Published in Am J Hum Genet on June 01, 1996
Sequence diversity in 36 candidate genes for cardiovascular disorders. Am J Hum Genet (1999) 3.02
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From an ACE polymorphism to genome-wide searches for eQTL. J Clin Invest (2013) 0.80
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No association between angiotensin I converting enzyme (ACE) I/D polymorphism and gastric cancer risk among Japanese. Nagoya J Med Sci (2011) 0.79
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Association of circulating angiotensin converting enzyme activity with respiratory muscle function in infants. Respir Res (2010) 0.75
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Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet (1992) 3.33
Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem (1991) 3.22
Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N Engl J Med (1994) 3.11
The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am J Hum Genet (1988) 2.85
Combined linkage and segregation analysis using regressive models. Am J Hum Genet (1988) 2.33
Plasma angiotensin-converting enzyme activity and carotid wall thickening. Circulation (1994) 2.18
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Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study. Am J Hum Genet (1988) 1.98
Conclusions of segregation analysis for family data generated under two-locus models. Am J Hum Genet (1993) 1.67
Gene expression and tissue localization of the two isoforms of angiotensin I converting enzyme. Hypertension (1993) 1.29
Distribution of plasma angiotensin I-converting enzyme levels in healthy men: relationship to environmental and hormonal parameters. J Lab Clin Med (1991) 1.23
The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme. FEBS Lett (1989) 1.22
Automated kinetic assay of angiotensin-converting enzyme in serum. Clin Chem (1986) 1.17
Detection of a major gene for heterocellular hereditary persistence of fetal hemoglobin after accounting for genetic modifiers. Am J Hum Genet (1994) 1.15
Cloning and expression of an evolutionary conserved single-domain angiotensin converting enzyme from Drosophila melanogaster. J Biol Chem (1995) 1.11
Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction. Circulation (1994) 1.07
Testing for association between disease and linked marker loci: a log-linear-model analysis. Am J Hum Genet (1991) 1.05
Insertion/deletion (I/D) polymorphism at the locus for angiotensin I-converting enzyme and myocardial infarction. Clin Genet (1993) 0.96
Segregation and linkage analysis of serum angiotensin I-converting enzyme levels: evidence for two quantitative-trait loci. Am J Hum Genet (1995) 0.95
Functional analysis of the human somatic angiotensin I-converting enzyme gene promoter. Biochem J (1993) 0.84
Functional study of the germinal angiotensin I-converting enzyme promoter. Biochem Biophys Res Commun (1992) 0.81
Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure. A quantitative trait locus confers identical complex phenotypes in human and rat hypertension. Circulation (1995) 0.81
An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest (1990) 10.35
Molecular basis of human hypertension: role of angiotensinogen. Cell (1992) 6.07
PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res (1992) 3.95
Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats. Nature (1991) 3.74
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet (1992) 3.33
Protective role of interleukin-10 in atherosclerosis. Circ Res (1999) 3.28
A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Hum Genet (2004) 3.24
Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem (1991) 3.22
Sequence diversity in 36 candidate genes for cardiovascular disorders. Am J Hum Genet (1999) 3.02
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation (2005) 2.77
Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler Thromb Vasc Biol (2009) 2.71
Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis. Circulation (1999) 2.56
Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension (1994) 2.41
Circulating cell adhesion molecules and death in patients with coronary artery disease. Circulation (2001) 2.37
A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res (1999) 2.13
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Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study. Am J Hum Genet (1988) 1.98
Hypertriglyceridaemia as a risk factor of coronary heart disease mortality in subjects with impaired glucose tolerance or diabetes. Results from the 11-year follow-up of the Paris Prospective Study. Diabetologia (1989) 1.96
Relationships between angiotensin I converting enzyme gene polymorphism, plasma levels, and diabetic retinal and renal complications. Diabetes (1994) 1.85
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Cox proportional hazards survival regression in haplotype-based association analysis using the Stochastic-EM algorithm. Eur J Hum Genet (2004) 1.73
