Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.

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Published in Arch Biochem Biophys on September 01, 1996

Authors

C J Patten1, T J Smith, S E Murphy, M H Wang, J Lee, R E Tynes, P Koch, C S Yang

Author Affiliations

1: Department of Drug Metabolism, Sandoz Pharmaceuticals Corporation, Sandoz Research Institute, East Hanover, New Jersey 07936, USA.

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