Published in Mol Cell Biol on August 01, 1996
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol (2001) 8.95
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest (2000) 7.06
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A (1999) 4.91
Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol Cell Biol (2004) 3.12
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Mol Cell Biol (2005) 2.93
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc Natl Acad Sci U S A (2006) 2.71
The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol (1997) 2.64
RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. J Clin Invest (1999) 2.51
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. J Clin Invest (1998) 2.42
Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth. J Clin Invest (2000) 2.12
Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart. J Clin Invest (2007) 1.88
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A (1997) 1.55
Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth. Heart Fail Rev (2002) 1.36
Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation. Proc Natl Acad Sci U S A (1997) 1.29
Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression. Mol Cell Endocrinol (2006) 1.04
Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha. Mol Cell Biol (2009) 0.93
Isolation of pig mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene promoter: characterization of a peroxisome proliferator-responsive element. Biochem J (1999) 0.88
Structural characterization of the mouse long-chain acyl-CoA dehydrogenase gene and 5' regulatory region. Mamm Genome (1998) 0.87
Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart. Biochim Biophys Acta (2006) 0.84
Metabolic reserve of the heart: the forgotten link between contraction and coronary flow. Prog Cardiovasc Dis (2008) 0.83
Effects of PPARα/PGC-1α on the energy metabolism remodeling and apoptosis in the doxorubicin induced mice cardiomyocytes in vitro. Int J Clin Exp Pathol (2015) 0.77
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature (1994) 7.86
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev (1994) 3.54
COUP transcription factor is a member of the steroid receptor superfamily. Nature (1989) 3.21
Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell (1994) 3.16
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A (1994) 3.00
Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science (1991) 2.70
Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res (1994) 2.58
The tissue-specific expression and developmental regulation of two nuclear genes encoding rat mitochondrial proteins. Medium chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase. J Biol Chem (1989) 1.91
Gel electrophoresis assays for DNA-protein interactions. Biotechniques (1989) 1.86
The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol (1994) 1.70
Beta oxidation of fatty acids. Biochim Biophys Acta (1991) 1.62
Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element. J Biol Chem (1993) 1.50
Developmental, nutritional, and hormonal regulation of tissue-specific expression of the genes encoding various acyl-CoA dehydrogenases and alpha-subunit of electron transfer flavoprotein in rat. J Biol Chem (1993) 1.44
A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene. J Biol Chem (1995) 1.41
Carnitine palmitolyltransferase activity and fatty acid oxidation by livers from fetal and neonatal rats. Can J Biochem (1970) 1.39
A pleiotropic element in the medium-chain acyl coenzyme A dehydrogenase gene promoter mediates transcriptional regulation by multiple nuclear receptor transcription factors and defines novel receptor-DNA binding motifs. Mol Cell Biol (1994) 1.36
Sudden child death and 'healthy' affected family members with medium-chain acyl-coenzyme A dehydrogenase deficiency. Pediatrics (1986) 1.33
EFIA/YB-1 is a component of cardiac HF-1A binding activity and positively regulates transcription of the myosin light-chain 2v gene. Mol Cell Biol (1995) 1.17
Identification of a novel retinoid-responsive element in the promoter region of the medium chain acyl-coenzyme A dehydrogenase gene. J Biol Chem (1992) 1.16
