Published in Brain Res Mol Brain Res on August 01, 1997
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J Clin Invest (2006) 3.81
Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol (2006) 3.61
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A (2004) 2.99
Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol (2003) 2.73
Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci (2008) 2.45
Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron (2012) 2.30
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans. Diabetes (2010) 2.01
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner. Biol Psychiatry (2009) 1.87
Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci U S A (2009) 1.82
G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives. Pharmacol Rev (2014) 1.82
Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. Eur J Neurosci (2008) 1.74
Stomach ghrelin-secreting cells as food-entrainable circadian clocks. Proc Natl Acad Sci U S A (2009) 1.72
Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol (2003) 1.62
Ghrelin increases intake of rewarding food in rodents. Addict Biol (2010) 1.61
Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity. J Clin Invest (2002) 1.60
Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery. Obes Surg (2012) 1.50
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. J Neurosci (2009) 1.50
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. PLoS One (2008) 1.49
The influences of diet and exercise on mental health through hormesis. Ageing Res Rev (2007) 1.34
Ghrelin. Mol Metab (2015) 1.29
Brain circuits regulating energy homeostasis. Regul Pept (2008) 1.24
Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Mol Cell Neurosci (2003) 1.21
Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice. Neuroscience (2009) 1.21
Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight. Peptides (2009) 1.19
Ghrelin in central neurons. Curr Neuropharmacol (2009) 1.17
Circadian adaptations to meal timing: neuroendocrine mechanisms. Front Neurosci (2013) 1.15
Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Mol Endocrinol (2009) 1.14
Striatocortical pathway dysfunction in addiction and obesity: differences and similarities. Crit Rev Biochem Mol Biol (2012) 1.14
Ghrelin signaling in the ventral hippocampus stimulates learned and motivational aspects of feeding via PI3K-Akt signaling. Biol Psychiatry (2012) 1.14
Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells. Mol Endocrinol (2011) 1.13
Neuronal control of energy homeostasis. FEBS Lett (2007) 1.13
[125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Br J Pharmacol (2001) 1.11
Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin. Regul Pept (2007) 1.11
NPY Y1 receptor is involved in ghrelin- and fasting-induced increases in foraging, food hoarding, and food intake. Am J Physiol Regul Integr Comp Physiol (2007) 1.09
Inhibition of adipogenesis by ghrelin. Mol Biol Cell (2004) 1.09
Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neurons. Alcohol Clin Exp Res (2010) 1.08
Importance of reward and prefrontal circuitry in hunger and satiety: Prader-Willi syndrome vs simple obesity. Int J Obes (Lond) (2011) 1.07
Ghrelin's Roles in Stress, Mood, and Anxiety Regulation. Int J Pept (2010) 1.06
Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse. J Comp Neurol (2014) 1.05
Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiol Behav (2010) 1.05
Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans. J Neurosci (2011) 1.04
The role of ghrelin in reward-based eating. Biol Psychiatry (2012) 1.03
Hedonic and incentive signals for body weight control. Rev Endocr Metab Disord (2011) 1.02
Bariatric surgery for extreme adolescent obesity: indications, outcomes, and physiologic effects on the gut-brain axis. Pathophysiology (2008) 1.01
Cognitive and neuronal systems underlying obesity. Physiol Behav (2012) 1.00
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice. Am J Physiol Regul Integr Comp Physiol (2009) 0.99
Adult-onset deficiency in growth hormone and insulin-like growth factor-I alters oligodendrocyte turnover in the corpus callosum. Glia (2009) 0.98
Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus. Brain Res (2008) 0.98
A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear. Mol Psychiatry (2013) 0.98
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain. J Comp Neurol (2012) 0.97
Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling. J Biol Chem (2012) 0.97
Cognitive enhancing effects of ghrelin receptor agonists. Psychopharmacology (Berl) (2009) 0.97
