Published in J Trauma on June 01, 1996
IL-6 predicts organ dysfunction and mortality in patients with multiple injuries. Scand J Trauma Resusc Emerg Med (2009) 1.25
Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion. Shock (2009) 1.17
Systemic lidocaine shortens length of hospital stay after colorectal surgery: a double-blinded, randomized, placebo-controlled trial. Ann Surg (2007) 1.16
Pathophysiology of the systemic inflammatory response after major accidental trauma. Scand J Trauma Resusc Emerg Med (2009) 1.08
Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma. Ann Surg (1999) 1.00
Parenteral nutrition maintains pulmonary IgA antibody transport capacity, but not active transport, following injury. Am J Surg (2009) 0.92
Mechanism of neutrophil recruitment to the lung after pulmonary contusion. Shock (2011) 0.92
CpG-ODN and MPLA prevent mortality in a murine model of post-hemorrhage-Staphyloccocus aureus pneumonia. PLoS One (2010) 0.87
Immune response of severely injured patients--influence of surgical intervention and therapeutic impact. Langenbecks Arch Surg (2007) 0.87
Facts and fiction: the impact of hypothermia on molecular mechanisms following major challenge. Mediators Inflamm (2012) 0.87
Innate immune response to pulmonary contusion: identification of cell type-specific inflammatory responses. Shock (2012) 0.85
Injury induces localized airway increases in pro-inflammatory cytokines in humans and mice. Surg Infect (Larchmt) (2010) 0.84
Proinflammatory cytokine surge after injury stimulates an airway immunoglobulin a increase. J Trauma (2010) 0.83
Protocol for a randomized controlled trial on risk adapted damage control orthopedic surgery of femur shaft fractures in multiple trauma patients. Trials (2009) 0.81
The soluble tumor necrosis factor receptor I is an early predictor of local infective complications after colorectal surgery. J Clin Immunol (2002) 0.79
Is the function of alveolar macrophages altered following blunt chest trauma? Langenbecks Arch Surg (2011) 0.78
Association of tumor necrosis factor β genetic polymorphism and sepsis susceptibility. Exp Ther Med (2011) 0.77
Bilirubin is an antioxidant of possible physiological importance. Science (1987) 11.26
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J Exp Med (1995) 4.57
Analytical gel isotachophoresis of proteins with carrier ampholyte spacers. Ann N Y Acad Sci (1973) 4.09
Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci U S A (1988) 3.42
Antioxidant activity of albumin-bound bilirubin. Proc Natl Acad Sci U S A (1987) 3.35
Biochemistry and pathology of radical-mediated protein oxidation. Biochem J (1997) 3.14
Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation. J Biol Chem (1994) 2.20
Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood (1995) 2.20
Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients. Crit Care Med (2000) 2.19
High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors. Proc Natl Acad Sci U S A (1992) 2.15
The health of smokers' and nonsmokers' children. J Allergy (1969) 2.07
Impaired erythropoiesis after haemorrhagic shock in mice is associated with erythroid progenitor apoptosis in vivo. Acta Anaesthesiol Scand (2008) 2.04
Regulation of interleukin 8 gene expression by oxidant stress. J Biol Chem (1993) 2.02
Presence of hypochlorite-modified proteins in human atherosclerotic lesions. J Clin Invest (1996) 2.01
Soluble tumor necrosis factor receptors correlate with parasitemia and disease severity in human malaria. J Infect Dis (1992) 1.98
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations. Science (1999) 1.95
Control of severe hemorrhage using C-clamp and pelvic packing in multiply injured patients with pelvic ring disruption. J Orthop Trauma (2001) 1.93
Interleukin-8, interleukin-6, and soluble tumour necrosis factor receptor type I release from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus. Immunology (1994) 1.81
Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition. Proc Natl Acad Sci U S A (1985) 1.79
Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor alpha, and interleukin-6 levels in rheumatoid arthritis. Longitudinal evaluation during methotrexate and azathioprine therapy. Arthritis Rheum (1993) 1.79
Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J Cereb Blood Flow Metab (2000) 1.78
Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. Neurology (2005) 1.76
Ultrasound in blunt abdominal and thoracic trauma. J Trauma (1993) 1.75
Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence. Methods Enzymol (1994) 1.68
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees. J Exp Med (1994) 1.64
Alteration of monocyte function following major injury. Arch Surg (1988) 1.64
Liver ischemia and reperfusion induces a systemic inflammatory response through Kupffer cell activation. Shock (1996) 1.63
T cells involved in psoriasis vulgaris belong to the Th1 subset. J Invest Dermatol (1994) 1.62
Plasma total bilirubin levels predict amputation events in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetologia (2013) 1.61
Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol (1990) 1.58
Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis. Blood (1997) 1.58
Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity. J Biol Chem (1991) 1.57
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages. Biochem J (1993) 1.55
Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury. Neurology (2010) 1.55
Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage. Am J Physiol (1991) 1.52
Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. Crit Care Med (1997) 1.50
Interleukin-6: a sensitive parameter for the early diagnosis of neonatal bacterial infection. Pediatrics (1994) 1.49
Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII. J Biol Chem (1998) 1.48
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque. Biochem J (1998) 1.45
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding. J Pediatr (1995) 1.45
Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J (1992) 1.43
[The abdominal compartment syndrome]. Unfallchirurg (2001) 1.41
Incidence of septic complications and multiple organ failure in severely injured patients is sex specific. J Trauma (2000) 1.40
IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-alpha, TGF-beta1 and blood-brain barrier function. J Neuroimmunol (1999) 1.39
Differential expression of proinflammatory cytokines and their inhibitors during the course of meningococcal infections. J Infect Dis (1994) 1.37
Predominance of Th1-type T cells in synovial fluid of patients with Yersinia-induced reactive arthritis. Eur J Immunol (1992) 1.36
Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor). Circ Shock (1992) 1.36
Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. Mol Psychiatry (1997) 1.35
Endotoxin and cytokine profile in plasma of baboons challenged with lethal and sublethal Escherichia coli. Circ Shock (1991) 1.35
Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Arterioscler Thromb Vasc Biol (1995) 1.34
Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. Biochem J (1994) 1.33
Incidence and clinical pattern of the abdominal compartment syndrome after "damage-control" laparotomy in 311 patients with severe abdominal and/or pelvic trauma. Crit Care Med (2000) 1.32
Immunologic detection and measurement of hypochlorite-modified LDL with specific monoclonal antibodies. Arterioscler Thromb Vasc Biol (1995) 1.32
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria. Am J Pathol (1998) 1.32
A field study of the effects of elevated CO(2) on plant biomass and community structure in a calcareous grassland. Oecologia (1999) 1.32
Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes. J Biol Chem (1994) 1.32
Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta (1992) 1.31
Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin. Cytokine (1990) 1.30
Systemic levels of the T cell regulatory cytokines IL-10 and IL-12 in Bechçet's disease; soluble TNFR-75 as a biological marker of disease activity. J Rheumatol (1997) 1.29
Evaluation of a test system for measuring cytokine production in human whole blood cell cultures. J Immunol Methods (1991) 1.28
Relationship of interleukin-10 plasma levels to severity of injury and clinical outcome in injured patients. J Trauma (1997) 1.28
Roles of histamine, complement and xanthine oxidase in thermal injury of skin. Am J Pathol (1989) 1.27
Resource patch formation and exploitation throughout the marine microbial food web. Am Nat (2009) 1.27
The gut: a cytokine-generating organ in systemic inflammation? Shock (1995) 1.25
Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases. Proc Natl Acad Sci U S A (1990) 1.25
Patterns of proinflammatory cytokines and inhibitors during typhoid fever. J Infect Dis (1994) 1.23
Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain. Kidney Int (1997) 1.22
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia (1996) 1.21
Posterior elbow dislocation with associated vascular injury after blunt trauma. J Trauma (1999) 1.20
[Horseradish peroxidase: kinetic studies and optimization of peroxidase activity determination using the substrates H2O2 and 3,3',5,5'-tetramethylbenzidine]. J Clin Chem Clin Biochem (1985) 1.20
Hemorrhage and resuscitation: immunological aspects. Am J Physiol (1990) 1.20
ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol. J Biol Chem (2001) 1.16
Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group. Immunology (1992) 1.16
S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury. J Neurotrauma (2001) 1.15
The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis. Arthritis Rheum (2001) 1.15
Tocopherol-mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement. FASEB J (1999) 1.14
Oxidative stress and the redox status of malaria-infected erythrocytes. Blood Cells (1990) 1.14
Evaluation of interleukin-6 and soluble receptors of tumor necrosis factor for early diagnosis of neonatal infection. J Pediatr (1996) 1.13
Requirement for, promotion, or inhibition by alpha-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic Biol Med (1997) 1.13
Radical-induced chain oxidation of proteins and its inhibition by chain-breaking antioxidants. Biochem J (1993) 1.13
Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets. J Mol Med (Berl) (2006) 1.12
Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome. J Lab Clin Med (1990) 1.12
Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes. Shock (1996) 1.11
Efflux of hepatic ascorbate: a potential contributor to the maintenance of plasma vitamin C. Biochem J (1999) 1.11
Antioxidant activities of bile pigments: biliverdin and bilirubin. Methods Enzymol (1990) 1.11