A novel, tissue-restricted zinc finger protein (HF-1b) binds to the cardiac regulatory element (HF-1b/MEF-2) in the rat myosin light-chain 2 gene. Mol Cell Biol (1993) 1.14
The human medium chain Acyl-CoA dehydrogenase gene promoter consists of a complex arrangement of nuclear receptor response elements and Sp1 binding sites. J Biol Chem (1995) 1.13
Structural organization and regulatory regions of the human medium-chain acyl-CoA dehydrogenase gene. Biochemistry (1992) 1.11
Characterization of the novel brown adipocyte cell line HIB 1B. Adrenergic pathways involved in regulation of uncoupling protein gene expression. J Cell Sci (1994) 1.11
Changes in mitochondrial respiratory chain proteins during perinatal development. Evidence of the importance of environmental oxygen tension. Biochim Biophys Acta (1971) 1.10
An M-CAT binding factor and an RSRF-related A-rich binding factor positively regulate expression of the alpha-cardiac myosin heavy-chain gene in vivo. Mol Cell Biol (1994) 1.07
Fatty acid utilization during development of the rat. Biochem J (1970) 1.04
Functional interactions of peroxisome proliferator-activated receptor, retinoid-X receptor, and Sp1 in the transcriptional regulation of the acyl-coenzyme-A oxidase promoter. Mol Endocrinol (1995) 1.00
Tissue specific and developmental expression of rat long-and medium-chain acyl-CoA dehydrogenases. Biochim Biophys Acta (1993) 0.98
Molecular cloning and characterization of the mouse medium-chain acyl-CoA dehydrogenase cDNA. Genomics (1994) 0.94
Cellular energy metabolism during fetal development. IV. Fatty acid activation, acyl transfer and fatty acid oxidation during development of the chick and rat. Dev Biol (1972) 0.93
Acyl-CoA dehydrogenase enzymes during early postnatal development in the rat. Biol Neonate (1989) 0.88
Developmental changes of myocardial metabolism. II. Myocardial metabolism of fatty acids in the early postnatal period in dogs. Biol Neonat (1968) 0.85
Obesity. Brown fat and yellow mice. Nature (1994) 0.79
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest (2000) 7.06
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol (2000) 6.29
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A (1999) 4.91
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A (2001) 3.96
Prevalence of psychiatric disorders in youths across five sectors of care. J Am Acad Child Adolesc Psychiatry (2001) 3.59
Prevalence of adolescent substance use disorders across five sectors of care. J Am Acad Child Adolesc Psychiatry (2001) 3.39
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A (1994) 3.00
Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation (1996) 2.87
Nucleotide sequence of medium-chain acyl-CoA dehydrogenase mRNA and its expression in enzyme-deficient human tissue. Proc Natl Acad Sci U S A (1987) 2.55
Studies on the growth of Thiobacillus ferrooxidans. I. Use of membrane filters and ferrous iron agar to determine viable numbers, and comparison with 14 CO 2 -fixation and iron oxidation as measures of growth. Arch Mikrobiol (1973) 2.55
Detection of cell-dependent cytotoxic antibody to cells infected with herpes simplex virus. Nature (1974) 2.55
RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. J Clin Invest (1999) 2.51
Antibody-dependent cell-mediated cytotoxicity to target cells infected with type 1 and type 2 herpes simplex virus. J Immunol (1976) 2.49
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. J Clin Invest (1998) 2.42
Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha. J Biol Chem (1998) 2.33
Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation. Proc Natl Acad Sci U S A (1998) 2.22
PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med (2000) 2.19
Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth. J Clin Invest (2000) 2.12
22q13 deletion syndrome. Am J Med Genet (2001) 1.94
Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol (2001) 1.94
Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse. Hum Mol Genet (2001) 1.93
Effect of physician recommendation and patient adherence on rates of colorectal cancer testing. Cancer Detect Prev (2004) 1.90
Biochemistry of the chemolithotrophic oxidation of inorganic sulphur. Philos Trans R Soc Lond B Biol Sci (1982) 1.83
PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice. J Clin Invest (2001) 1.82
