Published in Endocrinology on October 01, 1996
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest (1998) 3.76
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest (1997) 2.73
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A (2005) 2.63
Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta (2007) 2.11
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. J Exp Med (2005) 2.06
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Cell Biol (1999) 2.05
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest (1997) 1.95
The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors. Br J Pharmacol (2013) 1.70
PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1. J Clin Invest (2005) 1.49
The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation. J Biol Chem (2013) 1.49
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol Cell Biol (2002) 1.48
FSP27 promotes lipid droplet clustering and then fusion to regulate triglyceride accumulation. PLoS One (2011) 1.30
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons. Proc Natl Acad Sci U S A (2008) 1.23
Discrete roles for peroxisome proliferator-activated receptor gamma and retinoid X receptor in recruiting nuclear receptor coactivators. Mol Cell Biol (2000) 1.15
Type II diabetes mellitus and cardiovascular risk factors: Current therapeutic approaches. Exp Clin Cardiol (2007) 1.15
Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br J Pharmacol (2009) 1.13
What obesity research tells us about epigenetic mechanisms. Philos Trans R Soc Lond B Biol Sci (2013) 1.11
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution. Br J Pharmacol (1999) 1.07
Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care (2007) 1.03
PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1. Nucl Recept Signal (2010) 0.98
PPAR and immune system--what do we know? Int Immunopharmacol (2002) 0.97
Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice. J Biol Chem (2010) 0.94
Agonism of Peroxisome Proliferator Receptor-Gamma may have Therapeutic Potential for Neuroinflammation and Parkinson's Disease. Curr Neuropharmacol (2007) 0.94
Heterodimeric interaction between retinoid X receptor alpha and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation. Mol Cell Biol (1997) 0.91
Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response. J Nutr Biochem (2012) 0.90
Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma. Curr Med Chem (2009) 0.90
Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells. Mol Cancer (2008) 0.89
Open channel block of Kv1.3 by rosiglitazone and troglitazone: Kv1.3 as the pharmacological target for rosiglitazone. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.89
Transcriptional Control of Vascular Smooth Muscle Cell Proliferation by Peroxisome Proliferator-Activated Receptor-gamma: Therapeutic Implications for Cardiovascular Diseases. PPAR Res (2008) 0.88
Peroxisome proliferator-activated receptor γ and colorectal cancer. World J Gastrointest Oncol (2010) 0.87
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner. PLoS One (2011) 0.84
Effects of PPARγ Ligands on Leukemia. PPAR Res (2012) 0.84
Effects of rosiglitazone on the configuration of action potentials and ion currents in canine ventricular cells. Br J Pharmacol (2011) 0.84
In vivo JNK activation in pancreatic β-cells leads to glucose intolerance caused by insulin resistance in pancreas. Diabetes (2013) 0.83
Flavonoids as dietary regulators of nuclear receptor activity. Food Funct (2013) 0.82
Pancreatic regulation of glucose homeostasis. Exp Mol Med (2016) 0.81
Lack of efficacy of troglitazone at clinically achievable concentrations, with or without 9-cis retinoic acid or cytotoxic agents, for hepatocellular carcinoma cell lines. Br J Cancer (2004) 0.80
Therapeutic implications of targeting energy metabolism in breast cancer. PPAR Res (2013) 0.80
Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolism. Br J Pharmacol (1999) 0.79
Activation of PPARγ by Rosiglitazone does not negatively impact male sex steroid hormones in diabetic rats. PPAR Res (2009) 0.78
Pioglitazone, PPARγ agonist, attenuates experimental autoimmune neuritis. Inflammation (2012) 0.78
Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings. Clin Exp Med (2016) 0.77
Targeting nuclear receptors with marine natural products. Mar Drugs (2014) 0.77
Arachidonic acid has a dominant effect to regulate lipogenic genes in 3T3-L1 adipocytes compared to omega-3 fatty acids. Food Nutr Res (2015) 0.77
Rosiglitazone modulates insulin-induced plasma membrane area changes in single 3T3-L1 adipocytes. J Membr Biol (2008) 0.77
Effect of Opuntia humifusa supplementation and acute exercise on insulin sensitivity and associations with PPAR-γ and PGC-1α protein expression in skeletal muscle of rats. Int J Mol Sci (2013) 0.76
The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. J Vet Med Sci (2013) 0.75
