Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break.

PubWeight™: 2.32‹?› | Rank: Top 2%

🔗 View Article (PMC 86809)

Published in Mol Cell Biol on March 01, 2001

Authors

L Signon1, A Malkova, M L Naylor, H Klein, J E Haber

Author Affiliations

1: Department of Biology and Rosenstiel Center, Brandeis University, Waltham, Massachusetts 02254-9110, USA.

Articles citing this

Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50

Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc Natl Acad Sci U S A (2002) 3.70

Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev (2005) 2.91

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J Exp Med (2002) 2.86

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Proc Natl Acad Sci U S A (2002) 2.50

Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol (2002) 2.35

Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31

RAD51-dependent break-induced replication in yeast. Mol Cell Biol (2004) 2.29

The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae. Genetics (2002) 2.01

Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability. Proc Natl Acad Sci U S A (2003) 1.96

RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol Cell Biol (2005) 1.94

Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1. Proc Natl Acad Sci U S A (2004) 1.87

Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. EMBO J (2002) 1.84

Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae. Genetics (2002) 1.79

Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities. Mol Cell Biol (2004) 1.78

Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements. Mol Cell Biol (2007) 1.75

The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing. Genetics (2001) 1.69

Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks. Mol Cell Biol (2003) 1.65

Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Mol Cell Biol (2006) 1.63

Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis. Plant Cell (2004) 1.43

Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J (2001) 1.41

Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity. PLoS Genet (2015) 1.41

Role of the Saccharomyces cerevisiae Rad51 paralogs in sister chromatid recombination. Genetics (2008) 1.41

Spontaneous chromosome loss in Saccharomyces cerevisiae is suppressed by DNA damage checkpoint functions. Genetics (2001) 1.38

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. Nat Struct Mol Biol (2011) 1.36

Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A (2006) 1.32

RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev (2001) 1.32

Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae. Genetics (2002) 1.26

Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends. PLoS Genet (2010) 1.25

Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break. Mol Cell Biol (2003) 1.24

Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype. Mol Cell Biol (2005) 1.24

Repairing a double-strand chromosome break by homologous recombination: revisiting Robin Holliday's model. Philos Trans R Soc Lond B Biol Sci (2004) 1.20

Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch. PLoS Genet (2010) 1.19

XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids. Mol Cell Biol (2009) 1.19

A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae. Genetics (2008) 1.18

Break-induced DNA replication. Cold Spring Harb Perspect Biol (2013) 1.17

Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: role of RAD1 and the RAD52 epistasis group genes. Nucleic Acids Res (2003) 1.17

Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth. Mol Cell (2010) 1.17

RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break ends. PLoS Genet (2009) 1.15

EXO1 plays a role in generating type I and type II survivors in budding yeast. Genetics (2004) 1.13

A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements. PLoS Genet (2011) 1.11

Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence. Nucleic Acids Res (2006) 1.10

A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol (2004) 1.06

Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. Genetics (2002) 1.04

Microhomology directs diverse DNA break repair pathways and chromosomal translocations. PLoS Genet (2012) 1.02

The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae. Mol Cell Biol (2003) 1.00

Mechanisms of Rad52-independent spontaneous and UV-induced mitotic recombination in Saccharomyces cerevisiae. Genetics (2008) 1.00

Retrosequence formation restructures the yeast genome. Genes Dev (2007) 1.00

Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication. DNA Repair (Amst) (2007) 0.99

Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination. Nucleic Acids Res (2002) 0.99

Chromosome rearrangements via template switching between diverged repeated sequences. Genes Dev (2014) 0.98

Different mating-type-regulated genes affect the DNA repair defects of Saccharomyces RAD51, RAD52 and RAD55 mutants. Genetics (2006) 0.98

Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines. Genes Chromosomes Cancer (2010) 0.98

Formation of large palindromic DNA by homologous recombination of short inverted repeat sequences in Saccharomyces cerevisiae. Genetics (2002) 0.97

Recombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae. J Cell Biol (2005) 0.97

Genetic instability of heterozygous, hybrid, natural wine yeasts. Appl Environ Microbiol (2004) 0.97

Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint. Mol Biol Cell (2008) 0.95

Genome instability in rad54 mutants of Saccharomyces cerevisiae. Nucleic Acids Res (2003) 0.95

Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae. Genetics (2003) 0.94

Noncanonical views of homology-directed DNA repair. Genes Dev (2016) 0.92

The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae. Genetics (2003) 0.92

Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication. Nucleic Acids Res (2007) 0.91

