Published in Br J Pharmacol on March 01, 1996
Purinergic signalling in the gastrointestinal tract and related organs in health and disease. Purinergic Signal (2013) 0.95
Is there a basis for distinguishing two types of P2-purinoceptor? Gen Pharmacol (1985) 9.20
Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol (1993) 5.64
Nomenclature and classification of purinoceptors. Pharmacol Rev (1994) 5.32
The use of the slowly degradable analog, alpha, beta-methylene ATP, to produce desensitisation of the P2-purinoceptor: effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder. Eur J Pharmacol (1982) 3.52
Cloning and functional expression of a brain G-protein-coupled ATP receptor. FEBS Lett (1993) 3.38
Suramin antagonizes responses to P2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli. Br J Pharmacol (1990) 3.34
Further subclassification of ATP receptors based on agonist studies. Trends Pharmacol Sci (1991) 3.00
Evidence that ATP acts as a co-transmitter with noradrenaline in sympathetic nerves supplying the guinea-pig vas deferens. Eur J Pharmacol (1983) 2.40
Suramin is a slowly-equilibrating but competitive antagonist at P2x-receptors in the rabbit isolated ear artery. Br J Pharmacol (1990) 2.23
ATP analogues and the guinea-pig taenia coli: a comparison of the structure-activity relationships of ectonucleotidases with those of the P2-purinoceptor. Eur J Pharmacol (1986) 2.07
P2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci (1995) 2.05
Adenosine receptor subtypes. Trends Pharmacol Sci (1993) 1.99
The effects of some possible inhibitors of ectonucleotidases on the breakdown and pharmacological effects of ATP in the guinea-pig urinary bladder. Gen Pharmacol (1989) 1.98
The structure-activity relationships of ectonucleotidases and of excitatory P2-purinoceptors: evidence that dephosphorylation of ATP analogues reduces pharmacological potency. Eur J Pharmacol (1987) 1.94
Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends Pharmacol Sci (1989) 1.88
Inhibitory effects of adenine nucleotide analogs on the isolated guinea-pig taenia coli. J Pharmacol Exp Ther (1975) 1.82
Expression of a cloned P2Y purinergic receptor that couples to phospholipase C. Mol Pharmacol (1994) 1.76
Evidence for a vasoconstriction-mediating receptor for UTP, distinct from the P2 purinoceptor, in rabbit ear artery. Naunyn Schmiedebergs Arch Pharmacol (1987) 1.68
Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase. Br J Pharmacol (1995) 1.57
Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: suramin-sensitive and suramin-insensitive components in the contractile effect of ATP. Naunyn Schmiedebergs Arch Pharmacol (1990) 1.52
How should P2X purinoceptors be classified pharmacologically? Trends Pharmacol Sci (1995) 1.37
A study of the purinoceptors mediating contraction in the rat colon. Br J Pharmacol (1990) 1.36
Characterization of P1-purinoceptors on rat duodenum and urinary bladder. Br J Pharmacol (1992) 1.35
Characterization of the P1-purinoceptors mediating contraction of the rat colon muscularis mucosae. Br J Pharmacol (1992) 1.34
Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C. J Biol Chem (1994) 1.33
Cloning of rat and mouse P2Y purinoceptors. Biochem Biophys Res Commun (1995) 1.30
The regulation of aortic endothelial cells by purines and pyrimidines involves co-existing P2y-purinoceptors and nucleotide receptors linked to phospholipase C. Br J Pharmacol (1993) 1.25
Evidence for two separate vasoconstriction-mediating nucleotide receptors, both distinct from the P2x-receptor, in rabbit basilar artery: a receptor for pyrimidine nucleotides and a receptor for purine nucleotides. Naunyn Schmiedebergs Arch Pharmacol (1990) 1.24
Recent developments in the classification and functional significance of receptors for ATP and UTP, evidence for nucleotide receptors. Life Sci (1992) 1.23
Effects of purines on the longitudinal muscle of the rat colon. Br J Pharmacol (1992) 1.17
Neuronal "nucleotide" receptor linked to phospholipase C and phospholipase D? Stimulation of PC12 cells by ATP analogues and UTP. Mol Pharmacol (1992) 1.17
The ontogeny of purinoceptors in rat urinary bladder and duodenum. Br J Pharmacol (1990) 1.16
Constriction of the smooth muscle of rat tail and femoral arteries and dog saphenous vein is induced by uridine triphosphate via 'pyrimidinoceptors', and by adenosine triphosphate via P2x purinoceptors. Blood Vessels (1990) 1.10
