Published in J Biol Chem on July 25, 1979
Hypothesis about the function of membrane-buried proline residues in transport proteins. Proc Natl Acad Sci U S A (1986) 2.90
Non-random distribution of amino acids in the transmembrane segments of human type I single span membrane proteins. J Mol Biol (1993) 2.70
Metabolic gene expression in fetal and failing human heart. Circulation (2001) 2.59
Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment. Proc Natl Acad Sci U S A (1996) 1.67
Proline residues in transmembrane helices: structural or dynamic role? Biochemistry (1991) 1.66
Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle. Acta Physiol Scand (2000) 1.63
Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte. Obes Rev (2007) 1.57
A measure of helical propensity for amino acids in membrane environments. Nat Struct Biol (1994) 1.52
Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers. J Am Chem Soc (1970) 1.45
Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy. J Mol Cell Cardiol (1999) 1.38
Discriminating the relation between relations: the role of entropy in abstract conceptualization by baboons (Papio papio) and humans (Homo sapiens). J Exp Psychol Anim Behav Process (2001) 1.37
Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J Mol Cell Cardiol (2000) 1.36
Depressive symptomatology in persons with spinal cord injury who reside in the community. Arch Phys Med Rehabil (1993) 1.29
Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency. Proc Natl Acad Sci U S A (2008) 1.29
Time-of-day-dependent dietary fat consumption influences multiple cardiometabolic syndrome parameters in mice. Int J Obes (Lond) (2010) 1.28
Relationship of life satisfaction to impairment, disability, and handicap among persons with spinal cord injury living in the community. Arch Phys Med Rehabil (1992) 1.27
Uncoupling hydrophobicity and helicity in transmembrane segments. Alpha-helical propensities of the amino acids in non-polar environments. J Biol Chem (1998) 1.24
Guidelines for membrane protein engineering derived from de novo designed model peptides. Biopolymers (1998) 1.20
Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. Diabetes (2000) 1.18
Glycine and beta-branched residues support and modulate peptide helicity in membrane environments. FEBS Lett (1992) 1.13
Ionophore A23187. Solution conformations of the calcium complex and free acid deduced from proton and carbon-13 nuclear magnetic resonance studies. Biochemistry (1976) 1.12
Interhelical hydrogen bonds in the CFTR membrane domain. Nat Struct Biol (2001) 1.12
Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles. Proc Natl Acad Sci U S A (1984) 1.11
Anionic phospholipids modulate peptide insertion into membranes. Biochemistry (1997) 1.11
Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR. Am J Physiol Endocrinol Metab (2001) 1.10
Structure and dynamics of bacteriophage IKe major coat protein in MPG micelles by solution NMR. Biochemistry (1996) 1.08
Retention of native-like oligomerization states in transmembrane segment peptides: application to the Escherichia coli aspartate receptor. Biochemistry (2001) 1.08
Antibodies to colony-stimulating factors block Lewis lung carcinoma cell stimulation of immune-suppressive bone marrow cells. Cancer Immunol Immunother (1991) 1.07
Amino acid composition of the membrane and aqueous domains of integral membrane proteins. Arch Biochem Biophys (1986) 1.06
Folding proteins into membranes. Nat Struct Biol (1996) 1.06
Bromo-A23187: a nonfluorescent calcium ionophore for use with fluorescent probes. Anal Biochem (1985) 1.05
Stimulation of splenic T-lymphocyte function by endogenous serotonin and by low-dose exogenous serotonin. Immunology (1993) 1.05
Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart. Biochem Biophys Res Commun (2001) 1.04
Characterization of the adenovirus 2 virion protein, mu. Virology (1989) 1.04
Peptides in membranes: lipid-induced secondary structure of substance P. Biopolymers (1987) 1.03
