| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals.
|
Am J Med Genet
|
1987
|
3.57
|
|
2
|
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.
|
Am J Hum Genet
|
1992
|
3.33
|
|
3
|
A multilocus genotyping assay for candidate markers of cardiovascular disease risk.
|
Genome Res
|
1999
|
2.13
|
|
4
|
Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis.
|
Am J Hum Genet
|
1996
|
1.50
|
|
5
|
Intima-media thickness and diameter of carotid and femoral arteries in children, adolescents and adults from the Stanislas cohort: effect of age, sex, anthropometry and blood pressure.
|
J Hypertens
|
1998
|
1.29
|
|
6
|
Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.
|
Neurobiol Aging
|
2000
|
1.24
|
|
7
|
Apolipoprotein E: an important gene and protein to follow in laboratory medicine.
|
Clin Chem
|
1995
|
1.20
|
|
8
|
Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients.
|
J Neurochem
|
1998
|
1.11
|
|
9
|
Apolipoprotein E serum concentration and polymorphism in six European countries: the ApoEurope Project.
|
Atherosclerosis
|
2000
|
1.06
|
|
10
|
Apolipoprotein E polymorphism and serum concentration in Alzheimer's disease in nine European centres: the ApoEurope study. ApoEurope group.
|
Clin Chem Lab Med
|
2000
|
1.04
|
|
11
|
A multilocus genotyping assay for cardiovascular disease.
|
Clin Chem Lab Med
|
1998
|
1.01
|
|
12
|
Multivariate genetic analysis of high density lipoprotein particles.
|
Atherosclerosis
|
1992
|
1.00
|
|
13
|
Objectives, design and recruitment of a familial and longitudinal cohort for studying gene-environment interactions in the field of cardiovascular risk: the Stanislas cohort.
|
Clin Chem Lab Med
|
1998
|
1.00
|
|
14
|
Genetics strongly determines the wall thickness of the left and right carotid arteries.
|
Hum Genet
|
1998
|
0.98
|
|
15
|
Serum myeloperoxidase concentration in a healthy population: biological variations, familial resemblance and new genetic polymorphisms.
|
Eur J Hum Genet
|
2001
|
0.97
|
|
16
|
The effect of variation in the apolipoprotein B gene on plasmid lipid and apolipoprotein B levels. I. A likelihood-based approach to cladistic analysis.
|
Ann Hum Genet
|
1994
|
0.96
|
|
17
|
An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data.
|
Am J Hum Genet
|
1989
|
0.95
|
|
18
|
Metabolic determinants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations: a family study with part of the Stanislas Cohort.
|
Arterioscler Thromb Vasc Biol
|
1998
|
0.94
|
|
19
|
Biological and genetic factors influencing plasma factor VIII levels in a healthy family population: results from the Stanislas cohort.
|
Br J Haematol
|
2005
|
0.93
|
|
20
|
Biological variations and genetic reference values for apolipoprotein E serum concentrations: results from the STANISLAS cohort study.
|
Clin Chem
|
1998
|
0.93
|
|
21
|
DNA polymorphisms of the apoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease: European Atherosclerosis Research Study.
|
Atherosclerosis
|
1995
|
0.92
|
|
22
|
Genetic and environmental influences on left ventricular mass. A family study.
|
Hypertension
|
2000
|
0.91
|
|
23
|
Conformation of apolipoprotein E both in free and in lipid-bound form may determine the avidity of triglyceride-rich lipoproteins to the LDL receptor: structural and kinetic study.
|
Biochim Biophys Acta
|
2000
|
0.91
|
|
24
|
Family study of lipoprotein lipase gene polymorphisms and plasma triglyceride levels.
|
Genet Epidemiol
|
1996
|
0.91
|
|
25
|
Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry.
|
FEBS Lett
|
1998
|
0.90
|
|
26
|
Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors.
|
J Lipid Res
|
1996
|
0.88
|
|
27
|
Genetic influences on lipid metabolism trait variability within the Stanislas Cohort.
|
J Lipid Res
|
2001
|
0.87
|
|
28
|
Relationship between E-selectin L/F554 polymorphism and blood pressure in the Stanislas cohort.
|
Hum Genet
|
2000
|
0.87
|
|
29
|
LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women.
|
Eur J Clin Invest
|
2001
|
0.86
|
|
30
|
Frequencies of five genetic polymorphisms in coronarographed patients and effects on lipid levels in a supposedly healthy population.
|
Clin Genet
|
1996
|
0.86
|
|
31
|
Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease.
|
J Neurol Sci
|
1997
|
0.85
|
|
32
|
[Glutathione S-transferases genetic polymorphisms and human diseases: overview of epidemiological studies].
