Published in J Biol Chem on July 26, 1996
Crystal structures of myoglobin-ligand complexes at near-atomic resolution. Biophys J (1999) 3.55
Ligand migration pathway and protein dynamics in myoglobin: a time-resolved crystallographic study on L29W MbCO. Proc Natl Acad Sci U S A (2005) 1.69
Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10). Biophys J (1999) 1.29
Atomic level computational identification of ligand migration pathways between solvent and binding site in myoglobin. Proc Natl Acad Sci U S A (2008) 1.28
Influence of the heme pocket conformation on the structure and vibrations of the Fe-CO bond in myoglobin: a QM/MM density functional study. Biophys J (2001) 1.23
Mechanisms of nitrite bioactivation. Nitric Oxide (2013) 1.22
Structure and reactivity of hexacoordinate hemoglobins. Biophys Chem (2010) 1.18
Temperature-dependent studies of NO recombination to heme and heme proteins. J Am Chem Soc (2005) 1.13
The effect of ligand dynamics on heme electronic transition band III in myoglobin. Biophys J (2002) 1.11
Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin. Proc Natl Acad Sci U S A (2009) 1.10
Protein ligand migration mapped by nonequilibrium 2D-IR exchange spectroscopy. Proc Natl Acad Sci U S A (2007) 1.07
Water and ligand entry in myoglobin: assessing the speed and extent of heme pocket hydration after CO photodissociation. Proc Natl Acad Sci U S A (2006) 1.07
Investigations of vibrational coherence in the low-frequency region of ferric heme proteins. Biophys J (2007) 1.05
Human myoglobin recognition of oxygen: dynamics of the energy landscape. Proc Natl Acad Sci U S A (2004) 1.03
Evidence for dynamics in proteins as a mechanism for ligand dissociation. Nat Chem Biol (2012) 1.03
The apolar channel in Cerebratulus lacteus hemoglobin is the route for O2 entry and exit. J Biol Chem (2008) 1.01
Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron. Biochem J (2003) 0.98
CO rebinding to protoheme: investigations of the proximal and distal contributions to the geminate rebinding barrier. J Am Chem Soc (2005) 0.96
The distal pocket histidine residue in horse heart myoglobin directs the O-binding mode of nitrite to the heme iron. J Am Chem Soc (2009) 0.94
The structure of neuroglobin at high Xe and Kr pressure reveals partial conservation of globin internal cavities. Biophys J (2009) 0.94
Ultrafast dynamics of diatomic ligand binding to nitrophorin 4. J Am Chem Soc (2010) 0.93
Blocking the gate to ligand entry in human hemoglobin. J Biol Chem (2010) 0.92
Harmonic and anharmonic dynamics of Fe-CO and Fe-O(2) in heme models. Biophys J (2000) 0.91
Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene (2007) 0.90
Modulating distal cavities in the α and β subunits of human HbA reveals the primary ligand migration pathway. Biochemistry (2011) 0.89
Hemoglobin-mediated nitric oxide signaling. Free Radic Biol Med (2013) 0.88
The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1. Proteins (2010) 0.86
Reaction of variant sperm-whale myoglobins with hydrogen peroxide: the effects of mutating a histidine residue in the haem distal pocket. Biochem J (1997) 0.86
Dynamics of nitric oxide rebinding and escape in horseradish peroxidase. J Am Chem Soc (2006) 0.84
Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding. Biophys J (2001) 0.84
Direct detection of the oxygen rebound intermediates, ferryl Mb and NO2, in the reaction of metmyoglobin with peroxynitrite. J Am Chem Soc (2009) 0.84
An atomistic view on human hemoglobin carbon monoxide migration processes. Biophys J (2012) 0.84
Exploring the mechanisms of the reductase activity of neuroglobin by site-directed mutagenesis of the heme distal pocket. Biochemistry (2015) 0.83
Spectroscopic and mechanistic investigations of dehaloperoxidase B from Amphitrite ornata. Biochemistry (2010) 0.83
The pH dependence of heme pocket hydration and ligand rebinding kinetics in photodissociated carbonmonoxymyoglobin. J Biol Chem (2008) 0.82
Optical detection of disordered water within a protein cavity. J Am Chem Soc (2009) 0.82
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water. J Biol Chem (2008) 0.81
Internal water and microsecond dynamics in myoglobin. J Phys Chem B (2013) 0.81
Influence of histidine tag attachment on picosecond protein dynamics. Biochemistry (2011) 0.81
Parallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB. J Am Chem Soc (2012) 0.80
Role of the distal hydrogen-bonding network in regulating oxygen affinity in the truncated hemoglobin III from Campylobacter jejuni. Biochemistry (2011) 0.80
Kinetic spectroscopy of heme hydration and ligand binding in myoglobin and isolated hemoglobin chains: an optical window into heme pocket water dynamics. Phys Chem Chem Phys (2010) 0.79
