Bile acid transport systems as pharmaceutical targets.

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Bile acid transporters in health and disease. Xenobiotica (2008) 1.24

The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships. Naunyn Schmiedebergs Arch Pharmacol (2006) 1.23

Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut (2004) 1.15

Role of the intestinal bile acid transporters in bile acid and drug disposition. Handb Exp Pharmacol (2011) 1.14

Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter. Mol Pharm (2006) 1.03

Drug transporters in pharmacokinetics. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.91

Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT. Int J Pharm (2010) 0.78

Plasma membrane transporters in modern liver pharmacology. Scientifica (Cairo) (2012) 0.78

Electrogenicity of Na(+)-coupled bile acid transporters. Yale J Biol Med (1998) 0.77

Fatty acid bile acid conjugates (FABACs)--new molecules for the prevention of cholesterol crystallisation in bile. Gut (2001) 0.76

How we have learned about the complexity of physiology, pathobiology and pharmacology of bile acids and biliary secretion. World J Gastroenterol (2008) 0.75

Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST study. J Vet Intern Med (2008) 1.81

Intestinal bile acid absorption. Na(+)-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93-kDa and a peripheral 14-kDa bile acid-binding membrane protein along the duodenum-ileum axis. J Biol Chem (1993) 1.08

Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas. Gastroenterology (1997) 1.05

Liver-specific drug targeting by coupling to bile acids. J Biol Chem (1992) 0.93

Characterization and chemical modification of the Na(+)-dependent bile-acid transport system in brush-border membrane vesicles from rabbit ileum. Biochim Biophys Acta (1992) 0.90

Breed differences in natriuretic peptides in healthy dogs. J Vet Intern Med (2014) 0.87

Bile acid derived HMG-CoA reductase inhibitors. Biochim Biophys Acta (1994) 0.87

Intestinal absorption of peptides by coupling to bile acids. J Biol Chem (1994) 0.86

Topological photoaffinity labeling of the rabbit ileal Na+/bile-salt-cotransport system. Eur J Biochem (1997) 0.82

Simpson's method of discs for measurement of echocardiographic end-diastolic and end-systolic left ventricular volumes: breed-specific reference ranges in Boxer dogs. J Vet Intern Med (2013) 0.80

Identification of the bile acid binding proteins in human serum by photoaffinity labeling. Biochim Biophys Acta (1995) 0.79

Home monitoring of blood glucose concentration by owners of diabetic dogs. J Small Anim Pract (2003) 0.79

Nutritional secondary hyperparathyroidism in six cats. J Small Anim Pract (1999) 0.79

The rabbit ileal lipid-binding protein. Gene cloning and functional expression of the recombinant protein. Eur J Biochem (1996) 0.79

Longitudinal analysis of quality of life, clinical, radiographic, echocardiographic, and laboratory variables in dogs with myxomatous mitral valve disease receiving pimobendan or benazepril: the QUEST study. J Vet Intern Med (2013) 0.78

Serum cardiac troponin I concentrations in dogs with systemic inflammatory response syndrome. J Vet Intern Med (2015) 0.78

Bile acid-oligodeoxynucleotide conjugates: synthesis and liver excretion in rats. Bioorg Med Chem Lett (2001) 0.77

Hepatobiliary transport of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors conjugated with bile acids. Hepatology (1995) 0.76

Serum microRNA profiles in cats with hypertrophic cardiomyopathy. Mol Cell Biochem (2015) 0.76

Sphericity index and E-point-to-septal-separation (EPSS) to diagnose dilated cardiomyopathy in Doberman Pinschers. J Vet Intern Med (2013) 0.75

The role of hypothyroidism in the etiology and progression of dilated cardiomyopathy in Doberman Pinschers. J Vet Intern Med (2014) 0.75

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Drug discovery opportunities. Ernst Schering Res Found Workshop (2003) 0.75

Synthesis and biological activity of new leukotriene antagonists. Prog Clin Biol Res (1989) 0.75

A new technique for insertion of esophagostomy tubes in cats. J Am Anim Hosp Assoc (2001) 0.75

Synthesis and biological activity of new leukotriene antagonists (racemates and enantiomerically pure compounds). Biomed Biochim Acta (1988) 0.75