Published in Dev Dyn on August 01, 1996
Expression of Prox1 during mouse cochlear development. J Comp Neurol (2006) 1.93
The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo. Genes Dev (2001) 1.54
Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development. PLoS One (2015) 1.39
Prox1 maintains muscle structure and growth in the developing heart. Development (2008) 1.21
Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue. EMBO Rep (2004) 1.16
Molecular and cellular aspects of amphibian lens regeneration. Prog Retin Eye Res (2010) 1.14
Prospero is a panneural transcription factor that modulates homeodomain protein activity. Proc Natl Acad Sci U S A (1997) 1.08
Cellular studies of auditory hair cell regeneration in birds. Proc Natl Acad Sci U S A (2000) 1.07
Antagonistic action of Six3 and Prox1 at the gamma-crystallin promoter. Nucleic Acids Res (2001) 1.03
An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes. Mol Cell Biol (2004) 1.00
The new era of the lymphatic system: no longer secondary to the blood vascular system. Cold Spring Harb Perspect Med (2012) 0.97
Eyes absent: a gene family found in several metazoan phyla. Mamm Genome (1997) 0.94
Eye on regeneration. Anat Rec B New Anat (2005) 0.91
A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development. J Vasc Res (2010) 0.88
Separation of the PROX1 gene from upstream conserved elements in a complex inversion/translocation patient with hypoplastic left heart. Eur J Hum Genet (2009) 0.88
Dual roles for Prox1 in the regulation of the chicken betaB1-crystallin promoter. Invest Ophthalmol Vis Sci (2008) 0.87
Characterization of Prox1 and VEGFR-3 expression and lymphatic phenotype in normal organs of mice lacking p50 subunit of NF-κB. Microcirculation (2011) 0.82
Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression. Development (2015) 0.81
Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specification. Front Cell Neurosci (2015) 0.81
The carboxy terminus of Prospero regulates its subcellular localization. Mol Cell Biol (2003) 0.80
Location of the Prox1 gene expression during newt lens and retina regeneration. Dokl Biol Sci (2003) 0.75
Arrest of segregation leads to accumulation of highly intertwined catenated dimers: dissection of the final stages of SV40 DNA replication. Cell (1981) 4.58
Terminal stages of SV40 DNA replication proceed via multiply intertwined catenated dimers. Cell (1980) 4.32
Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. Annu Rev Biochem (1988) 4.01
A stretch of "late" SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes. Cell (1979) 3.96
Lens differentiation in vertebrates. A review of cellular and molecular features. Differentiation (1981) 3.65
Oncogenesis of the lens in transgenic mice. Science (1987) 3.40
Alternative RNA splicing of the murine alpha A-crystallin gene: protein-coding information within an intron. Cell (1983) 3.32
The cellular basis of corneal transparency: evidence for 'corneal crystallins'. J Cell Sci (1999) 2.55
Recruitment of enzymes as lens structural proteins. Science (1987) 2.25
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. Proc Natl Acad Sci U S A (1985) 2.22
Genetic basis of total colourblindness among the Pingelapese islanders. Nat Genet (2000) 2.18
Expression of the murine alpha B-crystallin gene is not restricted to the lens. Mol Cell Biol (1989) 2.12
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet (2000) 2.00
Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome. Nat Genet (2000) 1.99
Lens development and crystallin gene expression: many roles for Pax-6. Bioessays (1996) 1.87
Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Autism Res (2009) 1.80
Abnormalities in the p34cdc2-related PITSLRE protein kinase gene complex (CDC2L) on chromosome band 1p36 in melanoma. Cancer Genet Cytogenet (1999) 1.71
Isolation of a novel candidate oncogene within a frequently amplified region at 3q26 in ovarian cancer. Cancer Res (2001) 1.66
Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry (1995) 1.66
Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia. Proc Natl Acad Sci U S A (1985) 1.65
Mutational analysis and clinical correlation in Leber congenital amaurosis. Ophthalmic Genet (2000) 1.65
Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. Invest Ophthalmol Vis Sci (1997) 1.62
