Published in J Biol Chem on February 23, 1996
Deciphering the design of the tropomyosin molecule. Proc Natl Acad Sci U S A (2001) 2.14
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region. Biophys J (2001) 1.77
The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc Natl Acad Sci U S A (2002) 1.31
Structure and interactions of the carboxyl terminus of striated muscle alpha-tropomyosin: it is important to be flexible. Biophys J (2002) 1.22
Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T. Proc Natl Acad Sci U S A (2008) 1.20
The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. Mol Biol Cell (1999) 1.12
Tropomyosin regulates elongation by formin at the fast-growing end of the actin filament. Biochemistry (2007) 1.05
Tropomyosin ends determine the stability and functionality of overlap and troponin T complexes. Biophys J (2003) 1.04
A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin. J Biol Chem (2013) 1.04
Alteration of tropomyosin function and folding by a nemaline myopathy-causing mutation. Biophys J (2000) 0.96
A molecular evolution approach to study the roles of tropomyosin in fission yeast. PLoS One (2013) 0.94
Effects of tropomyosin internal deletion Delta23Tm on isometric tension and the cross-bridge kinetics in bovine myocardium. J Physiol (2003) 0.94
Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility. J Physiol (2004) 0.91
Regulation of nonmuscle myosin II by tropomyosin. Biochemistry (2014) 0.91
A peek into tropomyosin binding and unfolding on the actin filament. PLoS One (2009) 0.88
Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actin. FASEB J (2013) 0.84
Instability in the central region of tropomyosin modulates the function of its overlapping ends. Biophys J (2013) 0.79
Periodicities designed in the tropomyosin sequence and structure define its functions. Bioarchitecture (2013) 0.76
Evolutionarily conserved sites in yeast tropomyosin function in cell polarity, transport and contractile ring formation. Biol Open (2015) 0.76
Tropomyosin-binding properties modulate competition between tropomodulin isoforms. Arch Biochem Biophys (2016) 0.76
The cardiomyopathy-associated K15N mutation in tropomyosin alters actin filament pointed end dynamics. Arch Biochem Biophys (2017) 0.75
Deciphering the design of the tropomyosin molecule. Proc Natl Acad Sci U S A (2001) 2.14
Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin. Curr Biol (2001) 2.09
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region. Biophys J (2001) 1.77
Requirement of amino-terminal modification for striated muscle alpha-tropomyosin function. J Biol Chem (1994) 1.40
The structure of the N-terminus of striated muscle alpha-tropomyosin in a chimeric peptide: nuclear magnetic resonance structure and circular dichroism studies. Biochemistry (1998) 1.36
Conformational intermediates in the folding of a coiled-coil model peptide of the N-terminus of tropomyosin and alpha alpha-tropomyosin. Protein Sci (1993) 1.35
Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli. J Biol Chem (1987) 1.31
The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin. J Biol Chem (1988) 1.30
The amino terminus of muscle tropomyosin is a major determinant for function. J Biol Chem (1990) 1.13
Solution NMR structure and folding dynamics of the N terminus of a rat non-muscle alpha-tropomyosin in an engineered chimeric protein. J Mol Biol (2001) 1.09
The ends of tropomyosin are major determinants of actin affinity and myosin subfragment 1-induced binding to F-actin in the open state. Biochemistry (1999) 1.09
The stability of tropomyosin, a two-stranded coiled-coil protein, is primarily a function of the hydrophobicity of residues at the helix-helix interface. Biochemistry (1995) 1.09
Relationship between alternatively spliced exons and functional domains in tropomyosin. Proc Natl Acad Sci U S A (1991) 1.04
The effect of N-terminal acetylation on the structure of an N-terminal tropomyosin peptide and alpha alpha-tropomyosin. Protein Sci (1994) 1.03
Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function. Biochemistry (1997) 1.01
Actin assembly. Nature (1980) 0.98
Alteration of tropomyosin function and folding by a nemaline myopathy-causing mutation. Biophys J (2000) 0.96
The effects of deletion of the amino-terminal helix on troponin C function and stability. J Biol Chem (1994) 0.94
Modified calcium-dependent regulatory function of troponin C central helix mutants. J Biol Chem (1991) 0.94
Tropomyosin lysine reactivities and relationship to coiled-coil structure. Biochemistry (1985) 0.92
Synthesis of a troponin C cDNA and expression of wild-type and mutant proteins in Escherichia coli. J Biol Chem (1988) 0.90
The sequence of the alternatively spliced sixth exon of alpha-tropomyosin is critical for cooperative actin binding but not for interaction with troponin. J Biol Chem (1997) 0.88
Investigation of the structural requirements of the troponin C central helix for function. Biochemistry (1995) 0.87
Independent functions for the N- and C-termini in the overlap region of tropomyosin. Biochemistry (2000) 0.87
Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants. Biochemistry (1999) 0.86
Effects of mutations in the central helix of troponin C on its biological activity. J Biol Chem (1991) 0.86
Restricted expression of the actin-regulatory protein, tropomyosin, defines distinct boundaries, evaginating neuroepithelium, and choroid plexus forerunners during early CNS development. J Neurosci (1996) 0.85
Mutations in the N- and D-helices of the N-domain of troponin C affect the C-domain and regulatory function. Biophys J (1999) 0.83
Incorporation of microinjected mutant and wildtype recombinant tropomyosins into stress fibers in fibroblasts. Cell Motil Cytoskeleton (1993) 0.79
Analysis of the regulatory and structural defects of troponin C central helix mutants. Biochemistry (1991) 0.77
Structural and functional significance of aspartic acid 89 of the troponin C central helix in Ca2+ signaling. Biochemistry (1996) 0.77
Isolation and characterization of a tropomyosin binding protein from human blood platelets. J Biol Chem (1985) 0.76
Synthesis of cDNAs from synthetic oligonucleotides using troponin C as an example. Methods Enzymol (1991) 0.75
Platelet tropomyosin binding protein is identical with serum albumin. J Biol Chem (1985) 0.75