Pharmacogenetic studies update in type 2 diabetes mellitus. World J Diabetes (2016) 0.75
Activation of the Constitutive Androstane Receptor by Monophthalates. Chem Res Toxicol (2016) 0.75
The role of attention in the treatment of attention-maintained self-injurious behavior: noncontingent reinforcement and differential reinforcement of other behavior. J Appl Behav Anal (1993) 9.17
The functions of self-injurious behavior: an experimental-epidemiological analysis. J Appl Behav Anal (1994) 8.16
Trends in the hospital care of acute childhood asthma 1970-8: a regional study. Br Med J (1980) 6.72
A receptor in pituitary and hypothalamus that functions in growth hormone release. Science (1996) 5.45
Parasitism by virulent Treponema pallidum of host cell surfaces. Infect Immun (1977) 4.05
Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis. EMBO J (2000) 3.97
Follow-up study of two hundred admissions to a residential home. Age Ageing (1976) 3.81
Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology (2004) 3.54
DNA-dependent DNA polymerases I and II from normal human-blood lymphocytes. Proc Natl Acad Sci U S A (1972) 3.27
Acetylcholine receptor kinetics. A description from single-channel currents at snake neuromuscular junctions. Biophys J (1982) 3.26
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res Mol Brain Res (1997) 3.21
Concerning the Microscopic Structure of the Hypophysis Cerebri in Acromegaly: (Based on a Study of Tissues Removed at Operation from 35 Patients). Am J Pathol (1925) 2.95
Protein synthesis by Treponema pallidum extracted from infected rabbit tissue. Infect Immun (1974) 2.91
Initial characterization of monoclonal antibodies against human monocytes. Proc Natl Acad Sci U S A (1980) 2.61
Analysis of the reinforcement and extinction components in DRO contingencies with self-injury. J Appl Behav Anal (1993) 2.56
Viral and cellular DNA polymerase: comparison of activities with synthetic and natural RNA templates. Science (1972) 2.53
Extinction of self-injurious escape behavior with and without instructional fading. J Appl Behav Anal (1993) 2.52
An analysis of reinforcer substitutability using object manipulation and self-injury as competing responses. J Appl Behav Anal (1997) 2.47
Momentum and extinction effects on self-injurious escape behavior and noncompliance. J Appl Behav Anal (1994) 2.41
Isolation and tissue distribution of type-C virus and viral components from a gibbon ape (Hylobates lar) with lymphocytic leukemia. Virology (1978) 2.37
Global patterns in availability of emergency obstetric care. Int J Gynaecol Obstet (2006) 2.33
Determination of Indole-3-acetic Acid in Douglas Fir Using a Deuterated Analog and Selected Ion Monitoring: Comparison of Microquantities in Seedling and Adult Tree. Plant Physiol (1978) 2.26
Purification of Treponema pallidum from Infected Rabbit Tissue: Resolution into Two Treponemal Populations. Infect Immun (1974) 2.23
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science (1999) 2.21
Gentamicin resistance in Staphylococcus aureus. Lancet (1976) 2.18
An analysis of the reinforcing properties of hand mouthing. J Appl Behav Anal (1995) 2.18
Intracranial Chordoblastoma. Am J Pathol (1929) 2.17
The rôle of the cells of Schwann in the formation of tumors of the peripheral nerves. Am J Pathol (1938) 2.15
Studies in Acromegaly: VII. The Microscopical Structure of the Adenomas in Acromegalic Dyspituitarism (Fugitive Acromegaly). Am J Pathol (1928) 2.12
Essential role of growth hormone in ischemia-induced retinal neovascularization. Science (1997) 2.11
Activation of PPARdelta alters lipid metabolism in db/db mice. FEBS Lett (2000) 2.10
Reemergence and extinction of self-injurious escape behavior during stimulus (instructional) fading. J Appl Behav Anal (1994) 2.05
Regulation of Carbon Partitioning to Respiration during Dark Ammonium Assimilation by the Green Alga Selenastrum minutum. Plant Physiol (1990) 1.98
Hyaluronate and invasiveness of the rabbit V2 carcinoma. Proc Natl Acad Sci U S A (1979) 1.96
Effects of exposure to mercury in the manufacture of chlorine. Am Ind Hyg Assoc J (1971) 1.88
Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting. Nature (1989) 1.88
Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression. Endocrinology (1998) 1.84
Within-session patterns of self-injury as indicators of behavioral function. Res Dev Disabil (1994) 1.84
Current research on the influence of establishing operations on behavior in applied settings. J Appl Behav Anal (2000) 1.79
The United Nations Process Indicators for emergency obstetric care: Reflections based on a decade of experience. Int J Gynaecol Obstet (2006) 1.77
Tetrahydroaminoacridine-lecithin combination treatment in patients with intermediate-stage Alzheimer's disease. Results of a Canadian double-blind, crossover, multicenter study. N Engl J Med (1990) 1.74