Positive and negative roles of homologous recombination in the maintenance of genome stability in Saccharomyces cerevisiae. Genetics (2003) 0.91

Rad51-independent interchromosomal double-strand break repair by gene conversion requires Rad52 but not Rad55, Rad57, or Dmc1. Mol Cell Biol (2007) 0.90

Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res (2006) 0.90

Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery. Nucleic Acids Res (2011) 0.89

Large inverted repeats in the vicinity of a single double-strand break strongly affect repair in yeast diploids lacking Rad51. Mutat Res (2008) 0.88

Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo. Nucleic Acids Res (2006) 0.87

Break-induced replication and genome stability. Biomolecules (2012) 0.87

Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells. Mol Cell Biol (2003) 0.86

Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition. Mol Cell Biol (2007) 0.85

Frequent Interchromosomal Template Switches during Gene Conversion in S. cerevisiae. Mol Cell (2014) 0.84

An mre11 mutation that promotes telomere recombination and an efficient bypass of senescence. Genetics (2010) 0.84

Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae. DNA Repair (Amst) (2010) 0.82

Investigation of the stability of yeast rad52 mutant proteins uncovers post-translational and transcriptional regulation of Rad52p. Genetics (2003) 0.81

Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway. PLoS One (2013) 0.79

Multiple pathways suppress non-allelic homologous recombination during meiosis in Saccharomyces cerevisiae. PLoS One (2013) 0.79

Differential genetic interactions between Sgs1, DNA-damage checkpoint components and DNA repair factors in the maintenance of chromosome stability. Genome Integr (2011) 0.78

Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is Not Dependent on the Shu Complex. PLoS One (2016) 0.76

Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae. PLoS Genet (2016) 0.75

The many facets of homologous recombination at telomeres. Microb Cell (2015) 0.75

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination. DNA Repair (Amst) (2016) 0.75

Articles cited by this

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Mammalian telomeres end in a large duplex loop. Cell (1999) 12.12

Extrachromosomal rDNA circles--a cause of aging in yeast. Cell (1997) 8.68

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell (1993) 6.89

Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell (1993) 6.83

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J (1990) 5.94

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08

One-step transformation of yeast in stationary phase. Curr Genet (1992) 5.03

SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics (1996) 4.62

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev (1997) 4.57

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49

DNA strand annealing is promoted by the yeast Rad52 protein. Proc Natl Acad Sci U S A (1996) 4.42

Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics (1996) 4.33

Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol Mol Biol Rev (1997) 3.90

CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell (1997) 3.83

A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae. Genes Dev (1996) 3.81

Evidence that spontaneous mitotic recombination occurs at the two-strand stage. Proc Natl Acad Sci U S A (1978) 3.81

Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc Natl Acad Sci U S A (1995) 3.79

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1999) 3.79

Gene replacement with linear DNA fragments in wild-type Escherichia coli: enhancement by Chi sites. Genetics (1997) 3.62

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Unusual DNA sequences associated with the ends of yeast chromosomes. Nature (1984) 3.54

Collapse and repair of replication forks in Escherichia coli. Mol Microbiol (1995) 3.37

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.34

DNA recombination: the replication connection. Trends Biochem Sci (1999) 3.32

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1997) 3.27

DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature (1995) 3.15

XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics (1992) 3.15

DNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA. Proc Natl Acad Sci U S A (1998) 3.05

Rad52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss. Genetics (1985) 3.01

Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol (1995) 2.96

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell (1999) 2.89

Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev (1998) 2.77

Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol Cell (2000) 2.76

Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev (1996) 2.76

"Break copy" duplication: a model for chromosome fragment formation in Saccharomyces cerevisiae. Genetics (1997) 2.76

Multiple pathways for homologous recombination in Saccharomyces cerevisiae. Genetics (1995) 2.68

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.51

RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis. Genetics (1997) 2.36

Physical lengths of meiotic and mitotic gene conversion tracts in Saccharomyces cerevisiae. Genetics (1988) 2.36

Healing of broken linear dicentric chromosomes in yeast. Genetics (1984) 2.35

Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol Cell Biol (2001) 2.34

Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31

Use of a chromosomal inverted repeat to demonstrate that the RAD51 and RAD52 genes of Saccharomyces cerevisiae have different roles in mitotic recombination. Genetics (1994) 2.15

