T Funahashi

Author PubWeight™ 173.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999 14.25
2 Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000 9.85
3 Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001 9.53
4 Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1. DNA Res 1999 7.39
5 Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 2000 6.96
6 Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3. DNA Res 1998 6.79
7 cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996 5.40
8 Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000 5.36
9 PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001 5.18
10 Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001 4.82
11 Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000 4.46
12 Abdominal fat: standardized technique for measurement at CT. Radiology 1999 4.25
13 Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001 3.61
14 Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med 1996 3.02
15 Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001 2.73
16 An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res 2000 2.59
17 Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci 1999 2.44
18 Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut 2005 2.03
19 The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. J Biol Chem 1993 1.93
20 Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation. Kidney Int 2006 1.87
21 The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab 2001 1.82
22 Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3 (supplement). DNA Res 1998 1.81
23 Genomic structure and mutations in adipose-specific gene, adiponectin. Int J Obes Relat Metab Disord 2000 1.60
24 Marked hypocholesterolemia in a case with adrenal adenoma--enhanced catabolism of low density lipoprotein (LDL) via the LDL receptors of tumor cells. J Clin Endocrinol Metab 1995 1.43
25 Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem Biophys Res Commun 2001 1.36
26 Effect of visceral fat accumulation on uric acid metabolism in male obese subjects: visceral fat obesity is linked more closely to overproduction of uric acid than subcutaneous fat obesity. Metabolism 1998 1.33
27 Circulating adiponectin levels are reduced in nonobese but insulin-resistant first-degree relatives of type 2 diabetic patients. Diabetes 2003 1.28
28 Aquaporin adipose, a putative glycerol channel in adipocytes. J Biol Chem 2000 1.28
29 The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction. Heart 2003 1.24
30 Complementation of apolipoprotein B mRNA editing by human liver accompanied by secretion of apolipoprotein B48. J Biol Chem 1994 1.23
31 Effects of probucol on xanthomata regression in familial hypercholesterolemia. Am J Cardiol 1986 1.23
32 Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein. Nucleic Acids Res 1994 1.20
33 Genetic structure, isolation and characterization of a Bacillus licheniformis cell wall hydrolase. Mol Gen Genet 1992 1.13
34 Enhancement of the aquaporin adipose gene expression by a peroxisome proliferator-activated receptor gamma. J Biol Chem 2001 1.11
35 Activation of monocytes in vivo causes intracellular accumulation of lipoprotein-derived lipids and marked hypocholesterolemia--a possible pathogenesis of necrobiotic xanthogranuloma. Atherosclerosis 1999 1.09
36 Visceral fat accumulation contributes to insulin resistance, small-sized low-density lipoprotein, and progression of coronary artery disease in middle-aged non-obese Japanese men. Jpn Circ J 2001 1.08
37 Visceral fat is a major contributor for multiple risk factor clustering in Japanese men with impaired glucose tolerance. Diabetes Care 2001 1.08
38 Plasma adiponectin concentration before and after successful kidney transplantation. Transplant Proc 2003 1.07
39 Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel. J Biol Chem 2001 1.06
40 Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial. Diabetes Res Clin Pract 2001 1.04