Sex differences in the neural circuit that mediates female sexual receptivity. Front Neuroendocrinol (2011) 0.96
Forebrain networks and the control of feeding by environmental learned cues. Physiol Behav (2013) 0.96
Intestinal feedback signaling and satiety. Physiol Behav (2011) 0.94
Ghrelin in the CNS: from hunger to a rewarding and memorable meal? Brain Res Rev (2008) 0.93
Disruption of cue-potentiated feeding in mice with blocked ghrelin signaling. Physiol Behav (2012) 0.93
The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence. PLoS One (2012) 0.93
Ghrelin's second life: from appetite stimulator to glucose regulator. World J Gastroenterol (2012) 0.93
MTII attenuates ghrelin- and food deprivation-induced increases in food hoarding and food intake. Horm Behav (2007) 0.93
Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors. Addict Biol (2011) 0.92
Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor. Br J Pharmacol (2013) 0.92
Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway. Br J Pharmacol (2006) 0.92
The neuropathology of obesity: insights from human disease. Acta Neuropathol (2013) 0.91
Ghrelin is an orexigenic peptide and elicits anxiety-like behaviors following administration into discrete regions of the hypothalamus. Behav Brain Res (2011) 0.91
Inhibition of pancreatic protein secretion by ghrelin in the rat. J Physiol (2001) 0.91
Immunohistochemical evidence for an endocrine/paracrine role for ghrelin in the reproductive tissues of sheep. Reprod Biol Endocrinol (2005) 0.91
Ghrelin: central nervous system sites of action in regulation of energy balance. Int J Pept (2010) 0.90
Ghrelin: central and peripheral implications in anorexia nervosa. Front Endocrinol (Lausanne) (2013) 0.90
Neuropeptides as targets for the development of anticonvulsant drugs. Mol Neurobiol (2014) 0.90
Role of appetite-regulating peptides in the pathophysiology of addiction: implications for pharmacotherapy. CNS Drugs (2014) 0.88
Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger-arousal network. Eur J Neurosci (2009) 0.87
Ghrelin - a pleiotropic hormone secreted from endocrine x/a-like cells of the stomach. Front Neurosci (2012) 0.87
Functional organization of neuronal and humoral signals regulating feeding behavior. Annu Rev Nutr (2013) 0.87
The central nervous system sites mediating the orexigenic actions of ghrelin. Annu Rev Physiol (2013) 0.87
Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism. Mol Metab (2012) 0.87
Systemic ghrelin sensitizes cocaine-induced hyperlocomotion in rats. Regul Pept (2007) 0.87
Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward. Front Neurosci (2013) 0.87
Physiological roles revealed by ghrelin and ghrelin receptor deficient mice. Peptides (2011) 0.87
Ghrelin signalling on food reward: a salient link between the gut and the mesolimbic system. J Neuroendocrinol (2015) 0.87
Anamorelin hydrochloride for the treatment of cancer-anorexia-cachexia in NSCLC. Expert Opin Pharmacother (2015) 0.86
Ghrelin-induced hypothermia: a physiological basis but no clinical risk. Physiol Behav (2011) 0.86
Role of ghrelin system in neuroprotection and cognitive functions: implications in Alzheimer's disease. Peptides (2011) 0.86
Analysis of brain nuclei accessible to ghrelin present in the cerebrospinal fluid. Neuroscience (2013) 0.86
Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models. Front Neurosci (2013) 0.86
Leptin inhibits food-deprivation-induced increases in food intake and food hoarding. Am J Physiol Regul Integr Comp Physiol (2008) 0.86
Ghrelin, appetite regulation, and food reward: interaction with chronic stress. Int J Pept (2011) 0.86
Ghrelin receptor signaling: a promising therapeutic target for metabolic syndrome and cognitive dysfunction. CNS Neurol Disord Drug Targets (2010) 0.85
Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus. Proc Natl Acad Sci U S A (2013) 0.85
Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system. Addict Biol (2011) 0.85
G Protein and β-arrestin signaling bias at the ghrelin receptor. J Biol Chem (2014) 0.85
Growth hormone secretagogue receptor (GHS-R1a) knockout mice exhibit improved spatial memory and deficits in contextual memory. Behav Brain Res (2012) 0.85
Ghrelin is an Osteoblast Mitogen and Increases Osteoclastic Bone Resorption In Vitro. Int J Pept (2011) 0.84
Ghrelin receptor (GHS-R1A) antagonism suppresses both alcohol consumption and the alcohol deprivation effect in rats following long-term voluntary alcohol consumption. PLoS One (2013) 0.84
