Published in Exp Eye Res on May 01, 1996
Age-related macular degeneration--emerging pathogenetic and therapeutic concepts. Ann Med (2006) 2.99
Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex. Mol Aspects Med (2012) 2.37
'What controls aqueous humour outflow resistance?'. Exp Eye Res (2006) 2.35
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. Prog Retin Eye Res (2009) 1.80
Aging and vision. Vision Res (2010) 1.65
The oil spill in ageing Bruch membrane. Br J Ophthalmol (2011) 1.62
Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model. Am J Pathol (2002) 1.58
Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration. J Lipid Res (2009) 1.41
Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Retin Eye Res (2010) 1.39
Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Prog Retin Eye Res (2014) 1.17
Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch. Exp Eye Res (2007) 1.14
CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits. Aging (Albany NY) (2010) 1.04
Retinectomy for treatment of intractable glaucoma: long term results. Br J Ophthalmol (2003) 0.98
Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane. Invest Ophthalmol Vis Sci (2008) 0.97
The ins and outs of cholesterol in the vertebrate retina. J Lipid Res (2010) 0.97
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration. Elife (2016) 0.93
Insights into pathology of cuticular drusen from integrated confocal scanning laser ophthalmoscopy imaging and corresponding spectral domain optical coherence tomography. Graefes Arch Clin Exp Ophthalmol (2011) 0.89
Multiplex analysis of age-related protein and lipid modifications in human Bruch's membrane. FASEB J (2010) 0.89
An experimental study of the elastic properties of the human Bruch's membrane-choroid complex: relevance to ageing. Br J Ophthalmol (2006) 0.89
Analysis of retinal pigment epithelium integrin expression and adhesion to aged submacular human Bruch's membrane. Trans Am Ophthalmol Soc (2003) 0.88
Age-related macular degeneration and changes in the extracellular matrix. Med Sci Monit (2014) 0.88
Passage of low-density lipoproteins through Bruch's membrane and choroid. Exp Eye Res (2011) 0.85
Recent advances in the dark adaptation investigations. Int J Ophthalmol (2015) 0.85
Effects of particulates and lipids on the hydraulic conductivity of Matrigel. J Appl Physiol (1985) (2008) 0.85
Fundus autofluorescence and spectral-domain optical coherence tomography characteristics in a rapidly progressing form of geographic atrophy. Invest Ophthalmol Vis Sci (2011) 0.84
Scotopic microperimetry in the early diagnosis of age-related macular degeneration: preliminary study. Biomed Res Int (2014) 0.79
The role of CD36 receptor in the phagocytosis of oxidized lipids and AMD. Aging (Albany NY) (2010) 0.79
A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics. Comput Methods Biomech Biomed Engin (2015) 0.78
Chronologic versus biologic aging of the human choroid. ScientificWorldJournal (2013) 0.78
Intrinsic tissue fluorescence in an organotypic perfusion culture of the porcine ocular fundus exposed to blue light and free radicals. Graefes Arch Clin Exp Ophthalmol (2008) 0.77
Passive permeability and outward active transport of fluorescein across the blood-retinal barrier in early ARM. Br J Ophthalmol (2001) 0.77
Relationship of stokes radius to the rate of diffusion across Bruch's membrane. Invest Ophthalmol Vis Sci (2011) 0.76
Neuroprotective Effects of Low-Dose Statins in the Retinal Ultrastructure of Hypercholesterolemic Rabbits. PLoS One (2016) 0.75
The 2014 Bowman Lecture-Bowman's and Bruch's: a tale of two membranes during the laser revolution. Eye (Lond) (2015) 0.75
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med (1999) 20.31
Cerebral blood flow in dementia. Arch Neurol (1975) 9.24
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell (1990) 9.21
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature (1992) 8.47
A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. N Engl J Med (1998) 4.81
Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet (1974) 3.91
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell (1991) 3.75
Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases? Crit Care Med (2001) 3.65
A rat brain Na+ channel alpha subunit with novel gating properties. Neuron (1988) 3.48
Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms. J Med Genet (2003) 3.25
Expression and characterization of the cystic fibrosis transmembrane conductance regulator. Nature (1990) 3.09
Visual capacity in the hemianopic field following a restricted occipital ablation. Brain (1974) 2.92