41 Two decades of annual medical examinations in Japanese obese children: do obese children grow into obese adults? Int J Obes Relat Metab Disord 1997 1.01
42 Galectin-12, an Adipose-expressed Galectin-like Molecule Possessing Apoptosis-inducing Activity. J Biol Chem 2001 0.98
43 Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation. Hepatology 1998 0.98
44 Effects of soy protein diet on the expression of adipose genes and plasma adiponectin. Horm Metab Res 2003 0.97
45 mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action. Int J Obes (Lond) 2009 0.96
46 REPR and complementation factor(s) interact to modulate rat apolipoprotein B mRNA editing in response to alterations in cellular cholesterol flux. J Lipid Res 1994 0.93
47 Multicenter study on the effects of day care therapy on schizophrenia: a comparison of day care patients with outpatients. Psychiatry Clin Neurosci 1999 0.93
48 Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet. Gut 2008 0.92
49 Adsorption of anti-dsDNA antibodies by immobilized polyanionic compounds. Clin Exp Immunol 1990 0.92
50 Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program. Diabet Med 2012 0.91
51 The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease. Obes Res 2001 0.90
52 Troglitazone suppresses intimal formation following balloon injury in insulin-resistant Zucker fatty rats. Atherosclerosis 1998 0.89
53 Autoimmune hyperchylomicronemia. N Engl J Med 1989 0.89
54 Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa). Biochim Biophys Acta 1992 0.89
55 Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte-derived macrophages. Arterioscler Thromb Vasc Biol 1998 0.88
56 Maternal soluble tumour necrosis factor receptor type 2 (sTNFR2) and adiponectin are both related to blood pressure during gestation and infant's birthweight. Clin Endocrinol (Oxf) 2004 0.87
57 Selective removal of anti-double-stranded DNA antibodies by immunoadsorption with dextran sulphate in a patient with systemic lupus erythematosus. Ann Rheum Dis 1989 0.87
58 Characterization of the human apobec-1 gene: expression in gastrointestinal tissues determined by alternative splicing with production of a novel truncated peptide. J Lipid Res 1997 0.86
59 Cloning and sequencing of the Vibrio parahaemolyticus fur gene. Microbiol Immunol 1997 0.86
60 Magnitude of sustained multiple risk factors for ischemic heart disease in Japanese employees: a case-control study. Jpn Circ J 2001 0.86
61 Analysis of a recycling-impaired mutant of low density lipoprotein receptor in familial hypercholesterolemia. J Biol Chem 1989 0.85
62 Plasma leptin levels and body fat distribution. Horm Metab Res 1996 0.84
63 Importance of intra-abdominal visceral fat accumulation to coronary atherosclerosis in heterozygous familial hypercholesterolaemia. Int J Obes Relat Metab Disord 1997 0.84
64 Cloning and characterization of the rat apobec-1 gene: a comparative analysis of gene structure and promoter usage in rat and mouse. J Lipid Res 1997 0.84
65 Plasma adiponectin levels in women with anorexia nervosa. Horm Metab Res 2003 0.83
66 Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy. Diabetologia 2005 0.82
67 Insulin-mediated regulation of decidual protein induced by progesterone (DEPP) in adipose tissue and liver. Horm Metab Res 2009 0.82
68 A point mutation of low-density-lipoprotein receptor causing rapid degradation of the receptor. Eur J Biochem 1992 0.82
69 Decreased affinity of low density lipoprotein (LDL) particles for LDL receptors in patients with cholesteryl ester transfer protein deficiency. Eur J Clin Invest 1995 0.82
70 Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis. Atherosclerosis 1988 0.82
71 Effectiveness of the Kampo kami-shoyo-san (TJ-24) for tremor of antipsychotic-induced parkinsonism. Psychiatry Clin Neurosci 2000 0.81
72 Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbits. Hum Gene Ther 1996 0.81