Quantifying the importance of protein conformation on ligand migration in myoglobin. Biophys J (2012) 0.79
Influence of distal residue B10 on CO dynamics in myoglobin and neuroglobin. J Biol Phys (2008) 0.79
Binding and docking interactions of NO, CO and O₂in heme proteins as probed by density functional theory. Int J Mol Sci (2009) 0.79
Role of copper ion in regulating ligand binding in a myoglobin-based cytochrome C oxidase model. J Am Chem Soc (2010) 0.79
Multiple geminate ligand recombinations in human hemoglobin. Biophys J (2000) 0.79
A possible mechanism for redox control of human neuroglobin activity. J Chem Inf Model (2014) 0.78
Time-resolved flow-flash FT-IR difference spectroscopy: the kinetics of CO photodissociation from myoglobin revisited. Anal Bioanal Chem (2009) 0.77
Myoglobin mutants giving the largest geminate yield in CO rebinding in the nanosecond time domain. Biophys J (1998) 0.77
Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca. PLoS One (2012) 0.77
Proximal influences in two-on-two globins: effect of the Ala69Ser replacement on Synechocystis sp. PCC 6803 hemoglobin. Biochemistry (2006) 0.76
New function of aldoxime dehydratase: Redox catalysis and the formation of an expected product. PLoS One (2017) 0.75
Dynamic features of carboxy cytoglobin distal mutants investigated by molecular dynamics simulations. J Biol Inorg Chem (2016) 0.75
Carbon monoxide binding properties of domain-swapped dimeric myoglobin. J Biol Inorg Chem (2015) 0.75
The molecular structure of green fluorescent protein. Nat Biotechnol (1996) 9.63
Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc Natl Acad Sci U S A (1981) 5.56
Crystal structure of photolysed carbonmonoxy-myoglobin. Nature (1994) 3.78
Mechanism of NO-induced oxidation of myoglobin and hemoglobin. Biochemistry (1996) 3.36
Tropomyosin crystal structure and muscle regulation. J Mol Biol (1986) 2.65
Crystal structures of CO-, deoxy- and met-myoglobins at various pH values. J Mol Biol (1996) 2.58
High-resolution crystal structures of distal histidine mutants of sperm whale myoglobin. J Mol Biol (1993) 2.37
Structural determinants of the stretching frequency of CO bound to myoglobin. Biochemistry (1994) 2.18
Crystal structure and molecular interactions of tropomyosin. Nature (1979) 2.16
His64(E7)-->Tyr apomyoglobin as a reagent for measuring rates of hemin dissociation. J Biol Chem (1994) 1.87
Crystal structure of tropomyosin at 7 Angstroms resolution. Proteins (2000) 1.76
A global model of the protein-solvent interface. Biophys J (1994) 1.73
A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate. J Biol Chem (1992) 1.73
The closed conformation of a highly flexible protein: the structure of E. coli adenylate kinase with bound AMP and AMPPNP. Proteins (1994) 1.65
Motions of calmodulin characterized using both Bragg and diffuse X-ray scattering. Structure (1997) 1.63
A sampling problem in molecular dynamics simulations of macromolecules. Proc Natl Acad Sci U S A (1995) 1.59
Characterization of recombinant soybean leghemoglobin a and apolar distal histidine mutants. J Mol Biol (1997) 1.48
Troponin and its interactions with tropomyosin. An electron microscope study. J Mol Biol (1982) 1.48
Structure of co-crystals of tropomyosin and troponin. Nature (1987) 1.47
Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear metal center. Biochemistry (2001) 1.44
Structural and functional effects of apolar mutations of the distal valine in myoglobin. J Mol Biol (1995) 1.37
Paleosols and their relevance to Precambrian atmospheric composition J Geol (1989) 1.37
Crystal structure of a nonsymbiotic plant hemoglobin. Structure (2000) 1.36
Motions of tropomyosin. Crystal as metaphor. Biophys J (1980) 1.35
A model from electron microscopy for the molecular structure of fibrinogen and fibrin. Nature (1981) 1.29
Ligand pathways in myoglobin: a review of Trp cavity mutations. IUBMB Life (2007) 1.27
Effects of the location of distal histidine in the reaction of myoglobin with hydrogen peroxide. J Biol Chem (1999) 1.25
Structure of myoglobin-ethyl isocyanide. Histidine as a swinging door for ligand entry. J Mol Biol (1989) 1.15
Structure of tropomyosin at 9 angstroms resolution. J Mol Biol (1992) 1.13
Diffuse x-ray scattering from tropomyosin crystals. Biophys J (1992) 1.12
Motions of tropomyosin: characterization of anisotropic motions and coupled displacements in crystals. Biophys J (1986) 1.12
Nitric oxide myoglobin: crystal structure and analysis of ligand geometry. Proteins (1998) 1.11
Spikes and fimbriae: alpha-helical proteins form surface projections on microorganisms. Proc Natl Acad Sci U S A (1981) 1.10
The Klippel-Trenaunay syndrome: clinical and radiological aspects. Radiology (1978) 1.10
Characterizing global substates of myoglobin. Structure (1998) 1.08
Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin. Structure (1999) 1.07
Automatic identification of discrete substates in proteins: singular value decomposition analysis of time-averaged crystallographic refinements. Proteins (1995) 1.07
Cross-validation tests of time-averaged molecular dynamics refinements for determination of protein structures by X-ray crystallography. Acta Crystallogr D Biol Crystallogr (1994) 1.06
Waterproofing the heme pocket. Role of proximal amino acid side chains in preventing hemin loss from myoglobin. J Biol Chem (2000) 1.05
Analysis of diffuse scattering from yeast initiator tRNA crystals. Acta Crystallogr D Biol Crystallogr (1994) 1.04
Construction of an atomic model for tropomyosin and implications for interactions with actin. J Mol Biol (1986) 1.03
The structure of fibrinogen and fibrin: II. Architecture of the fibrin clot. Ann N Y Acad Sci (1983) 1.00
Solution and crystal structures of a sperm whale myoglobin triple mutant that mimics the sulfide-binding hemoglobin from Lucina pectinata. J Biol Chem (1998) 0.98
Phe-46(CD4) orients the distal histidine for hydrogen bonding to bound ligands in sperm whale myoglobin. Proteins (1995) 0.96
A cellular automaton model for the regulatory behavior of muscle thin filaments. Biophys J (1994) 0.95
The D-helix in myoglobin and in the beta subunit of hemoglobin is required for the retention of heme. Biochemistry (1995) 0.95
Crystallization and preliminary X-ray diffraction analysis of 11 S acetylcholinesterase. J Biol Chem (1988) 0.94
The 2.8-A resolution structure of the L-arabinose-binding protein from Escherichia coli. Polypeptide chain folding, domain similarity, and probable location of sugar-binding site. J Biol Chem (1977) 0.93
Letter: Crystallographic data of an L-arabinose-binding protein from Escherichia coli. J Mol Biol (1974) 0.92
How the CO in myoglobin acquired its bend: lessons in interpretation of crystallographic data. Acta Crystallogr D Biol Crystallogr (2001) 0.92
Analysis of diffuse scattering and relation to molecular motion. Methods Enzymol (1997) 0.91
High resolution crystal structures of the deoxy, oxy, and aquomet forms of cobalt myoglobin. J Biol Chem (1996) 0.90
The structure of fibrinogen and fibrin: I. Electron microscopy and X-ray crystallography of fibrinogen. Ann N Y Acad Sci (1983) 0.90
Nitric oxide recombination to double mutants of myoglobin: role of ligand diffusion in a fluctuating heme pocket. Biochemistry (1994) 0.90
Protein structure determination using a database of interatomic distance probabilities. Protein Sci (1999) 0.89
Study of global motions in proteins by weighted masses molecular dynamics: adenylate kinase as a test case. Proteins (1996) 0.88
A double mutant of sperm whale myoglobin mimics the structure and function of elephant myoglobin. J Biol Chem (1995) 0.88
Diffraction methods for biological macromolecules. Crystallization in capillary tubes. Methods Enzymol (1985) 0.86
Structure of L-arabinose-binding protein from Escherichia coli at 5 A resolution and preliminary results at 3.5 A. Proc Natl Acad Sci U S A (1976) 0.85
Conformational variation of calcium-bound troponin C. Proteins (1999) 0.83
Stabilization of myoglobin by multiple alanine substitutions in helical positions. Protein Sci (1994) 0.82
Assignment of the nucleotide binding sites and the mechanism of substrate inhibition of Escherichia coli adenylate kinase. Proteins (1991) 0.79
Coiled-coil packing in spermine-induced tropomyosin crystals. A comparative study of three forms. J Mol Biol (1994) 0.79
Crystallization and preliminary X-ray analysis of Escherichia coli adenylate kinase. J Mol Biol (1988) 0.78
Protein-assisted pericyclic reactions: an alternate hypothesis for the action of quantal receptors. Biophys J (1999) 0.78
Structural studies of tropomyosin by cryoelectron microscopy and x-ray diffraction. Biophys J (1991) 0.77
Structure of an anti-HIV monoclonal Fab antibody fragment specific to a gp120 C-4 region peptide. Proteins (2001) 0.76
Affinity and structure of complexes of tropomyosin and caldesmon domains. Biophys J (1996) 0.75
Biomedical informatics training at the University of Wisconsin-Madison. Yearb Med Inform (2007) 0.75
Protein switches in muscle contraction. Prog Clin Biol Res (1980) 0.75
A fast Newton method for entropy maximization in statistical phase estimation. Acta Crystallogr A (2001) 0.75
Preliminary electron crystallographic analysis of ice-embedded tropomyosin crystals. J Struct Biol (1993) 0.75
Ultrasonic evaluation of the scrotum. Urol Radiol (1981) 0.75
Crystallization and preliminary x-ray investigation of the regulatory subunit of cAMP-dependent protein kinase. J Biol Chem (1985) 0.75
Visualization of dynamic simulations of muscle thin filaments. J Mol Graph (1995) 0.75