Regulation of murine T-lymphocyte function by spleen cell-derived and exogenous serotonin. Immunopharmacol Immunotoxicol (1992) 1.02
Packing of coat protein amphipathic and transmembrane helices in filamentous bacteriophage M13: role of small residues in protein oligomerization. J Mol Biol (1995) 1.02
Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice. Int J Obes (Lond) (2012) 1.01
Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. J Mol Biol (1994) 1.00
The role of cell-specific circadian clocks in metabolism and disease. Obes Rev (2009) 0.98
Minimum energy conformations of proline-containing helices. Biopolymers (1992) 0.98
Same-different conceptualization by baboons (Papio papio): the role of entropy. J Comp Psychol (2001) 0.97
Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins. Biochemistry (1981) 0.95
Cyclic peptides. IX. Conformations of a synthetic ion-binding cyclic peptide, cyclo-(pro-gly)3, from circular dichroism and 1H and 13C nuclear magnetic resonance. J Am Chem Soc (1974) 0.95
Influence of ether linkage on the lamellar to hexagonal phase transition of ethanolamine phospholipids. Biochemistry (1981) 0.94
Cyclic peptides. II. Solution conformations of cyclo(ProlyLserylglycylprolylserylglycyl) from nuclear magnetic resonance. J Am Chem Soc (1972) 0.93
Evidence for a folded conformation of methionine- and leucine-enkephalin in a membrane environment. J Biol Chem (1984) 0.91
Creatine uptake in isolated soleus muscle: kinetics and dependence on sodium, but not on insulin. Acta Physiol Scand (1999) 0.91
Tumor-derived cytokines induce bone marrow suppressor cells that mediate immunosuppression through transforming growth factor beta. Cancer Immunol Immunother (1992) 0.91
Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide. Biochem Biophys Res Commun (1998) 0.90
Radiation dose and second breast cancer. Br J Cancer (1985) 0.90
Peptide environment specifies conformation. Helicity of hydrophobic segments compared in aqueous, organic, and membrane environments. J Biol Chem (1993) 0.89
Threshold hydrophobicity dictates helical conformations of peptides in membrane environments. Biopolymers (1996) 0.89
Cyclic peptides. 3. Solution conformations of cyclo(serylprolylglycylserylprolylglycyl) from nuclear magnetic resonance. J Am Chem Soc (1972) 0.88
Myelopoiesis-associated suppressor-cell activity in mice with Lewis lung carcinoma tumors: interferon-gamma plus tumor necrosis factor-alpha synergistically reduce suppressor cell activity. Int J Cancer (1990) 0.88
Peptide mimics of the M13 coat protein transmembrane segment. Retention of helix-helix interaction motifs. J Biol Chem (2000) 0.87
Assistive technology and the newly disabled adult: adaptation to wheelchair use. Am J Occup Ther (1993) 0.86
Cyclic peptides. I. Cyclo(tri-l-prolyl) and derivatives. Synthesis and molecular conformation from nuclear magnetic resonance. J Am Chem Soc (1971) 0.85
Influence of glycine residues on peptide conformation in membrane environments. Int J Pept Protein Res (1993) 0.85
Effects of number of items on the baboon's discrimination of same from different visual displays. Anim Cogn (2001) 0.85
Display variability and spatial organization as contributors to the pigeon's discrimination of complex visual stimuli. J Exp Psychol Anim Behav Process (2000) 0.85
Seeing things from a different angle: the pigeon's recognition of single geons rotated in depth. J Exp Psychol Anim Behav Process (2000) 0.85
Synthesis and characterization of halogenated derivatives of the ionophore A23187: enhanced calcium ion transport specificity by the 4-bromo derivative. Biochemistry (1981) 0.85
Empirical equations for the representation of depth dose data for computerized treatment planning. Br J Radiol (1975) 0.85
Conformational states of mutant M13 coat proteins are regulated by transmembrane residues. J Biol Chem (1993) 0.85
Cyclic peptides. 17. Metal and amino acid complexes of cyclo(pro-gly)4 and analogues studied by nuclear magnetic resonance and circular dichroism. J Am Chem Soc (1977) 0.84