First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/leucovorin. Ann Oncol (2002) 2.87
A new trichrome-blue stain for detection of microsporidial species in urine, stool, and nasopharyngeal specimens. J Clin Microbiol (1993) 2.77
Intravitreal triamcinolone for uveitic cystoid macular edema: an optical coherence tomography study. Ophthalmology (2001) 2.61
The mas oncogene encodes an angiotensin receptor. Nature (1988) 2.53
Strategies for consulting with the community: the cases of four large-scale genetic databases. Sci Eng Ethics (2004) 2.47
A comparison of effective thyroxine ratio and free thyroxine in serum. Clin Chim Acta (1973) 2.39
Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain. Neuron (1990) 2.38
Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. Am J Hum Genet (1998) 2.34
The reported training and experience of editors in chief of specialist clinical medical journals. JAMA (1998) 2.21
Diet in the epidemiology of postmenopausal breast cancer in the New York State Cohort. Am J Epidemiol (1992) 2.17
Retinal pigment epithelial detachments in the elderly. Trans Ophthalmol Soc U K (1986) 2.15
Drug and alcohol problems among individuals with severe mental illness in south London. Br J Psychiatry (1996) 2.09
Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography. Brain (1981) 2.08
The interpretation of optical coherence tomography images of the retina. Invest Ophthalmol Vis Sci (1999) 2.06
An intervention to reduce the sale of cigarettes to minors. N Y State J Med (1990) 2.03
Aging changes in Bruch's membrane. A histochemical and morphologic study. Ophthalmology (1990) 1.99
Role of axoplasmic transport in the pathophysiology of ischaemic disc swelling. Br J Ophthalmol (1980) 1.98
New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med (2001) 1.95
Risk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. Crit Care Med (1999) 1.94
Saccades in presymptomatic and early stages of Huntington disease. Neurology (2006) 1.92
Biochemical and molecular characterization of a novel starch synthase from potato tubers. Plant J (1995) 1.91
Cardiopulmonary resuscitation directives on admission to intensive-care unit: an international observational study. Lancet (2001) 1.90
Aetiology of Post-arsphenamine Jaundice. Br Med J (1944) 1.89
Diurnal variation in occurrence of strokes. Stroke (1977) 1.88
Multiple organ dysfunction: baseline and serial component scores. Crit Care Med (2001) 1.88
Photorefractive keratectomy: a technique for laser refractive surgery. J Cataract Refract Surg (1988) 1.88
Nutritional epidemiology of postmenopausal breast cancer in western New York. Am J Epidemiol (1991) 1.87
Regional blood flow in the normal cerebral hemisphere. J Neurol Neurosurg Psychiatry (1969) 1.84
Effect of haematocrit on cerebral blood-flow in man. Lancet (1977) 1.80
A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol (2001) 1.80
The clinical utility of invasive diagnostic techniques in the setting of ventilator-associated pneumonia. Canadian Critical Care Trials Group. Chest (1999) 1.80
Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes. Proc Natl Acad Sci U S A (1986) 1.79
Computer assisted tomography in orbital disease. Br J Ophthalmol (1974) 1.79
Cerebral blood-flow in polycythaemia. Lancet (1977) 1.79
Addressing the question of the effect of RBC storage on clinical outcomes: the Red Cell Storage Duration Study (RECESS) (Section 7). Transfus Apher Sci (2010) 1.78
Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis. Ophthalmology (2000) 1.75
Cardiac dysrhythmia and transient cerebral ischaemic attacks. Lancet (1973) 1.71
Trichomonas vaginalis and cervical cancer. A prospective study in China. Ann Epidemiol (1995) 1.71
Lactation and breast cancer. Evidence for a negative association in premenopausal women. Am J Epidemiol (1985) 1.69
Initial clinical experience using a diode laser in the treatment of retinal vascular disease. Eye (Lond) (1989) 1.66
The natural history of amaurosis fugax. Brain (1968) 1.65
Model for deriving the optical performance of the myopic eye corrected with an intracorneal ring. J Refract Surg (1996) 1.64
SAP90 binds and clusters kainate receptors causing incomplete desensitization. Neuron (1998) 1.63
The role of axoplasmic transport in the pathogenesis of retinal cotton-wool spots. Br J Ophthalmol (1977) 1.62
Age-related variation in the hydraulic conductivity of Bruch's membrane. Invest Ophthalmol Vis Sci (1995) 1.61
Clinical NMR imaging of the brain: 140 cases. AJR Am J Roentgenol (1982) 1.61
Hospital services for patients with acute stroke in the United Kingdom: the Stroke Association Survey of consultant opinion. Age Ageing (1995) 1.59
