibits slow synaptic potentials in rat dorsal raphe nucleus in vitro by a presynaptic action. J Neurosci (1992) 0.78
Adaptive aspects of hormonal correlates of attack and defence in laboratory mice: a study in ethobiology. Prog Brain Res (1980) 0.78
Pharmacological studies on the monoaminergic influence on the synthesis and expression of neuropeptide Y and corticotropin releasing factor in rat brain amygdala. Neuropeptides (2001) 0.78
Effects of medial amygdaloid lesions on the initiation and the maintenance of muricide in olfactory bulbectomized rats. Physiol Behav (1982) 0.77
Serotonin release in the rat brain cortex is inhibited by neuropeptide Y but not affected by ACTH1-24, angiotensin II, bradykinin and delta-sleep-inducing peptide. Naunyn Schmiedebergs Arch Pharmacol (1991) 0.77
A method of quantitating aggressive behaviour revealing possible dissociation of motor activity and aggression. Psychopharmacology (Berl) (1979) 0.77
The involvement of neuropeptide Y in the antimuricide action of noradrenaline injected into the medial amygdala of olfactory bulbectomized rats. Pharmacol Biochem Behav (1987) 0.77
Gut hormone PYY(3-36) physiologically inhibits food intake. Nature (2002) 8.30
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J (2008) 4.28
Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome. Nat Med (2007) 3.36
Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metab (2006) 2.23
Epithelial and muscular regionalization of the human developing anorectum. Anat Rec (Hoboken) (2007) 2.23
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med (2007) 2.20
Hypothalamic Y2 receptors regulate bone formation. J Clin Invest (2002) 2.01
Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases. Brain (2010) 1.93
Behavioral phenotyping of mice in pharmacological and toxicological research. Exp Toxicol Pathol (2003) 1.85
Peptide YY is critical for acylethanolamine receptor Gpr119-induced activation of gastrointestinal mucosal responses. Cell Metab (2010) 1.71
Regional differences in distribution and functional expression of small-conductance Ca2+-activated K+ channels in rat brain. J Neurosci (2002) 1.70
NPY and Y receptors: lessons from transgenic and knockout models. Neuropeptides (2004) 1.63
Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone. Neuropsychopharmacology (2008) 1.53
Doxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse models. PLoS One (2010) 1.44
Breaking the seals: efficient mRNA detection from human archival paraffin-embedded tissue. RNA (2009) 1.43
The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y. Neurosci Biobehav Rev (2002) 1.41
Y4 receptor knockout rescues fertility in ob/ob mice. Genes Dev (2002) 1.38
Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice. Proc Natl Acad Sci U S A (2002) 1.37
Reduced anxiety and improved stress coping ability in mice lacking NPY-Y2 receptors. Eur J Neurosci (2003) 1.36
Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN. Cell Metab (2013) 1.33
The central and basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression. J Neurosci (2010) 1.29
Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci (2008) 1.28
Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminals. J Comp Neurol (2006) 1.28
Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus. J Neurochem (2005) 1.26
A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med (2005) 1.25
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Hum Mol Genet (2006) 1.25
Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3. PLoS Genet (2007) 1.24
Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Mol Endocrinol (2006) 1.18
c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action. J Clin Invest (2004) 1.18
Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells. J Neurochem (2003) 1.18
Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression. J Biol Chem (2007) 1.14
Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis. J Biol Chem (2007) 1.14
Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptors. Brain (2007) 1.13
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One (2013) 1.12
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease. Nephrol Dial Transplant (2011) 1.12
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets. PLoS One (2012) 1.12
Behavioural profile of a new mouse model for NPY deficiency. Eur J Neurosci (2008) 1.10
The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors. Eur J Neurosci (2005) 1.10
Hypothalamic control of bone formation: distinct actions of leptin and y2 receptor pathways. J Bone Miner Res (2005) 1.10
Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: evidence from Y2 receptor knockout mice. Behav Brain Res (2003) 1.09
The neuropeptide Y system: pathophysiological and therapeutic implications in obesity and cancer. Pharmacol Ther (2011) 1.09
Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo. J Immunol (2003) 1.08
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation. J Neurosci (2011) 1.08
Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males. Hum Mol Genet (2008) 1.07
GABA and its receptors in epilepsy. Adv Exp Med Biol (2004) 1.07
Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. Am J Pathol (2009) 1.05
Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight. PLoS One (2009) 1.04
Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures. Hippocampus (2003) 1.03
Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice. Mol Cell Biol (2003) 1.03
Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15. J Cachexia Sarcopenia Muscle (2012) 1.02
Neuropeptide Y and peptide YY: important regulators of energy metabolism. Curr Opin Endocrinol Diabetes Obes (2011) 1.02
Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease. J Neuropathol Exp Neurol (2010) 1.02
Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways. J Bone Miner Res (2006) 1.02
Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus. Neurobiol Dis (2006) 1.01
Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. J Histochem Cytochem (2007) 1.01
Behavioral profiling of NPY in aggression and neuropsychiatric diseases. Peptides (2006) 1.01
Behavioral and in vivo electrophysiological evidence for presymptomatic alteration of prefrontostriatal processing in the transgenic rat model for huntington disease. J Neurosci (2011) 1.01
NPY regulation of bone remodelling. Neuropeptides (2009) 0.99
Relevance of neuropeptide Y for the neuroimmune crosstalk. J Neuroimmunol (2003) 0.99
Functional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissues. Br J Pharmacol (2003) 0.98
Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. Diabetes (2002) 0.98