Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia.

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Published in Mol Cell Biol on March 01, 1996

Authors

A S Jun1, I A Trounce, M D Brown, J M Shoffner, D C Wallace

Author Affiliations

1: Department of Genetics and Molecular Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

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