Published in J Physiol on November 01, 1995
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science (1989) 40.22
Movements of labelled calcium in squid giant axons. J Physiol (1957) 18.75
Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem (1993) 10.95
Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science (1995) 6.91
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature (1993) 5.69
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol (1993) 5.64
The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins. Nature (1995) 4.96
Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science (1995) 4.25
G proteins. Trends Biochem Sci (1992) 3.79
Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate. Cell (1993) 3.53
Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties. Nature (1993) 3.43
Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (1994) 3.21
Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits. Nature (1992) 2.88
Is the multidrug transporter a flippase? Trends Biochem Sci (1992) 2.68
Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J Biol Chem (1995) 2.62
Genetic determination of exocrine pancreatic function in cystic fibrosis. Am J Hum Genet (1992) 2.48
Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C. Nature (1992) 2.47
Ion fluxes across the pulmonary epithelium and the secretion of lung liquid in the foetal lamb. J Physiol (1974) 2.32
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature (1992) 2.31
Calcium and hormone action. Annu Rev Physiol (1994) 2.11
Contact pressures in the human hip joint measured in vivo. Proc Natl Acad Sci U S A (1986) 2.09
Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell (1992) 2.09
AN ION TRANSPORT DEFECT IN ERYTHROCYTES FROM UREMIC PATIENTS. Trans Assoc Am Physicians (1964) 2.04
ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope. Cell (1995) 1.97
Actin filaments regulate epithelial Na+ channel activity. Am J Physiol (1991) 1.93
Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells. J Biol Chem (1990) 1.86
Membrane mechanisms and intracellular signalling in cell volume regulation. Int Rev Cytol (1995) 1.86
Production of a severe cystic fibrosis mutation in mice by gene targeting. Nat Genet (1993) 1.80
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature (1993) 1.79
The role of amiloride-blockable sodium transport in adrenaline-induced lung liquid reabsorption in the fetal lamb. J Physiol (1986) 1.77
Membrane-bound ATP fuels the Na/K pump. Studies on membrane-bound glycolytic enzymes on inside-out vesicles from human red cell membranes. J Gen Physiol (1981) 1.57
Low-conductance K channels in apical membrane of rat cortical collecting tubule. Am J Physiol (1989) 1.48
Cyclic ADP-ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells. EMBO J (1994) 1.46
Regulation of ROMK1 K+ channel activity involves phosphorylation processes. Proc Natl Acad Sci U S A (1994) 1.46
Retracted Cloning and functional expression of a rat heart KATP channel. Nature (1994) 1.42
Renal potassium channels and their regulation. Annu Rev Physiol (1992) 1.42
Calcium-hydrogen exchange by the plasma membrane Ca-ATPase of voltage-clamped snail neurons. Proc Biol Sci (1993) 1.33
Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels. EMBO J (1995) 1.30
Membrane compartmentalized ATP and its preferential use by the Na,K-ATPase of human red cell ghosts. J Gen Physiol (1977) 1.25
Absorptive and secretory functions of the perfused rat cauda epididymidis. J Physiol (1978) 1.23
Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency. EMBO J (1995) 1.21
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis. Pflugers Arch (1994) 1.17
Electrogenic anion secretion in cultured rat epididymal epithelium. J Physiol (1986) 1.15
ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C. FEBS Lett (1989) 1.13
Chloride transport by high-resistance heterocellular epithelia. Physiol Rev (1991) 1.11
Activation of epithelial Na+ channels by protein kinase A requires actin filaments. Am J Physiol (1993) 1.08
The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine study. J Physiol (1995) 0.98
cAMP-activated chloride channel in the basolateral membrane of the thick ascending limb of the mouse kidney. J Membr Biol (1990) 0.98
Luminal acidification by the perfused rat cauda epididymidis. J Physiol (1980) 0.98
Homeostatic muffling. Nature (1991) 0.97
Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: evidence against direct drug extrusion from the plasma membrane. Proc Natl Acad Sci U S A (1994) 0.96
A small-conductance Cl- channel in the mouse thick ascending limb that is activated by ATP and protein kinase A. J Physiol (1995) 0.95
Region-specific activity of the plasma membrane Ca2+ pump and delayed activation of Ca2+ entry characterize the polarized, agonist-evoked Ca2+ signals in exocrine cells. J Biol Chem (1995) 0.92
Membrane potentials and intracellular Cl- activity of toad skin epithelium in relation to activation and deactivation of the transepithelial Cl- conductance. J Membr Biol (1986) 0.91
ADH increases apical Na+, K+, 2Cl- entry in mouse medullary thick ascending limbs of Henle. Am J Physiol (1987) 0.91
Ion transport by mitochondria-rich cells in toad skin. J Membr Biol (1987) 0.90
Comparative physiology of sweating. Br J Dermatol (1973) 0.89
Localization of chloride conductance to mitochondria-rich cells in frog skin epithelium. J Membr Biol (1986) 0.89
Ion channels in the thick ascending limb of Henle's loop. Ren Physiol Biochem (1990) 0.88
cAMP increases the basolateral Cl- -conductance in the isolated perfused medullary thick ascending limb of Henle's loop of the mouse. Pflugers Arch (1985) 0.87
G protein-regulated large-conductance chloride channels in freshly isolated fetal type II alveolar epithelial cells. Am J Physiol (1993) 0.86
Extracellular ATP can activate autonomic signal transduction pathways in cultured equine sweat gland epithelial cells. J Exp Biol (1994) 0.86
External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism. J Biol Chem (1994) 0.86
Chloride currents of single mitochondria-rich cells of toad skin epithelium. J Physiol (1994) 0.85
Cl- channels in basolateral renal medullary membranes: III. Determinants of single-channel activity. J Membr Biol (1990) 0.81
The effect of prolonged oligohydramnios on fetal lung development, maturation and ventilatory patterns in the newborn guinea pig. J Dev Physiol (1987) 0.81
Conductive cation transport in apical membrane vesicles prepared from fetal lung. Biochim Biophys Acta (1994) 0.80
Cyclic AMP-and beta-agonist-activated chloride conductance of a toad skin epithelium. J Physiol (1992) 0.78
Functional consequences of the membrane pool of ATP associated with the human red blood cell Na/K pump. Prog Clin Biol Res (1988) 0.78