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc Natl Acad Sci U S A (2001) 1.74
Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF-receptor antagonist kadsurenone. Biochem Biophys Res Commun (1985) 1.71
Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem (1997) 1.69
Single-channel acetylcholine receptor kinetics. Biophys J (1984) 1.69
Conformationally restricted bicyclic analogs of somatostatin. Proc Natl Acad Sci U S A (1978) 1.69
The role and regulation of tumour-associated hyaluronan. Ciba Found Symp (1989) 1.68
Further Notes on the Cerebellar Medulloblastomas: The Effect of Roentgen Radiation. Am J Pathol (1930) 1.68
The isolation and metabolism of brown fat cells. J Biol Chem (1967) 1.66
Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects. J Biol Chem (1999) 1.65
Anabolic potential of virulent Treponema pallidum. Infect Immun (1977) 1.63
Distribution of total mercury and methyl mercury in water, sediment, and fish from south Florida estuaries. Arch Environ Contam Toxicol (1998) 1.63
Microcircuitry of the dark-adapted cat retina: functional architecture of the rod-cone network. J Neurosci (1986) 1.61
Low-density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells. Blood (1978) 1.60
Effectiveness of psychiatric intervention with somatization disorder patients: improved outcomes at reduced costs. Gen Hosp Psychiatry (1994) 1.57
Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppression. Neuron (1988) 1.55
Electronic and magnetic properties of quasifreestanding graphene on Ni. Phys Rev Lett (2008) 1.54
A simple and safe technique of left ventricular venting. Ann Thorac Surg (1992) 1.53
Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem Biophys Res Commun (1996) 1.53
Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation. J Mol Biol (2000) 1.53
DNA polymerases in human lymphoblastoid cells infected with simian sarcoma virus. Biochim Biophys Acta (1974) 1.52
Relationship between NH(4) Assimilation Rate and in Vivo Phosphoenolpyruvate Carboxylase Activity : Regulation of Anaplerotic Carbon Flow in the Green Alga Selenastrum minutum. Plant Physiol (1990) 1.52
Mode of action of insulin in the regulation of protein biosynthesis in muscle. Recent Prog Horm Res (1968) 1.52
Are private nursing home beds a drain or a gain for the acute sector? Age Ageing (1998) 1.51
Amyotrophic lateral sclerosis patient antibodies label Ca2+ channel alpha 1 subunit. Ann Neurol (1994) 1.50
Interactions between human tumor cells and fibroblasts stimulate hyaluronate synthesis. Proc Natl Acad Sci U S A (1984) 1.50
Aromatase enzyme activity and sex determination in chickens. Science (1992) 1.49
Hemangiomas of Cerebellum and Retina (Lindau's Disease): With the Report of a Case. Trans Am Ophthalmol Soc (1928) 1.49
Voltage-dependent gating of veratridine-modified Na channels. J Gen Physiol (1986) 1.47
Medical and nursing needs of elderly patients admitted to acute medical beds. Age Ageing (1979) 1.47
Release of repressor control of ribonucleotide reductase by thymine starvation. J Biol Chem (1965) 1.46
Contribution from geriatric medicine within acute medical wards. Br Med J (1979) 1.46
Tumor cell stimulation of collagenase production by fibroblasts. Biochem Biophys Res Commun (1982) 1.45
Architecture of rod and cone circuits to the on-beta ganglion cell. J Neurosci (1988) 1.43
A potent cyclic hexapeptide analogue of somatostatin. Nature (1981) 1.42
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res (1993) 1.41
Research note: Estimating maternal deaths averted: A field-based methodology. Int J Gynaecol Obstet (2005) 1.41
The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. Ann Neurol (1994) 1.40
Receptor for motilin identified in the human gastrointestinal system. Science (1999) 1.39
Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study. Blood (1995) 1.38
Switching endotracheal tubes. J Oral Maxillofac Surg (1995) 1.38
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science (1998) 1.36
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Mol Cell Biol (1997) 1.34
Bioactive conformation of luteinizing hormone-releasing hormone: evidence from a conformationally constrained analog. Science (1980) 1.32
Air-pressure-induced colon injury during diagnostic colonoscopy. Gastroenterology (1980) 1.31
Monoclonal antibody preparation and purification of a tumor cell collagenase-stimulatory factor. Cancer Res (1989) 1.31
Observer variation in the clinical assessment of stroke. Age Ageing (1976) 1.31
A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. J Neurosci (1992) 1.30
Human DNA polymerase 3 (R-DNA polymerase): distinction from DNA polymerase I and reverse transcriptase. Science (1974) 1.30
Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study. Blood (1993) 1.30
Size at birth from 37 - 41 weeks gestation: ethnic standards for British infants of both sexes. J Hum Nutr (1981) 1.29