Published in Dev Biol on July 10, 1996
GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev (1998) 4.72
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development (2009) 4.25
Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation. Mol Cell Biol (2003) 3.69
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet (2008) 3.37
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J (1997) 3.35
The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes Dev (1997) 3.33
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell (2009) 3.31
Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev (2002) 3.12
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol (2008) 2.34
Control of ground-state pluripotency by allelic regulation of Nanog. Nature (2012) 2.25
A serum response factor-dependent transcriptional regulatory program identifies distinct smooth muscle cell sublineages. Mol Cell Biol (1997) 2.20
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest (2007) 2.12
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol Cell Biol (1998) 2.05
GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol Cell Biol (1998) 2.00
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol (2005) 2.00
Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Mol Cell Biol (1999) 1.95
Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc Natl Acad Sci U S A (1999) 1.86
FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped. Proc Natl Acad Sci U S A (1999) 1.83
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A (2005) 1.70
Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. J Clin Invest (2011) 1.67
Lung development: orchestrating the generation and regeneration of a complex organ. Development (2014) 1.66
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth. Circ Res (2011) 1.62
Gata6 is an important regulator of mouse pancreas development. Dev Biol (2006) 1.58
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc Natl Acad Sci U S A (1997) 1.56
Cardiogenic differentiation and transdifferentiation of progenitor cells. Circ Res (2008) 1.54
GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis. J Clin Invest (2006) 1.47
Efficient derivation of alveolar type II cells from embryonic stem cells for in vivo application. Tissue Eng Part A (2009) 1.46
Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol (2005) 1.46
Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells. BMC Dev Biol (2007) 1.45
Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature (2013) 1.42
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res (2012) 1.38
Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors. EMBO J (1997) 1.37
Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol (2006) 1.35
Structure and specificity of GATA proteins in Th2 development. Mol Cell Biol (2001) 1.34
Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa. BMC Gastroenterol (2008) 1.28
Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell (2013) 1.27
Abnormalities of the genitourinary tract in female mice lacking GATA5. Mol Cell Biol (2000) 1.26
Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development (2014) 1.26
Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes. Reprod Biol Endocrinol (2005) 1.21
Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma. Proc Natl Acad Sci U S A (2012) 1.12
Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription. J Cell Biol (2002) 1.12
Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice. J Biol Chem (2009) 1.12
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell (2014) 1.12
Identification of GATA6 sequence variants in patients with congenital heart defects. Pediatr Res (2010) 1.10
Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8. Mol Cell Biol (2007) 1.10
Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis. Dev Dyn (2008) 1.10
Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev (2014) 1.09
LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding. Mol Cell Biol (2005) 1.08
Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development (2012) 1.08
Epithelial lineages of the small intestine have unique patterns of GATA expression. J Mol Histol (2005) 1.08
All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms. PLoS One (2010) 1.07
Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair. J Clin Invest (2002) 1.06
Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages. Dev Biol (2014) 1.05
Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia. PLoS One (2009) 1.05
Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9. Mol Cell Biol (2008) 1.04
Gene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis. Nucleic Acids Res (2002) 1.01
Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis. Exp Hematol (2008) 1.00
Regulation of myosin light chain kinase and telokin expression in smooth muscle tissues. Am J Physiol Cell Physiol (2006) 0.99
Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development (2011) 0.99
A mouse model of uterine leiomyosarcoma. Am J Pathol (2004) 0.99
Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis. PLoS Genet (2014) 0.98
Down-regulation of retinoic acid receptor alpha signaling is required for sacculation and type I cell formation in the developing lung. J Biol Chem (2003) 0.97
Differential transcriptional analysis between red and white skeletal muscle of Chinese Meishan pigs. Int J Biol Sci (2010) 0.95
Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells. Nat Protoc (2013) 0.94
Activation of the control reporter plasmids pRL-TK and pRL-SV40 by multiple GATA transcription factors can lead to aberrant normalization of transfection efficiency. BMC Biotechnol (2004) 0.93
The GATA factor revolution in hematology. Blood (2017) 0.90
Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan. PLoS One (2007) 0.90
Transcriptional mechanisms underlying hemoglobin synthesis. Cold Spring Harb Perspect Med (2013) 0.90
Identification of a novel marker for primordial smooth muscle and its differential expression pattern in contractile vs noncontractile cells. J Cell Biol (1997) 0.88
A positive GATA element and a negative vitamin D receptor-like element control atrial chamber-specific expression of a slow myosin heavy-chain gene during cardiac morphogenesis. Mol Cell Biol (1998) 0.88
Whole exome sequencing identifies de novo mutations in GATA6 associated with congenital diaphragmatic hernia. J Med Genet (2014) 0.88
Expression pattern of the Ets-related transcription factor Elf-1. Mol Med (1998) 0.87
GATA6 is a crucial regulator of Shh in the limb bud. PLoS Genet (2014) 0.87
Hmga2 is required for canonical WNT signaling during lung development. BMC Biol (2014) 0.87
GATA factors in gastrointestinal malignancy. World J Surg (2011) 0.87
Molecular characterization of lung dysplasia induced by c-Raf-1. PLoS One (2009) 0.86