The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia. Invest Ophthalmol Vis Sci (1997) 1.61
IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. J Biol Chem (1999) 1.57
Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: implications for stepwise determination of the lens. Dev Biol (1994) 1.55
Sequence and location of SIX3, a homeobox gene expressed in the human eye. Ophthalmic Genet (1999) 1.49
Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. J Cell Sci (2000) 1.43
Gene and protein structure of a beta-crystallin polypeptide in murine lens: relationship of exons and structural motifs. Nature (1983) 1.37
Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes. Mol Cell Biol (1990) 1.36
Lens crystallins of invertebrates--diversity and recruitment from detoxification enzymes and novel proteins. Eur J Biochem (1996) 1.35
Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues. Adv Enzymol Relat Areas Mol Biol (1994) 1.32
Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1. Am J Hum Genet (2001) 1.32
Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells. Eur J Biochem (1995) 1.31
Staphylococcal nuclease makes a single non-random cut in the simian virus 40 viral minichromosome. J Mol Biol (1979) 1.31
Squid Pax-6 and eye development. Proc Natl Acad Sci U S A (1997) 1.31
Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site. Mol Cell Biol (1995) 1.31
Evidence for positive and negative regulation in the promoter of the chicken delta 1-crystallin gene. Dev Biol (1988) 1.30
Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific beta-crystallin genes. Mol Cell Biol (1998) 1.30
C(2)H(4) metabolism in morning glory flowers. Plant Physiol (1978) 1.29
The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes. Proc Natl Acad Sci U S A (1998) 1.29
Tau-crystallin/alpha-enolase: one gene encodes both an enzyme and a lens structural protein. J Cell Biol (1988) 1.29
Modulation of myocilin/TIGR expression in human trabecular meshwork. Invest Ophthalmol Vis Sci (1999) 1.29
Two-year results of a controlled study of residential rehabilitation for patients treated with percutaneous transluminal coronary angioplasty. A randomized study of a multifactorial programme. Eur Heart J (1999) 1.28
Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells. J Biol Chem (1996) 1.25
Protein synthesis and ultrastructure during the formation of embryonic chick lens fibers in vivo and in vitro. Dev Biol (1972) 1.25
Confirmation of assignment of the human alpha 1-crystallin gene (CRYA1) to chromosome 21 with regional localization to q22.3. Hum Genet (1987) 1.25
Intensive group cognitive treatment and individual cognitive therapy vs. treatment as usual in social phobia: a randomized controlled trial. Acta Psychiatr Scand (2007) 1.24
Lens-specific promoter activity of a mouse gamma-crystallin gene. Mol Cell Biol (1985) 1.24
Delta crystallins and their nucleic acids. Mol Cell Biochem (1984) 1.24
A pseudo-exon in the functional human alpha A-crystallin gene. Nature (1989) 1.23
Lens crystallins and their gene families. Cell (1984) 1.23
Human alpha B-crystallin gene and preferential promoter function in lens. Genomics (1990) 1.19
Gender differences in the risk of coronary artery disease in iran. Iran J Public Health (2012) 1.17
Aldehyde dehydrogenase-derived omega-crystallins of squid and octopus. Specialization for lens expression. J Biol Chem (1993) 1.16
The complete sequence of the chicken delta 1 crystallin gene and its 5' flanking region. J Biol Chem (1985) 1.15
A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins. Mol Cell Biol (1994) 1.15
Amplification of 19q13.1-q13.2 sequences in ovarian cancer. G-band, FISH, and molecular studies. Cancer Genet Cytogenet (1996) 1.15
Differentiation of lens fibers in explanted embryonic chick lens epithelia. Dev Biol (1973) 1.14
alpha A-crystallin messenger RNA of the mouse lens: more noncoding than coding sequences. Science (1982) 1.13
Clonal chromosome abnormalities in human breast carcinomas. II. Thirty-four cases with metastatic disease. Genes Chromosomes Cancer (1993) 1.13
Chicken lens crystallin DNA sequences show at least two delta-crystallin genes. Nature (1980) 1.13
Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization. J Biol Chem (2001) 1.12