A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation. J Biol Chem (1997) 1.65
Autotrophy: concepts of lithotrophic bacteria and their organic metabolism. Annu Rev Microbiol (1971) 1.64
Mechanisms of ampicillin resistance in Haemophilus influenzae type B. Antimicrob Agents Chemother (1976) 1.56
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A (1997) 1.55
p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response. J Biol Chem (2001) 1.53
Oxidation kinetics and chemostat growth kinetics of Thiobacillus ferrooxidans on tetrathionate and thiosulfate. J Bacteriol (1978) 1.51
Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element. J Biol Chem (1993) 1.50
Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation. J Clin Invest (1998) 1.50
Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle. Am J Physiol (1996) 1.45
Methylosulfonomonas methylovora gen. nov., sp. nov., and Marinosulfonomonas methylotropha gen. nov., sp. nov.: novel methylotrophs able to grow on methanesulfonic acid. Arch Microbiol (1997) 1.43
The role of acculturation in the substance abuse behavior of African-American and Latino adolescents: advances, issues, and recommendations. J Psychoactive Drugs (2000) 1.43
[Epidemiology of the osteoporotic fracture of the hip in the province of Palencia]. Rev Clin Esp (1997) 1.43
Cobalamin deficiency associated with methylmalonic acidemia in a cat. J Am Vet Med Assoc (1992) 1.40
Information process in the lateral semicircular canals. Dokl Biol Sci (2011) 1.39
Structural effects in solvolytic reactions; carbon-13 NMR studies of carbocations: Effect of increasing electron demand on the carbon-13 NMR shifts in substituted tert-cumyl and 1-aryl-1-cyclopentyl carbocations-correlation of the data by a new set of substituent constants, sigma. Proc Natl Acad Sci U S A (1980) 1.39
A pleiotropic element in the medium-chain acyl coenzyme A dehydrogenase gene promoter mediates transcriptional regulation by multiple nuclear receptor transcription factors and defines novel receptor-DNA binding motifs. Mol Cell Biol (1994) 1.36
Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation. J Biol Chem (2001) 1.34
Biology of Thiobacillus ferrooxidans in relation to the microbiological leaching of sulphide ores. Z Allg Mikrobiol (1972) 1.32
Cognitive and academic late effects among children previously treated for acute lymphocytic leukemia receiving chemotherapy as CNS prophylaxis. J Pediatr Psychol (1998) 1.32
Effects of substance abuse on housing stability of homeless mentally Ill persons in supported housing. Psychiatr Serv (1996) 1.29
Fatty acid utilization in the hypertrophied and failing heart: molecular regulatory mechanisms. Am J Med Sci (1999) 1.28
The complete nucleotide sequence of canine brain B creatine kinase mRNA: homology in the coding and 3' noncoding regions among species. Biochem Biophys Res Commun (1986) 1.26
The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism. Prostaglandins Leukot Essent Fatty Acids (2000) 1.26
Studies on the growth of Thiobacillus ferrooxidans. V. Factors affecting growth in liquid culture and development of colonies on solid media containing inorganic sulphur compounds. Arch Microbiol (1974) 1.26
The incorporation of acetate by the chemoautotroph Thiobacillus neapolitanus strain C. Arch Mikrobiol (1967) 1.22
A re-evaluation of the taxonomy of Paracoccus denitrificans and a proposal for the combination Paracoccus pantotrophus comb. nov. Int J Syst Bacteriol (1999) 1.19
Feline sphingolipidosis resembling Niemann-Pick disease type C. Acta Neuropathol (1990) 1.18
Identification of a novel retinoid-responsive element in the promoter region of the medium chain acyl-coenzyme A dehydrogenase gene. J Biol Chem (1992) 1.16
Reduced nicotinamide adenine dinucleotide oxidation by Thiobacillus neapolitanus and Thiobacillus strain C. J Bacteriol (1968) 1.16
Housing outcomes for homeless adults with mental illness: results from the second-round McKinney program. Psychiatr Serv (1997) 1.16
The energy substrate switch during development of heart failure: gene regulatory mechanisms (Review). Int J Mol Med (1998) 1.14
The human medium chain Acyl-CoA dehydrogenase gene promoter consists of a complex arrangement of nuclear receptor response elements and Sp1 binding sites. J Biol Chem (1995) 1.13
Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts. Lab Invest (1991) 1.12
Structural organization and regulatory regions of the human medium-chain acyl-CoA dehydrogenase gene. Biochemistry (1992) 1.11
Circadian function in patients with advanced non-small-cell lung cancer. Br J Cancer (2005) 1.09
Sudden cardiac death in hypertrophic cardiomyopathy. Variability in phenotypic expression of beta-myosin heavy chain mutations. Eur Heart J (1995) 1.08
Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene. Hum Mutat (1992) 1.07
Antibody-dependent cellular cytotoxicity to target cells infected with herpes simplex viruses: functional adequacy in the neonate. Pediatrics (1977) 1.07
Human neonatal and maternal monocyte-macrophage and lymphocyte-mediated antibody-dependent cytotoxicity to cells infected with herpes simplex. J Pediatr (1978) 1.06
Identification and sequence analysis of the soxB gene essential for sulfur oxidation of Paracoccus denitrificans GB17. J Bacteriol (1994) 1.06
Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training. Am J Physiol Endocrinol Metab (2000) 1.05
Inhalation of high concentrations of low toxicity dusts in rats results in impaired pulmonary clearance mechanisms and persistent inflammation. Toxicol Appl Pharmacol (1997) 1.04
A novel pink-pigmented facultative methylotroph, Methylobacterium thiocyanatum sp. nov., capable of growth on thiocyanate or cyanate as sole nitrogen sources. Arch Microbiol (1998) 1.03
Influence of amino acids and organic antimetabolites on growth and biosynthesis of the chemoautotroph Thiobacillus neapolitanus strain C. Arch Mikrobiol (1967) 1.03
Circadian dynamics of tumor necrosis factor alpha (cachectin) lethality. J Exp Med (1994) 1.00
[35S]thiosulphate oxidation by Thiobacillus strain C. Biochem J (1966) 0.98
Transcriptional control of cardiac fuel metabolism and mitochondrial function. Cold Spring Harb Symp Quant Biol (2011) 0.98
Problems of the autotrophic micro-organisms. Sci Prog (1967) 0.98
Survival and dependence on home parenteral nutrition: experience over a 25-year period in a UK referral centre. Aliment Pharmacol Ther (2006) 0.98
Assimilation and toxicity of some exogenous C1 compounds, alcohols, sugars and acetate in the methane-oxidizing bacterium Methylococcus capsulatus. J Gen Microbiol (1973) 0.97
Regulation of chemoautotrophic metabolism. I. Toxicity of phenylalanine to thiobacilli. Arch Mikrobiol (1969) 0.96
Regulation of ATP synthase subunit e gene expression by hypoxia: cell differentiation stage-specific control. Am J Physiol (1997) 0.96
Insulin-like growth factor (IGF)-I and IGF-binding protein 3 during the first year in term and preterm infants. Pediatr Res (1995) 0.96
Regulatory networks controlling mitochondrial energy production in the developing, hypertrophied, and diabetic heart. Cold Spring Harb Symp Quant Biol (2002) 0.95
Crossroads for archaebacteria. Nature (1985) 0.95
CD20-positive infiltrates in renal allograft biopsies with acute cellular rejection are not associated with worse graft survival. Am J Transplant (2007) 0.95
Regulation of chemoautotrophic metabolism. 3. DAHP synthetase in Thiobacillus neapolitanus. Arch Mikrobiol (1969) 0.94
Childhood and adolescent onset conduct disorder: a test of the developmental taxonomy. J Abnorm Child Psychol (2001) 0.94
Molecular cloning and characterization of the mouse medium-chain acyl-CoA dehydrogenase cDNA. Genomics (1994) 0.94
Structure and chromosomal location of the mouse medium-chain acyl-CoA dehydrogenase-encoding gene and its promoter. Gene (1996) 0.93
Reduction of fensulfothion to fensulfothion sulfide by Klebsiella pneumoniae. Appl Environ Microbiol (1977) 0.93
Fluorescence polarization analysis, lipid composition, and Na+, K+-ATPase kinetics of synaptosomal membranes in feline GM1 and GM2 gangliosidosis. J Neurochem (1985) 0.93
Characterization of wild-type and an active site mutant of human medium chain acyl-CoA dehydrogenase after expression in Escherichia coli. J Biol Chem (1990) 0.93
Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme. Microbiology (1996) 0.91
GM2 gangliosidosis in a Japanese spaniel. Acta Neuropathol (1985) 0.91