Pharmacological analysis of ecto-ATPase inhibition: evidence for combined enzyme inhibition and receptor antagonism in P2X-purinoceptor ligands. Br J Pharmacol (1994) 1.10
Cloning and characterisation of a bovine P2Y receptor. Biochem Biophys Res Commun (1995) 1.08
Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells. Mol Pharmacol (1994) 1.05
P2Y purinoceptor and nucleotide receptor-induced relaxation of precontracted bovine aortic collateral artery rings: differential sensitivity to suramin and indomethacin. J Pharmacol Exp Ther (1994) 1.05
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae. Br J Pharmacol (1996) 0.99
Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum. Br J Pharmacol (1995) 0.96
Evidence from desensitization studies for distinct receptors for ATP and UTP on the rat superior cervical ganglion. Br J Pharmacol (1994) 0.89
Contractile effects of uridine 5'-triphosphate in the rat duodenum. Br J Pharmacol (1994) 0.86
Degradation of adenosine by extracellular adenosine deaminase in the rat duodenum. Gen Pharmacol (1988) 0.86
Desensitization of the P2-purinoceptors on the rat colon muscularis mucosae. Br J Pharmacol (1993) 0.82
ATP analogues and the guinea-pig taenia coli: a comparison of the structure-activity relationships of ectonucleotidases with those of the P2-purinoceptor. Eur J Pharmacol (1986) 2.07
Adenosine receptor subtypes. Trends Pharmacol Sci (1993) 1.99
The structure-activity relationships of ectonucleotidases and of excitatory P2-purinoceptors: evidence that dephosphorylation of ATP analogues reduces pharmacological potency. Eur J Pharmacol (1987) 1.94
The regulation of vascular function by P2 receptors: multiple sites and multiple receptors. Trends Pharmacol Sci (1998) 1.85
Pharmacological effects of isopolar phosphonate analogues of ATP on P2-purinoceptors in guinea-pig taenia coli and urinary bladder. Br J Pharmacol (1987) 1.36
A study of the purinoceptors mediating contraction in the rat colon. Br J Pharmacol (1990) 1.36
Characterization of P1-purinoceptors on rat duodenum and urinary bladder. Br J Pharmacol (1992) 1.35
Characterization of the P1-purinoceptors mediating contraction of the rat colon muscularis mucosae. Br J Pharmacol (1992) 1.34
Some pharmacological and biochemical interactions of the enantiomers of adenylyl 5'-(beta, gamma-methylene)-diphosphonate with the guinea-pig urinary bladder. Br J Pharmacol (1984) 1.30
Adenosine 5-diphosphate antagonists and human platelets: no evidence that aggregation and inhibition of stimulated adenylate cyclase are mediated by different receptors. Br J Pharmacol (1982) 1.29
Effects of RP and SP diastereoisomers of adenosine 5'-O-(1-thiodiphosphate) on human platelets. Br J Pharmacol (1981) 1.25
Evidence that P2Y4 nucleotide receptors are involved in the regulation of rat aortic smooth muscle cells by UTP and ATP. Br J Pharmacol (1998) 1.24
Subtypes of P2-purinoceptors. Studies using analogues of ATP. Ann N Y Acad Sci (1990) 1.21
L-AMP-PCP, an ATP receptor agonist in guinea-pig bladder, is inactive on taenia coli. Eur J Pharmacol (1985) 1.19
Pharmacological effects of L-AMP-PCP on ATP receptors in smooth muscle. Eur J Pharmacol (1986) 1.19
Effects of purines on the longitudinal muscle of the rat colon. Br J Pharmacol (1992) 1.17
The ontogeny of purinoceptors in rat urinary bladder and duodenum. Br J Pharmacol (1990) 1.16
5'-N-ethylcarboxamidoadenosine: a potent inhibitor of human platelet aggregation. Br J Pharmacol (1981) 1.12
Characterization of adenosine receptors in the rat isolated aorta. Gen Pharmacol (1994) 1.10
Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br J Pharmacol (1982) 1.09
Activation of multiple sites by adenosine analogues in the rat isolated aorta. Br J Pharmacol (1996) 1.04
Effects of analogues of adenine nucleotides on increases in intracellular calcium mediated by P2T-purinoceptors on human blood platelets. Br J Pharmacol (1993) 1.03
Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder. Br J Pharmacol (1994) 1.02
A common intracellular allosteric binding site for antagonists of the CXCR2 receptor. Br J Pharmacol (2010) 0.99
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae. Br J Pharmacol (1996) 0.99
Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate. Br J Pharmacol (1982) 0.97