Calcium transport by ionophorous peptides in dog and human lymphocytes detected by quin-2 fluorescence. Biochem Biophys Res Commun (1986) 0.84
Sexual activities, concerns and interests of men with spinal cord injury. Am J Phys Med Rehabil (1992) 0.84
Evidence for similar function of transmembrane segments in receptor and membrane-anchored proteins. Biopolymers (1988) 0.84
Granulocyte-macrophage colony-stimulating factor stimulates the metastatic properties of Lewis lung carcinoma cells through a protein kinase A signal-transduction pathway. Int J Cancer (1993) 0.84
Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides. J Pept Res (2005) 0.84
The structure and function of central nervous system myelin. Crit Rev Clin Lab Sci (1993) 0.84
Gas chromatographic/mass spectrometric analysis of methylphenidate (ritalin) in serum. Clin Biochem (1980) 0.84
Synthetic cation transport peptides: calcium transport across phospholipid membranes. Biochemistry (1980) 0.83
13C NMR relaxation studies of complexes between cyclo(L-Pro-Gly)3 and amino acids. Conformational aspects of stepwise binding. J Am Chem Soc (1977) 0.83
Combining hydrophobicity and helicity: a novel approach to membrane protein structure prediction. Bioorg Med Chem (1999) 0.82
Role of aromatic residues at the lipid-water interface in micelle-bound bacteriophage M13 major coat protein. Biochemistry (2000) 0.81
Solubilization of hydrophobic peptides by reversible cysteine PEGylation. Biochem Biophys Res Commun (1998) 0.81
An irregularity in the transmembrane domain helix correlates with the rate of insulin receptor internalization. Biochemistry (1994) 0.81
Effect of prostaglandin E2-producing nonmetastatic Lewis lung carcinoma cells on the migration of prostaglandin E2-responsive metastatic Lewis lung carcinoma cells. Cancer Res (1987) 0.81
The vesicular transport protein Cgp1p/Vps54p/Tcs3p/Luv1p is required for the integrity of the actin cytoskeleton. Mol Genet Genomics (2002) 0.81
A measure of helical propensity for amino acids in membrane environments. Nat Struct Biol (1994) 0.81
Binding of myelin basic protein to phospholipid micelles. J Biol Chem (1982) 0.81
Conformations of neurotensin in solution and in membrane environments studied by 2-D NMR spectroscopy. Int J Pept Protein Res (1991) 0.81
Stimulation of immune-suppressive bone marrow cells by colony-stimulating factors. Exp Hematol (1990) 0.81
NMR investigation of the charge isomers of bovine myelin basic protein. Arch Biochem Biophys (1984) 0.80
Letter: Amino acid-cyclic peptide complexes. J Am Chem Soc (1974) 0.80
Manipulation of peptide conformations by fine-tuning of the environment and/or the primary sequence. Biopolymers (1995) 0.80
Changes in the dose-profile of a 10 MV x-ray beam within and beyond low density material. Med Phys (1982) 0.79
Cystic fibrosis transmembrane conductance regulator: expression and helicity of a double membrane-spanning segment. FEBS Lett (1998) 0.79
Viable transmembrane region mutants of bacteriophage M13 coat protein prepared by site-directed mutagenesis. Biochem Biophys Res Commun (1991) 0.79
Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein. J Biol Chem (1984) 0.79
Activation of the protein kinase a signal transduction pathway by granulocyte-macrophage colony-stimulating factor or by genetic manipulation reduces cytoskeletal organization in Lewis lung carcinoma variants. Int J Cancer (1994) 0.79
Evidence for beta-turn analogs in proline peptides in the solid state. An infrared study. Macromolecules (1974) 0.78
Dependence of extracellular chitinase activity of Serratia marcescens QMB1466 on continuous culture dilution rate. Can J Microbiol (1981) 0.78
Stimulation of the metastatic properties of Lewis-lung-carcinoma cells by autologous granulocyte-macrophage colony-stimulating factor. Int J Cancer (1992) 0.78
Differential induction of hematopoiesis and immune suppressor cells in the bone marrow versus in the spleen by Lewis lung carcinoma variants. J Leukoc Biol (1989) 0.78