A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice. PLoS One (2012) 0.84
The multiple faces of glucagon-like peptide-1--obesity, appetite, and stress: what is next? A review. Dig Dis Sci (2007) 0.84
Glucocorticoid signaling in the arcuate nucleus modulates hepatic insulin sensitivity. Diabetes (2011) 0.84
Ablation of AgRP neurons impairs adaption to restricted feeding. Mol Metab (2014) 0.84
Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin. Int J Obes (Lond) (2015) 0.84
Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats. Psychopharmacology (Berl) (2011) 0.83
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature (1992) 9.96
The role of attention in the treatment of attention-maintained self-injurious behavior: noncontingent reinforcement and differential reinforcement of other behavior. J Appl Behav Anal (1993) 9.17
The functions of self-injurious behavior: an experimental-epidemiological analysis. J Appl Behav Anal (1994) 8.16
GENIES: a natural-language processing system for the extraction of molecular pathways from journal articles. Bioinformatics (2001) 6.05
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev (1998) 5.96
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. Dev Cell (2001) 5.82
A receptor in pituitary and hypothalamus that functions in growth hormone release. Science (1996) 5.45
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell (1998) 5.28
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature (2000) 4.68
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nat Genet (2000) 4.57
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science (1994) 4.57
Antigenic variation in Trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules. Cell (1984) 4.03
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene (2001) 3.96
Follow-up study of two hundred admissions to a residential home. Age Ageing (1976) 3.81
Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation (1992) 3.73
Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3' end. Cell (1981) 3.65
Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology (2004) 3.54
Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. Proc Natl Acad Sci U S A (1998) 3.35
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell (1995) 3.33
DNA-dependent DNA polymerases I and II from normal human-blood lymphocytes. Proc Natl Acad Sci U S A (1972) 3.27
Structure of the growing telomeres of Trypanosomes. Cell (1984) 3.24
Role of the Kv4.3 K+ channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res (1996) 3.23
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature (1997) 3.14
High rate of recombination throughout the human immunodeficiency virus type 1 genome. J Virol (2000) 3.09
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans. Nature (1994) 2.92
Distribution of orexin receptor mRNA in the rat brain. FEBS Lett (1998) 2.90
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. Nucleic Acids Res (1982) 2.87
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet (2001) 2.84
gamma-beta-Thalassaemia studies showing that deletion of the gamma- and delta-genes influences beta-globin gene expression in man. Nature (1980) 2.68
Tandem repetition of the 5' mini-exon of variant surface glycoprotein genes: a multiple promoter for VSG gene transcription? Cell (1983) 2.67
Initial characterization of monoclonal antibodies against human monocytes. Proc Natl Acad Sci U S A (1980) 2.61
Analysis of the reinforcement and extinction components in DRO contingencies with self-injury. J Appl Behav Anal (1993) 2.56
Chromosome rearrangements in Trypanosoma brucei. Cell (1984) 2.56
Nucleotide sequence of a ripening-related cDNA from avocado fruit. Plant Mol Biol (1990) 2.53
Viral and cellular DNA polymerase: comparison of activities with synthetic and natural RNA templates. Science (1972) 2.53
Extinction of self-injurious escape behavior with and without instructional fading. J Appl Behav Anal (1993) 2.52
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat Struct Biol (2000) 2.49
Phylogenetic relationships among eight Eimeria species infecting domestic fowl inferred using complete small subunit ribosomal DNA sequences. J Parasitol (1997) 2.49
An analysis of reinforcer substitutability using object manipulation and self-injury as competing responses. J Appl Behav Anal (1997) 2.47
Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circ Res (1999) 2.47
Case study of the effects of atmospheric aerosols and regional haze on agriculture: an opportunity to enhance crop yields in China through emission controls? Proc Natl Acad Sci U S A (1999) 2.44
Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. J Bacteriol (1996) 2.43
Momentum and extinction effects on self-injurious escape behavior and noncompliance. J Appl Behav Anal (1994) 2.41
Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response. J Bacteriol (1994) 2.37
Isolation and tissue distribution of type-C virus and viral components from a gibbon ape (Hylobates lar) with lymphocytic leukemia. Virology (1978) 2.37
Determination of Indole-3-acetic Acid in Douglas Fir Using a Deuterated Analog and Selected Ion Monitoring: Comparison of Microquantities in Seedling and Adult Tree. Plant Physiol (1978) 2.26
Mechanism of antigenic variation in Mycoplasma pulmonis: interwoven, site-specific DNA inversions. Mol Microbiol (1995) 2.26
PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Nucleic Acids Res (2001) 2.23
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science (1999) 2.21
Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition. J Biol Chem (1994) 2.21
Gentamicin resistance in Staphylococcus aureus. Lancet (1976) 2.18
An analysis of the reinforcing properties of hand mouthing. J Appl Behav Anal (1995) 2.18
Sequence analysis of ripening-related cytochrome P-450 cDNAs from avocado fruit. Proc Natl Acad Sci U S A (1990) 2.17
An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome. Nucleic Acids Res (1982) 2.16
Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection. Infect Immun (1997) 2.14
Subtherapeutic levels of antibiotics in poultry feeds and their effects on weight gain, feed efficiency, and bacterial cholyltaurine hydrolase activity. Appl Environ Microbiol (1987) 2.14
Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13
Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J Bacteriol (1996) 2.13
Essential role of growth hormone in ischemia-induced retinal neovascularization. Science (1997) 2.11
Conserved sequences and transcription of the hsp70 gene family in Trypanosoma brucei. Mol Cell Biol (1986) 2.11
Activation of PPARdelta alters lipid metabolism in db/db mice. FEBS Lett (2000) 2.10
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res (1999) 2.09
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4. Immunity (1998) 2.08
Chromosome-sized DNA molecules of Plasmodium falciparum. Science (1985) 2.06
Homologous recombination and stable transfection in the parasitic protozoan Trypanosoma brucei. Science (1990) 2.06
Reemergence and extinction of self-injurious escape behavior during stimulus (instructional) fading. J Appl Behav Anal (1994) 2.05
Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. Thorax (1998) 2.04
Beyond synexpression relationships: local clustering of time-shifted and inverted gene expression profiles identifies new, biologically relevant interactions. J Mol Biol (2001) 2.03
Procyclic acidic repetitive protein (PARP) genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei. Mol Cell Biol (1990) 2.01
Discovery of a receptor related to the galanin receptors. FEBS Lett (1999) 2.01
Functional expression of Drosophila para sodium channels. Modulation by the membrane protein TipE and toxin pharmacology. J Gen Physiol (1997) 1.99
Differential distribution of 5HT1D- and 5HT1B-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new antimigraine drugs. Cephalalgia (1997) 1.99
The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements at its border and absence of promoter-associated sequences. J Mol Biol (1983) 1.98
Regulation of Carbon Partitioning to Respiration during Dark Ammonium Assimilation by the Green Alga Selenastrum minutum. Plant Physiol (1990) 1.98
Pharmacological characterization of recombinant human and rat P2X receptor subtypes. Eur J Pharmacol (1999) 1.95
Orphan G-protein-coupled receptors and natural ligand discovery. Trends Pharmacol Sci (2001) 1.94
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein. Neuroscience (1999) 1.88
Effects of exposure to mercury in the manufacture of chlorine. Am Ind Hyg Assoc J (1971) 1.88
Kinectin, a major kinesin-binding protein on ER. J Cell Biol (1992) 1.87
Heat shock genes: regulatory role for differentiation in parasitic protozoa. Science (1985) 1.85
Within-session patterns of self-injury as indicators of behavioral function. Res Dev Disabil (1994) 1.84
Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a. J Med Chem (2000) 1.84
Lactobacilli and bile salt hydrolase in the murine intestinal tract. Appl Environ Microbiol (1989) 1.84
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. Transgenic Res (2000) 1.83