Reciprocal changes in the expression of transcription factors GATA-4 and GATA-6 accompany adrenocortical tumorigenesis in mice and humans. Mol Med (1999) 0.86
GATA-6 and NF-κB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contraction. Mol Cell Biol (2012) 0.86
Transcriptional repression of Caveolin-1 (CAV1) gene expression by GATA-6 in bladder smooth muscle hypertrophy in mice and human beings. Am J Pathol (2011) 0.85
Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells. Stem Cells Int (2010) 0.84
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling. J Biol Chem (2010) 0.84
The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma. Int J Clin Exp Pathol (2009) 0.83
GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1. Am J Physiol Cell Physiol (2008) 0.83
Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
GATA-1 dominantly activates a program of erythroid gene expression in factor-dependent myeloid FDCW2 cells. Mol Cell Biol (1998) 0.83
VEGF and IHH rescue definitive hematopoiesis in Gata-4 and Gata-6-deficient murine embryoid bodies. Exp Hematol (2009) 0.83
Calcineurin initiates smooth muscle differentiation in neural crest stem cells. J Cell Biol (2004) 0.82
Novel and functional DNA sequence variants within the GATA6 gene promoter in ventricular septal defects. Int J Mol Sci (2014) 0.82
Unilateral cryptorchidism induces morphological changes of testes and hyperplasia of Sertoli cells in a dog. Lab Anim Res (2014) 0.80
Afzelin attenuates asthma phenotypes by downregulation of GATA3 in a murine model of asthma. Mol Med Rep (2015) 0.80
Comparative molecular developmental aspects of the mammalian- and the avian lungs, and the insectan tracheal system by branching morphogenesis: recent advances and future directions. Front Zool (2012) 0.79
Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators. Sci Rep (2016) 0.79
Spontaneously differentiated GATA6-positive human embryonic stem cells represent an important cellular step in human embryonic development; they are not just an artifact of in vitro culture. Stem Cells Dev (2013) 0.79
The emerging role of GATA transcription factors in development and disease. Expert Rev Mol Med (2016) 0.79
Unique functions of Gata4 in mouse liver induction and heart development. Dev Biol (2015) 0.78
A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice. BMC Dev Biol (2015) 0.78
Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Sci Signal (2015) 0.78
Maintenance of pluripotency in mouse ES cells without Trp53. Sci Rep (2013) 0.78
Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats. Exp Lung Res (2009) 0.78
Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease. Neonatology (2010) 0.77
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev (1997) 5.51
GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev (1998) 4.72
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell (2001) 4.60
Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev (2001) 3.52
The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes Dev (1997) 3.33
Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mech Dev (1998) 3.04
Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem (2001) 2.57
A serum response factor-dependent transcriptional regulatory program identifies distinct smooth muscle cell sublineages. Mol Cell Biol (1997) 2.20
Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development (2001) 2.15
Structure and expression of a smooth muscle cell-specific gene, SM22 alpha. J Biol Chem (1995) 2.05
PlexinA2 and semaphorin signaling during cardiac neural crest development. Development (2001) 2.02
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Coordinate transcription of variant surface glycoprotein genes and an expression site associated gene family in Trypanosoma brucei. Cell (1985) 1.92
GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev Biol (1997) 1.83
An invasive cleavage assay for direct quantitation of specific RNAs. Nat Biotechnol (2001) 1.79
Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science (1995) 1.77
Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Mol Cell Biol (2001) 1.74
Expression of recombinant genes in myocardium in vivo after direct injection of DNA. Circulation (1990) 1.72
The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol (1994) 1.70
Emergence of fatal avian influenza in New England harbor seals. MBio (2012) 1.70
GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily. J Biol Chem (1997) 1.66
Migration of cardiac neural crest cells in Splotch embryos. Development (2000) 1.43
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Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c-ret. J Clin Invest (2000) 1.37
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Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J Clin Invest (1995) 1.29
A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle. Mol Cell Biol (1994) 1.29
The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm. J Biol Chem (2000) 1.28
Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor. J Biol Chem (2000) 1.26
Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus. Proc Natl Acad Sci U S A (1994) 1.25
Transgenic rescue of congenital heart disease and spina bifida in Splotch mice. Development (1999) 1.25
An essential role for connexin43 gap junctions in mouse coronary artery development. Development (2002) 1.24
Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice. Proc Natl Acad Sci U S A (1993) 1.23
Mice overexpressing genes from the 22q11 region deleted in velo-cardio-facial syndrome/DiGeorge syndrome have middle and inner ear defects. Hum Mol Genet (2001) 1.19
Length dependence of Ca2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C. J Physiol (1995) 1.09
Developmental pattern of expression and genomic organization of the calponin-h1 gene. A contractile smooth muscle cell marker. J Biol Chem (1996) 1.08
Binding of serum response factor to CArG box sequences is necessary but not sufficient to restrict gene expression to arterial smooth muscle cells. J Biol Chem (2001) 1.03
Protein synthesis and degradation during starvation-induced cardiac atrophy in rabbits. Circ Res (1987) 1.00
Developmental analysis and subcellular localization of the murine homologue of ELL. Proc Natl Acad Sci U S A (1997) 0.98
The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU.1, and a novel transcription factor. Mol Cell Biol (1996) 0.97
Establishment and characterization of a megakaryoblast cell line with amplification of MLL. Leukemia (1998) 0.90
Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo. J Clin Invest (1997) 0.88
Expression pattern of the Ets-related transcription factor Elf-1. Mol Med (1998) 0.87
Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy. Mol Ther (2000) 0.87
SM22alpha promoter targets gene expression to vascular smooth muscle cells in vitro and in vivo. Mol Med (2000) 0.86
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