|
Ann Biol Clin (Paris)
|
2004
|
0.83
|
|
33
|
A comparison of lifestyle, genetic, bioclinical and biochemical variables of offspring with and without family histories of premature coronary heart disease: the experience of the European Atherosclerosis Research Studies.
|
J Cardiovasc Risk
|
1999
|
0.83
|
|
34
|
Apolipoprotein E polymorphisms and concentration in chronic diseases and drug responses.
|
Clin Chem Lab Med
|
2000
|
0.83
|
|
35
|
[Apolipoprotein E polymorphism in a Moroccan population: allele frequency and relation to plasma lipid concentrations].
|
Ann Biol Clin (Paris)
|
2002
|
0.81
|
|
36
|
Apolipoprotein E4, lipoprotein lipase C447 and angiotensin-I converting enzyme deletion alleles were not associated with increased wall thickness of carotid and femoral arteries in healthy subjects from the Stanislas cohort.
|
Atherosclerosis
|
1998
|
0.81
|
|
37
|
Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels.
|
Diabetes
|
1991
|
0.80
|
|
38
|
Effect of apo E phenotype on plasma postprandial triglyceride levels in young male adults with and without a familial history of myocardial infarction: the EARS II study. European Atherosclerosis Research Study.
|
Atherosclerosis
|
1999
|
0.80
|
|
39
|
Apo B signal peptide insertion/deletion polymorphism is involved in postprandial lipoparticles' responses.
|
Atherosclerosis
|
1995
|
0.80
|
|
40
|
Protein-lipid interactions in reconstituted high density lipoproteins: apolipoprotein and cholesterol influence.
|
Chem Phys Lipids
|
2001
|
0.80
|
|
41
|
Combined effects of lipoprotein lipase and apolipoprotein E polymorphisms on lipid and lipoprotein levels in the Stanislas cohort.
|
J Lipid Res
|
1997
|
0.79
|
|
42
|
Associations of apolipoprotein E concentration and polymorphism with lipids and apolipoprotein levels in Chinese from Beijing and Shanghai.
|
Clin Chem Lab Med
|
2000
|
0.79
|
|
43
|
Apolipoprotein E-epsilon 4 allele and Alzheimer's disease.
|
Lancet
|
1993
|
0.78
|
|
44
|
Association of apolipoprotein E allele epsilon 4 with late-onset sporadic Alzheimer's disease.
|
Am J Med Genet
|
1994
|
0.78
|
|
45
|
Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms.
|
Hum Genet
|
2001
|
0.78
|
|
46
|
Two polymorphisms for amino acid substitutions in the APOA4 gene.
|
Nucleic Acids Res
|
1990
|
0.78
|
|
47
|
Structural peculiarities of the binding of very low density lipoproteins and low density lipoproteins to the LDL receptor in hypertriglyceridemia: role of apolipoprotein E.
|
Biochim Biophys Acta
|
2000
|
0.78
|
|
48
|
A parametric copula model for analysis of familial binary data.
|
Am J Hum Genet
|
1999
|
0.78
|
|
49
|
Characterization and quantification of serum lipoprotein subfractions by capillary isotachophoresis: relationships with lipid, apolipoprotein, and lipoprotein levels.
|
J Lipid Res
|
1999
|
0.78
|
|
50
|
Pharmacogenomics and drug response in cardiovascular disorders.
|
Pharmacogenomics
|
2004
|
0.77
|
|
51
|
Effects of apo B and apo E gene polymorphisms on lipid and apolipoprotein concentrations after a test meal.
|
Clin Chim Acta
|
1996
|
0.77
|
|
52
|
Two-dimensional electrophoresis of plasma proteins and high density lipoproteins during inflammation.
|
Electrophoresis
|
1989
|
0.77
|
|
53
|
Familial resemblance of plasma apolipoprotein B: the Nancy study.
|
Genet Epidemiol
|
1990
|
0.77
|
|
54
|
Association of apolipoprotein E polymorphism and concentration with serum lipids and apolipoprotein level in the Chinese from Shanghai.
|
Clin Chem Lab Med
|
1998
|
0.77
|
|
55
|
Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease.
|
Neurosci Lett
|
1998
|
0.77
|
|
56
|
Apolipoproteins E and C-III in apo B- and non-apo B-containing lipoproteins in middle-aged women from the Stanislas cohort: effect of oral contraceptive use and common apolipoprotein E polymorphism.
|
Atherosclerosis
|
2001
|
0.76
|
|
57
|
Lipoprotein lipase (C/G)447 polymorphism and blood pressure in the Stanislas Cohort.
|
J Hypertens
|
2000
|
0.76
|
|
58
|
Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population.
|
Clin Chem Lab Med
|
2001
|
0.76
|
|
59
|
Sources of variability of human plasma apolipoprotein A-IV levels and relationships with lipid metabolism.