Two alternative mechanisms for initiation of DNA replication forks in bacteriophage T4: priming by RNA polymerase and by recombination. Proc Natl Acad Sci U S A (1982) 2.11

Characterization of null mutants of the RAD55 gene of Saccharomyces cerevisiae: effects of temperature, osmotic strength and mating type. Genetics (1987) 2.05

Requirement of yeast SGS1 and SRS2 genes for replication and transcription. Science (1999) 2.01

Recombination by replication. Cell (1996) 1.96

Recombination and recombination-dependent DNA replication in bacteriophage T4. Annu Rev Genet (1998) 1.87

RAD51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates. Mol Cell Biol (2000) 1.71

Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway. Genetics (1999) 1.67

Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous. Genetics (1990) 1.66

Double-strand-break repair recombination in Escherichia coli: physical evidence for a DNA replication mechanism in vivo. Genes Dev (1999) 1.56

Double-strand end repair via the RecBC pathway in Escherichia coli primes DNA replication. Genes Dev (1999) 1.49

Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene. Mutat Res (2000) 1.44

Human Rad52 protein promotes single-strand DNA annealing followed by branch migration. Mutat Res (1997) 1.42

Aberrant double-strand break repair in rad51 mutants of Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.40

Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication. Genetics (1996) 1.38

Single strand DNA binding and annealing activities in the yeast recombination factor Rad59. J Biol Chem (1999) 1.32

Characterization of the role played by the RAD59 gene of Saccharomyces cerevisiae in ectopic recombination. Curr Genet (1999) 1.05

The Saccharomyces cerevisiae RAD54 gene is important but not essential for natural homothallic mating-type switching. Mol Gen Genet (1999) 0.89

Articles by these authors

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. N Engl J Med (1996) 15.04

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

Lethal disruption of the yeast actin gene by integrative DNA transformation. Science (1982) 6.88

Text-based discovery in biomedicine: the architecture of the DAD-system. Proc AMIA Symp (2000) 6.10

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J (1990) 5.94

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol Cell Biol (1992) 5.71

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08

Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol Cell Biol (1992) 4.97

Meiotic gene conversion and crossing over between dispersed homologous sequences occurs frequently in Saccharomyces cerevisiae. Genetics (1987) 4.94

Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure. The Pacing Therapies for Congestive Heart Failure Study Group. The Guidant Congestive Heart Failure Research Group. Circulation (1999) 4.64

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49

Homothallic mating type switching generates lethal chromosome breaks in rad52 strains of Saccharomyces cerevisiae. Mol Cell Biol (1981) 4.41

Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics (1996) 4.33

Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol Cell Biol (1988) 4.02

Meiotic recombination in yeast: alteration by multiple heterozygosities. Science (1987) 3.93

Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications. N Engl J Med (1996) 3.87

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. Science (1995) 3.87

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell (2001) 3.74

Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr Biol (1998) 3.63

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events. Mol Cell Biol (1994) 3.40

Analysis of meiosis-defective mutations in yeast by physical monitoring of recombination. Genetics (1986) 3.38

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.34

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc Natl Acad Sci U S A (1997) 3.29

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1997) 3.27

An evaluation of the relatedness of proteins based on comparison of amino acid sequences. J Mol Biol (1970) 3.26

Characterization of a mutation in yeast causing nonrandom chromosome loss during mitosis. Genetics (1978) 3.21

DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature (1995) 3.15

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks. Nature (1996) 3.07

Rad52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss. Genetics (1985) 3.01

The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1992) 2.96

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. Cell (1980) 2.95

Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae. Genetics (1989) 2.93

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus. Genetics (1992) 2.92

RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.90

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell (1999) 2.89

Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae. Genetics (1993) 2.83

A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling. Mol Cell Biol (1999) 2.80

Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol Cell Biol (1998) 2.79

The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics (1994) 2.70

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55

Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.54

Rearrangements of highly polymorphic regions near telomeres of Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.52

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev (1993) 2.48

Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation. J Biol Chem (1999) 2.47

NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42

Position effects in ectopic and allelic mitotic recombination in Saccharomyces cerevisiae. Genetics (1989) 2.41

Length and distribution of meiotic gene conversion tracts and crossovers in Saccharomyces cerevisiae. Genetics (1989) 2.38

Meiotic and mitotic behavior of dicentric chromosomes in Saccharomyces cerevisiae. Genetics (1984) 2.37

Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37

Healing of broken linear dicentric chromosomes in yeast. Genetics (1984) 2.35

Physical monitoring of mating type switching in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.33

Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31

Evidence of Chromosomal Breaks near the Mating-Type Locus of SACCHAROMYCES CEREVISIAE That Accompany MATalpha xMATalpha Matings. Genetics (1981) 2.28

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis. Proc Natl Acad Sci U S A (1990) 2.26

Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. Genetics (1988) 2.15

Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr Biol (1999) 2.11

Deletions and single base pair changes in the yeast mating type locus that prevent homothallic mating type conversions. Proc Natl Acad Sci U S A (1983) 2.09

Heteroduplex formation and mismatch repair of the "stuck" mutation during mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.98

A 700 bp cis-acting region controls mating-type dependent recombination along the entire left arm of yeast chromosome III. Cell (1996) 1.94

Physical monitoring of meiotic recombination in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1984) 1.94

Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen. J Immunol (1987) 1.92

Mitotic recombination among subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1990) 1.91

Mismatch repair-induced meiotic recombination requires the pms1 gene product. Genetics (1990) 1.91

Colcemid inhibition of cell growth and the characterization of a colcemid-binding activity in Saccharomyces cerevisiae. J Cell Biol (1972) 1.89

Bisexual mating behavior in a diploid of Saccharomyces cerevisiae: evidence for genetically controlled non-random chromosome loss during vegetative growth. Genetics (1974) 1.88

The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates. J Clin Invest (1993) 1.84

The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem (1993) 1.80

The subtelomeric Y' repeat family in Saccharomyces cerevisiae: an experimental system for repeated sequence evolution. Genetics (1990) 1.79

Giardiasis: association with homosexuality. Ann Intern Med (1978) 1.75

Messenger ribonucleic acid and protein metabolism during sporulation of Saccharomyces cerevisiae. J Bacteriol (1980) 1.73

Structure-function relationships of the adenovirus DNA-binding protein. J Biol Chem (1979) 1.72

The distribution of plasma lipoproteins in middle-aged male runners. Metabolism (1976) 1.69

Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway. Genetics (1999) 1.67

Internal olefins to linear amines. Science (2002) 1.64

Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b. EMBO J (1987) 1.60

Cell cycle dependency of sporulation in Saccharomyces cerevisiae. J Bacteriol (1972) 1.59

Lack of prognostic value of syncope in patients with Wolff-Parkinson-White syndrome. J Am Coll Cardiol (1991) 1.59

Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev (2000) 1.56

Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex. EMBO J (2000) 1.56

MATa donor preference in yeast mating-type switching: activation of a large chromosomal region for recombination. Genes Dev (1995) 1.54

Gene targeting by linear duplex DNA frequently occurs by assimilation of a single strand that is subject to preferential mismatch correction. Proc Natl Acad Sci U S A (1997) 1.53

Frequency and intensity of crack use as predictors of women's involvement in HIV-related sexual risk behaviors. Drug Alcohol Depend (2000) 1.49

Ribonucleoprotein particle appearing during sporulation in yeast. J Bacteriol (1978) 1.43

A CIS-Acting Mutation within the MATa Locus of SACCHAROMYCES CEREVISIAE That Prevents Efficient Homothallic Mating-Type Switching. Genetics (1980) 1.42

Mechanism of MAT alpha donor preference during mating-type switching of Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.41

Efficient sporulation of yeast in media buffered near pH6. J Bacteriol (1977) 1.40

Lack of efficacy of tranexamic acid in thrombocytopenic bleeding. Transfusion (1991) 1.40

A PRELIMINARY NOTE ON THE SIGNIFICANCE OF THE PHOSPHORUS INTAKE IN THE DIET AND BLOOD PHOSPHORUS CONCENTRATION, IN THE EXPERIMENTAL PRODUCTION OF CARIES-IMMUNITY AND CARIES-SUSCEPTIBILITY IN THE RAT. Science (1931) 1.39

Ropivacaine test dose in extradural anaesthesia. Br J Anaesth (1997) 1.39

Membrane potential defect in hygromycin B-resistant pma1 mutants of Saccharomyces cerevisiae. J Biol Chem (1988) 1.38

The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo. Mol Cell (2000) 1.37

Mutations preventing transpositions of yeast mating type alleles. Proc Natl Acad Sci U S A (1980) 1.36

Defective H(+)-ATPase of hygromycin B-resistant pma1 mutants fromSaccharomyces cerevisiae. J Biol Chem (1989) 1.32

RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev (2001) 1.32