73 Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells. Biochim Biophys Acta 1992 0.80
74 Selective reduction of cholesterol in HDL2 fraction by probucol in familial hypercholesterolemia and hyperHDL2 cholesterolemia with abnormal cholesteryl ester transfer. Am J Cardiol 1988 0.80
75 A novel system of LDL apheresis combining a centrifugal plasma separator with a specific LDL adsorption column. Atherosclerosis 1988 0.80
76 Characteristics of coronary artery disease and lipoprotein abnormalities in patients with heterozygous familial hypercholesterolemia associated with diabetes mellitus or impaired glucose tolerance. Atherosclerosis 1997 0.79
77 [Mitral regurgitation: detection and quantitative evaluation by two-dimensional Doppler echocardiography]. J Cardiogr 1985 0.79
78 Clinical features of familial hypercholesterolemia. Arteriosclerosis 1989 0.79
79 Frequency of intron 14 splicing defect of cholesteryl ester transfer protein gene in the Japanese general population--relation between the mutation and hyperalphalipoproteinemia. Atherosclerosis 1993 0.79
80 Assignment of the gene encoding the human apolipoprotein B mRNA editing enzyme (APOBEC1) to chromosome 12p13.1. Genomics 1994 0.79
81 Identification and characterization of the sodA genes encoding manganese superoxide dismutases in Vibrio parahaemolyticus, Vibrio mimicus, and Vibrio vulnificus. Microbiol Immunol 2001 0.78
82 Periodic ACTH discharge. J Pediatr 1980 0.78
83 Troglitazone enhances glucose uptake and inhibits mitogen-activated protein kinase in human aortic smooth muscle cells. Atherosclerosis 1998 0.78
84 Hypocholesterolaemic factor from gallbladder cancer cells. Lancet 1990 0.78
85 Polydisperse low-density lipoproteins in hyperalphalipoproteinemic chronic alcohol drinkers in association with marked reduction of cholesteryl ester transfer protein activity. Metabolism 1992 0.78
86 Low-density lipoproteins in hyperalphalipoproteinemic heavy alcohol drinkers have reduced affinity for the low-density lipoprotein receptor. Clin Biochem 1992 0.77
87 Non-macrophage-related accumulation of cholesterol during probucol treatment in familial hypercholesterolemia: report of two cases. Atherosclerosis 1992 0.77
88 Left atrial myxoma metastasizing to the aorta, with intraluminal growth causing renovascular hypertension. Cardiology 1991 0.77
89 Rapid enhancement of acyl-CoA synthetase, LPL, and GLUT-4 mRNAs in adipose tissue of VMH rats. Am J Physiol 1996 0.77
90 A novel nonsense mutation (G181X) in the human cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects. J Lipid Res 1996 0.76
91 [On the microaneurysms on the bulbar conjunctiva]. Nihon Ganka Kiyo 1966 0.76
92 Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise. Am J Physiol 1993 0.76
93 A single point mutation in the splice donor site of the low-density-lipoprotein-receptor gene produces intron read-through, exon-skipped and cryptic-site-utilized transcripts. Eur J Biochem 1995 0.76
94 Common mutations in the low-density-lipoprotein-receptor gene causing familial hypercholesterolemia in the Japanese population. Arterioscler Thromb Vasc Biol 1995 0.76
95 Mutation in bombesin receptor subtype-3 gene is not a major cause of obesity in the Japanese. Horm Metab Res 2000 0.76
96 [The vital staining of the eye (author's transl)]. Nippon Ganka Gakkai Zasshi 1980 0.75
97 A novel point mutation in a splice acceptor site of intron 1 of the human low density lipoprotein receptor gene which causes severe hypercholesterolemia: an unexpected absence of exon skipping. Mutations in brief no. 139. Online. Hum Mutat 1998 0.75
98 Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages. Biochem J 1997 0.75
99 Nafamostat is hydrolysed by human liver cytosolic long-chain acyl-CoA hydrolase. Xenobiotica 2007 0.75
100 Poor responsiveness of heart rate to treadmill exercise in vasospastic angina. Clin Cardiol 1985 0.75
101 Increased serum remnant lipoproteins in patients with apolipoprotein E7 (apo E Suita). Atherosclerosis 1997 0.75
