Published in Genes Dev on August 15, 1996
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol (1999) 16.81
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell (2003) 5.45
Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nat Genet (2007) 4.59
Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci U S A (2001) 4.42
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol (1999) 4.32
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol (1997) 4.11
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci U S A (2002) 3.46
DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95
Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. Mol Cell Biol (1998) 2.93
RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis. Genetics (1997) 2.36
Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol (2002) 2.35
Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol Cell Biol (2001) 2.34
Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11. Genetics (1998) 2.32
Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol Cell Biol (2001) 2.32
Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31
Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31
RAD51-dependent break-induced replication in yeast. Mol Cell Biol (2004) 2.29
Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52. Mol Cell Biol (1998) 2.19
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99
The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A. EMBO J (1997) 1.80
Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae. Genetics (2002) 1.79
Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae. Genetics (2001) 1.78
Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities. Mol Cell Biol (2004) 1.78
The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response. Am J Hum Genet (1999) 1.73
RAD51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates. Mol Cell Biol (2000) 1.71
Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.71
The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing. Genetics (2001) 1.69
The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae. PLoS Genet (2006) 1.57
Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell (2008) 1.56
Specific pathways prevent duplication-mediated genome rearrangements. Nature (2009) 1.55
Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity. Proc Natl Acad Sci U S A (2001) 1.54
Homologous DNA recombination in vertebrate cells. Proc Natl Acad Sci U S A (2001) 1.52
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics (2002) 1.51
Role of the Saccharomyces cerevisiae Rad51 paralogs in sister chromatid recombination. Genetics (2008) 1.41
A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA. Genetics (1999) 1.37
A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52. Genetics (2002) 1.32
Repair of chromosome ends after telomere loss in Saccharomyces. Mol Biol Cell (2001) 1.30
The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination. Mol Cell Biol (1997) 1.29
Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases. Nucleic Acids Res (2007) 1.29
Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae. Genetics (2014) 1.27
A novel allele of RAD52 that causes severe DNA repair and recombination deficiencies only in the absence of RAD51 or RAD59. Genetics (1999) 1.26
Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae. Genetics (2002) 1.26
Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes Dev (2009) 1.25
Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break. Mol Cell Biol (2003) 1.24
Molecular dissection of interactions between Rad51 and members of the recombination-repair group. Mol Cell Biol (2001) 1.24
Rad51 protein controls Rad52-mediated DNA annealing. J Biol Chem (2008) 1.23
Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining. Genetics (1999) 1.21
Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA. Mol Cell Biol (1998) 1.21
A double-strand break repair component is essential for S phase completion in fission yeast cell cycling. Mol Biol Cell (1999) 1.17
Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations. Genetics (2001) 1.17
Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae. RNA (2000) 1.15
DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. Mol Cell Biol (2005) 1.14
A core activity associated with the N terminus of the yeast RAD52 protein is revealed by RAD51 overexpression suppression of C-terminal rad52 truncation alleles. Genetics (1999) 1.14
Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable. Genetics (2001) 1.11
A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements. PLoS Genet (2011) 1.11
The homologous recombination system of Ustilago maydis. Fungal Genet Biol (2008) 1.07
Multiple interactions among the components of the recombinational DNA repair system in Schizosaccharomyces pombe. Genetics (2001) 1.06
A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol (2004) 1.06
Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA. EMBO J (2002) 1.05
Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. Genetics (2002) 1.04
RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiae. DNA Repair (Amst) (2008) 1.04
Partial depletion of histone H4 increases homologous recombination-mediated genetic instability. Mol Cell Biol (2005) 1.04
Chromosomal translocations caused by either pol32-dependent or pol32-independent triparental break-induced replication. Mol Cell Biol (2009) 1.02
The involvement of cellular recombination and repair genes in RNA-mediated recombination in Saccharomyces cerevisiae. Genetics (1998) 1.00
RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks. Mol Cell Biol (2011) 0.99
Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination. Nucleic Acids Res (2002) 0.99
Rad52-independent accumulation of joint circular minichromosomes during S phase in Saccharomyces cerevisiae. Mol Cell Biol (2003) 0.98