Partial agonist behaviour of adenosine 5'-O-(2-thiodiphosphate) on human platelets. Br J Pharmacol (1981) 0.97
Characterization of adenosine receptors on rat ileum, ileal longitudinal muscle and muscularis mucosae. Eur J Pharmacol (1997) 0.96
The binding of 1,3-[3H]-dipropyl-8-cyclopentylxanthine to adenosine A1 receptors in rat smooth muscle preparations. Br J Pharmacol (1994) 0.96
Expression and functional analysis of chemokine receptors in human peripheral blood leukocyte populations. Cytokine (2001) 0.95
Effects of suramin on contractions of the guinea-pig vas deferens induced by analogues of adenosine 5'-triphosphate. Br J Pharmacol (1995) 0.94
SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor. Br J Pharmacol (2009) 0.92
Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery. Br J Pharmacol (1997) 0.90
Contractile effects of uridine 5'-triphosphate in the rat duodenum. Br J Pharmacol (1994) 0.86
Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues. Br J Pharmacol (2013) 0.81
Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta. Naunyn Schmiedebergs Arch Pharmacol (2000) 0.80
Enhancement of the response to purinergic agonists in P2Y1 transfected 1321N1 cells by antagonists suramin and PPADS. Br J Pharmacol (1997) 0.80
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart. Gen Pharmacol (1997) 0.79
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets. Br J Pharmacol (1999) 0.79
Differential inhibition by adenosine or by prostaglandin E1 of human platelet aggregation induced by adenosine 5'-O-(1-thiodiphosphate) and adenosine 5'-O-(2-thiodiphosphate). Br J Pharmacol (1982) 0.79
Reassessment of the pharmacology of Sphingosine-1-phosphate S1P3 receptor ligands using the DiscoveRx PathHunter™ and Ca2+ release functional assays. Br J Pharmacol (2012) 0.79
Analysis of second messenger pathways stimulated by different chemokines acting at the chemokine receptor CCR5. Biochem Pharmacol (2007) 0.79
Desensitization of the guinea-pig urinary bladder by the enantiomers of adenylyl 5'-(beta, gamma-methylene)-diphosphonate and by substance P. Br J Pharmacol (1984) 0.78
Effects of suramin on increases in cytosolic calcium and on inhibition of adenylate cyclase induced by adenosine 5'-diphosphate in human platelets. Biochem Pharmacol (1994) 0.78
Pharmacogenetic characterization of indacaterol, a novel beta 2-adrenoceptor agonist. Br J Pharmacol (2009) 0.78
Selective enhancement by an adenosine A1 receptor agonist of agents inducing contraction of the rat vas deferens. Naunyn Schmiedebergs Arch Pharmacol (1996) 0.77
Characterisation of ADP receptors. Adv Exp Med Biol (1985) 0.77
The ontogenetic profiles of the pre- and postjunctional adenosine receptors in the rat vas deferens. Br J Pharmacol (1996) 0.77
Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production. J Pineal Res (1997) 0.77
Effects of extracellular divalent cations on responses of human blood platelets to adenosine 5'-diphosphate. Biochem Pharmacol (1994) 0.77
Differential distribution of adenosine A2 receptors in the epididymal and prostatic portions of the rat vas deferens. Eur J Pharmacol (1996) 0.77
Ontogeny of P2-purinoceptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum. Br J Pharmacol (1997) 0.76
Platelet P2 receptors: from curiosity to clinical targets. J Auton Nerv Syst (2000) 0.75
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site. Eur J Pharmacol (1997) 0.75
Differential development of adenosine A1 and A2b receptors in the rat duodenum. Br J Pharmacol (1996) 0.75
Differential ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum. Eur J Pharmacol (1996) 0.75
Ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat distal colon. Naunyn Schmiedebergs Arch Pharmacol (1999) 0.75
Breakdown of extracellular ATP by the prostatic and epididymal ends of the guinea pig vas deferens. Eur J Pharmacol (2000) 0.75
Effects of allopurinol, erythro-9-(2-hydroxy-3-nonyl)adenine and S-(4-nitrobenzyl)-6-thioinosine on the degradation of adenosine 5'-triphosphate in the rat colon muscularis mucosae. J Auton Pharmacol (1999) 0.75
Effects of noradrenaline, the calcium ionophore A23187, forskolin, sodium nitroprusside and glibenclamide on the degradation of extracellular adenosine 5'-triphosphate by the rat isolated vas deferens. J Auton Pharmacol (1999) 0.75