102 Tangier disease with continuous massive and longitudinal diffuse calcification in the coronary arteries : demonstration by the sagittal images of intravascular ultrasonography. Circulation 2000 0.75
103 Extralysosomal degradation of high-density lipoproteins in a human hepatoma cell line, Mahlavu. Biochim Biophys Acta 1993 0.75
104 Suppression of splenic enzyme activities by administration of aminopeptidase N (CD13) inhibitors: relationship between actions in vivo and in vitro. J Enzyme Inhib 1994 0.75
105 Relationship between LDL receptor activity and development of coronary heart disease in Japanese cases with heterozygous familial hypercholesterolemia. Artery 1987 0.75
106 [Molecular mechanism of energy regulation in adipose tissues]. Nihon Rinsho 2001 0.75
107 Standardization of bovine E-rosette assay and enumeration of lymphocyte subpopulations. Nihon Juigaku Zasshi 1984 0.75
108 [LDL receptor abnormality]. Tanpakushitsu Kakusan Koso 1988 0.75
109 Cells of an internalization-defective familial hypercholesterolemia mutant secrete low density lipoprotein receptors. J Biochem 1987 0.75
110 [Studies on aqueous outlets. Part II. Histopathological investigation on the influence of indocyanine green dye to the ocular tissues (author's transl)]. Nippon Ganka Gakkai Zasshi 1976 0.75
111 A 31-year-old woman with homozygous familial hypercholesterolemia without significant lesions in the coronary arteries. Atherosclerosis 1986 0.75
112 Diagnosis of vasospastic angina by analysis of heart rate response to exercise: effects of different levels of work load. Angiology 1985 0.75
113 [Recent trend in the research of hyperlipidemia in Japan. Three mutations including two deletions of the low density lipoprotein receptor gene in Japanese patients with homozygous familial hypercholesterolemia]. Nihon Naika Gakkai Zasshi 1989 0.75
114 Low-density lipoprotein receptor mutation that deletes exons 2 and 3 by Alu-Alu recombination. J Biochem 1993 0.75
115 [Determination of triiodothyronine by RIA-MATT3 kit (author's transl)]. Radioisotopes 1977 0.75
116 [Studies of aqueous outlets. Report 1. Infrared absorption photography of aqueous outlets in animals (author's transl)]. Nippon Ganka Gakkai Zasshi 1976 0.75
117 [Clinical and experimental studies on chronic bronchitis-with special reference to bronchoscopic findings, observation on biopsy specimens, and electric resistance of bronchial mucosa]. Nihon Kyobu Shikkan Gakkai Zasshi 1975 0.75
118 [Tne extraction of lens dislocated into the vitreous]. Nippon Ganka Gakkai Zasshi 1973 0.75
119 Antithymic antibodies in schizophrenic sera. Biol Psychiatry 1982 0.75
120 [Determination of thyroxine in serum by gammacoat T4 (author's transl)]. Radioisotopes 1978 0.75
121 Abnormal heart rate control in vasospastic angina: effects of calcium antagonists. Int J Cardiol 1985 0.75
122 [Determination of TSH in serum by GammaDab TSH kit (author's transl)]. Radioisotopes 1979 0.75
123 [Subconjunctival lipoma]. Nihon Ganka Kiyo 1967 0.75
124 [Tuberculoma of the orbital apex]. Nihon Ganka Kiyo 1967 0.75
125 [Obesity and diabetes mellitus]. Nihon Naika Gakkai Zasshi 1996 0.75
126 [Obesity and diseases. 4. Molecular mechanism involved in the onset of arteriosclerosis in obesity]. Nihon Naika Gakkai Zasshi 1998 0.75
127 [Studies on an ultrasonic diagnosis in ophthalmology. 3. An ultra-sound technique for the vitreous body of healthy and affected eyes]. Nihon Ganka Kiyo 1971 0.75
128 [Thyroid function test by GammaCoat T3 uptake kit (author's transl)]. Radioisotopes 1978 0.75
129 [Determination of thyroxine by T4-RIAPAC and Seralute T4-RIA kits (author's transl)]. Radioisotopes 1977 0.75
130 [A case of neurogenic bladder complicated by an acute rash syndrome (measles?)]. Hinyokika Kiyo 1988 0.75
131 Cycle length change during reciprocating tachycardia in patients with Wolff-Parkinson-White syndrome. J Electrocardiol 1985 0.75