Published in J Comp Neurol on September 30, 1996
Lithium delays progression of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2008) 5.37
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A (2002) 4.37
Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc Natl Acad Sci U S A (1998) 1.23
Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. Proc Natl Acad Sci U S A (2005) 1.19
Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc Natl Acad Sci U S A (1998) 1.11
Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis. J Neurol (2000) 1.10
Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS). PLoS One (2011) 1.00
A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis. Antioxid Redox Signal (2009) 0.96
Alterations in the motor neuron-renshaw cell circuit in the Sod1(G93A) mouse model. J Comp Neurol (2013) 0.91
Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1. Proc Natl Acad Sci U S A (2000) 0.86
Amyotrophic lateral sclerosis: Protein chaperone dysfunction revealed by proteomic studies of animal models. Proteomics Clin Appl (2008) 0.76
Glycoprotein staining following electrophoresis on acrylamide gels. Anal Biochem (1969) 12.65
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature (1998) 6.29
Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A (1980) 5.47
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology (2003) 3.62
Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices. J Neurosci (1987) 3.39
Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa. Neuron (1992) 3.25
Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease. Science (1987) 3.07
Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience (2004) 3.06
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (1995) 2.79
Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease. J Neurosci (1985) 2.72
Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J Neurosci (2000) 2.51
Integration and stable germ line transmission of genes injected into mouse pronuclei. Science (1981) 2.31
Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol (1983) 2.23
Certain Molar Movements of the Human Body produced by the Circulation of the Blood. J Anat Physiol (1877) 1.88
Retracted Amyloid plaques, neurofibrillary tangles and neuronal loss in brains of transgenic mice overexpressing a C-terminal fragment of human amyloid precursor protein. Nature (1991) 1.76
Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: a quantitative evaluation of a one-year autopsy population from a geriatric hospital. Cereb Cortex (1994) 1.73
Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience (2009) 1.68
Different modes of hippocampal plasticity in response to estrogen in young and aged female rats. Proc Natl Acad Sci U S A (2001) 1.64
Atypical form of Alzheimer's disease with prominent posterior cortical atrophy: a review of lesion distribution and circuit disconnection in cortical visual pathways. Vision Res (1997) 1.59
Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: I. Superior frontal and inferior temporal cortex. J Comp Neurol (1990) 1.58
Monoclonal antibody to neurofilament protein (SMI-32) labels a subpopulation of pyramidal neurons in the human and monkey neocortex. J Comp Neurol (1989) 1.55
Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proc Natl Acad Sci U S A (1994) 1.55
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage. Cell (1991) 1.54
Localization of glucocorticoid receptors at postsynaptic membranes in the lateral amygdala. Neuroscience (2005) 1.53
Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration. Proc Natl Acad Sci U S A (1995) 1.52
Activity-regulated cytoskeletal-associated protein is localized to recently activated excitatory synapses. Neuroscience (2004) 1.49
Differential regulation of NMDAR1 mRNA and protein by estradiol in the rat hippocampus. J Neurosci (1996) 1.48
Magnocellular and parvocellular visual pathways are both affected in a macaque monkey model of glaucoma. Aust N Z J Ophthalmol (1997) 1.47
Hypobetalipoproteinemia due to an apolipoprotein B gene exon 21 deletion derived by Alu-Alu recombination. J Biol Chem (1989) 1.47
Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: II. Primary and secondary visual cortex. J Comp Neurol (1990) 1.45
Balint's syndrome in Alzheimer's disease: specific disruption of the occipito-parietal visual pathway. Brain Res (1989) 1.43
Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease. Proc Natl Acad Sci U S A (1988) 1.43
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol (1992) 1.38
Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys. Proc Natl Acad Sci U S A (1996) 1.37
Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome. J Neuropathol Exp Neurol (1990) 1.36
Regulation of Thy-1 gene expression in transgenic mice. Cell (1987) 1.35
Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus. J Comp Neurol (2000) 1.34
Neurofilament protein defines regional patterns of cortical organization in the macaque monkey visual system: a quantitative immunohistochemical analysis. J Comp Neurol (1995) 1.30
Feature article: are neurons lost from the primate cerebral cortex during normal aging? Cereb Cortex (1998) 1.29
The distribution of tyrosine hydroxylase-immunoreactive fibers in primate neocortex is widespread but regionally specific. J Neurosci (1987) 1.29
Hippocampal dependent learning ability correlates with N-methyl-D-aspartate (NMDA) receptor levels in CA3 neurons of young and aged rats. J Comp Neurol (2001) 1.28
Neurochemical phenotype of corticocortical connections in the macaque monkey: quantitative analysis of a subset of neurofilament protein-immunoreactive projection neurons in frontal, parietal, temporal, and cingulate cortices. J Comp Neurol (1995) 1.27
Spindle neurons of the human anterior cingulate cortex. J Comp Neurol (1995) 1.27
Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders. Acta Neuropathol (1994) 1.26
Enzymatic amplification of a Y chromosome repeat in a single blastomere allows identification of the sex of preimplantation mouse embryos. Proc Natl Acad Sci U S A (1990) 1.25
Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease. Neuroscience (2003) 1.22
