Published in Biochem Biophys Res Commun on April 05, 1996
Soy isoflavones reduce heat shock proteins in experimental atherosclerosis. Eur J Nutr (2005) 0.75
What do commercial ginseng preparations contain? Lancet (1994) 2.94
Reading the medical record. I. Analysis of physicians' ways of reading the medical record. Comput Methods Programs Biomed (1993) 2.60
Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci U S A (1996) 2.48
Influence of pravastatin, a specific inhibitor of HMG-CoA reductase, on hepatic metabolism of cholesterol. N Engl J Med (1990) 2.06
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest (2001) 1.95
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase. J Biol Chem (1996) 1.80
Multicentre study of a new enzymatic method of cholesterol determination. J Clin Chem Clin Biochem (1984) 1.77
Comparison of the effects of prostaglandins E 1, E 2 and F 2 alpha on the sympathetically stimulated rabbit heart. Acta Physiol Scand (1971) 1.77
The antioxidant butylated hydroxytoluene protects against atherosclerosis. Arterioscler Thromb (1991) 1.67
Dependence of the metabolism of nitric oxide (NO) in healthy human whole blood on the oxygenation of its red cell haemoglobin. Br J Pharmacol (1992) 1.67
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J Biol Chem (1998) 1.65
Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid. J Clin Invest (1980) 1.64
Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum. J Clin Invest (1982) 1.61
The impact of hormone replacement therapy on quality of life and willingness to pay. Br J Obstet Gynaecol (1997) 1.58
Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment. J Lipid Res (1995) 1.57
Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. Circ Res (1993) 1.53
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res (2000) 1.51
Urinary albumin excretion and heart rate variability in obese women. Int J Obes Relat Metab Disord (1998) 1.44
Generation of viable cholesterol-free mice. Science (2003) 1.43
Omega-hydroxylation of steriod side-chain in biosynthesis of bile acids. Eur J Biochem (1973) 1.40
Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme. Eur J Biochem (1994) 1.40
Increased nerve stimulation induced release of noradrenaline from the rabbit heart after inhibition of prostaglandin synthesis. Acta Physiol Scand (1971) 1.38
Effects of intermittent treatment with aspirin on thromboxane and prostacyclin formation in patients with acute myocardial infarction. Lancet (1988) 1.38
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J Biol Chem (1997) 1.36
Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro. J Biol Chem (1997) 1.34
Simple diagnosis of the Zellweger syndrome by gas-liquid chromatography of dimethylacetals. J Lipid Res (1986) 1.32
Inhibition by prostaglandin E2 of sympathetic neurotransmission in the rabbit heart. Acta Physiol Scand (1970) 1.32
Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc Natl Acad Sci U S A (1994) 1.31
Formation of cholic acid from 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes. J Lipid Res (1983) 1.27
Biosynthesis of bile acids in man. Hydroxylation of the C27-steroid side chain. J Clin Invest (1975) 1.27
Both physical fitness and acute exercise regulate nitric oxide formation in healthy humans. J Appl Physiol (1985) (1997) 1.25
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone. Proc Natl Acad Sci U S A (1997) 1.25
Influence of indomethacin and of prostaglandin E1 on total and regional blood flow in man. Acta Physiol Scand (1978) 1.23
Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans. Arterioscler Thromb Vasc Biol (1996) 1.23
Nicotine stimulates prostaglandin formation in the rabbit heart. Br J Pharmacol (1977) 1.22
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver. Biochim Biophys Acta (1993) 1.21
Mechanism of microbial transformation of cholesterol into coprostanol. Eur J Biochem (1971) 1.21
Orchidectomy versus oestrogen for prostatic cancer: cardiovascular effects. Br Med J (Clin Res Ed) (1986) 1.20
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia. J Physiol (1987) 1.20
Individual bile acids in portal venous and systemic blood serum of fasting man. Gastroenterology (1977) 1.20
Mitochondrial omega-hydroxylation of cholesterol side chain. J Biol Chem (1974) 1.19
Prednisolone excretion in human milk. J Pediatr (1985) 1.19
Costs of coronary heart disease and stroke: the case of Sweden. J Intern Med (1999) 1.18
Endogenous prostaglandins as local regulators of blood flow in man: effect of indomethacin on reactive and functional hyperaemia. J Physiol (1976) 1.18
Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall. Biochim Biophys Acta (1985) 1.18
Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways. J Biol Chem (1998) 1.16
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res (2001) 1.16
Assay and properties of a mitochondrial 25-hydroxylase active on vitamine D3. J Biol Chem (1978) 1.15
Plasma nitrate as an index of nitric oxide formation in man: analyses of kinetics and confounding factors. Clin Physiol (1996) 1.15
25-Hydroxylase activity in subcellular fractions from human liver. Evidence for different rates of mitochondrial hydroxylation of vitamin D2 and D3. Scand J Clin Lab Invest (1986) 1.14
Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med (1994) 1.14
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA. J Biol Chem (1997) 1.14
Studies on mechanisms controlling the secretion of neurotransmitters in the rabbit heart. Acta Physiol Scand Suppl (1971) 1.13
The bile acid synthetic gene 3beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis. J Clin Invest (2000) 1.13
Influence of indomethacin on the systemic and pulmonary vascular resistance in man. Clin Sci Mol Med (1978) 1.12
Oxidation of branched-chain fatty acids in rat liver homogenates. Eur J Biochem (1970) 1.12
Properties of a reconstituted vitamin D3 25-hydroxylase from rat liver mitochondria. J Biol Chem (1980) 1.11
Characterization of enzymes involved in formation of ethyl esters of long-chain fatty acids in humans. J Lipid Res (2001) 1.10
Tetrasomy 15q: two marker chromosomes with no detectable alpha-satellite DNA. Am J Hum Genet (1994) 1.09
Effects of nicotine on cardiac prostaglandin and platelet thromboxane synthesis. Br J Pharmacol (1978) 1.09
Expression, purification, and enzymatic properties of recombinant human cytochrome P450c27 (CYP27). Arch Biochem Biophys (1997) 1.08
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases. Neurosci Lett (2000) 1.08
Postprandial serum bile acids in healthy man. Evidence for differences in absorptive pattern between individual bile acids. Gut (1977) 1.08
Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin. J Lipid Res (1999) 1.08
Identification of intracellular factor XIII in human monocytes and macrophages. J Clin Invest (1985) 1.07
Conversion of inhaled nitric oxide to nitrate in man. Br J Pharmacol (1995) 1.06
Effect of prostaglandin synthesis inhibitors on basal and carbon dioxide stimulated cerebral blood flow in man. Acta Physiol Scand (1983) 1.06
Sensitive kinetic bioluminescent assay of glycerol release from human fat cells. J Lipid Res (1981) 1.06
7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase. Eur J Biochem (1994) 1.06
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. Neurosci Lett (2001) 1.05
4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. Int J Clin Pharmacol Ther (2009) 1.05
Hypoxia causes prostaglandin release from perfused rabbit hearts. Acta Physiol Scand (1974) 1.05
Coronary flow regulation in patients with ischemic heart disease: release of purines and prostacyclin and the effect of inhibitors of prostaglandin formation. Circulation (1985) 1.05
Assay of the major bile acids in serum by isotope dilution-mass spectrometry. Scand J Clin Lab Invest (1983) 1.05
Estrogen therapy and liver function--metabolic effects of oral and parenteral administration. Prostate (1989) 1.05
Peroxisomal dysfunction in a boy with neurologic symptoms and amaurosis (Leber disease): clinical and biochemical findings similar to those observed in Zellweger syndrome. J Pediatr (1986) 1.05
Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease. Neuroreport (2000) 1.04
Expression and characterization of a C24 bile acid 7 alpha-dehydratase from Eubacterium sp. strain VPI 12708 in Escherichia coli. J Lipid Res (1996) 1.04
Effect of exercise on human arterial and regional venous plasma concentrations of prostaglandin E. Prostaglandins Med (1978) 1.04
Facilitation of sympathetic neurotransmission in the cat spleen after inhibition of prostaglandin synthesis. Acta Physiol Scand (1971) 1.04
Preferential secretion of newly formed noradrenaline in the perfused rabbit heart. Acta Physiol Scand (1970) 1.04
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells. J Lipid Res (1997) 1.03
On the mechanism of the enzymatic conversn of cholest-5-ene-3-beta, 7-alpha-diol into 7-alpha-hydroxycholest-4-en-3-one. Eur J Biochem (1969) 1.03
Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway. Biochem Biophys Res Commun (2007) 1.03
On the release of prostaglandin E2 from the rabbit heart following infusion of noradrenaline. Acta Physiol Scand (1973) 1.02
Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase. Biochemistry (1993) 1.02
Reading the medical record. II. Design of a human-computer interface for basic reading of computerized medical records. Comput Methods Programs Biomed (1993) 1.02
The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man. FEBS Lett (1991) 1.02
Factor XIII (fibrin stabilising factor) in Henoch-Schönlein's purpura. Acta Paediatr Scand (1977) 1.02
Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J Clin Invest (1996) 1.02
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J Intern Med (2011) 1.02
Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis. J Clin Invest (1986) 1.01
14C-triolein breath test as a rapid and convenient screening test for fat malabsorption. Scand J Gastroenterol (1983) 1.01
Lipoprotein oxidation and progression of carotid atherosclerosis. Circulation (1997) 1.00
Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study. J Lipid Res (2001) 1.00
Phosphatidylethanol formation in rat organs after ethanol treatment. Biochim Biophys Acta (1984) 1.00
Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface. J Lipid Res (2000) 1.00
Mechamism and stereochemistry of the enzymatic conversion of a delta 4-3-oxosteroid into a 3-oxo-5alpha-steroid. Eur J Biochem (1969) 1.00