|
Genet Epidemiol
|
1994
|
0.76
|
|
60
|
Apolipoprotein E level in cerebrospinal fluid increases with aging.
|
J Am Geriatr Soc
|
1997
|
0.76
|
|
61
|
Immunochemical study of the plasma low and high density lipoproteins in Tangier disease.
|
FEBS Lett
|
1986
|
0.75
|
|
62
|
Plasma apolipoproteins in Tangier disease, as studied with two-dimensional electrophoresis.
|
Clin Chem
|
1987
|
0.75
|
|
63
|
Study of the sequence tagged site (STS) in the beginning of human apo A4 gene region.
|
Nucleic Acids Res
|
1990
|
0.75
|
|
64
|
High-resolution separation of PCR product and gene diagnosis by Capillary gel electrophoresis.
|
Biomed Chromatogr
|
1996
|
0.75
|
|
65
|
DNA polymorphisms of human apolipoprotein A-IV gene: frequency and effects on lipid, lipoprotein and apolipoprotein levels in a French population.
|
Clin Genet
|
1994
|
0.75
|
|
66
|
Lipid and lipoprotein genetic variability: an important contribution from the French health examination centers.
|
Clin Biochem
|
1995
|
0.75
|
|
67
|
Which are the best tools for specific clinical application (chips, multiplex, mass spec profile, etc.)?
|
Clin Chem Lab Med
|
2003
|
0.75
|
|
68
|
The frequency of the factor V gene R506Q mutation varies between regions of France.
|
Nouv Rev Fr Hematol
|
1995
|
0.75
|
|
69
|
Molecular pharmacophore determination of lipid lowering drugs with the receptor mapping method.
|
Mini Rev Med Chem
|
2002
|
0.75
|
|
70
|
Environmental and genetic determinants of intima-media thickness of the carotid artery.
|
Clin Exp Pharmacol Physiol
|
2001
|
0.75
|
|
71
|
The role of genetics in defining reference values and health status.
|
Methods Inf Med
|
1993
|
0.75
|
|
72
|
Multilocus approach to cardiovascular risk.
|
Scand J Clin Lab Invest Suppl
|
1999
|
0.75
|
|
73
|
[Alzheimer disease: hypotheses implicating apolipoproteins E].
|
Presse Med
|
1996
|
0.75
|
|
74
|
APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort).
|
Clin Genet
|
2001
|
0.75
|
|
75
|
Biological factors affecting concentrations of serum LpAI lipoprotein particles in serum, and determination of reference limits.
|
Clin Chem
|
1990
|
0.75
|
|
76
|
[Association between E-selectin Leu554Phe polymorphism and blood pressure in the Stanislas cohort].
|
Arch Mal Coeur Vaiss
|
2001
|
0.75
|
|
77
|
High sensitivity of laser-induced fluorescence detection in capillary gel electrophoresis for accurate apolipoprotein E genotyping.
|
Biotechniques
|
1997
|
0.75
|
|
78
|
[Factors of variation and reference intervals for serum GST activity: the Stanislas cohort study].
|
Ann Biol Clin (Paris)
|
2004
|
0.75
|
|
79
|
Evaluation of lipoproteins and apolipoproteins in serum of a Tangier patient by micro-scale two-dimensional electrophoresis.
|
Clin Chem
|
1987
|
0.75
|
|
80
|
Variations in apolipoproteins serum amyloid A, A-I, A-II, and C-III in severely head-injured patients.
|
J Clin Chem Clin Biochem
|
1990
|
0.75
|
|
81
|
A rapid and reliable method for direct genotyping of codon 360 in the human apolipoprotein A-IV gene.
|
J Lipid Res
|
1992
|
0.75
|
|
82
|
Sample size calculations for classical association and TDT-type methods using family data.
|
Ann Hum Genet
|
2001
|
0.75
|
|
83
|
[Application of bidimensional electrophoresis in the determination of genetic variants].
|
Ann Biol Clin (Paris)
|
1988
|
0.75
|
|
84
|
Apolipoprotein E genotype epsilon 4/epsilon 2 in the STANISLAS Cohort Study--dominance of the epsilon 2 allele?
|
Ann Hum Genet
|
1996
|
0.75
|
|
85
|
[APOC3, CETP, beta-fibrinogen and MTHFR are genetic determinants of carotid intim-media thickness (Stanislas cohort)].
|
Arch Mal Coeur Vaiss
|
2001
|
0.75
|
|
86
|
Which, and how limited number of polymorphisms should be selected per disease, risk assessment, health profile or biological system?
|
Clin Chem Lab Med
|
2003
|
0.75
|
|
87
|
Capillary electrophoretic analysis of recombinant human apolipoprotein E. Calibration mode of a protein reference material.
|
J Chromatogr A
|
1999
|
0.75
|