Age-related distribution of neuropathologic changes in the cerebral cortex of patients with Down's syndrome. Quantitative regional analysis and comparison with Alzheimer's disease. Arch Neurol (1995) 1.22
The perceptual attack time of musical tones. J Acoust Soc Am (1987) 1.21
Insertional mutation in a transgenic mouse allelic with Purkinje cell degeneration. Proc Natl Acad Sci U S A (1989) 1.20
Distribution of precursor amyloid-beta-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neuritic plaques. Proc Natl Acad Sci U S A (1988) 1.17
Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in G86R superoxide dismutase transgenic mice. J Comp Neurol (2000) 1.17
Differential vulnerability of neurochemically identified subpopulations of retinal neurons in a monkey model of glaucoma. Brain Res (1995) 1.16
Vasoactive intestinal polypeptide induces glycogenolysis in mouse cortical slices: a possible regulatory mechanism for the local control of energy metabolism. Proc Natl Acad Sci U S A (1981) 1.16
Quantitative neuropathologic analysis of Pick's disease cases: cortical distribution of Pick bodies and coexistence with Alzheimer's disease. Acta Neuropathol (1994) 1.16
Noradrenergic and serotoninergic innervation of cortical, thalamic, and tectal visual structures in Old and New World monkeys. J Comp Neurol (1986) 1.15
Synaptic distribution of the AMPA-GluR2 subunit and its colocalization with calcium-binding proteins in rat cerebral cortex: an immunohistochemical study using a GluR2-specific monoclonal antibody. Exp Neurol (1996) 1.14
Quantitative analysis of the dendritic morphology of corticocortical projection neurons in the macaque monkey association cortex. Neuroscience (2002) 1.14
Extrathalamic modulation of cortical function. Annu Rev Neurosci (1987) 1.13
Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of Alzheimer's type. Neurosci Lett (1983) 1.12
Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients. Nature (1985) 1.11
Preserved number of entorhinal cortex layer II neurons in aged macaque monkeys. Neurobiol Aging (1997) 1.10
An experimental analysis of the origins of somatostatin-like immunoreactivity in the dentate gyrus of the rat. J Neurosci (1986) 1.09
Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex. J Biol Chem (1994) 1.08
DNA-mediated genetic transformation of mouse embryos and bone marrow--a review. Gene (1985) 1.08
Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease. Neuroscience (2002) 1.08
Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus. Neuroscience (2008) 1.08
A monoclonal antibody to non-phosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease. Brain Res (1987) 1.06
Interactive effects of age and estrogen on cortical neurons: implications for cognitive aging. Neuroscience (2011) 1.06
The distribution and orientation of noradrenergic fibers in neocortex of the rat: an immunofluorescence study. J Comp Neurol (1978) 1.04
Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice. J Comp Neurol (1998) 1.02
The neurobiology of aging. Epilepsy Res (2005) 1.02
Distribution of parvalbumin immunoreactivity in the visual cortex of Old World monkeys and humans. J Comp Neurol (1990) 1.02
An immunohistochemical characterization of somatostatin-28 and somatostatin-281-12 in monkey prefrontal cortex. J Comp Neurol (1986) 1.02
Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease. Exp Neurol (1991) 1.01
Parvalbumin-immunoreactive neurons in the neocortex are resistant to degeneration in Alzheimer's disease. J Neuropathol Exp Neurol (1991) 1.01
Arylamine N-acetyltransferase in human red blood cells. Biochem Pharmacol (1992) 1.01
Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: evidence for the implication of the p53 signaling pathway. Neurobiol Dis (2000) 1.01
Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells. J Biol Chem (1997) 1.01
A specific and sensitive assay for aminoguanidine: its application to a study of the disposition of aminoguanidine in animal tissues. J Pharmacol Exp Ther (1969) 1.01
Immunohistochemical distribution of pro-somatostatin-related peptides in cerebral cortex. Brain Res (1983) 1.01
Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7. J Neurosci (1993) 1.01
Neurochemical, morphologic, and laminar characterization of cortical projection neurons in the cingulate motor areas of the macaque monkey. J Comp Neurol (1996) 1.00
Differential subcellular regulation of NMDAR1 protein and mRNA in dendrites of dentate gyrus granule cells after perforant path transection. J Neurosci (1997) 1.00
Neurofilament protein is differentially distributed in subpopulations of corticocortical projection neurons in the macaque monkey visual pathways. J Comp Neurol (1996) 0.99
Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes. Neurosci Lett (1993) 0.99
The distribution and morphological characteristics of the intracortical VIP-positive cell: an immunohistochemical analysis. Brain Res (1984) 0.99
Human orbitofrontal cortex: cytoarchitecture and quantitative immunohistochemical parcellation. J Comp Neurol (1995) 0.98
Distribution of choline acetyltransferase-, serotonin-, dopamine-beta-hydroxylase-, tyrosine hydroxylase-immunoreactive fibers in monkey primary auditory cortex. J Comp Neurol (1987) 0.97
Superoxide dismutase and neurofilament transgenic models of amyotrophic lateral sclerosis. J Exp Zool (1998) 0.97
Immunohistochemical identification of thrombospondin in normal human brain and in Alzheimer's disease. Am J Pathol (1992) 0.97
Length of postovariectomy interval and age, but not estrogen replacement, regulate N-methyl-D-aspartate receptor mRNA levels in the hippocampus of female rats. Exp Neurol (2001) 0.97
alpha-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A- and NR2B-containing N-methyl-d-aspartate receptors in hippocampus. Neuroscience (2007) 0.96
Laminar, tangential and regional organization of the noradrenergic innervation of monkey cortex: dopamine-beta-hydroxylase immunohistochemistry. Brain Res Bull (1983) 0.96
Isolation and analysis of the mouse genomic sequence encoding Cu(2+)-Zn2+ superoxide dismutase. Gene (1991) 0.96
Mitogen-activated protein kinase regulates early phosphorylation and delayed expression of Ca2+/calmodulin-dependent protein kinase II in long-term potentiation. J Neurosci (2001) 0.95