Quantitation of delta-crystallin messenger RNA during lens induction in chick embryos. Proc Natl Acad Sci U S A (1976) 1.12
Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 alpha subunit kinase: homology to protein kinases. Proc Natl Acad Sci U S A (1991) 1.12
Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. Proc Natl Acad Sci U S A (1995) 1.11
Differential display detects altered gene expression between cataractous and normal human lenses. Invest Ophthalmol Vis Sci (1998) 1.11
Transketolase is a major protein in the mouse cornea. J Biol Chem (1996) 1.10
The role of MAP4 expression in the sensitivity to paclitaxel and resistance to vinca alkaloids in p53 mutant cells. Oncogene (1998) 1.10
Structure and chromosomal localization of the human homeobox gene Prox 1. Genomics (1996) 1.10
Structural and functional evidence for differential promoter activity of the two linked delta-crystallin genes in the chicken. EMBO J (1985) 1.09
A mutation in the V1 end domain of keratin 1 in non-epidermolytic palmar-plantar keratoderma. J Invest Dermatol (1994) 1.09
Magnifying endoscopy in gastritis of the corpus. Endoscopy (2005) 1.08
Common core sequences are found in skeletal muscle slow- and fast-fiber-type-specific regulatory elements. Mol Cell Biol (1996) 1.08
Analysis of the mouse gamma-crystallin gene family: assignment of multiple cDNAs to discrete genomic sequences and characterization of a representative gene. Nucleic Acids Res (1984) 1.08
Involvement of retinoic acid/retinoid receptors in the regulation of murine alphaB-crystallin/small heat shock protein gene expression in the lens. J Biol Chem (1998) 1.08
Regulation of the murine alpha A-crystallin promoter in transgenic mice. Dev Biol (1990) 1.08
Inhibition of protein synthesis in insect cells by baculovirus-expressed heme-regulated eIF-2 alpha kinase. J Biol Chem (1994) 1.08
Transcription and site-specific hypomethylation of the delta-crystallin genes in the embryonic chicken lens. J Biol Chem (1981) 1.07
Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells. Differentiation (1986) 1.07
Alpha-crystallin/small heat shock protein has autokinase activity. Proc Natl Acad Sci U S A (1994) 1.07
A case of combined gastrojejunal and gastrocolic fistula secondary to gastric cancer. J Korean Med Sci (1996) 1.07
Abundant mRNAs in the squid light organ encode proteins with a high similarity to mammalian peroxidases. Gene (1993) 1.06
Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme. J Biol Chem (1989) 1.06
Molecular weight and subunit structure of delta-crystallin from embryonic chick lens fibers. Exp Eye Res (1974) 1.06
Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. Am J Hum Genet (2007) 1.06
Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene. Biochem Biophys Res Commun (2000) 1.06
An immunohistochemical method for the detection of proteins in the vertebrate lens. J Immunol Methods (2001) 1.06
Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments. Mol Biol Cell (2000) 1.05
Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants. Nucleic Acids Res (2000) 1.05
Synthesis of O-glycan core 3: characterization of UDP-GlcNAc: GalNAc-R beta 3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines. Glycobiology (1995) 1.05
Sequence of the chicken delta 2 crystallin gene and its intergenic spacer. Extreme homology with the delta 1 crystallin gene. J Biol Chem (1986) 1.05
Molecular cloning and partial characterization of delta-crystallin cDNA sequences in a bacterial plasmid. Proc Natl Acad Sci U S A (1979) 1.05
Rates of protein synthesis in explanted embryonic chick lens epithelia: differential stimulation of delta-crystallin synthesis. Dev Biol (1975) 1.05
DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4. Cancer Res (1999) 1.05
Crystallins of the octopus lens. Recruitment from detoxification enzymes. J Biol Chem (1991) 1.04
MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene. Oncogene (2012) 1.04
Taxon-specific recruitment of enzymes as major soluble proteins in the corneal epithelium of three mammals, chicken, and squid. Proc Natl Acad Sci U S A (1992) 1.04
Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells. J Clin Invest (2000) 1.04
Comparison of two delta-crystallin genes in the chicken. Proc Natl Acad Sci U S A (1980) 1.04