Published in Neuroreport on June 17, 1996
Cytokine, sickness behavior, and depression. Neurol Clin (2006) 1.58
Cytokine, sickness behavior, and depression. Immunol Allergy Clin North Am (2009) 1.56
Immune-neural connections: how the immune system's response to infectious agents influences behavior. J Exp Biol (2013) 1.48
The inflammasome: pathways linking psychological stress, depression, and systemic illnesses. Brain Behav Immun (2012) 1.42
Parkinson's disease and systemic inflammation. Parkinsons Dis (2011) 0.96
Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness. Proc Natl Acad Sci U S A (2005) 0.92
A relationship between oxytocin and anxiety of romantic attachment. Clin Pract Epidemiol Ment Health (2006) 0.89
Sleep Health: Reciprocal Regulation of Sleep and Innate Immunity. Neuropsychopharmacology (2016) 0.88
Central infusion of interleukin-1 receptor antagonist blocks the reduction in social behavior produced by prior stressor exposure. Physiol Behav (2009) 0.88
The TRPV1 channel in rodents is a major target for antinociceptive effect of the probiotic Lactobacillus reuteri DSM 17938. J Physiol (2015) 0.86
The role of the ventral striatum in inflammatory-induced approach toward support figures. Brain Behav Immun (2014) 0.85
Inflammation at the intersection of behavior and somatic symptoms. Psychiatr Clin North Am (2011) 0.83
Effect of subdiaphragmatic vagotomy on the noradrenergic and HPA axis activation induced by intraperitoneal interleukin-1 administration in rats. Brain Res (2006) 0.83
Can consuming flavonoids restore old microglia to their youthful state? Nutr Rev (2010) 0.83
Photoperiodic regulation of behavioral responsiveness to proinflammatory cytokines. Physiol Behav (2007) 0.82
Feeding the beast: can microglia in the senescent brain be regulated by diet? Brain Behav Immun (2014) 0.81
Fasting Induces IL-1 Resistance and Free-Fatty Acid-Mediated Up-Regulation of IL-1R2 and IL-1RA. Front Immunol (2014) 0.80
Mechanisms of microglial activation in models of inflammation and hypoxia: Implications for chronic intermittent hypoxia. J Physiol (2016) 0.77
Neuroimmune mechanisms of behavioral alterations in a syngeneic murine model of human papilloma virus-related head and neck cancer. Psychoneuroendocrinology (2017) 0.75
The role of B cells and autoantibodies in neuropsychiatric lupus. Autoimmun Rev (2016) 0.75
Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB J (2005) 3.84
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Mol Psychiatry (2008) 3.28
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy. Mol Psychiatry (2002) 2.87
Sickness behavior as a new target for drug development. Trends Pharmacol Sci (1992) 2.42
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry (2009) 2.36
Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide. Neurobiol Aging (2007) 2.03
A new concept in neurodegeneration: TNFalpha is a silencer of survival signals. Trends Neurosci (2000) 1.93
Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res Mol Brain Res (1994) 1.90
A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide. Proc Natl Acad Sci U S A (1999) 1.90
Interleukin-10 in the brain. Crit Rev Immunol (2001) 1.89
Stress and immunity: an integrated view of relationships between the brain and the immune system. Life Sci (1989) 1.70
Body surface area of female swine. J Anim Sci (1973) 1.70
Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alfa-2b therapy. J Clin Oncol (2000) 1.57
A novel role of growth hormone and insulin-like growth factor-I. Priming neutrophils for superoxide anion secretion. J Immunol (1991) 1.55
Modulation of social memory in male rats by neurohypophyseal peptides. Psychopharmacology (Berl) (1987) 1.49
Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. Proc Natl Acad Sci U S A (1992) 1.49
Role of interleukin-1beta and tumour necrosis factor-alpha in lipopolysaccharide-induced sickness behaviour: a study with interleukin-1 type I receptor-deficient mice. Eur J Neurosci (2000) 1.43
Cytokine signals propagate through the brain. Mol Psychiatry (2000) 1.42
Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent? Auton Neurosci (2000) 1.41
Molecular basis of sickness behavior. Ann N Y Acad Sci (1998) 1.39
Requirement for phosphatidylinositol 3'-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. J Immunol (1996) 1.39
Association between immune activation and early depressive symptoms in cancer patients treated with interleukin-2-based therapy. Psychoneuroendocrinology (2001) 1.37
Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Res (1992) 1.37
The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen. Brain Behav Immun (2002) 1.35
Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120. Neurobiol Aging (2006) 1.33
Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism. C R Acad Sci III (1994) 1.33
IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3'-kinase. J Immunol (2001) 1.33
Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression. Am J Physiol Regul Integr Comp Physiol (2000) 1.33