Blinding laser weapons. BMJ (1997) 1.59
A Canadian survey of transfusion practices in critically ill patients. Transfusion Requirements in Critical Care Investigators and the Canadian Critical Care Trials Group. Crit Care Med (1998) 1.58
Immunocytochemical differentiation of microtubules in the cytoskeleton of Giardia lamblia using monoclonal antibodies to alpha-tubulin and polyclonal antibodies to associated low molecular weight proteins. J Cell Sci (1986) 1.55
Refractive index of the human corneal epithelium and stroma. J Refract Surg (1995) 1.55
Do blue light filters confer protection against age-related macular degeneration? Prog Retin Eye Res (2004) 1.54
The spatial and temporal determinants of campylobacteriosis notifications in New Zealand, 2001-2007. Epidemiol Infect (2011) 1.54
Retinal and epiretinal glia--an immunohistochemical study. Br J Ophthalmol (1984) 1.54
Breast cancer after mantle irradiation for Hodgkin's disease: correlation of clinical, pathologic, and molecular features including loss of heterozygosity at BRCA1 and BRCA2. Int J Radiat Oncol Biol Phys (2001) 1.53
Computerized tomography (the EMI Scanner): a comparison with pneumoencephalography and ventriculography. J Neurol Neurosurg Psychiatry (1976) 1.53
Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet (1980) 1.51
A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol (2005) 1.50
The pathogenesis of edema in diabetic maculopathy. Semin Ophthalmol (1999) 1.50
Excimer laser photorefractive keratectomy. 18-month follow-up. Ophthalmology (1992) 1.49
The formation of autofluorescent granules in cultured human RPE. Invest Ophthalmol Vis Sci (1989) 1.48
Effect of haematocrit on carotid stenosis and cerebral infarction. Lancet (1981) 1.48
Implementation of a 4-y, high-fiber, high-fruit-and-vegetable, low-fat dietary intervention: results of dietary changes in the Polyp Prevention Trial. Am J Clin Nutr (2001) 1.46
The role of stress, social support and age in survival from breast cancer. J Psychosom Res (1983) 1.46
Ulcerative colitis complicated by renal cell carcinoma: a series of three patients. Gut (1996) 1.46
Substance misuse and risk of aggression and offending among the severely mentally ill. Br J Psychiatry (1998) 1.46
The impact of displayed awards on the credibility and retention of Web site information. Proc AMIA Symp (2000) 1.46
Raised serum CA125 level in leiomyoma and leiomyosarcoma of gastrointestinal origin. Br J Surg (1993) 1.45
Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. J Neurophysiol (1992) 1.44
A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci U S A (1996) 1.44
Excimer laser treatment of corneal surface pathology: a laboratory and clinical study. Br J Ophthalmol (1991) 1.43
Predictors of success and failure in pulmonary rehabilitation. Eur Respir J (2006) 1.43
Thermal and mechanical mechanisms in laser damage to the retina. Invest Ophthalmol (1970) 1.43
Iris clipping of a diode laser beam when performing retinal photocoagulation. Br J Ophthalmol (1991) 1.42
Histopathology of ruby and argon laser lesions in monkey and human retina. A comparative study. Br J Ophthalmol (1975) 1.42
A comparative histopathological study of argon and krypton laser irradiations of the human retina. Br J Ophthalmol (1979) 1.41
Markers of coagulation activation after hepatic resection for cancer: evidence of sustained upregulation of coagulation. Anaesth Intensive Care (2011) 1.40
Computer-assisted tomography (EMI scanner). Its place in investigation of suspected intracranial tumours. Lancet (1974) 1.39
Papillofoveal traction in macular hole formation: the role of optical coherence tomography. Arch Ophthalmol (2000) 1.38
Gauze-induced granuloma ("gauzoma"): an uncommon complication of gauze reinforcement of berry aneurysms. J Neurosurg (1990) 1.38
Sorsby's fundus dystrophy. A light and electron microscopic study. Ophthalmology (1989) 1.38
The reliability of dietary history from the distant past. Am J Epidemiol (1987) 1.38
Subcortical arteriosclerotic encephalopathy: a clinical and radiological investigation. J Neurol Neurosurg Psychiatry (1981) 1.36
Ageing changes in Bruch's membrane and their functional implications. Trans Ophthalmol Soc U K (1978) 1.35
Does transfusion practice affect mortality in critically ill patients? Transfusion Requirements in Critical Care (TRICC) Investigators and the Canadian Critical Care Trials Group. Am J Respir Crit Care Med (1997) 1.34
Pavlovian conditioning of rat mucosal mast cells to secrete rat mast cell protease II. Science (1989) 1.34
Firearm safety counseling in primary care pediatrics: a randomized, controlled trial. Pediatrics (2000) 1.33