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Pulsatile versus steady component of blood pressure: a cross-sectional analysis and a prospective analysis on cardiovascular mortality. Hypertension (1989) 1.72
Prognostic value of plasma tissue factor and tissue factor pathway inhibitor for cardiovascular death in patients with coronary artery disease: the AtheroGene study. J Thromb Haemost (2007) 1.67
Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes. J Biol Chem (1991) 1.65
Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy. Diabetologia (1995) 1.57
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Reliability of reported family history of myocardial infarction. BMJ (1993) 1.52
Pulmonary arterial hypertension associated with fenfluramine exposure: report of 109 cases. Eur Respir J (2007) 1.51
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New polymorphisms in the interleukin-10 gene--relationships to myocardial infarction. Eur J Clin Invest (2001) 1.50
Testing association between candidate-gene markers and phenotype in related individuals, by use of estimating equations. Am J Hum Genet (1997) 1.47
Molecular biology and genetics of the angiotensin-I-converting enzyme: potential implications in cardiovascular diseases. Cardiovasc Res (1996) 1.43
New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation. Arterioscler Thromb Vasc Biol (2000) 1.42
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Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension. Thorax (2004) 1.40
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Angiotensinogen: a candidate gene involved in preeclampsia? Nat Genet (1993) 1.37
Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease. Q J Med (1994) 1.36
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Gene expression and tissue localization of the two isoforms of angiotensin I converting enzyme. Hypertension (1993) 1.29
Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow. Circ Res (1996) 1.29
The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk. J Hypertens (1997) 1.27
Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. Hum Mol Genet (1997) 1.24
Identification of polymorphisms in the promoter and the 3' region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled. Blood (2001) 1.24
Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease. Neurobiol Aging (2000) 1.24
APOE genotype, ethnicity, and the risk of cerebral hemorrhage. Neurology (2008) 1.24
Haemostatic factors and the risk of cardiovascular death in patients with coronary artery disease: the AtheroGene study. Arterioscler Thromb Vasc Biol (2006) 1.23
The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme. FEBS Lett (1989) 1.22
Sequence polymorphisms in the apolipoprotein(a) gene and their association with lipoprotein(a) levels and myocardial infarction. The ECTIM Study. Atherosclerosis (1999) 1.22
Lack of relationship between an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients. Diabetes (1995) 1.20
Apolipoprotein E: an important gene and protein to follow in laboratory medicine. Clin Chem (1995) 1.20
Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease. Arterioscler Thromb Vasc Biol (2001) 1.18
Polymorphisms of the tumour necrosis factor-alpha gene, coronary heart disease and obesity. Eur J Clin Invest (1998) 1.18
Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations-the ECTIM study. Hum Mol Genet (2000) 1.18
Lack of association between polymorphisms of eight candidate genes and idiopathic dilated cardiomyopathy: the CARDIGENE study. J Am Coll Cardiol (2000) 1.18
Study of V(1)-vascular vasopressin receptor gene microsatellite polymorphisms in human essential hypertension. J Mol Cell Cardiol (2000) 1.16
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The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction. Hum Mol Genet (1998) 1.15
Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation (1996) 1.14
Polymorphisms of the human matrix gla protein (MGP) gene, vascular calcification, and myocardial infarction. Arterioscler Thromb Vasc Biol (2000) 1.14
Genetic determination of plasma aldosterone levels in essential hypertension. Am J Hypertens (1998) 1.14
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Is the relationship between blood pressure and cardiovascular risk dependent on body mass index? Am J Epidemiol (1985) 1.13
Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci U S A (1994) 1.11
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Cloning and expression of an evolutionary conserved single-domain angiotensin converting enzyme from Drosophila melanogaster. J Biol Chem (1995) 1.11
Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients. J Neurochem (1998) 1.11
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Confirmation of associations between ion channel gene SNPs and QTc interval duration in healthy subjects. Eur J Hum Genet (2007) 1.08
TLR4/Asp299Gly, CD14/C-260T, plasma levels of the soluble receptor CD14 and the risk of coronary heart disease: The PRIME Study. Eur J Hum Genet (2004) 1.07
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