Histone acetyltransferase 1 promotes homologous recombination in DNA repair by facilitating histone turnover. J Biol Chem (2013) 0.95
Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae. Genetics (2003) 0.94
Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation. PLoS One (2011) 0.94
Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants. Nucleic Acids Res (2009) 0.94
Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination. J Biol Chem (2011) 0.94
Interaction between Ustilago maydis REC2 and RAD51 genes in DNA repair and mitotic recombination. Genetics (1997) 0.93
Noncanonical views of homology-directed DNA repair. Genes Dev (2016) 0.92
The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae. Genetics (2003) 0.92
Biochemistry of eukaryotic homologous recombination. Top Curr Genet (2007) 0.91
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication. Nucleic Acids Res (2007) 0.91
Positive and negative roles of homologous recombination in the maintenance of genome stability in Saccharomyces cerevisiae. Genetics (2003) 0.91
Rad51-independent interchromosomal double-strand break repair by gene conversion requires Rad52 but not Rad55, Rad57, or Dmc1. Mol Cell Biol (2007) 0.90
Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res (2006) 0.90
Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae. PLoS One (2008) 0.90
A versatile scaffold contributes to damage survival via sumoylation and nuclease interactions. Cell Rep (2014) 0.89
A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of Rad52-L89F to interact with Rad59. Genetics (2004) 0.89
Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery. Nucleic Acids Res (2011) 0.89
UV but not X rays stimulate homologous recombination between sister chromatids and homologs in a Saccharomyces cerevisiae mec1 (ATR) hypomorphic mutant. Mutat Res (2008) 0.88
RAD51-independent inverted-repeat recombination by a strand-annealing mechanism. DNA Repair (Amst) (2011) 0.88
Mechanism of homologous recombination and implications for aging-related deletions in mitochondrial DNA. Microbiol Mol Biol Rev (2013) 0.87
Cells expressing murine RAD52 splice variants favor sister chromatid repair. Mol Cell Biol (2006) 0.86
A properly configured ring structure is critical for the function of the mitochondrial DNA recombination protein, Mgm101. J Biol Chem (2012) 0.85
RAD59 and RAD1 cooperate in translocation formation by single-strand annealing in Saccharomyces cerevisiae. Curr Genet (2009) 0.84
Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates. Genome Dyn Stab (2008) 0.83
Role of the homologous recombination genes RAD51 and RAD59 in the resistance of Candida albicans to UV light, radiomimetic and anti-tumor compounds and oxidizing agents. Fungal Genet Biol (2010) 0.82
Investigation of the stability of yeast rad52 mutant proteins uncovers post-translational and transcriptional regulation of Rad52p. Genetics (2003) 0.81
Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation. J Biol Chem (2009) 0.80
Assessment of the biological pathways targeted by isocyanate using N-succinimidyl N-methylcarbamate in budding yeast Saccharomyces cerevisiae. PLoS One (2014) 0.80
Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells. BMC Pharmacol (2004) 0.78
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol (1999) 4.32
Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol (1995) 2.96
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol (1997) 2.73
Multiple pathways for homologous recombination in Saccharomyces cerevisiae. Genetics (1995) 2.68
Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics (2001) 2.46
Use of a chromosomal inverted repeat to demonstrate that the RAD51 and RAD52 genes of Saccharomyces cerevisiae have different roles in mitotic recombination. Genetics (1994) 2.15
Intramolecular recombination of linear DNA catalyzed by the Escherichia coli RecE recombination system. J Mol Biol (1985) 1.85
Partial purification of an enzyme from Saccharomyces cerevisiae that cleaves Holliday junctions. Proc Natl Acad Sci U S A (1985) 1.76
RAD51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates. Mol Cell Biol (2000) 1.71
The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing. Genetics (2001) 1.69
Genetic recombination of homologous plasmids catalyzed by cell-free extracts of Saccharomyces cerevisiae. Cell (1983) 1.56
Aberrant double-strand break repair in rad51 mutants of Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.40
Mutation of the gene encoding protein kinase C 1 stimulates mitotic recombination in Saccharomyces cerevisiae. Mol Cell Biol (1994) 1.38
Transposon-encoded site-specific recombination: nature of the Tn3 DNA sequences which constitute the recombination site res. EMBO J (1983) 1.36
Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein. Genetics (1995) 1.28
A novel allele of RAD52 that causes severe DNA repair and recombination deficiencies only in the absence of RAD51 or RAD59. Genetics (1999) 1.26
Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae. Genetics (2000) 1.25
A 5'-3' exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology. Mol Cell Biol (1993) 1.16
Plasmid recombination intermediates generated in a Saccharomyces cerevisiae cell-free recombination system. Mol Cell Biol (1985) 1.02
Stimulation of meiotic recombination in yeast by an ARS element. Genetics (1993) 1.01
Recombination in yeast and the recombinant DNA technology. Genome (1989) 1.00
Crossed-stranded DNA structures for investigating the molecular dynamics of the Holliday junction. J Mol Biol (1993) 1.00
Mitotic recombination within the centromere of a yeast chromosome. Science (1988) 0.99
Genetic recombination catalyzed by cell-free extracts of Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1984) 0.90