Cytokines and sickness behavior. Ann N Y Acad Sci (1998) 1.32
Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice. Physiol Behav (2000) 1.32
Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice. Psychoneuroendocrinology (1994) 1.31
Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthase in rat brain. Neuroscience (1999) 1.31
Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS. Am J Physiol (1995) 1.29
Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats. Psychoneuroendocrinology (1999) 1.28
GH3 pituitary adenoma cells can reverse thymic aging in rats. Proc Natl Acad Sci U S A (1986) 1.24
Prolactin synthesized and secreted by human peripheral blood mononuclear cells: an autocrine growth factor for lymphoproliferation. Proc Natl Acad Sci U S A (1992) 1.23
The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis. Eur J Neurosci (2000) 1.23
Gonadal steroids influence the involvement of arginine vasopressin in social recognition in mice. Psychoneuroendocrinology (1993) 1.22
Newcastle disease virus as an antineoplastic agent: induction of tumor necrosis factor-alpha and augmentation of its cytotoxicity. J Natl Cancer Inst (1988) 1.20
Timing and specificity of the cognitive changes induced by interleukin-2 and interferon-alpha treatments in cancer patients. Psychosom Med (2001) 1.20
Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice. Brain Behav Immun (1997) 1.17
Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats. Am J Physiol (1999) 1.14
Social recognition does not involve vasopressinergic neurotransmission in female rats. Brain Res (1990) 1.13
Pyrogens specifically disrupt the acquisition of a task involving cognitive processing in the rat. Brain Behav Immun (1995) 1.13
Stress and immune function: a bibliographic review. Ann Rech Vet (1980) 1.12
Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. Eur J Neurosci (2008) 1.12
Androgen-dependent vasopressinergic neurons are involved in social recognition in rats. Brain Res (1990) 1.11
Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene. J Exp Med (1986) 1.10
Vagotomy blocks behavioural effects of interleukin-1 injected via the intraperitoneal route but not via other systemic routes. Neuroreport (1996) 1.09
Central administration of insulin-like growth factor-1 inhibits lipopolysaccharide-induced sickness behavior in mice. Neuroreport (1999) 1.09
Effects of aerial ammonia, hydrogen sulfide and swine-house dust on rate of gain and respiratory-tract structure in swine. J Anim Sci (1975) 1.07
A newly defined property of somatotropin: priming of macrophages for production of superoxide anion. Science (1988) 1.06
Diurnal and annual fluctuations of aerial bacterial and dust levels in enclosed swine houses. J Anim Sci (1975) 1.04
Stress in farm animals: a need for reevaluation. J Anim Sci (1983) 1.04
Behavioural effects of peripherally injected interleukin-1: role of prostaglandins. Brain Res (1991) 1.04
Attentional and mnemonic deficits associated with infectious disease in humans. Psychol Med (1999) 1.04
Lipopolysaccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism. Brain Behav Immun (1995) 1.04
Centrally injected arginine vasopressin (AVP) facilitates social memory in rats. Neurosci Lett (1987) 1.03
Interferon-gamma-induced priming for secretion of superoxide anion and tumor necrosis factor-alpha declines in macrophages from aged rats. FASEB J (1990) 1.03
Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor. J Clin Invest (1992) 1.01
Murine macrophages express abundant insulin-like growth factor-I class I Ea and Eb transcripts. Endocrinology (1993) 1.01
Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta. Eur Cytokine Netw (1998) 1.01
Interleukin-1 mediates behavioural but not metabolic effects of tumor necrosis factor alpha in mice. Eur J Pharmacol (1991) 1.01
Mechanisms of sickness-induced decreases in food-motivated behavior. Neurosci Biobehav Rev (1996) 0.99
Adrenalectomy enhances pro-inflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide. Brain Res Mol Brain Res (1996) 0.98
Central and peripheral prostaglandins are involved in sickness behavior in birds. Physiol Behav (1993) 0.98
Stress-induced alterations in delayed-type hypersensitivity to SRBC and contact sensitivity to DNFB in mice. Proc Soc Exp Biol Med (1982) 0.98
In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. Endocrinology (1998) 0.97
Differential effects of IL-1ra on sickness behavior and weight loss induced by IL-1 in rats. Brain Res (1995) 0.97
Induction of IL-2 and lymphokine activated killer cells in the cat. Vet Immunol Immunopathol (1987) 0.97
The pituitary gland is required for protection against lethal effects of Salmonella typhimurium. Proc Natl Acad Sci U S A (1991) 0.97
Role of interferon-gamma in counteracting the suppressive effects of transforming growth factor-beta 2 and glucocorticoids on the production of tumor necrosis factor-alpha. J Leukoc Biol (1990) 0.97
Social and individual recognition in rodents: Methodological aspects and neurobiological bases. Behav Processes (2002) 0.97